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Treatment Effect of Omalizumab on Severe Pediatric Atopic Dermatitis: The ADAPT Randomized Clinical Trial.

Chan S, Cornelius V, Cro S, Harper JI, Lack G.

JAMA Pediatr. 2019 Nov 25. doi: 10.1001/jamapediatrics.2019.4476. [Epub ahead of print]


A study protocol for testing the feasibility of a randomised stepped wedge cluster design to investigate a Community Health Intervention through Musical Engagement (CHIME) for perinatal mental health in The Gambia.

Sanfilippo KRM, McConnell B, Cornelius V, Darboe B, Huma HB, Gaye M, Ramchandani P, Ceesay H, Glover V, Cross I, Stewart L.

Pilot Feasibility Stud. 2019 Nov 7;5:124. doi: 10.1186/s40814-019-0515-5. eCollection 2019.


Comparison of Clinical Trial Changes in Primary Outcome and Reported Intervention Effect Size Between Trial Registration and Publication.

Chen T, Li C, Qin R, Wang Y, Yu D, Dodd J, Wang D, Cornelius V.

JAMA Netw Open. 2019 Jul 3;2(7):e197242. doi: 10.1001/jamanetworkopen.2019.7242.


The Enhanced Peri-Operative Care for High-risk patients trial: an independent discussion and commentary.

Cornelius V, Johnston CL.

Br J Anaesth. 2019 Sep;123(3):261-266. doi: 10.1016/j.bja.2019.06.003. Epub 2019 Jul 12. No abstract available.


Caprate Modulates Intestinal Barrier Function in Porcine Peyer's Patch Follicle-Associated Epithelium.

Radloff J, Cornelius V, Markov AG, Amasheh S.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1418. doi: 10.3390/ijms20061418.


Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans.

Ojji DB, Mayosi B, Francis V, Badri M, Cornelius V, Smythe W, Kramer N, Barasa F, Damasceno A, Dzudie A, Jones E, Mondo C, Ogah O, Ogola E, Sani MU, Shedul GL, Shedul G, Rayner B, Okpechi IG, Sliwa K, Poulter N; CREOLE Study Investigators.

N Engl J Med. 2019 Jun 20;380(25):2429-2439. doi: 10.1056/NEJMoa1901113. Epub 2019 Mar 18.


Analysis and reporting of adverse events in randomised controlled trials: a review.

Phillips R, Hazell L, Sauzet O, Cornelius V.

BMJ Open. 2019 Mar 1;9(2):e024537. doi: 10.1136/bmjopen-2018-024537.


Cognitive approach to rehabilitation in children with hyperkinetic movement disorders post-DBS.

Gimeno H, Brown RG, Lin JP, Cornelius V, Polatajko HJ.

Neurology. 2019 Mar 12;92(11):e1212-e1224. doi: 10.1212/WNL.0000000000007092. Epub 2019 Feb 22.


How to design a dose-finding study using the continual reassessment method.

Wheeler GM, Mander AP, Bedding A, Brock K, Cornelius V, Grieve AP, Jaki T, Love SB, Odondi L, Weir CJ, Yap C, Bond SJ.

BMC Med Res Methodol. 2019 Jan 18;19(1):18. doi: 10.1186/s12874-018-0638-z.


A randomised controlled feasibility trial to evaluate local heat preconditioning on wound healing after reconstructive breast surgery: the preHEAT trial.

Mehta S, Cro SC, Coomber B, Rolph R, Cornelius V, Farhadi J.

Pilot Feasibility Stud. 2019 Jan 11;5:5. doi: 10.1186/s40814-019-0392-y. eCollection 2019.


A Randomized Crossover Trial of Conventional vs Virtual Chromoendoscopy for Colitis Surveillance: Dysplasia Detection, Feasibility, and Patient Acceptability (CONVINCE).

Gulati S, Dubois P, Carter B, Cornelius V, Martyn M, Emmanuel A, Haji A, Hayee B.

Inflamm Bowel Dis. 2019 May 4;25(6):1096-1106. doi: 10.1093/ibd/izy360.


A small population, randomised, placebo-controlled trial to determine the efficacy of anakinra in the treatment of pustular psoriasis: study protocol for the APRICOT trial.

Cornelius V, Wilson R, Cro S, Barker J, Burden D, Griffiths CEM, Lachmann H, McAteer H, Reynolds N, Pink A, Warren RB, Capon F, Smith C.

Trials. 2018 Aug 29;19(1):465. doi: 10.1186/s13063-018-2841-y.


Automated recruitment and randomisation for an efficient randomised controlled trial in primary care.

Cornelius VR, McDermott L, Forster AS, Ashworth M, Wright AJ, Gulliford MC.

Trials. 2018 Jun 27;19(1):341. doi: 10.1186/s13063-018-2723-3.


Enhanced Invitations Using the Question-Behavior Effect and Financial Incentives to Promote Health Check Uptake in Primary Care.

McDermott L, Cornelius V, Wright AJ, Burgess C, Forster AS, Ashworth M, Khoshaba B, Clery P, Fuller F, Miller J, Dodhia H, Rudisill C, Conner MT, Gulliford MC.

Ann Behav Med. 2018 May 31;52(7):594-605. doi: 10.1093/abm/kax048.


Prevalence estimates and risk factors for early childhood wheeze across Europe: the EuroPrevall birth cohort.

Selby A, Munro A, Grimshaw KE, Cornelius V, Keil T, Grabenhenrich L, Clausen M, Dubakiene R, Fiocchi A, Kowalski ML, Papadopoulos NG, Reche M, Sigurdardottir ST, Sprikkelman AB, Xepapadaki P, Mills ENC, Beyer K, Roberts G.

Thorax. 2018 Nov;73(11):1049-1061. doi: 10.1136/thoraxjnl-2016-209429. Epub 2018 May 10.


eHealth interventions for family carers of people with long term illness: A promising approach?

Sin J, Henderson C, Spain D, Cornelius V, Chen T, Gillard S.

Clin Psychol Rev. 2018 Mar;60:109-125. doi: 10.1016/j.cpr.2018.01.008. Epub 2018 Feb 2. Review.


A cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination.

Forster AS, Cornelius V, Rockliffe L, Marlow LA, Bedford H, Waller J.

Br J Cancer. 2017 Oct 10;117(8):1121-1127. doi: 10.1038/bjc.2017.284. Epub 2017 Aug 22.


Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

Howlin RP, Cathie K, Hall-Stoodley L, Cornelius V, Duignan C, Allan RN, Fernandez BO, Barraud N, Bruce KD, Jefferies J, Kelso M, Kjelleberg S, Rice SA, Rogers GB, Pink S, Smith C, Sukhtankar PS, Salib R, Legg J, Carroll M, Daniels T, Feelisch M, Stoodley P, Clarke SC, Connett G, Faust SN, Webb JS.

Mol Ther. 2017 Sep 6;25(9):2104-2116. doi: 10.1016/j.ymthe.2017.06.021. Epub 2017 Jul 24.


Online versus face-to-face pulmonary rehabilitation for patients with chronic obstructive pulmonary disease: randomised controlled trial.

Bourne S, DeVos R, North M, Chauhan A, Green B, Brown T, Cornelius V, Wilkinson T.

BMJ Open. 2017 Jul 17;7(7):e014580. doi: 10.1136/bmjopen-2016-014580.


Embracing model-based designs for dose-finding trials.

Love SB, Brown S, Weir CJ, Harbron C, Yap C, Gaschler-Markefski B, Matcham J, Caffrey L, McKevitt C, Clive S, Craddock C, Spicer J, Cornelius V.

Br J Cancer. 2017 Jul 25;117(3):332-339. doi: 10.1038/bjc.2017.186. Epub 2017 Jun 29. Review.


Cardiovascular risk at health checks performed opportunistically or following an invitation letter. Cohort study.

Gulliford MC, Khoshaba B, McDermott L, Cornelius V, Ashworth M, Fuller F, Miller J, Dodhia H, Wright AJ.

J Public Health (Oxf). 2018 Jun 1;40(2):e151-e156. doi: 10.1093/pubmed/fdx068.


Effectiveness of psychoeducational interventions for family carers of people with psychosis: A systematic review and meta-analysis.

Sin J, Gillard S, Spain D, Cornelius V, Chen T, Henderson C.

Clin Psychol Rev. 2017 Aug;56:13-24. doi: 10.1016/j.cpr.2017.05.002. Epub 2017 May 29. Review.


The role of anti-IgE (omalizumab/Xolair) in the management of severe recalcitrant paediatric atopic eczema (ADAPT): statistical analysis plan.

Chen T, Chan S, Lack G, Cro S, Cornelius VR.

Trials. 2017 May 23;18(1):231. doi: 10.1186/s13063-017-1976-6.


Resistance to malaria through structural variation of red blood cell invasion receptors.

Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP; Malaria Genomic Epidemiology Network.

Science. 2017 Jun 16;356(6343). pii: eaam6393. doi: 10.1126/science.aam6393. Epub 2017 May 18.


Potential health impact and cost-effectiveness of drug therapy for prehypertension.

Chen T, Yu D, Cornelius V, Qin R, Cai Y, Jiang Z, Zhao Z.

Int J Cardiol. 2017 Aug 1;240:403-408. doi: 10.1016/j.ijcard.2017.05.003. Epub 2017 May 5.


Anxiety after completion of treatment for early-stage breast cancer: a systematic review to identify candidate predictors and evaluate multivariable model development.

Harris J, Cornelius V, Ream E, Cheevers K, Armes J.

Support Care Cancer. 2017 Jul;25(7):2321-2333. doi: 10.1007/s00520-017-3688-6. Epub 2017 Apr 12. Review.


Atopic Dermatitis Anti-IgE Paediatric Trial (ADAPT): the role of anti-IgE in severe paediatric eczema: study protocol for a randomised controlled trial.

Chan S, Cornelius V, Chen T, Radulovic S, Wan M, Jahan R, Lack G.

Trials. 2017 Mar 22;18(1):136. doi: 10.1186/s13063-017-1809-7.


A protocol for a cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination among girls.

Forster AS, Cornelius V, Rockliffe L, Marlow LAV, Bedford H, Waller J.

Pilot Feasibility Stud. 2017 Mar 6;3:13. doi: 10.1186/s40814-017-0126-y. eCollection 2017.


Predictors of rehospitalization in a naturalistic cohort of patients with bipolar affective disorder.

O'Hagan M, Cornelius V, Young AH, Taylor D.

Int Clin Psychopharmacol. 2017 May;32(3):115-120. doi: 10.1097/YIC.0000000000000163.


Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.

Clarke GM, Rockett K, Kivinen K, Hubbart C, Jeffreys AE, Rowlands K, Jallow M, Conway DJ, Bojang KA, Pinder M, Usen S, Sisay-Joof F, Sirugo G, Toure O, Thera MA, Konate S, Sissoko S, Niangaly A, Poudiougou B, Mangano VD, Bougouma EC, Sirima SB, Modiano D, Amenga-Etego LN, Ghansah A, Koram KA, Wilson MD, Enimil A, Evans J, Amodu OK, Olaniyan S, Apinjoh T, Mugri R, Ndi A, Ndila CM, Uyoga S, Macharia A, Peshu N, Williams TN, Manjurano A, Sepúlveda N, Clark TG, Riley E, Drakeley C, Reyburn H, Nyirongo V, Kachala D, Molyneux M, Dunstan SJ, Phu NH, Quyen NN, Thai CQ, Hien TT, Manning L, Laman M, Siba P, Karunajeewa H, Allen S, Allen A, Davis TM, Michon P, Mueller I, Molloy SF, Campino S, Kerasidou A, Cornelius VJ, Hart L, Shah SS, Band G, Spencer CC, Agbenyega T, Achidi E, Doumbo OK, Farrar J, Marsh K, Taylor T, Kwiatkowski DP; MalariaGEN Consortium.

Elife. 2017 Jan 9;6. pii: e15085. doi: 10.7554/eLife.15085.


Enhanced invitation methods and uptake of health checks in primary care: randomised controlled trial and cohort study using electronic health records.

McDermott L, Wright AJ, Cornelius V, Burgess C, Forster AS, Ashworth M, Khoshaba B, Clery P, Fuller F, Miller J, Dodhia H, Rudisill C, Conner MT, Gulliford MC.

Health Technol Assess. 2016 Nov;20(84):1-92.


Genomic analysis of local variation and recent evolution in Plasmodium vivax.

Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J, Amaratunga C, Suon S, Mao S, Noviyanti R, Trimarsanto H, Marfurt J, Anstey NM, William T, Boni MF, Dolecek C, Hien TT, White NJ, Michon P, Siba P, Tavul L, Harrison G, Barry A, Mueller I, Ferreira MU, Karunaweera N, Randrianarivelojosia M, Gao Q, Hubbart C, Hart L, Jeffery B, Drury E, Mead D, Kekre M, Campino S, Manske M, Cornelius VJ, MacInnis B, Rockett KA, Miles A, Rayner JC, Fairhurst RM, Nosten F, Price RN, Kwiatkowski DP.

Nat Genet. 2016 Aug;48(8):959-964. doi: 10.1038/ng.3599. Epub 2016 Jun 27.


The Relationship Between Preoperative Hemoglobin Concentration, Use of Hospital Resources, and Outcomes in Cardiac Surgery.

Hallward G, Balani N, McCorkell S, Roxburgh J, Cornelius V.

J Cardiothorac Vasc Anesth. 2016 Aug;30(4):901-8. doi: 10.1053/j.jvca.2016.02.004. Epub 2016 Feb 12.


Carpal Tunnel Syndrome Associated with Oral Bisphosphonates. A Population-Based Cohort Study.

Carvajal A, Martín Arias LH, Sáinz M, Escudero A, Fierro I, Sauzet O, Cornelius VR, Molokhia M.

PLoS One. 2016 Jan 14;11(1):e0146772. doi: 10.1371/journal.pone.0146772. eCollection 2016.


Antipsychotic use and unexpected death: a hospital-based case-control study.

Mace S, Dzahini O, Cornelius V, Anthony D, Stewart R, Taylor D.

Acta Psychiatr Scand. 2015 Dec;132(6):479-88. doi: 10.1111/acps.12507. Epub 2015 Sep 25.


Genetic determinants of anti-malarial acquired immunity in a large multi-centre study.

Shelton JM, Corran P, Risley P, Silva N, Hubbart C, Jeffreys A, Rowlands K, Craik R, Cornelius V, Hensmann M, Molloy S, Sepulveda N, Clark TG, Band G, Clarke GM, Spencer CC, Kerasidou A, Campino S, Auburn S, Tall A, Ly AB, Mercereau-Puijalon O, Sakuntabhai A, Djimdé A, Maiga B, Touré O, Doumbo OK, Dolo A, Troye-Blomberg M, Mangano VD, Verra F, Modiano D, Bougouma E, Sirima SB, Ibrahim M, Hussain A, Eid N, Elzein A, Mohammed H, Elhassan A, Elhassan I, Williams TN, Ndila C, Macharia A, Marsh K, Manjurano A, Reyburn H, Lemnge M, Ishengoma D, Carter R, Karunaweera N, Fernando D, Dewasurendra R, Drakeley CJ, Riley EM, Kwiatkowski DP, Rockett KA; MalariaGEN Consortium.

Malar J. 2015 Aug 28;14:333. doi: 10.1186/s12936-015-0833-x.


Randomized controlled trial of primary prevention of atopy using house dust mite allergen oral immunotherapy in early childhood.

Zolkipli Z, Roberts G, Cornelius V, Clayton B, Pearson S, Michaelis L, Djukanovic R, Kurukulaaratchy R, Arshad SH.

J Allergy Clin Immunol. 2015 Dec;136(6):1541-1547.e11. doi: 10.1016/j.jaci.2015.04.045. Epub 2015 Jun 12.


Efficacy and Harms of Direct Oral Anticoagulants in the Elderly for Stroke Prevention in Atrial Fibrillation and Secondary Prevention of Venous Thromboembolism: Systematic Review and Meta-Analysis.

Sharma M, Cornelius VR, Patel JP, Davies JG, Molokhia M.

Circulation. 2015 Jul 21;132(3):194-204. doi: 10.1161/CIRCULATIONAHA.114.013267. Epub 2015 May 20. Review.


RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

Masca NG, Hensor EM, Cornelius VR, Buffa FM, Marriott HM, Eales JM, Messenger MP, Anderson AE, Boot C, Bunce C, Goldin RD, Harris J, Hinchliffe RF, Junaid H, Kingston S, Martin-Ruiz C, Nelson CP, Peacock J, Seed PT, Shinkins B, Staples KJ, Toombs J, Wright AK, Teare MD.

Elife. 2015 May 7;4. doi: 10.7554/eLife.05519.


Comparative efficacy and acceptability of drug treatments for bipolar depression: a multiple-treatments meta-analysis.

Taylor DM, Cornelius V, Smith L, Young AH.

Acta Psychiatr Scand. 2014 Dec;130(6):452-69. doi: 10.1111/acps.12343. Epub 2014 Oct 6. Review.


Perineural hematoma may result in nerve inflammation and myelin damage.

Steinfeldt T, Wiesmann T, Nimphius W, Cornelius V, Eismann D, Kratz T, Hadzic A, Wulf H, Werner T.

Reg Anesth Pain Med. 2014 Nov-Dec;39(6):513-9. doi: 10.1097/AAP.0000000000000170.


Prevalence, causes and consequences of compassion satisfaction and compassion fatigue in emergency care: a mixed-methods study of UK NHS Consultants.

Dasan S, Gohil P, Cornelius V, Taylor C.

Emerg Med J. 2015 Aug;32(8):588-94. doi: 10.1136/emermed-2014-203671. Epub 2014 Sep 23.


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