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Items: 1 to 50 of 127

1.

Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2018 Jun 13. doi: 10.1038/s41586-018-0227-7. [Epub ahead of print]

PMID:
29899441
2.

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms.

Farboud B, Jarvis E, Roth TL, Shin J, Corn JE, Marson A, Meyer BJ, Patel NH, Hochstrasser ML.

J Vis Exp. 2018 May 25;(135). doi: 10.3791/57350.

PMID:
29889198
3.

Apparent Range Expansion of Culicoides (Hoffmania) insignis (Diptera: Ceratopogonidae) in the Southeastern United States.

Vigil SL, Ruder MG, Shaw D, Wlodkowski J, Garrett K, Walter M, Corn JL.

J Med Entomol. 2018 Mar 8. doi: 10.1093/jme/tjy036. [Epub ahead of print]

PMID:
29534230
4.

BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.

Stewart MD, Zelin E, Dhall A, Walsh T, Upadhyay E, Corn JE, Chatterjee C, King MC, Klevit RE.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1316-1321. doi: 10.1073/pnas.1715467115. Epub 2018 Jan 24.

PMID:
29367421
5.

Dosimetric impact of gastrointestinal air column in radiation treatment of pancreatic cancer.

Estabrook NC, Corn JB, Ewing MM, Cardenes HR, Das IJ.

Br J Radiol. 2018 Feb;91(1083):20170512. doi: 10.1259/bjr.20170512. Epub 2017 Dec 22.

PMID:
29166133
6.

E Pluribus Unum ("Out of Many, One"): CRISPR Modeling of Myeloid Expansion.

Shin J, Corn JE.

Cell Stem Cell. 2017 Oct 5;21(4):415-416. doi: 10.1016/j.stem.2017.09.013.

PMID:
28985519
7.

Production of Purified CasRNPs for Efficacious Genome Editing.

Lingeman E, Jeans C, Corn JE.

Curr Protoc Mol Biol. 2017 Oct 2;120:31.10.1-31.10.19. doi: 10.1002/cpmb.43.

PMID:
28967993
8.

Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.

Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, Simeonov DR, Suliman N, Li R, Xu J, Flynn RA, Kundaje A, Khavari PA, Marson A, Corn JE, Quertermous T, Greenleaf WJ, Chang HY.

Nat Genet. 2017 Nov;49(11):1602-1612. doi: 10.1038/ng.3963. Epub 2017 Sep 25.

9.

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2017 Sep 7;549(7670):111-115. doi: 10.1038/nature23875. Epub 2017 Aug 30. Erratum in: Nature. 2018 Jun 13;:.

10.

Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.

Tesar D, Luoma J, Wyatt EA, Shi C, Shatz W, Hass PE, Mathieu M, Yi L, Corn JE, Maass KF, Wang K, Dion MZ, Andersen N, Loyet KM, van Lookeren Campagne M, Rajagopal K, Dickmann L, Scheer JM, Kelley RF.

MAbs. 2017 Nov/Dec;9(8):1297-1305. doi: 10.1080/19420862.2017.1372078. Epub 2017 Aug 30.

11.

Disabling Cas9 by an anti-CRISPR DNA mimic.

Shin J, Jiang F, Liu JJ, Bray NL, Rauch BJ, Baik SH, Nogales E, Bondy-Denomy J, Corn JE, Doudna JA.

Sci Adv. 2017 Jul 12;3(7):e1701620. doi: 10.1126/sciadv.1701620. eCollection 2017 Jul.

12.

Thigmotaxis Mediates Trail Odour Disruption.

Stringer LD, Corn JE, Sik Roh H, Jiménez-Pérez A, Manning LM, Harper AR, Suckling DM.

Sci Rep. 2017 May 10;7(1):1670. doi: 10.1038/s41598-017-01958-z.

13.

Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering.

Lee K, Mackley VA, Rao A, Chong AT, Dewitt MA, Corn JE, Murthy N.

Elife. 2017 May 2;6. pii: e25312. doi: 10.7554/eLife.25312.

14.

AJRCCM: 100-Year Anniversary. The History of Official American Thoracic Society Documents.

Wilson KC, Corn J.

Am J Respir Crit Care Med. 2017 May 1;195(9):1115-1117. doi: 10.1164/rccm.201703-0527ED. No abstract available.

PMID:
28459335
15.

Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.

Biel JT, Thompson MC, Cunningham CN, Corn JE, Fraser JS.

Structure. 2017 May 2;25(5):739-749.e3. doi: 10.1016/j.str.2017.03.009. Epub 2017 Apr 13.

16.

Genome editing via delivery of Cas9 ribonucleoprotein.

DeWitt MA, Corn JE, Carroll D.

Methods. 2017 May 15;121-122:9-15. doi: 10.1016/j.ymeth.2017.04.003. Epub 2017 Apr 12.

PMID:
28410976
17.

Amblyomma auricularium (Ixodida: Ixodidae) in Florida: New Hosts and Distribution Records.

Mertins JW, Vigil SL, Corn JL.

J Med Entomol. 2017 Jan;54(1):132-141. doi: 10.1093/jme/tjw159. Epub 2016 Oct 10.

PMID:
28082640
18.

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair.

Lee K, Conboy M, Park HM, Jiang F, Kim HJ, Dewitt MA, Mackley VA, Chang K, Rao A, Skinner C, Shobha T, Mehdipour M, Liu H, Huang WC, Lan F, Bray NL, Li S, Corn JE, Kataoka K, Doudna JA, Conboy I, Murthy N.

Nat Biomed Eng. 2017;1:889-901. doi: 10.1038/s41551-017-0137-2. Epub 2017 Oct 2.

19.

Cornerstones of CRISPR-Cas in drug discovery and therapy.

Fellmann C, Gowen BG, Lin PC, Doudna JA, Corn JE.

Nat Rev Drug Discov. 2017 Feb;16(2):89-100. doi: 10.1038/nrd.2016.238. Epub 2016 Dec 23. Review.

20.

Efficient production of bispecific IgG of different isotypes and species of origin in single mammalian cells.

Dillon M, Yin Y, Zhou J, McCarty L, Ellerman D, Slaga D, Junttila TT, Han G, Sandoval W, Ovacik MA, Lin K, Hu Z, Shen A, Corn JE, Spiess C, Carter PJ.

MAbs. 2017 Feb/Mar;9(2):213-230. doi: 10.1080/19420862.2016.1267089. Epub 2016 Dec 8.

21.

Vector species richness increases haemorrhagic disease prevalence through functional diversity modulating the duration of seasonal transmission - ERRATUM.

Park AW, Cleveland CA, Dallas TA, Corn JL.

Parasitology. 2016 Nov 29:1. [Epub ahead of print] No abstract available.

PMID:
27894363
22.

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.

Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS.

Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760.

23.

Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells.

DeWitt MA, Magis W, Bray NL, Wang T, Berman JR, Urbinati F, Heo SJ, Mitros T, Muñoz DP, Boffelli D, Kohn DB, Walters MC, Carroll D, Martin DI, Corn JE.

Sci Transl Med. 2016 Oct 12;8(360):360ra134.

24.

Non-homologous DNA increases gene disruption efficiency by altering DNA repair outcomes.

Richardson CD, Ray GJ, Bray NL, Corn JE.

Nat Commun. 2016 Aug 17;7:12463. doi: 10.1038/ncomms12463.

25.

Improving Health Literacy. The New American Thoracic Society Guidelines for Patient Education Materials.

Slatore CG, Kulkarni HS, Corn J, Sockrider M.

Ann Am Thorac Soc. 2016 Aug;13(8):1208-11. doi: 10.1513/AnnalsATS.201605-337OT. No abstract available.

26.

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.

Richardson CD, Ray GJ, DeWitt MA, Curie GL, Corn JE.

Nat Biotechnol. 2016 Mar;34(3):339-44. doi: 10.1038/nbt.3481. Epub 2016 Jan 20.

PMID:
26789497
27.

Using protein motion to read, write, and erase ubiquitin signals.

Phillips AH, Corn JE.

J Biol Chem. 2015 Oct 30;290(44):26437-44. doi: 10.1074/jbc.R115.653675. Epub 2015 Sep 9. Review.

28.

Vector species richness increases haemorrhagic disease prevalence through functional diversity modulating the duration of seasonal transmission.

Park AW, Cleveland CA, Dallas TA, Corn JL.

Parasitology. 2016 Jun;143(7):874-9. doi: 10.1017/S0031182015000578. Epub 2015 Jul 24.

PMID:
26206418
29.

Co-opting CRISPR to deliver functional RNAs.

Lin PC, Corn JE.

Nat Methods. 2015 Jul;12(7):613-4. doi: 10.1038/nmeth.3452. No abstract available.

PMID:
26125593
30.

CRISPR germline engineering--the community speaks.

Bosley KS, Botchan M, Bredenoord AL, Carroll D, Charo RA, Charpentier E, Cohen R, Corn J, Doudna J, Feng G, Greely HT, Isasi R, Ji W, Kim JS, Knoppers B, Lanphier E, Li J, Lovell-Badge R, Martin GS, Moreno J, Naldini L, Pera M, Perry AC, Venter JC, Zhang F, Zhou Q.

Nat Biotechnol. 2015 May;33(5):478-86. doi: 10.1038/nbt.3227. No abstract available.

PMID:
25965754
31.

Biotechnology. A prudent path forward for genomic engineering and germline gene modification.

Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR.

Science. 2015 Apr 3;348(6230):36-8. doi: 10.1126/science.aab1028. Epub 2015 Mar 19. No abstract available.

32.

USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria.

Cunningham CN, Baughman JM, Phu L, Tea JS, Yu C, Coons M, Kirkpatrick DS, Bingol B, Corn JE.

Nat Cell Biol. 2015 Feb;17(2):160-9. doi: 10.1038/ncb3097. Epub 2015 Jan 26.

PMID:
25621951
33.

Ubiquitin in inflammation: the right linkage makes all the difference.

Corn JE, Vucic D.

Nat Struct Mol Biol. 2014 Apr;21(4):297-300. doi: 10.1038/nsmb.2808. Review. No abstract available.

PMID:
24699077
34.

Persistence of Mycobacterium avium subspecies paratuberculosis in endangered Florida Key deer and Key deer habitat.

Murray HL, Yabsley MJ, Keel MK, Manning EJ, Wilmers TJ, Corn JL.

J Wildl Dis. 2014 Apr;50(2):349-53. doi: 10.7589/2013-04-081. Epub 2014 Feb 7.

PMID:
24506424
35.

Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.

Mukund S, Shang Y, Clarke HJ, Madjidi A, Corn JE, Kates L, Kolumam G, Chiang V, Luis E, Murray J, Zhang Y, Hötzel I, Koth CM, Allan BB.

J Biol Chem. 2013 Dec 13;288(50):36168-78. doi: 10.1074/jbc.M113.496984. Epub 2013 Nov 4.

36.

The RosettaCon 2012 Special Collection: Code Writ on Water, Documentation Writ in Stone.

André I, Corn J.

PLoS One. 2013 Sep 26;8(9):e73775. doi: 10.1371/journal.pone.0073775. eCollection 2013. No abstract available.

37.

Decoding a chain letter for degradation.

Cunningham CN, Corn JE.

Structure. 2013 Jul 2;21(7):1068-70. doi: 10.1016/j.str.2013.06.009.

38.

Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling.

Phillips AH, Zhang Y, Cunningham CN, Zhou L, Forrest WF, Liu PS, Steffek M, Lee J, Tam C, Helgason E, Murray JM, Kirkpatrick DS, Fairbrother WJ, Corn JE.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11379-84. doi: 10.1073/pnas.1302407110. Epub 2013 Jun 25.

39.

Feral swine brucellosis in the United States and prospective genomic techniques for disease epidemiology.

Leiser OP, Corn JL, Schmit BS, Keim PS, Foster JT.

Vet Microbiol. 2013 Sep 27;166(1-2):1-10. doi: 10.1016/j.vetmic.2013.02.025. Epub 2013 Mar 15. Review.

PMID:
23548760
40.

Stakeholder involvement: how to do it right: article 9 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report.

Cluzeau F, Wedzicha JA, Kelson M, Corn J, Kunz R, Walsh J, Schünemann HJ; ATS/ERS Ad Hoc Committee on Integrating and Coordinating Efforts in COPD Guideline Development.

Proc Am Thorac Soc. 2012 Dec;9(5):269-73. doi: 10.1513/pats.201208-062ST. Review.

PMID:
23256170
41.

Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7.

Zhang Y, Zhou L, Rouge L, Phillips AH, Lam C, Liu P, Sandoval W, Helgason E, Murray JM, Wertz IE, Corn JE.

Nat Chem Biol. 2013 Jan;9(1):51-8. doi: 10.1038/nchembio.1134. Epub 2012 Nov 25. Erratum in: Nat Chem Biol. 2013 Mar;9(3):192.

PMID:
23178935
42.

Aerosol delivery of trail pheromone disrupts the foraging of the red imported fire ant, Solenopsis invicta.

Suckling DM, Stringer LD, Corn JE, Bunn B, El-Sayed AM, Vander Meer RK.

Pest Manag Sci. 2012 Dec;68(12):1572-8. doi: 10.1002/ps.3349. Epub 2012 Jul 19.

PMID:
22815260
43.

Binding mechanism of metal⋅NTP substrates and stringent-response alarmones to bacterial DnaG-type primases.

Rymer RU, Solorio FA, Tehranchi AK, Chu C, Corn JE, Keck JL, Wang JD, Berger JM.

Structure. 2012 Sep 5;20(9):1478-89. doi: 10.1016/j.str.2012.05.017. Epub 2012 Jul 12.

44.

Outbreak of equine piroplasmosis in Florida.

Short MA, Clark CK, Harvey JW, Wenzlow N, Hawkins IK, Allred DR, Knowles DP, Corn JL, Grause JF, Hennager SG, Kitchen DL, Traub-Dargatz JL.

J Am Vet Med Assoc. 2012 Mar 1;240(5):588-95. doi: 10.2460/javma.240.5.588.

PMID:
22332629
45.

Lessons learned about collaborative evaluation using the Capacity for Applying Project Evaluation (CAPE) framework with school and district leaders.

Corn JO, Byrom E, Knestis K, Matzen N, Thrift B.

Eval Program Plann. 2012 Nov;35(4):535-42. doi: 10.1016/j.evalprogplan.2011.12.008. Epub 2012 Jan 3.

PMID:
22293532
46.

Community-wide assessment of protein-interface modeling suggests improvements to design methodology.

Fleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, Ko JS, Lee H, Seok C, Bourquard T, Bernauer J, Poupon A, Azé J, Soner S, Ovali SK, Ozbek P, Tal NB, Haliloglu T, Hwang H, Vreven T, Pierce BG, Weng Z, Pérez-Cano L, Pons C, Fernández-Recio J, Jiang F, Yang F, Gong X, Cao L, Xu X, Liu B, Wang P, Li C, Wang C, Robert CH, Guharoy M, Liu S, Huang Y, Li L, Guo D, Chen Y, Xiao Y, London N, Itzhaki Z, Schueler-Furman O, Inbar Y, Potapov V, Cohen M, Schreiber G, Tsuchiya Y, Kanamori E, Standley DM, Nakamura H, Kinoshita K, Driggers CM, Hall RG, Morgan JL, Hsu VL, Zhan J, Yang Y, Zhou Y, Kastritis PL, Bonvin AM, Zhang W, Camacho CJ, Kilambi KP, Sircar A, Gray JJ, Ohue M, Uchikoga N, Matsuzaki Y, Ishida T, Akiyama Y, Khashan R, Bush S, Fouches D, Tropsha A, Esquivel-Rodríguez J, Kihara D, Stranges PB, Jacak R, Kuhlman B, Huang SY, Zou X, Wodak SJ, Janin J, Baker D.

J Mol Biol. 2011 Nov 25;414(2):289-302. doi: 10.1016/j.jmb.2011.09.031. Epub 2011 Sep 29.

47.

Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United States.

Dong C, Meng J, Dai X, Liang JH, Feagins AR, Meng XJ, Belfiore NM, Bradford C, Corn JL, Cray C, Glass GE, Gordon ML, Hesse RA, Montgomery DL, Nicholson WL, Pilny AA, Ramamoorthy S, Shaver DD, Drobeniuc J, Purdy MA, Fields HA, Kamili S, Teo CG.

J Clin Microbiol. 2011 Dec;49(12):4164-72. doi: 10.1128/JCM.05481-11. Epub 2011 Oct 12.

48.

Argentine ant trail pheromone disruption is mediated by trail concentration.

Suckling DM, Stringer LD, Corn JE.

J Chem Ecol. 2011 Oct;37(10):1143-9. doi: 10.1007/s10886-011-0019-0. Epub 2011 Oct 1.

PMID:
21964852
49.

Hotspot-centric de novo design of protein binders.

Fleishman SJ, Corn JE, Strauch EM, Whitehead TA, Karanicolas J, Baker D.

J Mol Biol. 2011 Nov 11;413(5):1047-62. doi: 10.1016/j.jmb.2011.09.001. Epub 2011 Sep 10.

50.

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex.

Bentley ML, Corn JE, Dong KC, Phung Q, Cheung TK, Cochran AG.

EMBO J. 2011 Jul 19;30(16):3285-97. doi: 10.1038/emboj.2011.243.

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