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Items: 47


The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions.

Seitz C, Huang J, Geiselhöringer AL, Galbani-Bianchi P, Michalek S, Phan TS, Reinhold C, Dietrich L, Schmidt C, Corazza N, Delgado E, Schnalzger T, Schoonjans K, Brunner T.

Sci Adv. 2019 Jul 17;5(7):eaav9732. doi: 10.1126/sciadv.aav9732. eCollection 2019 Jul.


Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss.

Wicki S, Gurzeler U, Corazza N, Genitsch V, Wong WW, Kaufmann T.

Int J Mol Sci. 2018 Feb 28;19(3). pii: E684. doi: 10.3390/ijms19030684.


Divergent Roles of Interferon-γ and Innate Lymphoid Cells in Innate and Adaptive Immune Cell-Mediated Intestinal Inflammation.

Brasseit J, Kwong Chung CKC, Noti M, Zysset D, Hoheisel-Dickgreber N, Genitsch V, Corazza N, Mueller C.

Front Immunol. 2018 Jan 24;9:23. doi: 10.3389/fimmu.2018.00023. eCollection 2018.


CD4 T cells are required for both development and maintenance of disease in a new mouse model of reversible colitis.

Brasseit J, Althaus-Steiner E, Faderl M, Dickgreber N, Saurer L, Genitsch V, Dolowschiak T, Li H, Finke D, Hardt WD, McCoy KD, Macpherson AJ, Corazza N, Noti M, Mueller C.

Mucosal Immunol. 2016 May;9(3):689-701. doi: 10.1038/mi.2015.93. Epub 2015 Sep 16.


Keeping bugs in check: The mucus layer as a critical component in maintaining intestinal homeostasis.

Faderl M, Noti M, Corazza N, Mueller C.

IUBMB Life. 2015 Apr;67(4):275-85. doi: 10.1002/iub.1374. Epub 2015 Apr 24. Review.


Tumor necrosis factor-related apoptosis-inducing ligand on NK cells protects from hepatic ischemia-reperfusion injury.

Fahrner R, Trochsler M, Corazza N, Graubardt N, Keogh A, Candinas D, Brunner T, Stroka D, Beldi G.

Transplantation. 2014 Jun 15;97(11):1102-9. doi: 10.1097/TP.0000000000000101.


TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner.

Badmann A, Langsch S, Keogh A, Brunner T, Kaufmann T, Corazza N.

Cell Death Dis. 2012 Dec 20;3:e447. doi: 10.1038/cddis.2012.185.


Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models.

Corazza N, Kaufmann T.

Allergy. 2012 Dec;67(12):1483-90. doi: 10.1111/all.12065. Epub 2012 Oct 29. Review.


Colon cancer cells produce immunoregulatory glucocorticoids.

Sidler D, Renzulli P, Schnoz C, Berger B, Schneider-Jakob S, Flück C, Inderbitzin D, Corazza N, Candinas D, Brunner T.

Oncoimmunology. 2012 Jul 1;1(4):529-530.


Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase-Bim axis and reveals glutathione-S-transferase P1 as Achilles' heel.

Sidler D, Brockmann A, Mueller J, Nachbur U, Corazza N, Renzulli P, Hemphill A, Brunner T.

Oncogene. 2012 Sep 13;31(37):4095-106. doi: 10.1038/onc.2011.575. Epub 2011 Dec 12.


The proapoptotic Bcl-2 family member Bim plays a central role during the development of virus-induced hepatitis.

Lauer C, Brunner T, Corazza N.

J Immunol. 2012 Jan 15;188(2):916-22. doi: 10.4049/jimmunol.1101864. Epub 2011 Dec 7.


Local glucocorticoid production in the mouse lung is induced by immune cell stimulation.

Hostettler N, Bianchi P, Gennari-Moser C, Kassahn D, Schoonjans K, Corazza N, Brunner T.

Allergy. 2012 Feb;67(2):227-34. doi: 10.1111/j.1398-9995.2011.02749.x. Epub 2011 Nov 24.


Metabolic pathway and distribution of superparamagnetic iron oxide nanoparticles: in vivo study.

Schlachter EK, Widmer HR, Bregy A, Lönnfors-Weitzel T, Vajtai I, Corazza N, Bernau VJ, Weitzel T, Mordasini P, Slotboom J, Herrmann G, Bogni S, Hofmann H, Frenz M, Reinert M.

Int J Nanomedicine. 2011;6:1793-800. doi: 10.2147/IJN.S23638. Epub 2011 Aug 26.


Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage.

Badmann A, Keough A, Kaufmann T, Bouillet P, Brunner T, Corazza N.

Cell Death Dis. 2011 Jun 9;2:e171. doi: 10.1038/cddis.2011.55.


Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid.

Schneider-Jakob S, Corazza N, Badmann A, Sidler D, Stuber-Roos R, Keogh A, Frese S, Tschan M, Brunner T.

Cell Death Dis. 2010 Oct 21;1:e86. doi: 10.1038/cddis.2010.66.


Colon cancer cells produce immunoregulatory glucocorticoids.

Sidler D, Renzulli P, Schnoz C, Berger B, Schneider-Jakob S, Flück C, Inderbitzin D, Corazza N, Candinas D, Brunner T.

Oncogene. 2011 May 26;30(21):2411-9. doi: 10.1038/onc.2010.629. Epub 2011 Jan 24.


Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner.

Schmich K, Schlatter R, Corazza N, Sá Ferreira K, Ederer M, Brunner T, Borner C, Merfort I.

Hepatology. 2011 Jan;53(1):282-92. doi: 10.1002/hep.23987. Epub 2010 Sep 24.


TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis.

Noti M, Corazza N, Mueller C, Berger B, Brunner T.

J Exp Med. 2010 May 10;207(5):1057-66. doi: 10.1084/jem.20090849. Epub 2010 May 3.


Lipopolysaccharide induces intestinal glucocorticoid synthesis in a TNFalpha-dependent manner.

Noti M, Corazza N, Tuffin G, Schoonjans K, Brunner T.

FASEB J. 2010 May;24(5):1340-6. doi: 10.1096/fj.09-140913. Epub 2010 Jan 7.


TRAIL-induced apoptosis: between tumor therapy and immunopathology.

Corazza N, Kassahn D, Jakob S, Badmann A, Brunner T.

Ann N Y Acad Sci. 2009 Aug;1171:50-8. doi: 10.1111/j.1749-6632.2009.04905.x. Review.


Phenotyping, functional characterization, and developmental changes in canine intestinal intraepithelial lymphocytes.

Luckschander N, Pfammatter NS, Sidler D, Jakob S, Burgener IA, Moore PF, Zurbriggen A, Corazza N, Brunner T.

Vet Res. 2009 Nov-Dec;40(6):58. doi: 10.1051/vetres/2009042. Epub 2009 Jul 28.


Immune cell-mediated liver injury.

Corazza N, Badmann A, Lauer C.

Semin Immunopathol. 2009 Jul;31(2):267-77. doi: 10.1007/s00281-009-0168-1. Epub 2009 Jun 17. Review.


Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand.

Herold S, Steinmueller M, von Wulffen W, Cakarova L, Pinto R, Pleschka S, Mack M, Kuziel WA, Corazza N, Brunner T, Seeger W, Lohmeyer J.

J Exp Med. 2008 Dec 22;205(13):3065-77. doi: 10.1084/jem.20080201. Epub 2008 Dec 8.


Distinct but complementary roles of Fas ligand and Bim in homeostatic T cell apoptosis.

Kassahn D, Brunner T, Corazza N.

Cell Cycle. 2008 Nov 1;7(21):3469-71. Epub 2008 Nov 5. No abstract available.


Cell cycle-dependent regulation of extra-adrenal glucocorticoid synthesis in murine intestinal epithelial cells.

Atanasov AG, Leiser D, Roesselet C, Noti M, Corazza N, Schoonjans K, Brunner T.

FASEB J. 2008 Dec;22(12):4117-25. doi: 10.1096/fj.08-114157. Epub 2008 Aug 18.


Detection of apoptosis in vivo using antibodies against caspase-induced neo-epitopes.

Jakob S, Corazza N, Diamantis E, Kappeler A, Brunner T.

Methods. 2008 Mar;44(3):255-61. doi: 10.1016/j.ymeth.2007.11.004.


LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease.

Coste A, Dubuquoy L, Barnouin R, Annicotte JS, Magnier B, Notti M, Corazza N, Antal MC, Metzger D, Desreumaux P, Brunner T, Auwerx J, Schoonjans K.

Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13098-103. Epub 2007 Aug 1.


Activation of non-ischemic, hypoxia-inducible signalling pathways up-regulate cytoprotective genes in the murine liver.

Plock J, Frese S, Keogh A, Bisch-Knaden S, Ayuni E, Corazza N, Weikert C, Jakob S, Erni D, Dufour JF, Brunner T, Candinas D, Stroka D.

J Hepatol. 2007 Oct;47(4):538-45. Epub 2007 Jun 4.


Differential regulation of glucocorticoid synthesis in murine intestinal epithelial versus adrenocortical cell lines.

Mueller M, Atanasov A, Cima I, Corazza N, Schoonjans K, Brunner T.

Endocrinology. 2007 Mar;148(3):1445-53. Epub 2006 Dec 14.


TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.

Corazza N, Jakob S, Schaer C, Frese S, Keogh A, Stroka D, Kassahn D, Torgler R, Mueller C, Schneider P, Brunner T.

J Clin Invest. 2006 Sep;116(9):2493-9.


Contribution of transmembrane tumor necrosis factor to host defense against Mycobacterium bovis bacillus Calmette-guerin and Mycobacterium tuberculosis infections.

Olleros ML, Guler R, Vesin D, Parapanov R, Marchal G, Martinez-Soria E, Corazza N, Pache JC, Mueller C, Garcia I.

Am J Pathol. 2005 Apr;166(4):1109-20.


TRAIL and immunity: more than a license to kill tumor cells.

Corazza N, Brumatti G, Schaer C, Cima I, Wasem C, Brunner T.

Cell Death Differ. 2004 Dec;11 Suppl 2:S122-5. No abstract available.


Intestinal epithelial cells synthesize glucocorticoids and regulate T cell activation.

Cima I, Corazza N, Dick B, Fuhrer A, Herren S, Jakob S, Ayuni E, Mueller C, Brunner T.

J Exp Med. 2004 Dec 20;200(12):1635-46. Epub 2004 Dec 13.


TRAIL and thymocyte apoptosis: not so deadly?

Corazza N, Brumatti G, Jakob S, Villunger A, Brunner T.

Cell Death Differ. 2004 Dec;11 Suppl 2:S213-5. No abstract available.


Transmembrane tumor necrosis factor is a potent inducer of colitis even in the absence of its secreted form.

Corazza N, Brunner T, Buri C, Rihs S, Imboden MA, Seibold I, Mueller C.

Gastroenterology. 2004 Sep;127(3):816-25.


CD1d function is regulated by microsomal triglyceride transfer protein.

Brozovic S, Nagaishi T, Yoshida M, Betz S, Salas A, Chen D, Kaser A, Glickman J, Kuo T, Little A, Morrison J, Corazza N, Kim JY, Colgan SP, Young SG, Exley M, Blumberg RS.

Nat Med. 2004 May;10(5):535-9. Epub 2004 Apr 25.


Fas (CD95/Apo-1) ligand regulation in T cell homeostasis, cell-mediated cytotoxicity and immune pathology.

Brunner T, Wasem C, Torgler R, Cima I, Jakob S, Corazza N.

Semin Immunol. 2003 Jun;15(3):167-76. Review.


Delineation of a CD1d-restricted antigen presentation pathway associated with human and mouse intestinal epithelial cells.

van de Wal Y, Corazza N, Allez M, Mayer LF, Iijima H, Ryan M, Cornwall S, Kaiserlian D, Hershberg R, Koezuka Y, Colgan SP, Blumberg RS.

Gastroenterology. 2003 May;124(5):1420-31.


Sensitizing antigen-specific CD8+ T cells for accelerated suicide causes immune incompetence.

Wasem C, Arnold D, Saurer L, Corazza N, Jakob S, Herren S, Vallan C, Mueller C, Brunner T.

J Clin Invest. 2003 Apr;111(8):1191-9.


Disruption of T helper 2-immune responses in Epstein-Barr virus-induced gene 3-deficient mice.

Nieuwenhuis EE, Neurath MF, Corazza N, Iijima H, Trgovcich J, Wirtz S, Glickman J, Bailey D, Yoshida M, Galle PR, Kronenberg M, Birkenbach M, Blumberg RS.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16951-6. Epub 2002 Dec 13.


CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung.

Nieuwenhuis EE, Matsumoto T, Exley M, Schleipman RA, Glickman J, Bailey DT, Corazza N, Colgan SP, Onderdonk AB, Blumberg RS.

Nat Med. 2002 Jun;8(6):588-93.


Transmembrane TNF induces an efficient cell-mediated immunity and resistance to Mycobacterium bovis bacillus Calmette-Guérin infection in the absence of secreted TNF and lymphotoxin-alpha.

Olleros ML, Guler R, Corazza N, Vesin D, Eugster HP, Marchal G, Chavarot P, Mueller C, Garcia I.

J Immunol. 2002 Apr 1;168(7):3394-401.


The multiple roles of major histocompatibility complex class-I-like molecules in mucosal immune function.

Blumberg RS, van de Wal Y, Claypool S, Corazza N, Dickinson B, Nieuwenhuis E, Pitman R, Spiekermann G, Zhu X, Colgan S, Lencer WI.

Acta Odontol Scand. 2001 Jun;59(3):139-44. Review.


Noncleavable transmembrane mouse tumor necrosis factor-alpha (TNFalpha) mediates effects distinct from those of wild-type TNFalpha in vitro and in vivo.

Mueller C, Corazza N, Trachsel-Løseth S, Eugster HP, Bühler-Jungo M, Brunner T, Imboden MA.

J Biol Chem. 1999 Dec 31;274(53):38112-8.


Activated CD4+ and CD8+ cytotoxic cells are present in increased numbers in the intestinal mucosa from patients with active inflammatory bowel disease.

Müller S, Lory J, Corazza N, Griffiths GM, Z'graggen K, Mazzucchelli L, Kappeler A, Mueller C.

Am J Pathol. 1998 Jan;152(1):261-8.

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