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Items: 18

1.

Synthesis, antiviral activity and pharmacokinetics of P1/P1' substituted 3-aminoindazole cyclic urea HIV protease inhibitors.

Kaltenbach RF 3rd, Patel M, Waltermire RE, Harris GD, Stone BR, Klabe RM, Garber S, Bacheler LT, Cordova BC, Logue K, Wright MR, Erickson-Viitanen S, Trainor GL.

Bioorg Med Chem Lett. 2003 Feb 24;13(4):605-8.

PMID:
12639540
2.

Synthesis and evaluation of novel quinolinones as HIV-1 reverse transcriptase inhibitors.

Patel M, McHugh RJ Jr, Cordova BC, Klabe RM, Bacheler LT, Erickson-Viitanen S, Rodgers JD.

Bioorg Med Chem Lett. 2001 Jul 23;11(14):1943-5.

PMID:
11459666
3.

4,1-Benzoxazepinone analogues of efavirenz (Sustiva) as HIV-1 reverse transcriptase inhibitors.

Cocuzza AJ, Chidester DR, Cordova BC, Klabe RM, Jeffrey S, Diamond S, Weigelt CA, Ko SS, Bacheler LT, Erickson-Viitanen SK, Rodgers JD.

Bioorg Med Chem Lett. 2001 Jun 4;11(11):1389-92.

PMID:
11378361
4.

Synthesis and evaluation of efavirenz (Sustiva) analogues as HIV-1 reverse transcriptase inhibitors: replacement of the cyclopropylacetylene side chain.

Cocuzza AJ, Chidester DR, Cordova BC, Jeffrey S, Parsons RL, Bacheler LT, Erickson-Viitanen S, Trainor GL, Ko SS.

Bioorg Med Chem Lett. 2001 May 7;11(9):1177-9.

PMID:
11354371
5.

Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor efavirenz.

Markwalder JA, Christ DD, Mutlib A, Cordova BC, Klabe RM, Seitz SP.

Bioorg Med Chem Lett. 2001 Mar 12;11(5):619-22.

PMID:
11266155
6.

Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase.

Corbett JW, Kresge KJ, Pan S, Cordova BC, Klabe RM, Rodgers JD, Erickson-Viitanen SK.

Bioorg Med Chem Lett. 2001 Feb 12;11(3):309-12.

PMID:
11212098
7.

3,3a-Dihydropyrano[4,3,2-de]quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors.

Corbett JW, Pan S, Markwalder JA, Cordova BC, Klabe RM, Garber S, Rodgers JD, Erickson-Viitanen SK.

Bioorg Med Chem Lett. 2001 Jan 22;11(2):211-4.

PMID:
11206461
8.

Synthesis and evaluation of quinoxalinones as HIV-1 reverse transcriptase inhibitors.

Patel M, McHugh RJ Jr, Cordova BC, Klabe RM, Erickson-Viitanen S, Trainor GL, Rodgers JD.

Bioorg Med Chem Lett. 2000 Aug 7;10(15):1729-31.

PMID:
10937734
9.

Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors.

Corbett JW, Ko SS, Rodgers JD, Gearhart LA, Magnus NA, Bacheler LT, Diamond S, Jeffrey S, Klabe RM, Cordova BC, Garber S, Logue K, Trainor GL, Anderson PS, Erickson-Viitanen SK.

J Med Chem. 2000 May 18;43(10):2019-30.

PMID:
10821714
10.

Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors.

Corbett JW, Gearhart LA, Ko SS, Rodgers JD, Cordova BC, Klabe RM, Erickson-Viitanen SK.

Bioorg Med Chem Lett. 2000 Jan 17;10(2):193-5.

PMID:
10673109
11.

Synthesis and evaluation of benzoxazinones as HIV-1 reverse transcriptase inhibitors. Analogs of Efavirenz (SUSTIVA).

Patel M, McHugh RJ Jr, Cordova BC, Klabe RM, Erickson-Viitanen S, Trainor GL, Ko SS.

Bioorg Med Chem Lett. 1999 Nov 15;9(22):3221-4.

PMID:
10576692
12.

Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: novel biaryl indazoles as P2/P2' substituents.

Patel M, Rodgers JD, McHugh RJ Jr, Johnson BL, Cordova BC, Klabe RM, Bacheler LT, Erickson-Viitanen S, Ko SS.

Bioorg Med Chem Lett. 1999 Nov 15;9(22):3217-20.

PMID:
10576691
13.

Synthesis and evaluation of analogs of Efavirenz (SUSTIVA) as HIV-1 reverse transcriptase inhibitors.

Patel M, Ko SS, McHugh RJ Jr, Markwalder JA, Srivastava AS, Cordova BC, Klabe RM, Erickson-Viitanen S, Trainor GL, Seitz SP.

Bioorg Med Chem Lett. 1999 Oct 4;9(19):2805-10.

PMID:
10522695
14.

Increased antiviral activity of cyclic urea HIV protease inhibitors by modifying the P1/P1' substituents.

Kaltenbach RF 3rd, Klabe RM, Cordova BC, Seitz SP.

Bioorg Med Chem Lett. 1999 Aug 2;9(15):2259-62.

PMID:
10465557
15.

The synthesis of symmetrical and unsymmetrical P1/P1' cyclic ureas as HIV protease inhibitors.

Patel M, Kaltenbach RF 3rd, Nugiel DA, McHugh RJ Jr, Jadhav PK, Bacheler LT, Cordova BC, Klabe RM, Erickson-Viitanen S, Garber S, Reid C, Seitz SP.

Bioorg Med Chem Lett. 1998 May 5;8(9):1077-82.

PMID:
9871711
16.

The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: modifications of the P1/P1' residues.

Patel M, Bacheler LT, Rayner MM, Cordova BC, Klabe RM, Erickson-Viitanen S, Seitz SP.

Bioorg Med Chem Lett. 1998 Apr 7;8(7):823-8.

PMID:
9871548
17.

Potent cyclic urea HIV protease inhibitors with 3-aminoindazole P2/P2' groups.

Rodgers JD, Johnson BL, Wang H, Erickson-Viitanen S, Klabe RM, Bacheler L, Cordova BC, Chang CH.

Bioorg Med Chem Lett. 1998 Apr 7;8(7):715-20.

PMID:
9871528
18.

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