Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 19

1.

Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived Models.

Nadadhur AG, Alsaqati M, Gasparotto L, Cornelissen-Steijger P, van Hugte E, Dooves S, Harwood AJ, Heine VM.

Stem Cell Reports. 2019 Jan 8;12(1):42-56. doi: 10.1016/j.stemcr.2018.11.019. Epub 2018 Dec 20.

2.

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data.

Kluin RJC, Kemper K, Kuilman T, de Ruiter JR, Iyer V, Forment JV, Cornelissen-Steijger P, de Rink I, Ter Brugge P, Song JY, Klarenbeek S, McDermott U, Jonkers J, Velds A, Adams DJ, Peeper DS, Krijgsman O.

BMC Bioinformatics. 2018 Oct 4;19(1):366. doi: 10.1186/s12859-018-2353-5.

3.

Patterning factors during neural progenitor induction determine regional identity and differentiation potential in vitro.

Nadadhur AG, Leferink PS, Holmes D, Hinz L, Cornelissen-Steijger P, Gasparotto L, Heine VM.

Stem Cell Res. 2018 Oct;32:25-34. doi: 10.1016/j.scr.2018.08.017. Epub 2018 Aug 23.

4.

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.

Koppens MA, Bounova G, Cornelissen-Steijger P, de Vries N, Sansom OJ, Wessels LF, van Lohuizen M.

Oncotarget. 2016 Oct 25;7(43):69816-69828. doi: 10.18632/oncotarget.12002.

5.

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.

Koppens MA, Bounova G, Gargiulo G, Tanger E, Janssen H, Cornelissen-Steijger P, Blom M, Song JY, Wessels LF, van Lohuizen M.

Gastroenterology. 2016 Oct;151(4):684-697.e12. doi: 10.1053/j.gastro.2016.06.020. Epub 2016 Jun 21.

PMID:
27342214
6.

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.

Kemper K, Krijgsman O, Kong X, Cornelissen-Steijger P, Shahrabi A, Weeber F, van der Velden DL, Bleijerveld OB, Kuilman T, Kluin RJC, Sun C, Voest EE, Ju YS, Schumacher TNM, Altelaar AFM, McDermott U, Adams DJ, Blank CU, Haanen JB, Peeper DS.

Cell Rep. 2016 Jun 28;16(1):263-277. doi: 10.1016/j.celrep.2016.05.064. Epub 2016 Jun 16.

7.

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.

Kemper K, Krijgsman O, Cornelissen-Steijger P, Shahrabi A, Weeber F, Song JY, Kuilman T, Vis DJ, Wessels LF, Voest EE, Schumacher TN, Blank CU, Adams DJ, Haanen JB, Peeper DS.

EMBO Mol Med. 2015 Sep;7(9):1104-18. doi: 10.15252/emmm.201404914.

8.

Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.

Müller J, Krijgsman O, Tsoi J, Robert L, Hugo W, Song C, Kong X, Possik PA, Cornelissen-Steijger PD, Geukes Foppen MH, Kemper K, Goding CR, McDermott U, Blank C, Haanen J, Graeber TG, Ribas A, Lo RS, Peeper DS.

Nat Commun. 2014 Dec 15;5:5712. doi: 10.1038/ncomms6712.

9.

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

Michalak EM, Nacerddine K, Pietersen A, Beuger V, Pawlitzky I, Cornelissen-Steijger P, Wientjens E, Tanger E, Seibler J, van Lohuizen M, Jonkers J.

Stem Cells. 2013 Sep;31(9):1910-20. doi: 10.1002/stem.1437.

10.

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.

Westerman BA, Blom M, Tanger E, van der Valk M, Song JY, van Santen M, Gadiot J, Cornelissen-Steijger P, Zevenhoven J, Prosser HM, Uren A, Aronica E, van Lohuizen M.

PLoS One. 2012;7(5):e35943. doi: 10.1371/journal.pone.0035943. Epub 2012 May 4.

11.

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

Nacerddine K, Beaudry JB, Ginjala V, Westerman B, Mattiroli F, Song JY, van der Poel H, Ponz OB, Pritchard C, Cornelissen-Steijger P, Zevenhoven J, Tanger E, Sixma TK, Ganesan S, van Lohuizen M.

J Clin Invest. 2012 May;122(5):1920-32. doi: 10.1172/JCI57477. Epub 2012 Apr 16.

12.

BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.

Puppe J, Drost R, Liu X, Joosse SA, Evers B, Cornelissen-Steijger P, Nederlof P, Yu Q, Jonkers J, van Lohuizen M, Pietersen AM.

Breast Cancer Res. 2009;11(4):R63. doi: 10.1186/bcr2354. Epub 2009 Aug 26.

13.

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer.

Pietersen AM, Horlings HM, Hauptmann M, Langerød A, Ajouaou A, Cornelissen-Steijger P, Wessels LF, Jonkers J, van de Vijver MJ, van Lohuizen M.

Breast Cancer Res. 2008;10(6):R109. doi: 10.1186/bcr2214. Epub 2008 Dec 19.

14.

Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium.

Pietersen AM, Evers B, Prasad AA, Tanger E, Cornelissen-Steijger P, Jonkers J, van Lohuizen M.

Curr Biol. 2008 Jul 22;18(14):1094-9. doi: 10.1016/j.cub.2008.06.070.

15.

ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses.

Hamdi M, Popeijus HE, Carlotti F, Janssen JM, van der Burgt C, Cornelissen-Steijger P, van de Water B, Hoeben RC, Matsuo K, van Dam H.

DNA Repair (Amst). 2008 Mar 1;7(3):487-96. doi: 10.1016/j.dnarep.2007.12.004. Epub 2008 Jan 30.

PMID:
18249159
16.

DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.

Hamdi M, Kool J, Cornelissen-Steijger P, Carlotti F, Popeijus HE, van der Burgt C, Janssen JM, Yasui A, Hoeben RC, Terleth C, Mullenders LH, van Dam H.

Oncogene. 2005 Nov 3;24(48):7135-44.

PMID:
16044158
17.

Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2.

Kool J, Hamdi M, Cornelissen-Steijger P, van der Eb AJ, Terleth C, van Dam H.

Oncogene. 2003 Jul 3;22(27):4235-42.

PMID:
12833146
18.

Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes.

Abrahams PJ, Houweling A, Cornelissen-Steijger PD, Jaspers NG, Darroudi F, Meijers CM, Mullenders LH, Filon R, Arwert F, Pinedo HM, Natarajan AP, Terleth C, Van Zeeland AA, van der Eb AJ.

Mutat Res. 1998 Mar;407(2):189-201.

PMID:
9637247
19.

A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients.

Terleth C, van Laar T, Schouten R, van Steeg H, Hodemaekers H, Wormhoudt T, Cornelissen-Steijger PD, Abrahams PJ, van der Eb AJ.

Cancer Res. 1997 Oct 1;57(19):4384-92.

Supplemental Content

Loading ...
Support Center