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Items: 16

1.

IL1R1 is required for celastrol's leptin-sensitization and antiobesity effects.

Feng X, Guan D, Auen T, Choi JW, Salazar Hernández MA, Lee J, Chun H, Faruk F, Kaplun E, Herbert Z, Copps KD, Ozcan U.

Nat Med. 2019 Apr;25(4):575-582. doi: 10.1038/s41591-019-0358-x. Epub 2019 Mar 4.

PMID:
30833749
2.

Publisher Correction: Inactivating hepatic follistatin alleviates hyperglycemia.

Tao R, Wang C, Stöhr O, Qiu W, Hu Y, Miao J, Dong XC, Leng S, Stefater M, Stylopoulos N, Lin L, Copps KD, White MF.

Nat Med. 2018 Oct;24(10):1628. doi: 10.1038/s41591-018-0129-0.

PMID:
30111893
3.

Inactivating hepatic follistatin alleviates hyperglycemia.

Tao R, Wang C, Stöhr O, Qiu W, Hu Y, Miao J, Dong XC, Leng S, Stefater M, Stylopoulos N, Lin L, Copps KD, White MF.

Nat Med. 2018 Jul;24(7):1058-1069. doi: 10.1038/s41591-018-0048-0. Epub 2018 Jun 4. Erratum in: Nat Med. 2018 Oct;24(10):1628.

4.

Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.

Xu H, Lee MS, Tsai PY, Adler AS, Curry NL, Challa S, Freinkman E, Hitchcock DS, Copps KD, White MF, Bronson RT, Marcotrigiano M, Wu Y, Clish CB, Kalaany NY.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4228-4233. doi: 10.1073/pnas.1718414115. Epub 2018 Apr 2.

5.

Correction for Long et al., "Insulin Receptor Substrates Irs1 and Irs2 Coordinate Skeletal Muscle Growth and Metabolism via the Akt and AMPK Pathways".

Long YC, Cheng Z, Copps KD, White MF.

Mol Cell Biol. 2017 Jul 14;37(15). pii: e00232-17. doi: 10.1128/MCB.00232-17. Print 2017 Aug 1. No abstract available.

6.

Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.

Copps KD, Hançer NJ, Qiu W, White MF.

J Biol Chem. 2016 Apr 15;291(16):8602-17. doi: 10.1074/jbc.M116.714915. Epub 2016 Feb 4.

7.

Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.

Hançer NJ, Qiu W, Cherella C, Li Y, Copps KD, White MF.

J Biol Chem. 2014 May 2;289(18):12467-84. doi: 10.1074/jbc.M114.554162. Epub 2014 Mar 20.

8.

IRS1Ser³⁰⁷ phosphorylation does not mediate mTORC1-induced insulin resistance.

Herrema H, Lee J, Zhou Y, Copps KD, White MF, Ozcan U.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):689-93. doi: 10.1016/j.bbrc.2013.12.023. Epub 2013 Dec 11.

9.

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2.

Copps KD, White MF.

Diabetologia. 2012 Oct;55(10):2565-2582. doi: 10.1007/s00125-012-2644-8. Epub 2012 Aug 8. Review.

10.

Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling.

Matveyenko AV, Liuwantara D, Gurlo T, Kirakossian D, Dalla Man C, Cobelli C, White MF, Copps KD, Volpi E, Fujita S, Butler PC.

Diabetes. 2012 Sep;61(9):2269-79. doi: 10.2337/db11-1462. Epub 2012 Jun 11.

11.

Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways.

Long YC, Cheng Z, Copps KD, White MF.

Mol Cell Biol. 2011 Feb;31(3):430-41. doi: 10.1128/MCB.00983-10. Epub 2010 Dec 6. Erratum in: Mol Cell Biol. 2017 Jul 14;37(15):.

12.

Irs1 serine 307 promotes insulin sensitivity in mice.

Copps KD, Hancer NJ, Opare-Ado L, Qiu W, Walsh C, White MF.

Cell Metab. 2010 Jan;11(1):84-92. doi: 10.1016/j.cmet.2009.11.003.

13.

The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.

Guo S, Copps KD, Dong X, Park S, Cheng Z, Pocai A, Rossetti L, Sajan M, Farese RV, White MF.

Mol Cell Biol. 2009 Sep;29(18):5070-83. doi: 10.1128/MCB.00138-09. Epub 2009 Jul 13.

14.

Breathing room: the (un)natural history of adipose microhypoxia and insulin resistance.

Copps KD, White MF.

Diabetes. 2009 Jan;58(1):26-7. doi: 10.2337/db08-1517. No abstract available.

15.

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.

Dong XC, Copps KD, Guo S, Li Y, Kollipara R, DePinho RA, White MF.

Cell Metab. 2008 Jul;8(1):65-76. doi: 10.1016/j.cmet.2008.06.006.

16.

Phosphorylation of Irs1 at SER-522 inhibits insulin signaling.

Giraud J, Haas M, Feener EP, Copps KD, Dong X, Dunn SL, White MF.

Mol Endocrinol. 2007 Sep;21(9):2294-302. Epub 2007 Jun 19.

PMID:
17579213

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