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Items: 18


A mass spectrometry-based approach to distinguish annular and specific lipid binding to membrane proteins.

Bolla JR, Corey RA, Sahin C, Gault J, Hummer A, Hopper JTS, Lane DP, Drew D, Allison TM, Stansfeld PJ, Robinson CV, Landreh M.

Angew Chem Int Ed Engl. 2019 Dec 30. doi: 10.1002/anie.201914411. [Epub ahead of print]


The energetics of protein-lipid interactions as viewed by molecular simulations.

Corey RA, Stansfeld PJ, Sansom MSP.

Biochem Soc Trans. 2019 Dec 24. pii: BST20190149. doi: 10.1042/BST20190149. [Epub ahead of print]


Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2.

Wang Q, Corey RA, Hedger G, Aryal P, Grieben M, Nasrallah C, Baronina A, Pike ACW, Shi J, Carpenter EP, Sansom MSP.

Structure. 2019 Nov 27. pii: S0969-2126(19)30389-2. doi: 10.1016/j.str.2019.11.005. [Epub ahead of print]


Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer.

Parker JL, Corey RA, Stansfeld PJ, Newstead S.

Nat Commun. 2019 Oct 11;10(1):4657. doi: 10.1038/s41467-019-12673-w.


The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.

Bushell SR, Pike ACW, Falzone ME, Rorsman NJG, Ta CM, Corey RA, Newport TD, Christianson JC, Scofano LF, Shintre CA, Tessitore A, Chu A, Wang Q, Shrestha L, Mukhopadhyay SMM, Love JD, Burgess-Brown NA, Sitsapesan R, Stansfeld PJ, Huiskonen JT, Tammaro P, Accardi A, Carpenter EP.

Nat Commun. 2019 Sep 2;10(1):3956. doi: 10.1038/s41467-019-11753-1.


Insights into Membrane Protein-Lipid Interactions from Free Energy Calculations.

Corey RA, Vickery ON, Sansom MSP, Stansfeld PJ.

J Chem Theory Comput. 2019 Oct 8;15(10):5727-5736. doi: 10.1021/acs.jctc.9b00548. Epub 2019 Sep 17.


HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon.

Ahdash Z, Pyle E, Allen WJ, Corey RA, Collinson I, Politis A.

Elife. 2019 Jul 10;8. pii: e47402. doi: 10.7554/eLife.47402.


Structure and Dynamics of the Central Lipid Pool and Proteins of the Bacterial Holo-Translocon.

Martin R, Larsen AH, Corey RA, Midtgaard SR, Frielinghaus H, Schaffitzel C, Arleth L, Collinson I.

Biophys J. 2019 May 21;116(10):1931-1940. doi: 10.1016/j.bpj.2019.04.002. Epub 2019 Apr 9.


A lipid gating mechanism for the channel-forming O antigen ABC transporter.

Caffalette CA, Corey RA, Sansom MSP, Stansfeld PJ, Zimmer J.

Nat Commun. 2019 Feb 18;10(1):824. doi: 10.1038/s41467-019-08646-8.


ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery.

Corey RA, Ahdash Z, Shah A, Pyle E, Allen WJ, Fessl T, Lovett JE, Politis A, Collinson I.

Elife. 2019 Jan 2;8. pii: e41803. doi: 10.7554/eLife.41803.


Specific cardiolipin-SecY interactions are required for proton-motive force stimulation of protein secretion.

Corey RA, Pyle E, Allen WJ, Watkins DW, Casiraghi M, Miroux B, Arechaga I, Politis A, Collinson I.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):7967-7972. doi: 10.1073/pnas.1721536115. Epub 2018 Jul 16.


Dynamic action of the Sec machinery during initiation, protein translocation and termination.

Fessl T, Watkins D, Oatley P, Allen WJ, Corey RA, Horne J, Baldwin SA, Radford SE, Collinson I, Tuma R.

Elife. 2018 Jun 7;7. pii: e35112. doi: 10.7554/eLife.35112.


Composition and Activity of the Non-canonical Gram-positive SecY2 Complex.

Bandara M, Corey RA, Martin R, Skehel JM, Blocker AJ, Jenkinson HF, Collinson I.

J Biol Chem. 2016 Oct 7;291(41):21474-21484. Epub 2016 Aug 22.


Protein translocation: what's the problem?

Corey RA, Allen WJ, Collinson I.

Biochem Soc Trans. 2016 Jun 15;44(3):753-9. doi: 10.1042/BST20160047. Review.


Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation.

Allen WJ, Corey RA, Oatley P, Sessions RB, Baldwin SA, Radford SE, Tuma R, Collinson I.

Elife. 2016 May 16;5. pii: e15598. doi: 10.7554/eLife.15598.


Unlocking the Bacterial SecY Translocon.

Corey RA, Allen WJ, Komar J, Masiulis S, Menzies S, Robson A, Collinson I.

Structure. 2016 Apr 5;24(4):518-527. doi: 10.1016/j.str.2016.02.001. Epub 2016 Mar 10.


Channel crossing: how are proteins shipped across the bacterial plasma membrane?

Collinson I, Corey RA, Allen WJ.

Philos Trans R Soc Lond B Biol Sci. 2015 Oct 5;370(1679). pii: 20150025. doi: 10.1098/rstb.2015.0025. Review.


Diethyl 2-chlorovinyl phosphate and dimethyl 1-carbomethoxy-1-propen-2-yl phosphate, two new systemic phosphorus pesticides.


Science. 1953 Jul 3;118(3053):28-9. No abstract available.


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