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Items: 6


Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia.

Chan SM, Thomas D, Corces-Zimmerman MR, Xavy S, Rastogi S, Hong WJ, Zhao F, Medeiros BC, Tyvoll DA, Majeti R.

Nat Med. 2015 Feb;21(2):178-84. doi: 10.1038/nm.3788. Epub 2015 Jan 19.


Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.

Sinha S, Thomas D, Yu L, Gentles AJ, Jung N, Corces-Zimmerman MR, Chan SM, Reinisch A, Feinberg AP, Dill DL, Majeti R.

Blood. 2015 Jan 8;125(2):316-26. doi: 10.1182/blood-2014-03-566018. Epub 2014 Nov 14.


Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis.

Corces-Zimmerman MR, Majeti R.

Leukemia. 2014 Dec;28(12):2276-82. doi: 10.1038/leu.2014.211. Epub 2014 Jul 9. Review.


Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission.

Corces-Zimmerman MR, Hong WJ, Weissman IL, Medeiros BC, Majeti R.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2548-53. doi: 10.1073/pnas.1324297111. Epub 2014 Feb 3.


Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

Jan M, Snyder TM, Corces-Zimmerman MR, Vyas P, Weissman IL, Quake SR, Majeti R.

Sci Transl Med. 2012 Aug 29;4(149):149ra118. doi: 10.1126/scitranslmed.3004315.


Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.

Kauffman AL, Ashraf JM, Corces-Zimmerman MR, Landis JN, Murphy CT.

PLoS Biol. 2010 May 18;8(5):e1000372. doi: 10.1371/journal.pbio.1000372.

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