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Items: 1 to 50 of 61

1.

Endothelial cell clonal expansion in the development of cerebral cavernous malformations.

Malinverno M, Maderna C, Abu Taha A, Corada M, Orsenigo F, Valentino M, Pisati F, Fusco C, Graziano P, Giannotta M, Yu QC, Zeng YA, Lampugnani MG, Magnusson PU, Dejana E.

Nat Commun. 2019 Jun 24;10(1):2761. doi: 10.1038/s41467-019-10707-x.

2.

Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier.

Corada M, Orsenigo F, Bhat GP, Conze LL, Breviario F, Cunha SI, Claesson-Welsh L, Beznoussenko GV, Mironov AA, Bacigaluppi M, Martino G, Pitulescu ME, Adams RH, Magnusson P, Dejana E.

Circ Res. 2019 Feb 15;124(4):511-525. doi: 10.1161/CIRCRESAHA.118.313316.

3.

VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression.

Morini MF, Giampietro C, Corada M, Pisati F, Lavarone E, Cunha SI, Conze LL, O'Reilly N, Joshi D, Kjaer S, George R, Nye E, Ma A, Jin J, Mitter R, Lupia M, Cavallaro U, Pasini D, Calado DP, Dejana E, Taddei A.

Circ Res. 2018 Jan 19;122(2):231-245. doi: 10.1161/CIRCRESAHA.117.312392. Epub 2017 Dec 12.

4.

Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi: 10.1242/dev.146241.

Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Fossat N, Radziewic T, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Tam PPL, Carroll J, Dejana E, Schulte-Merker S, Hogan BM, Beltrame M, De Val S, Francois M.

Development. 2017 Oct 15;144(20):3847-3848. doi: 10.1242/dev.159715. No abstract available.

5.

Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.

Erba BG, Gruppi C, Corada M, Pisati F, Rosti V, Bartalucci N, Villeval JL, Vannucchi AM, Barosi G, Balduini A, Dejana E.

Am J Pathol. 2017 Aug;187(8):1879-1892. doi: 10.1016/j.ajpath.2017.04.006.

6.

SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.

Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M.

Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15. Erratum in: Development. 2017 Oct 15;144(20):3847-3848.

7.

Peg3/PW1 Is a Marker of a Subset of Vessel Associated Endothelial Progenitors.

Malinverno M, Corada M, Ferrarini L, Formicola L, Marazzi G, Sassoon D, Dejana E.

Stem Cells. 2017 May;35(5):1328-1340. doi: 10.1002/stem.2566. Epub 2017 Feb 5.

8.

β-Catenin Is Required for Endothelial Cyp1b1 Regulation Influencing Metabolic Barrier Function.

Ziegler N, Awwad K, Fisslthaler B, Reis M, Devraj K, Corada M, Minardi SP, Dejana E, Plate KH, Fleming I, Liebner S.

J Neurosci. 2016 Aug 24;36(34):8921-35. doi: 10.1523/JNEUROSCI.0148-16.2016.

9.

Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice.

Gertz K, Kronenberg G, Uhlemann R, Prinz V, Marquina R, Corada M, Dejana E, Endres M.

BMC Neurol. 2016 Aug 18;16(1):144. doi: 10.1186/s12883-016-0670-8.

10.

Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.

Chen Q, Zhang H, Liu Y, Adams S, Eilken H, Stehling M, Corada M, Dejana E, Zhou B, Adams RH.

Nat Commun. 2016 Aug 12;7:12422. doi: 10.1038/ncomms12422.

11.

The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling.

Giampietro C, Disanza A, Bravi L, Barrios-Rodiles M, Corada M, Frittoli E, Savorani C, Lampugnani MG, Boggetti B, Niessen C, Wrana JL, Scita G, Dejana E.

J Cell Biol. 2015 Dec 21;211(6):1177-92. doi: 10.1083/jcb.201501089. Epub 2015 Dec 14.

12.

KLF4 is a key determinant in the development and progression of cerebral cavernous malformations.

Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, Morini MF, Maddaluno L, Baeyens N, Adams RH, Jain MK, Owens GK, Schwartz M, Lampugnani MG, Dejana E.

EMBO Mol Med. 2016 Jan 1;8(1):6-24. doi: 10.15252/emmm.201505433.

13.

Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice.

Bravi L, Rudini N, Cuttano R, Giampietro C, Maddaluno L, Ferrarini L, Adams RH, Corada M, Boulday G, Tournier-Lasserve E, Dejana E, Lampugnani MG.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8421-6. doi: 10.1073/pnas.1501352112. Epub 2015 Jun 24.

14.

Signaling pathways in the specification of arteries and veins.

Corada M, Morini MF, Dejana E.

Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2372-7. doi: 10.1161/ATVBAHA.114.303218. Epub 2014 Aug 28. Review.

PMID:
25169934
15.

Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles.

Giannotta M, Benedetti S, Tedesco FS, Corada M, Trani M, D'Antuono R, Millet Q, Orsenigo F, Gálvez BG, Cossu G, Dejana E.

EMBO Mol Med. 2014 Feb;6(2):239-58. doi: 10.1002/emmm.201302520. Epub 2013 Dec 30.

16.

Sox17 is indispensable for acquisition and maintenance of arterial identity.

Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E.

Nat Commun. 2013;4:2609. doi: 10.1038/ncomms3609.

17.

Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro.

Paolinelli R, Corada M, Ferrarini L, Devraj K, Artus C, Czupalla CJ, Rudini N, Maddaluno L, Papa E, Engelhardt B, Couraud PO, Liebner S, Dejana E.

PLoS One. 2013 Aug 5;8(8):e70233. doi: 10.1371/journal.pone.0070233. Print 2013.

18.

EndMT contributes to the onset and progression of cerebral cavernous malformations.

Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, Ferrarini L, Orsenigo F, Papa E, Boulday G, Tournier-Lasserve E, Chapon F, Richichi C, Retta SF, Lampugnani MG, Dejana E.

Nature. 2013 Jun 27;498(7455):492-6. doi: 10.1038/nature12207. Epub 2013 Jun 9.

PMID:
23748444
19.

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo.

Orsenigo F, Giampietro C, Ferrari A, Corada M, Galaup A, Sigismund S, Ristagno G, Maddaluno L, Koh GY, Franco D, Kurtcuoglu V, Poulikakos D, Baluk P, McDonald D, Grazia Lampugnani M, Dejana E.

Nat Commun. 2012;3:1208. doi: 10.1038/ncomms2199.

20.

Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells.

Giampietro C, Taddei A, Corada M, Sarra-Ferraris GM, Alcalay M, Cavallaro U, Orsenigo F, Lampugnani MG, Dejana E.

Blood. 2012 Mar 1;119(9):2159-70. doi: 10.1182/blood-2011-09-381012. Epub 2012 Jan 12.

21.

Abrogation of junctional adhesion molecule-A expression induces cell apoptosis and reduces breast cancer progression.

Murakami M, Giampietro C, Giannotta M, Corada M, Torselli I, Orsenigo F, Cocito A, d'Ario G, Mazzarol G, Confalonieri S, Di Fiore PP, Dejana E.

PLoS One. 2011;6(6):e21242. doi: 10.1371/journal.pone.0021242. Epub 2011 Jun 17.

22.

The molecular basis of the blood brain barrier differentiation and maintenance. Is it still a mystery?

Paolinelli R, Corada M, Orsenigo F, Dejana E.

Pharmacol Res. 2011 Mar;63(3):165-71. doi: 10.1016/j.phrs.2010.11.012. Epub 2010 Dec 15. Review.

PMID:
21167284
23.

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling.

Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E.

Dev Cell. 2010 Jun 15;18(6):938-49. doi: 10.1016/j.devcel.2010.05.006.

24.

Inactivation of junctional adhesion molecule-A enhances antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration.

Murakami M, Francavilla C, Torselli I, Corada M, Maddaluno L, Sica A, Matteoli G, Iliev ID, Mantovani A, Rescigno M, Cavallaro U, Dejana E.

Cancer Res. 2010 Mar 1;70(5):1759-65. doi: 10.1158/0008-5472.CAN-09-1703. Epub 2010 Feb 16.

25.

JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling.

Cera MR, Fabbri M, Molendini C, Corada M, Orsenigo F, Rehberg M, Reichel CA, Krombach F, Pardi R, Dejana E.

J Cell Sci. 2009 Jan 15;122(Pt 2):268-77. doi: 10.1242/jcs.037127.

26.

Wnt/beta-catenin signaling controls development of the blood-brain barrier.

Liebner S, Corada M, Bangsow T, Babbage J, Taddei A, Czupalla CJ, Reis M, Felici A, Wolburg H, Fruttiger M, Taketo MM, von Melchner H, Plate KH, Gerhardt H, Dejana E.

J Cell Biol. 2008 Nov 3;183(3):409-17. doi: 10.1083/jcb.200806024. Epub 2008 Oct 27.

27.

VE-cadherin is a critical endothelial regulator of TGF-beta signalling.

Rudini N, Felici A, Giampietro C, Lampugnani M, Corada M, Swirsding K, Garrè M, Liebner S, Letarte M, ten Dijke P, Dejana E.

EMBO J. 2008 Apr 9;27(7):993-1004. doi: 10.1038/emboj.2008.46. Epub 2008 Mar 13.

28.

Functionally specialized junctions between endothelial cells of lymphatic vessels.

Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, Butz S, Vestweber D, Corada M, Molendini C, Dejana E, McDonald DM.

J Exp Med. 2007 Oct 1;204(10):2349-62. Epub 2007 Sep 10.

29.

JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration.

Woodfin A, Reichel CA, Khandoga A, Corada M, Voisin MB, Scheiermann C, Haskard DO, Dejana E, Krombach F, Nourshargh S.

Blood. 2007 Sep 15;110(6):1848-56. Epub 2007 May 15.

30.

Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice.

Zernecke A, Liehn EA, Fraemohs L, von Hundelshausen P, Koenen RR, Corada M, Dejana E, Weber C.

Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):e10-3. Epub 2005 Nov 23.

PMID:
16306427
31.

Epac1 regulates integrity of endothelial cell junctions through VE-cadherin.

Kooistra MR, Corada M, Dejana E, Bos JL.

FEBS Lett. 2005 Sep 12;579(22):4966-72.

32.

Junctional adhesion molecule-A-deficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury.

Corada M, Chimenti S, Cera MR, Vinci M, Salio M, Fiordaliso F, De Angelis N, Villa A, Bossi M, Staszewsky LI, Vecchi A, Parazzoli D, Motoike T, Latini R, Dejana E.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10634-9. Epub 2005 Jul 18.

33.

Downregulation of vascular endothelial-cadherin expression is associated with an increase in vascular tumor growth and hemorrhagic complications.

Zanetta L, Corada M, Grazia Lampugnani M, Zanetti A, Breviario F, Moons L, Carmeliet P, Pepper MS, Dejana E.

Thromb Haemost. 2005 Jun;93(6):1041-6.

PMID:
15968386
34.

Junctional adhesion molecule-A deficiency increases hepatic ischemia-reperfusion injury despite reduction of neutrophil transendothelial migration.

Khandoga A, Kessler JS, Meissner H, Hanschen M, Corada M, Motoike T, Enders G, Dejana E, Krombach F.

Blood. 2005 Jul 15;106(2):725-33. Epub 2005 Apr 12.

35.

VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly.

Crosby CV, Fleming PA, Argraves WS, Corada M, Zanetta L, Dejana E, Drake CJ.

Blood. 2005 Apr 1;105(7):2771-6. Epub 2004 Dec 16.

36.

Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice.

Cera MR, Del Prete A, Vecchi A, Corada M, Martin-Padura I, Motoike T, Tonetti P, Bazzoni G, Vermi W, Gentili F, Bernasconi S, Sato TN, Mantovani A, Dejana E.

J Clin Invest. 2004 Sep;114(5):729-38.

37.

VE-cadherin expression and clustering maintain low levels of survivin in endothelial cells.

Iurlaro M, Demontis F, Corada M, Zanetta L, Drake C, Gariboldi M, Peiro S, Cano A, Navarro P, Cattelino A, Tognin S, Marchisio PC, Dejana E.

Am J Pathol. 2004 Jul;165(1):181-9.

38.

Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis.

Spagnuolo R, Corada M, Orsenigo F, Zanetta L, Deuschle U, Sandy P, Schneider C, Drake CJ, Breviario F, Dejana E.

Blood. 2004 Apr 15;103(8):3005-12. Epub 2003 Dec 11.

39.

Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148.

Grazia Lampugnani M, Zanetti A, Corada M, Takahashi T, Balconi G, Breviario F, Orsenigo F, Cattelino A, Kemler R, Daniel TO, Dejana E.

J Cell Biol. 2003 May 26;161(4):793-804.

40.

A monoclonal antibody to vascular endothelial-cadherin inhibits tumor angiogenesis without side effects on endothelial permeability.

Corada M, Zanetta L, Orsenigo F, Breviario F, Lampugnani MG, Bernasconi S, Liao F, Hicklin DJ, Bohlen P, Dejana E.

Blood. 2002 Aug 1;100(3):905-11.

41.

VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam.

Lampugnani MG, Zanetti A, Breviario F, Balconi G, Orsenigo F, Corada M, Spagnuolo R, Betson M, Braga V, Dejana E.

Mol Biol Cell. 2002 Apr;13(4):1175-89.

42.

Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism to control vascular endothelial growth factor receptor-2 signaling.

Zanetti A, Lampugnani MG, Balconi G, Breviario F, Corada M, Lanfrancone L, Dejana E.

Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):617-22.

PMID:
11950700
43.

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability.

Corada M, Liao F, Lindgren M, Lampugnani MG, Breviario F, Frank R, Muller WA, Hicklin DJ, Bohlen P, Dejana E.

Blood. 2001 Mar 15;97(6):1679-84.

44.

Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo.

Corada M, Mariotti M, Thurston G, Smith K, Kunkel R, Brockhaus M, Lampugnani MG, Martin-Padura I, Stoppacciaro A, Ruco L, McDonald DM, Ward PA, Dejana E.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9815-20.

45.

Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells.

Esser S, Lampugnani MG, Corada M, Dejana E, Risau W.

J Cell Sci. 1998 Jul;111 ( Pt 13):1853-65.

46.

Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells.

Lampugnani MG, Corada M, Andriopoulou P, Esser S, Risau W, Dejana E.

J Cell Sci. 1997 Sep;110 ( Pt 17):2065-77.

47.

Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions.

Del Maschio A, Zanetti A, Corada M, Rival Y, Ruco L, Lampugnani MG, Dejana E.

J Cell Biol. 1996 Oct;135(2):497-510.

48.

Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin).

Caveda L, Martin-Padura I, Navarro P, Breviario F, Corada M, Gulino D, Lampugnani MG, Dejana E.

J Clin Invest. 1996 Aug 15;98(4):886-93.

49.

Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin.

Breviario F, Caveda L, Corada M, Martin-Padura I, Navarro P, Golay J, Introna M, Gulino D, Lampugnani MG, Dejana E.

Arterioscler Thromb Vasc Biol. 1995 Aug;15(8):1229-39.

PMID:
7627717
50.

Endothelial cell-to-cell junctions.

Dejana E, Corada M, Lampugnani MG.

FASEB J. 1995 Jul;9(10):910-8. Review.

PMID:
7615160

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