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Items: 1 to 50 of 86

1.

An integrated experimental-computational approach for predicting virulence in New Zealand white rabbits and humans following inhalation exposure to Bacillus anthracis spores.

Hess BM, Thomas DG, Weber TJ, Hutchison JR, Straub TM, Bruckner-Lea CJ, Powell JD, Kabilan S, Corley RA.

PLoS One. 2019 Jul 1;14(7):e0219160. doi: 10.1371/journal.pone.0219160. eCollection 2019.

2.

Spatial distribution of marker gene activity in the mouse lung during alveolarization.

Ljungberg MC, Sadi M, Wang Y, Aronow BJ, Xu Y, Kao RJ, Liu Y, Gaddis N, Ardini-Poleske ME, Umrod T, Ambalavanan N, Nicola T, Kaminski N, Ahangari F, Sontag R, Corley RA, Ansong C, Carson JP.

Data Brief. 2018 Nov 3;22:365-372. doi: 10.1016/j.dib.2018.10.150. eCollection 2019 Feb.

3.

Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing.

Madeen E, Siddens LK, Uesugi S, McQuistan T, Corley RA, Smith J, Waters KM, Tilton SC, Anderson KA, Ognibene T, Turteltaub K, Williams DE.

Toxicol Appl Pharmacol. 2019 Feb 1;364:97-105. doi: 10.1016/j.taap.2018.12.010. Epub 2018 Dec 21.

PMID:
30582946
4.

Extracellular matrix in lung development, homeostasis and disease.

Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ.

Matrix Biol. 2018 Nov;73:77-104. doi: 10.1016/j.matbio.2018.03.005. Epub 2018 Mar 8. Review.

5.

Time-resolved proteome profiling of normal lung development.

Moghieb A, Clair G, Mitchell HD, Kitzmiller J, Zink EM, Kim YM, Petyuk V, Shukla A, Moore RJ, Metz TO, Carson J, McDermott JE, Corley RA, Whitsett JA, Ansong C.

Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L11-L24. doi: 10.1152/ajplung.00316.2017. Epub 2018 Mar 8.

6.

LungMAP: The Molecular Atlas of Lung Development Program.

Ardini-Poleske ME, Clark RF, Ansong C, Carson JP, Corley RA, Deutsch GH, Hagood JS, Kaminski N, Mariani TJ, Potter SS, Pryhuber GS, Warburton D, Whitsett JA, Palmer SM, Ambalavanan N; LungMAP Consortium.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L733-L740. doi: 10.1152/ajplung.00139.2017. Epub 2017 Aug 10. Review.

7.

Towards High-Resolution Tissue Imaging Using Nanospray Desorption Electrospray Ionization Mass Spectrometry Coupled to Shear Force Microscopy.

Nguyen SN, Sontag RL, Carson JP, Corley RA, Ansong C, Laskin J.

J Am Soc Mass Spectrom. 2018 Feb;29(2):316-322. doi: 10.1007/s13361-017-1750-8. Epub 2017 Jul 28.

8.

Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung.

Dautel SE, Kyle JE, Clair G, Sontag RL, Weitz KK, Shukla AK, Nguyen SN, Kim YM, Zink EM, Luders T, Frevert CW, Gharib SA, Laskin J, Carson JP, Metz TO, Corley RA, Ansong C.

Sci Rep. 2017 Feb 1;7:40555. doi: 10.1038/srep40555.

9.

In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes.

Smith JN, Mehinagic D, Nag S, Crowell SR, Corley RA.

Toxicol Lett. 2017 Mar 5;269:23-32. doi: 10.1016/j.toxlet.2017.01.008. Epub 2017 Jan 21.

PMID:
28119020
10.

Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol.

Shrivastava M, Lou S, Zelenyuk A, Easter RC, Corley RA, Thrall BD, Rasch PJ, Fast JD, Massey Simonich SL, Shen H, Tao S.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):1246-1251. doi: 10.1073/pnas.1618475114. Epub 2017 Jan 23. Erratum in: Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2263. Lou, Silja [corrected to Lou, Sijia].

11.

Spatially-Resolved Proteomics: Rapid Quantitative Analysis of Laser Capture Microdissected Alveolar Tissue Samples.

Clair G, Piehowski PD, Nicola T, Kitzmiller JA, Huang EL, Zink EM, Sontag RL, Orton DJ, Moore RJ, Carson JP, Smith RD, Whitsett JA, Corley RA, Ambalavanan N, Ansong C.

Sci Rep. 2016 Dec 22;6:39223. doi: 10.1038/srep39223.

12.

Expanding on Successful Concepts, Models, and Organization.

Teeguarden JG, Tan YM, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, L Massey Simonich S, Stone D, Tanguay RL, Waters KM, Harper SL, Williams DE.

Environ Sci Technol. 2016 Sep 6;50(17):8921-2. doi: 10.1021/acs.est.6b03027. Epub 2016 Aug 10. No abstract available.

PMID:
27509267
13.

Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry.

Madeen EP, Ognibene TJ, Corley RA, McQuistan TJ, Henderson MC, Baird WM, Bench G, Turteltaub KW, Williams DE.

Chem Res Toxicol. 2016 Oct 17;29(10):1641-1650. Epub 2016 Sep 9.

14.

Total and regional deposition of inhaled aerosols in supine healthy subjects and subjects with mild-to-moderate COPD.

Darquenne C, Lamm WJ, Fine JM, Corley RA, Glenny RW.

J Aerosol Sci. 2016 Sep;99:27-39. Epub 2016 Apr 30.

15.

Anatomical Details of the Rabbit Nasal Passages and Their Implications in Breathing, Air Conditioning, and Olfaction.

Xi J, Si XA, Kim J, Zhang Y, Jacob RE, Kabilan S, Corley RA.

Anat Rec (Hoboken). 2016 Jul;299(7):853-68. doi: 10.1002/ar.23367. Epub 2016 May 17.

16.

Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development.

Sadler NC, Nandhikonda P, Webb-Robertson BJ, Ansong C, Anderson LN, Smith JN, Corley RA, Wright AT.

Drug Metab Dispos. 2016 Jul;44(7):984-91. doi: 10.1124/dmd.115.068593. Epub 2016 Apr 15.

17.

Comparison of realistic and idealized breathing patterns in computational models of airflow and vapor dosimetry in the rodent upper respiratory tract.

Colby SM, Kabilan S, Jacob RE, Kuprat AP, Einstein DR, Corley RA.

Inhal Toxicol. 2016;28(4):192-202. doi: 10.3109/08958378.2016.1150367.

18.

Development of a Zealand white rabbit deposition model to study inhalation anthrax.

Asgharian B, Price O, Kabilan S, Jacob RE, Einstein DR, Kuprat AP, Corley RA.

Inhal Toxicol. 2016;28(2):80-8. doi: 10.3109/08958378.2016.1140850.

19.

Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework.

Teeguarden JG, Tan YM, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, Simonich SM, Stone D, Tanguay RL, Waters KM, Harper SL, Williams DE.

Environ Sci Technol. 2016 May 3;50(9):4579-86. doi: 10.1021/acs.est.5b05311. Epub 2016 Feb 10.

20.

Metabolite Signatures in Hydrophilic Extracts of Mouse Lungs Exposed to Cigarette Smoke Revealed by 1H NMR Metabolomics Investigation.

Jz H, X W, J F, Bj R, Km W, Sc T, Jg P, Ra C, M L, M H.

Metabolomics (Los Angel). 2015 Jun;5(2). pii: 143. Epub 2015 May 12.

21.

Comparative Risks of Aldehyde Constituents in Cigarette Smoke Using Transient Computational Fluid Dynamics/Physiologically Based Pharmacokinetic Models of the Rat and Human Respiratory Tracts.

Corley RA, Kabilan S, Kuprat AP, Carson JP, Jacob RE, Minard KR, Teeguarden JG, Timchalk C, Pipavath S, Glenny R, Einstein DR.

Toxicol Sci. 2015 Jul;146(1):65-88. doi: 10.1093/toxsci/kfv071. Epub 2015 Apr 8.

22.

CFD modeling and image analysis of exhaled aerosols due to a growing bronchial tumor: towards non-invasive diagnosis and treatment of respiratory obstructive diseases.

Xi J, Kim J, Si XA, Corley RA, Kabilan S, Wang S.

Theranostics. 2015 Feb 6;5(5):443-55. doi: 10.7150/thno.11107. eCollection 2015.

23.

Comparison of CT-derived ventilation maps with deposition patterns of inhaled microspheres in rats.

Jacob RE, Lamm WJ, Einstein DR, Krueger MA, Glenny RW, Corley RA.

Exp Lung Res. 2015 Apr;41(3):135-45. doi: 10.3109/01902148.2014.984085. Epub 2014 Dec 16.

24.

Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing.

Madeen E, Corley RA, Crowell S, Turteltaub K, Ognibene T, Malfatti M, McQuistan TJ, Garrard M, Sudakin D, Williams DE.

Chem Res Toxicol. 2015 Jan 20;28(1):126-34. doi: 10.1021/tx5003996. Epub 2014 Dec 10.

25.

Respiratory tract lung geometry and dosimetry model for male Sprague-Dawley rats.

Miller FJ, Asgharian B, Schroeter JD, Price O, Corley RA, Einstein DR, Jacob RE, Cox TC, Kabilan S, Bentley T.

Inhal Toxicol. 2014 Aug;26(9):524-44. doi: 10.3109/08958378.2014.925991.

PMID:
25055841
26.

In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes.

Crowell SR, Hanson-Drury S, Williams DE, Corley RA.

Toxicol Lett. 2014 Jul 3;228(1):48-55. doi: 10.1016/j.toxlet.2014.04.004. Epub 2014 Apr 21.

27.

A Bidirectional Coupling Procedure Applied to Multiscale Respiratory Modeling.

Kuprat AP, Kabilan S, Carson JP, Corley RA, Einstein DR.

J Comput Phys. 2013 Jul;244. doi: 10.1016/j.jcp.2012.10.021.

28.

Impaired transcriptional response of the murine heart to cigarette smoke in the setting of high fat diet and obesity.

Tilton SC, Karin NJ, Webb-Robertson BJ, Waters KM, Mikheev V, Lee KM, Corley RA, Pounds JG, Bigelow DJ.

Chem Res Toxicol. 2013 Jul 15;26(7):1034-42. doi: 10.1021/tx400078b. Epub 2013 Jun 20.

29.

Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice.

Crowell SR, Sharma AK, Amin S, Soelberg JJ, Sadler NC, Wright AT, Baird WM, Williams DE, Corley RA.

Toxicol Sci. 2013 Sep;135(1):48-62. doi: 10.1093/toxsci/kft124. Epub 2013 Jun 6.

30.

Diet-induced obesity reprograms the inflammatory response of the murine lung to inhaled endotoxin.

Tilton SC, Waters KM, Karin NJ, Webb-Robertson BJ, Zangar RC, Lee KM, Bigelow DJ, Pounds JG, Corley RA.

Toxicol Appl Pharmacol. 2013 Mar 1;267(2):137-48. doi: 10.1016/j.taap.2012.12.020. Epub 2013 Jan 7.

31.

An efficient algorithm for mapping imaging data to 3D unstructured grids in computational biomechanics.

Einstein DR, Kuprat AP, Jiao X, Carson JP, Einstein DM, Jacob RE, Corley RA.

Int J Numer Method Biomed Eng. 2013 Jan;29(1):1-16. doi: 10.1002/cnm.2489. Epub 2012 May 16.

32.

Oral Reference Dose for ethylene glycol based on oxalate crystal-induced renal tubule degeneration as the critical effect.

Snellings WM, Corley RA, McMartin KE, Kirman CR, Bobst SM.

Regul Toxicol Pharmacol. 2013 Mar;65(2):229-41. doi: 10.1016/j.yrtph.2012.12.005. Epub 2012 Dec 22.

PMID:
23266425
33.

Phase-contrast MRI and CFD modeling of apparent ³He gas flow in rat pulmonary airways.

Minard KR, Kuprat AP, Kabilan S, Jacob RE, Einstein DR, Carson JP, Corley RA.

J Magn Reson. 2012 Aug;221:129-38. doi: 10.1016/j.jmr.2012.05.007. Epub 2012 May 23.

34.

Comparative computational modeling of airflows and vapor dosimetry in the respiratory tracts of rat, monkey, and human.

Corley RA, Kabilan S, Kuprat AP, Carson JP, Minard KR, Jacob RE, Timchalk C, Glenny R, Pipavath S, Cox T, Wallis CD, Larson RF, Fanucchi MV, Postlethwait EM, Einstein DR.

Toxicol Sci. 2012 Aug;128(2):500-16. doi: 10.1093/toxsci/kfs168. Epub 2012 May 12.

35.

Branch-based model for the diameters of the pulmonary airways: accounting for departures from self-consistency and registration errors.

Neradilek MB, Polissar NL, Einstein DR, Glenny RW, Minard KR, Carson JP, Jiao X, Jacob RE, Cox TC, Postlethwait EM, Corley RA.

Anat Rec (Hoboken). 2012 Jun;295(6):1027-44. doi: 10.1002/ar.22476. Epub 2012 Apr 24.

36.

A multiscale bidirectional coupling framework.

Kabilan S, Kuprat AP, Hlastala MP, Corley RA, Einstein DR.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:2414-7. doi: 10.1109/IEMBS.2011.6090672.

PMID:
22254828
37.

Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring.

Shorey LE, Castro DJ, Baird WM, Siddens LK, Löhr CV, Matzke MM, Waters KM, Corley RA, Williams DE.

Cancer Lett. 2012 Apr 1;317(1):49-55. doi: 10.1016/j.canlet.2011.11.010. Epub 2011 Nov 13.

38.

Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents.

Crowell SR, Amin SG, Anderson KA, Krishnegowda G, Sharma AK, Soelberg JJ, Williams DE, Corley RA.

Toxicol Appl Pharmacol. 2011 Dec 15;257(3):365-76. doi: 10.1016/j.taap.2011.09.020. Epub 2011 Sep 29.

39.

Extension of a PBPK model for ethylene glycol and glycolic acid to include the competitive formation and clearance of metabolites associated with kidney toxicity in rats and humans.

Corley RA, Saghir SA, Bartels MJ, Hansen SC, Creim J, McMartin KE, Snellings WM.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):229-44. doi: 10.1016/j.taap.2010.10.011. Epub 2010 Nov 11.

PMID:
21074520
40.

The impact of dose rate on ethylene glycol developmental toxicity and pharmacokinetics in pregnant CD rats.

Carney EW, Tornesi B, Liberacki AB, Markham DA, Weitz KK, Luders TM, Studniski KG, Blessing JC, Gies RA, Corley RA.

Toxicol Sci. 2011 Jan;119(1):178-88. doi: 10.1093/toxsci/kfq310. Epub 2010 Oct 15.

PMID:
20952502
41.

High resolution lung airway cast segmentation with proper topology suitable for computational fluid dynamic simulations.

Carson JP, Einstein DR, Minard KR, Fanucchi MV, Wallis CD, Corley RA.

Comput Med Imaging Graph. 2010 Oct;34(7):572-8. doi: 10.1016/j.compmedimag.2010.03.001. Epub 2010 Apr 10.

42.

A real-time methodology to evaluate the nasal absorption of volatile compounds in anesthetized animals.

Thrall KD, Woodstock AD, Soelberg JJ, Gargas ML, Kinzell JH, Corley RA.

Inhal Toxicol. 2009 May;21(6):531-6. doi: 10.1080/08958370802601452.

PMID:
19519153
43.

In vitro glutathione conjugation of methyl iodide in rat, rabbit, and human blood and tissues.

Poet TS, Wu H, Corley RA, Thrall KD.

Inhal Toxicol. 2009 May;21(6):524-30. doi: 10.1080/08958370802598203.

PMID:
19519152
44.

Magnetic resonance imaging and computational fluid dynamics (CFD) simulations of rabbit nasal airflows for the development of hybrid CFD/PBPK models.

Corley RA, Minard KR, Kabilan S, Einstein DR, Kuprat AP, Harkema JR, Kimbell JS, Gargas ML, Kinzell JH.

Inhal Toxicol. 2009 May;21(6):512-8. doi: 10.1080/08958370802598005.

45.

Studies supporting the development of a physiologically based pharmacokinetic (PBPK) model for methyl iodide: pharmacokinetics of sodium iodide (NaI) in pregnant rabbits.

Thrall KD, Sasser LB, Creim JA, Gargas ML, Kinzell JH, Corley RA.

Inhal Toxicol. 2009 May;21(6):519-23. doi: 10.1080/08958370802598286.

PMID:
19337875
46.

An automated self-similarity analysis of the pulmonary tree of the Sprague-Dawley rat.

Einstein DR, Neradilak B, Pollisar N, Minard KR, Wallis C, Fanucchi M, Carson JP, Kuprat AP, Kabilan S, Jacob RE, Corley RA.

Anat Rec (Hoboken). 2008 Dec;291(12):1628-48. doi: 10.1002/ar.20771.

47.

MR imaging of apparent 3He gas transport in narrow pipes and rodent airways.

Minard KR, Jacob RE, Laicher G, Einstein DR, Kuprat AP, Corley RA.

J Magn Reson. 2008 Oct;194(2):182-91. doi: 10.1016/j.jmr.2008.07.006. Epub 2008 Jul 13.

48.

Dosimetry considerations in the enhanced sensitivity of male Wistar rats to chronic ethylene glycol-induced nephrotoxicity.

Corley RA, Wilson DM, Hard GC, Stebbins KE, Bartels MJ, Soelberg JJ, Dryzga MD, Gingell R, McMartin KE, Snellings WM.

Toxicol Appl Pharmacol. 2008 Apr 15;228(2):165-78. doi: 10.1016/j.taap.2007.11.024. Epub 2007 Dec 4.

PMID:
18191429
49.

Physiologically based pharmacokinetic modeling of the disposition of octamethylcyclotetrasiloxane (D4) migration from implants in humans.

Thrall KD, Soelberg JJ, Powell T, Corley RA.

J Long Term Eff Med Implants. 2008;18(2):133-44.

PMID:
19968622
50.

Physiologically based pharmacokinetic modeling of 1,4-Dioxane in rats, mice, and humans.

Sweeney LM, Thrall KD, Poet TS, Corley RA, Weber TJ, Locey BJ, Clarkson J, Sager S, Gargas ML.

Toxicol Sci. 2008 Jan;101(1):32-50. Epub 2007 Sep 25.

PMID:
17897969

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