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Items: 12


The promise of CD4+FoxP3+ regulatory T-cell manipulation in vivo: applications for allogeneic hematopoietic stem cell transplantation.

Copsel S, Wolf D, Komanduri KV, Levy RB.

Haematologica. 2019 Jul;104(7):1309-1321. doi: 10.3324/haematol.2018.198838. Epub 2019 Jun 20. Review.


BET Bromodomain Inhibitors Which Permit Treg Function Enable a Combinatorial Strategy to Suppress GVHD in Pre-clinical Allogeneic HSCT.

Copsel SN, Lightbourn CO, Barreras H, Lohse I, Wolf D, Bader CS, Manov J, Kale BJ, Shah D, Brothers SP, Perez VL, Komanduri KV, Wahlestedt C, Levy RB.

Front Immunol. 2019 Jan 24;9:3104. doi: 10.3389/fimmu.2018.03104. eCollection 2018.


Superior immune reconstitution using Treg-expanded donor cells versus PTCy treatment in preclinical HSCT models.

Wolf D, Bader CS, Barreras H, Copsel S, Pfeiffer BJ, Lightbourn CO, Altman NH, Komanduri KV, Levy RB.

JCI Insight. 2018 Oct 18;3(20). pii: 121717. doi: 10.1172/jci.insight.121717.


Very Low Numbers of CD4+ FoxP3+ Tregs Expanded in Donors via TL1A-Ig and Low-Dose IL-2 Exhibit a Distinct Activation/Functional Profile and Suppress GVHD in a Preclinical Model.

Copsel S, Wolf D, Kale B, Barreras H, Lightbourn CO, Bader CS, Alperstein W, Altman NH, Komanduri KV, Levy RB.

Biol Blood Marrow Transplant. 2018 Sep;24(9):1788-1794. doi: 10.1016/j.bbmt.2018.04.026. Epub 2018 May 8.


Marked in Vivo Donor Regulatory T Cell Expansion via Interleukin-2 and TL1A-Ig Stimulation Ameliorates Graft-versus-Host Disease but Preserves Graft-versus-Leukemia in Recipients after Hematopoietic Stem Cell Transplantation.

Wolf D, Barreras H, Bader CS, Copsel S, Lightbourn CO, Pfeiffer BJ, Altman NH, Podack ER, Komanduri KV, Levy RB.

Biol Blood Marrow Transplant. 2017 May;23(5):757-766. doi: 10.1016/j.bbmt.2017.02.013. Epub 2017 Feb 20.


A Novel Effect of β-Adrenergic Receptor on Mammary Branching Morphogenesis and its Possible Implications in Breast Cancer.

Gargiulo L, May M, Rivero EM, Copsel S, Lamb C, Lydon J, Davio C, Lanari C, Lüthy IA, Bruzzone A.

J Mammary Gland Biol Neoplasia. 2017 Mar;22(1):43-57. doi: 10.1007/s10911-017-9371-1. Epub 2017 Jan 11.


Histamine H2 Receptor in Blood Cells: A Suitable Target for the Treatment of Acute Myeloid Leukemia.

Monczor F, Copsel S, Fernandez N, Davio C, Shayo C.

Handb Exp Pharmacol. 2017;241:141-160. doi: 10.1007/164_2016_8. Review.


Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines.

Gargiulo L, Copsel S, Rivero EM, Galés C, Sénard JM, Lüthy IA, Davio C, Bruzzone A.

Oncotarget. 2014 Oct 30;5(20):10058-69.


Multidrug resistance protein 4/ ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia.

Copsel S, Bruzzone A, May M, Beyrath J, Wargon V, Cany J, Russel FG, Shayo C, Davio C.

Oncotarget. 2014 Oct 15;5(19):9308-21.


Atrial natriuretic factor stimulates efflux of cAMP in rat exocrine pancreas via multidrug resistance-associated proteins.

Rodríguez MR, Diez F, Ventimiglia MS, Morales V, Copsel S, Vatta MS, Davio CA, Bianciotti LG.

Gastroenterology. 2011 Apr;140(4):1292-302. doi: 10.1053/j.gastro.2010.12.053. Epub 2011 Jan 13.


Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation.

Copsel S, Garcia C, Diez F, Vermeulem M, Baldi A, Bianciotti LG, Russel FG, Shayo C, Davio C.

J Biol Chem. 2011 Mar 4;286(9):6979-88. doi: 10.1074/jbc.M110.166868. Epub 2011 Jan 4.


Expression of a G protein-coupled receptor (GPCR) leads to attenuation of signaling by other GPCRs: experimental evidence for a spontaneous GPCR constitutive inactive form.

Tubio MR, Fernandez N, Fitzsimons CP, Copsel S, Santiago S, Shayo C, Davio C, Monczor F.

J Biol Chem. 2010 May 14;285(20):14990-8. doi: 10.1074/jbc.M109.099689. Epub 2010 Mar 18.

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