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Items: 1 to 50 of 422

1.

Delivery of Antisense Oligonucleotides to the Cornea.

Chau VQ, Hu J, Gong X, Hulleman JD, Ufret-Vincenty RL, Rigo F, Prakash TP, Corey DR, Mootha VV.

Nucleic Acid Ther. 2020 Mar 23. doi: 10.1089/nat.2019.0838. [Epub ahead of print]

PMID:
32202944
2.

Viral vectors for gene delivery to the inner ear.

Maguire CA, Corey DP.

Hear Res. 2020 Feb 23:107927. doi: 10.1016/j.heares.2020.107927. [Epub ahead of print] Review.

PMID:
32199720
3.

Preclinical testing of AAV9-PHP.B for transgene expression in the non-human primate cochlea.

Ivanchenko MV, Hanlon KS, Devine MK, Tenneson K, Emond F, Lafond JF, Kenna MA, Corey DP, Maguire CA.

Hear Res. 2020 Feb 26:107930. doi: 10.1016/j.heares.2020.107930. [Epub ahead of print]

PMID:
32145977
4.

The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy.

Aartsma-Rus A, Corey DR.

Nucleic Acid Ther. 2020 Apr;30(2):67-70. doi: 10.1089/nat.2020.0845. Epub 2020 Feb 11. No abstract available.

PMID:
32043902
5.

Examining the Validity of the Multidimensional Personality Questionnaire in the Assessment of Police Candidates.

Sellbom M, Corey DM, Ben-Porath YS.

Assessment. 2019 Nov 13:1073191119887443. doi: 10.1177/1073191119887443. [Epub ahead of print]

PMID:
31718241
6.

Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.

Liu Z, Johnson ST, Zhang Z, Corey DR.

Nucleic Acid Ther. 2019 Dec;29(6):323-334. doi: 10.1089/nat.2019.0815. Epub 2019 Oct 31.

7.

Limits of using oligonucleotides for allele-selective inhibition at trinucleotide repeat sequences - targeting the CAG repeat within ataxin-1.

Hu J, Corey DR.

Nucleosides Nucleotides Nucleic Acids. 2019 Oct 24:1-10. doi: 10.1080/15257770.2019.1671592. [Epub ahead of print]

PMID:
31645175
8.

High levels of AAV vector integration into CRISPR-induced DNA breaks.

Hanlon KS, Kleinstiver BP, Garcia SP, Zaborowski MP, Volak A, Spirig SE, Muller A, Sousa AA, Tsai SQ, Bengtsson NE, Lööv C, Ingelsson M, Chamberlain JS, Corey DP, Aryee MJ, Joung JK, Breakefield XO, Maguire CA, György B.

Nat Commun. 2019 Sep 30;10(1):4439. doi: 10.1038/s41467-019-12449-2.

9.

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy.

Rong Z, Hu J, Corey DR, Mootha VV.

Invest Ophthalmol Vis Sci. 2019 Sep 3;60(12):3980-3991. doi: 10.1167/iovs.19-27641.

10.

PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing.

Wu X, Ivanchenko MV, Al Jandal H, Cicconet M, Indzhykulian AA, Corey DP.

Nat Commun. 2019 Aug 23;10(1):3801. doi: 10.1038/s41467-019-11712-w.

11.

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss.

György B, Nist-Lund C, Pan B, Asai Y, Karavitaki KD, Kleinstiver BP, Garcia SP, Zaborowski MP, Solanes P, Spataro S, Schneider BL, Joung JK, Géléoc GSG, Holt JR, Corey DP.

Nat Med. 2019 Jul;25(7):1123-1130. doi: 10.1038/s41591-019-0500-9. Epub 2019 Jul 3.

12.

Efficient electroporation of neuronal cells using synthetic oligonucleotides: identifying duplex RNA and antisense oligonucleotide activators of human frataxin expression.

Shen X, Beasley S, Putman JN, Li Y, Prakash TP, Rigo F, Napierala M, Corey DR.

RNA. 2019 Sep;25(9):1118-1129. doi: 10.1261/rna.071290.119. Epub 2019 May 31.

13.

Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs.

Gagnon KT, Corey DR.

Nucleic Acid Ther. 2019 Jun;29(3):116-122. doi: 10.1089/nat.2018.0772. Epub 2019 Mar 23.

14.

Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells.

Rymut SM, Lu B, Perez A, Corey DA, Lamb K, Cotton CU, Kelley TJ.

Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1081-L1093. doi: 10.1152/ajplung.00369.2018. Epub 2019 Mar 20.

PMID:
30892081
15.

Duplex RNAs and ss-siRNAs Block RNA Foci Associated with Fuchs' Endothelial Corneal Dystrophy.

Hu J, Shen X, Rigo F, Prakash TP, Mootha VV, Corey DR.

Nucleic Acid Ther. 2019 Apr;29(2):73-81. doi: 10.1089/nat.2018.0764. Epub 2019 Jan 24.

16.

Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate.

György B, Meijer EJ, Ivanchenko MV, Tenneson K, Emond F, Hanlon KS, Indzhykulian AA, Volak A, Karavitaki KD, Tamvakologos PI, Vezina M, Berezovskii VK, Born RT, O'Brien M, Lafond JF, Arsenijevic Y, Kenna MA, Maguire CA, Corey DP.

Mol Ther Methods Clin Dev. 2018 Nov 20;13:1-13. doi: 10.1016/j.omtm.2018.11.003. eCollection 2019 Jun 14.

17.

Complex mammalian-like haematopoietic system found in a colonial chordate.

Rosental B, Kowarsky M, Seita J, Corey DM, Ishizuka KJ, Palmeri KJ, Chen SY, Sinha R, Okamoto J, Mantalas G, Manni L, Raveh T, Clarke DN, Tsai JM, Newman AM, Neff NF, Nolan GP, Quake SR, Weissman IL, Voskoboynik A.

Nature. 2018 Dec;564(7736):425-429. doi: 10.1038/s41586-018-0783-x. Epub 2018 Dec 5.

18.

Function and Dysfunction of TMC Channels in Inner Ear Hair Cells.

Corey DP, Akyuz N, Holt JR.

Cold Spring Harb Perspect Med. 2019 Oct 1;9(10). pii: a033506. doi: 10.1101/cshperspect.a033506. Review.

19.

TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells.

Pan B, Akyuz N, Liu XP, Asai Y, Nist-Lund C, Kurima K, Derfler BH, György B, Limapichat W, Walujkar S, Wimalasena LN, Sotomayor M, Corey DP, Holt JR.

Neuron. 2018 Aug 22;99(4):736-753.e6. doi: 10.1016/j.neuron.2018.07.033.

20.

The Requirement for GW182 Scaffolding Protein Depends on Whether Argonaute Is Mediating Translation, Transcription, or Splicing.

Liu J, Liu Z, Corey DR.

Biochemistry. 2018 Sep 4;57(35):5247-5256. doi: 10.1021/acs.biochem.8b00602. Epub 2018 Aug 21.

21.

Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion.

Shen X, Kilikevicius A, O'Reilly D, Prakash TP, Damha MJ, Rigo F, Corey DR.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2850-2855. doi: 10.1016/j.bmcl.2018.07.033. Epub 2018 Jul 21.

22.

Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells.

Krey JF, Scheffer DI, Choi D, Reddy A, David LL, Corey DP, Barr-Gillespie PG.

Sci Data. 2018 Jul 17;5:180128. doi: 10.1038/sdata.2018.128.

23.

Risks associated with overcontrolled behavior in police officer recruits.

Corey DM, Sellbom M, Ben-Porath YS.

Psychol Assess. 2018 Dec;30(12):1691-1702. doi: 10.1037/pas0000607. Epub 2018 Jun 11.

PMID:
29888947
24.

Editorial: Nucleic Acids Research and Nucleic Acid Therapeutics.

Stoddard BL, Khvorova A, Corey DR, Dynan WS, Fox KR.

Nucleic Acids Res. 2018 Feb 28;46(4):1563-1564. doi: 10.1093/nar/gky059. No abstract available.

25.

Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat.

Li L, Shen X, Liu Z, Norrbom M, Prakash TP, O'Reilly D, Sharma VK, Damha MJ, Watts JK, Rigo F, Corey DR.

Nucleic Acid Ther. 2018 Feb;28(1):23-33. doi: 10.1089/nat.2017.0703. Epub 2018 Jan 17.

26.

Oligonucleotides targeting TCF4 triplet repeat expansion inhibit RNA foci and mis-splicing in Fuchs' dystrophy.

Hu J, Rong Z, Gong X, Zhou Z, Sharma VK, Xing C, Watts JK, Corey DR, Mootha VV.

Hum Mol Genet. 2018 Mar 15;27(6):1015-1026. doi: 10.1093/hmg/ddy018.

27.

Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs.

Shen X, Corey DR.

Nucleic Acids Res. 2018 Feb 28;46(4):1584-1600. doi: 10.1093/nar/gkx1239. Review.

28.

Association of built environment characteristics with adiposity and glycaemic measures.

Lee JJ, Hwang SJ, Mutalik K, Corey D, Joyce R, Block JP, Fox CS, Powell-Wiley TM.

Obes Sci Pract. 2017 Jul 11;3(3):333-341. doi: 10.1002/osp4.115. eCollection 2017 Sep.

29.

Heterodimeric capping protein is required for stereocilia length and width regulation.

Avenarius MR, Krey JF, Dumont RA, Morgan CP, Benson CB, Vijayakumar S, Cunningham CL, Scheffer DI, Corey DP, Müller U, Jones SM, Barr-Gillespie PG.

J Cell Biol. 2017 Nov 6;216(11):3861-3881. doi: 10.1083/jcb.201704171. Epub 2017 Sep 12.

30.

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

Hicks JA, Li L, Matsui M, Chu Y, Volkov O, Johnson KC, Corey DR.

Cell Rep. 2017 Aug 15;20(7):1543-1552. doi: 10.1016/j.celrep.2017.07.058.

31.

Pathways in the Degradation of Geminal Diazides.

Holzschneider K, Häring AP, Haack A, Corey DJ, Benter T, Kirsch SF.

J Org Chem. 2017 Aug 4;82(15):8242-8250. doi: 10.1021/acs.joc.7b01019. Epub 2017 Jul 19.

PMID:
28722411
32.

RNA-Mediated Gene Activation: Identifying a Candidate RNA for Preclinical Development.

Corey DR.

Adv Exp Med Biol. 2017;983:161-171. doi: 10.1007/978-981-10-4310-9_11.

PMID:
28639198
33.

Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6.

Rymut SM, Corey DA, Valerio DM, Erokwu BO, Flask CA, Kelley TJ, Hodges CA.

Sci Rep. 2017 Jun 16;7(1):3676. doi: 10.1038/s41598-017-03931-2.

34.

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

Gordon SR, Maute RL, Dulken BW, Hutter G, George BM, McCracken MN, Gupta R, Tsai JM, Sinha R, Corey D, Ring AM, Connolly AJ, Weissman IL.

Nature. 2017 May 25;545(7655):495-499. doi: 10.1038/nature22396. Epub 2017 May 17.

35.

Nusinersen, an antisense oligonucleotide drug for spinal muscular atrophy.

Corey DR.

Nat Neurosci. 2017 Apr;20(4):497-499. doi: 10.1038/nn.4508. Epub 2017 Feb 13. Review. No abstract available.

PMID:
28192393
36.

c9orf72 Disease-Related Foci Are Each Composed of One Mutant Expanded Repeat RNA.

Liu J, Hu J, Ludlow AT, Pham JT, Shay JW, Rothstein JD, Corey DR.

Cell Chem Biol. 2017 Feb 16;24(2):141-148. doi: 10.1016/j.chembiol.2016.12.018. Epub 2017 Jan 26.

37.

Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.

György B, Sage C, Indzhykulian AA, Scheffer DI, Brisson AR, Tan S, Wu X, Volak A, Mu D, Tamvakologos PI, Li Y, Fitzpatrick Z, Ericsson M, Breakefield XO, Corey DP, Maguire CA.

Mol Ther. 2017 Feb 1;25(2):379-391. doi: 10.1016/j.ymthe.2016.12.010. Epub 2017 Jan 9.

38.

Recognition of c9orf72 Mutant RNA by Single-Stranded Silencing RNAs.

Hu J, Rigo F, Prakash TP, Corey DR.

Nucleic Acid Ther. 2017 Apr;27(2):87-94. doi: 10.1089/nat.2016.0655. Epub 2016 Dec 22.

39.

Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo.

Rivera-Monroy J, Musiol L, Unthan-Fechner K, Farkas Á, Clancy A, Coy-Vergara J, Weill U, Gockel S, Lin SY, Corey DP, Kohl T, Ströbel P, Schuldiner M, Schwappach B, Vilardi F.

Sci Rep. 2016 Dec 21;6:39464. doi: 10.1038/srep39464.

40.

The Outer Pore and Selectivity Filter of TRPA1.

Christensen AP, Akyuz N, Corey DP.

PLoS One. 2016 Nov 8;11(11):e0166167. doi: 10.1371/journal.pone.0166167. eCollection 2016.

41.

Non-coding RNAs as drug targets.

Matsui M, Corey DR.

Nat Rev Drug Discov. 2017 Mar;16(3):167-179. doi: 10.1038/nrd.2016.117. Epub 2016 Jul 22. Review.

42.

Doubts About Therapy for Neurological Diseases With Antisense Oligonucleotides-Reply.

Corey DR.

JAMA Neurol. 2016 Dec 1;73(12):1502-1503. doi: 10.1001/jamaneurol.2016.4335. No abstract available.

PMID:
27802484
43.

Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?

Corey DP, Holt JR.

J Neurosci. 2016 Oct 26;36(43):10921-10926.

44.

From Biological Cilia to Artificial Flow Sensors: Biomimetic Soft Polymer Nanosensors with High Sensing Performance.

Asadnia M, Kottapalli AG, Karavitaki KD, Warkiani ME, Miao J, Corey DP, Triantafyllou M.

Sci Rep. 2016 Sep 13;6:32955. doi: 10.1038/srep32955.

45.

Synthetic Nucleic Acids and Treatment of Neurological Diseases.

Corey DR.

JAMA Neurol. 2016 Oct 1;73(10):1238-1242. doi: 10.1001/jamaneurol.2016.2089. Review.

PMID:
27479447
46.

Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.

Vogl C, Panou I, Yamanbaeva G, Wichmann C, Mangosing SJ, Vilardi F, Indzhykulian AA, Pangršič T, Santarelli R, Rodriguez-Ballesteros M, Weber T, Jung S, Cardenas E, Wu X, Wojcik SM, Kwan KY, Del Castillo I, Schwappach B, Strenzke N, Corey DP, Lin SY, Moser T.

EMBO J. 2016 Dec 1;35(23):2536-2552. Epub 2016 Jul 25.

47.

HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.

Liu H, Liang C, Kollipara RK, Matsui M, Ke X, Jeong BC, Wang Z, Yoo KS, Yadav GP, Kinch LN, Grishin NV, Nam Y, Corey DR, Kittler R, Liu Q.

Mol Cell. 2016 Aug 4;63(3):420-32. doi: 10.1016/j.molcel.2016.06.014. Epub 2016 Jul 14.

48.

Behavioural and neurophysiological disruption of corticobulbar motor systems and their effects on sequential pharyngeal swallowing.

Al-Toubi A, Daniels SK, Huckabee ML, Corey DM, Doeltgen SH.

Physiol Behav. 2016 Oct 15;165:69-76. doi: 10.1016/j.physbeh.2016.06.039. Epub 2016 Jul 1.

PMID:
27378508
49.

Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells.

Rymut SM, Kampman CM, Corey DA, Endres T, Cotton CU, Kelley TJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L317-27. doi: 10.1152/ajplung.00126.2016. Epub 2016 Jun 17.

50.

Developmental cell death programs license cytotoxic cells to eliminate histocompatible partners.

Corey DM, Rosental B, Kowarsky M, Sinha R, Ishizuka KJ, Palmeri KJ, Quake SR, Voskoboynik A, Weissman IL.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6520-5. doi: 10.1073/pnas.1606276113. Epub 2016 May 23.

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