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Items: 1 to 50 of 51

1.

NaV1.8: a novel contributor to cardiac arrhythmogenesis in heart failure.

Coppini R, Ferrantini C.

Cardiovasc Res. 2018 Aug 29. doi: 10.1093/cvr/cvy210. [Epub ahead of print] No abstract available.

PMID:
30169598
2.

Real-time optical manipulation of cardiac conduction in intact hearts.

Scardigli M, Müllenbroich C, Margoni E, Cannazzaro S, Crocini C, Ferrantini C, Coppini R, Yan P, Loew LM, Campione M, Bocchi L, Giulietti D, Cerbai E, Poggesi C, Bub G, Pavone FS, Sacconi L.

J Physiol. 2018 Sep;596(17):3841-3858. doi: 10.1113/JP276283. Epub 2018 Aug 7.

3.

Channelopathies, cardiac hypertrophy, and the theory of light.

Olivotto I, Coppini R.

Eur Heart J. 2018 Aug 14;39(31):2908-2910. doi: 10.1093/eurheartj/ehy297. No abstract available.

PMID:
29931202
4.

Defining the diagnostic effectiveness of genes for inclusion in panels: the experience of two decades of genetic testing for hypertrophic cardiomyopathy at a single center.

Mazzarotto F, Girolami F, Boschi B, Barlocco F, Tomberli A, Baldini K, Coppini R, Tanini I, Bardi S, Contini E, Cecchi F, Pelo E, Cook SA, Cerbai E, Poggesi C, Torricelli F, Walsh R, Olivotto I.

Genet Med. 2018 Jun 6. doi: 10.1038/s41436-018-0046-0. [Epub ahead of print]

PMID:
29875424
5.

Oleuropein Aglycone Protects against MAO-A-Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB.

Miceli C, Santin Y, Manzella N, Coppini R, Berti A, Stefani M, Parini A, Mialet-Perez J, Nediani C.

Oxid Med Cell Longev. 2018 Mar 26;2018:8067592. doi: 10.1155/2018/8067592. eCollection 2018.

6.

Late sodium current inhibitors to treat exercise-induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium.

Ferrantini C, Pioner JM, Mazzoni L, Gentile F, Tosi B, Rossi A, Belardinelli L, Tesi C, Palandri C, Matucci R, Cerbai E, Olivotto I, Poggesi C, Mugelli A, Coppini R.

Br J Pharmacol. 2018 Jul;175(13):2635-2652. doi: 10.1111/bph.14223. Epub 2018 May 3.

7.

[Consensus document and recommendations for the prevention of cardiovascular disease in Italy - 2018].

Volpe M, Tocci G, Accettura D, Battistoni A, Bellone S, Bellotti P, Bertolotti M, Borghi C, Casasco M, Consoli A, Coppini R, Corsini A, Costanzo G, Desideri G, Ferri C, Galanti G, Giada F, Icardi G, Lombardi N, Modena MG, Modesti PA, Monti G, Mugelli A, Orsi A, Parati G, Pedretti RF, Perseghin G, Pirro M, Ricotti R, Rizzoni D, Rotella C, Rubattu S, Salvetti G, Sarto P, Tassinari F, Trimarco B, de Kreutzenberg SV, Volpe R.

G Ital Cardiol (Rome). 2018 Feb;19(2 Suppl 1):1S-95S. doi: 10.1714/2874.28988. Italian.

PMID:
29531376
8.

Clinical and Molecular Aspects of Cardiomyopathies: Emerging Therapies and Clinical Trials.

Maurizi N, Ammirati E, Coppini R, Morrone A, Olivotto I.

Heart Fail Clin. 2018 Apr;14(2):161-178. doi: 10.1016/j.hfc.2018.01.001. Review. Erratum in: Heart Fail Clin. 2018 Jul;14(3):xvii.

PMID:
29525645
9.

Efficacy of Ranolazine in Patients With Symptomatic Hypertrophic Cardiomyopathy: The RESTYLE-HCM Randomized, Double-Blind, Placebo-Controlled Study.

Olivotto I, Camici PG, Merlini PA, Rapezzi C, Patten M, Climent V, Sinagra G, Tomberli B, Marin F, Ehlermann P, Maier LS, Fornaro A, Jacobshagen C, Ganau A, Moretti L, Hernandez Madrid A, Coppini R, Reggiardo G, Poggesi C, Fattirolli F, Belardinelli L, Gensini G, Mugelli A.

Circ Heart Fail. 2018 Jan;11(1):e004124. doi: 10.1161/CIRCHEARTFAILURE.117.004124.

PMID:
29321131
10.

Reply to Entcheva: The impact of T-tubules on action potential propagation in cardiac tissue.

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E562-E563. doi: 10.1073/pnas.1720253115. Epub 2018 Jan 5. No abstract available.

11.

Comparison of long-term outcome in anthracycline-related versus idiopathic dilated cardiomyopathy: a single centre experience.

Fornaro A, Olivotto I, Rigacci L, Ciaccheri M, Tomberli B, Ferrantini C, Coppini R, Girolami F, Mazzarotto F, Chiostri M, Milli M, Marchionni N, Castelli G.

Eur J Heart Fail. 2018 May;20(5):898-906. doi: 10.1002/ejhf.1049. Epub 2017 Nov 16.

PMID:
29148208
12.

Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy.

Zaglia T, Ceriotti P, Campo A, Borile G, Armani A, Carullo P, Prando V, Coppini R, Vida V, Stølen TO, Ulrik W, Cerbai E, Stellin G, Faggian G, De Stefani D, Sandri M, Rizzuto R, Di Lisa F, Pozzan T, Catalucci D, Mongillo M.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9006-E9015. doi: 10.1073/pnas.1708772114. Epub 2017 Oct 9.

13.

Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair.

Martella D, Paoli P, Pioner JM, Sacconi L, Coppini R, Santini L, Lulli M, Cerbai E, Wiersma DS, Poggesi C, Ferrantini C, Parmeggiani C.

Small. 2017 Dec;13(46). doi: 10.1002/smll.201702677. Epub 2017 Oct 17.

PMID:
29045016
14.

Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.

Ferrantini C, Coppini R, Pioner JM, Gentile F, Tosi B, Mazzoni L, Scellini B, Piroddi N, Laurino A, Santini L, Spinelli V, Sacconi L, De Tombe P, Moore R, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Tesi C, Poggesi C.

J Am Heart Assoc. 2017 Jul 22;6(7). pii: e005407. doi: 10.1161/JAHA.116.005407.

15.

Sodium-dependent glucose transporters (SGLT) in human ischemic heart: A new potential pharmacological target.

Di Franco A, Cantini G, Tani A, Coppini R, Zecchi-Orlandini S, Raimondi L, Luconi M, Mannucci E.

Int J Cardiol. 2017 Sep 15;243:86-90. doi: 10.1016/j.ijcard.2017.05.032. Epub 2017 May 9.

PMID:
28526540
16.

Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy.

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):5737-5742. doi: 10.1073/pnas.1702188114. Epub 2017 May 15.

17.

Effects of ranolazine in a model of doxorubicin-induced left ventricle diastolic dysfunction.

Cappetta D, Esposito G, Coppini R, Piegari E, Russo R, Ciuffreda LP, Rivellino A, Santini L, Rafaniello C, Scavone C, Rossi F, Berrino L, Urbanek K, De Angelis A.

Br J Pharmacol. 2017 Nov;174(21):3696-3712. doi: 10.1111/bph.13791. Epub 2017 May 16.

PMID:
28320043
18.

Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.

Coppini R, Mazzoni L, Ferrantini C, Gentile F, Pioner JM, Laurino A, Santini L, Bargelli V, Rotellini M, Bartolucci G, Crocini C, Sacconi L, Tesi C, Belardinelli L, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Poggesi C.

Circ Heart Fail. 2017 Mar;10(3). pii: e003565. doi: 10.1161/CIRCHEARTFAILURE.116.003565.

PMID:
28255011
19.

Electrical defects of the transverse-axial tubular system in cardiac diseases.

Crocini C, Ferrantini C, Coppini R, Sacconi L.

J Physiol. 2017 Jun 15;595(12):3815-3822. doi: 10.1113/JP273042. Epub 2017 Jan 17. Review.

20.

Role of quantitative myocardial positron emission tomography for risk stratification in patients with hypertrophic cardiomyopathy: a 2016 reappraisal.

Castagnoli H, Ferrantini C, Coppini R, Passeri A, Baldini K, Berti V, Cecchi F, Olivotto I, Sciagrà R.

Eur J Nucl Med Mol Imaging. 2016 Dec;43(13):2413-2422. Epub 2016 Aug 16.

PMID:
27527796
21.

Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation.

Crocini C, Ferrantini C, Coppini R, Scardigli M, Yan P, Loew LM, Smith G, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Sci Rep. 2016 Oct 17;6:35628. doi: 10.1038/srep35628.

22.

T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.

Crocini C, Coppini R, Ferrantini C, Yan P, Loew LM, Poggesi C, Cerbai E, Pavone FS, Sacconi L.

Int J Mol Sci. 2016 Sep 3;17(9). pii: E1471. doi: 10.3390/ijms17091471.

23.

Clinical research in neonates and infants: Challenges and perspectives.

Coppini R, Simons SHP, Mugelli A, Allegaert K.

Pharmacol Res. 2016 Jun;108:80-87. doi: 10.1016/j.phrs.2016.04.025. Epub 2016 Apr 30. Review.

PMID:
27142783
24.

Pharmacological treatment of hypertrophic cardiomyopathy: current practice and novel perspectives.

Ammirati E, Contri R, Coppini R, Cecchi F, Frigerio M, Olivotto I.

Eur J Heart Fail. 2016 Sep;18(9):1106-18. doi: 10.1002/ejhf.541. Epub 2016 Apr 24. Review.

25.

[Molecular targets and novel pharmacological options to prevent myocardial hypertrophic remodeling].

Coppini R, Ferrantini C, Poggesi C, Mugelli A, Olivotto I.

G Ital Cardiol (Rome). 2016 Mar;17(3):189-96. doi: 10.1714/2190.23660. Review. Italian.

PMID:
27029877
26.

Novel Approach Targeting the Complex Pathophysiology of Hypertrophic Cardiomyopathy: The Impact of Late Sodium Current Inhibition on Exercise Capacity in Subjects with Symptomatic Hypertrophic Cardiomyopathy (LIBERTY-HCM) Trial.

Olivotto I, Hellawell JL, Farzaneh-Far R, Blair C, Coppini R, Myers J, Belardinelli L, Maron MS.

Circ Heart Fail. 2016 Mar;9(3):e002764. doi: 10.1161/CIRCHEARTFAILURE.115.002764.

PMID:
26915375
27.

Impact of Genotype on the Occurrence of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy.

Bongini C, Ferrantini C, Girolami F, Coppini R, Arretini A, Targetti M, Bardi S, Castelli G, Torricelli F, Cecchi F, Ackerman MJ, Padeletti L, Poggesi C, Olivotto I.

Am J Cardiol. 2016 Apr 1;117(7):1151-9. doi: 10.1016/j.amjcard.2015.12.058. Epub 2016 Jan 14.

PMID:
26869393
28.

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

Crocini C, Ferrantini C, Scardigli M, Coppini R, Mazzoni L, Lazzeri E, Pioner JM, Scellini B, Guo A, Song LS, Yan P, Loew LM, Tardiff J, Tesi C, Vanzi F, Cerbai E, Pavone FS, Sacconi L, Poggesi C.

J Mol Cell Cardiol. 2016 Feb;91:42-51. doi: 10.1016/j.yjmcc.2015.12.013. Epub 2015 Dec 20.

29.

R4496C RyR2 mutation impairs atrial and ventricular contractility.

Ferrantini C, Coppini R, Scellini B, Ferrara C, Pioner JM, Mazzoni L, Priori S, Cerbai E, Tesi C, Poggesi C.

J Gen Physiol. 2016 Jan;147(1):39-52. doi: 10.1085/jgp.201511450. Epub 2015 Dec 14.

30.

Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy.

Passini E, Mincholé A, Coppini R, Cerbai E, Rodriguez B, Severi S, Bueno-Orovio A.

J Mol Cell Cardiol. 2016 Jul;96:72-81. doi: 10.1016/j.yjmcc.2015.09.003. Epub 2015 Sep 16.

31.

Targets for therapy in sarcomeric cardiomyopathies.

Tardiff JC, Carrier L, Bers DM, Poggesi C, Ferrantini C, Coppini R, Maier LS, Ashrafian H, Huke S, van der Velden J.

Cardiovasc Res. 2015 Apr 1;105(4):457-70. doi: 10.1093/cvr/cvv023. Epub 2015 Jan 29. Review.

32.

Clinical phenotype and outcome of hypertrophic cardiomyopathy associated with thin-filament gene mutations.

Coppini R, Ho CY, Ashley E, Day S, Ferrantini C, Girolami F, Tomberli B, Bardi S, Torricelli F, Cecchi F, Mugelli A, Poggesi C, Tardiff J, Olivotto I.

J Am Coll Cardiol. 2014 Dec 23;64(24):2589-2600. doi: 10.1016/j.jacc.2014.09.059.

33.

Functional cardiac imaging by random access microscopy.

Crocini C, Coppini R, Ferrantini C, Pavone FS, Sacconi L.

Front Physiol. 2014 Oct 20;5:403. doi: 10.3389/fphys.2014.00403. eCollection 2014.

34.

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure.

Crocini C, Coppini R, Ferrantini C, Yan P, Loew LM, Tesi C, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15196-201. doi: 10.1073/pnas.1411557111. Epub 2014 Oct 6.

35.

Impact of detubulation on force and kinetics of cardiac muscle contraction.

Ferrantini C, Coppini R, Sacconi L, Tosi B, Zhang ML, Wang GL, de Vries E, Hoppenbrouwers E, Pavone F, Cerbai E, Tesi C, Poggesi C, ter Keurs HE.

J Gen Physiol. 2014 Jun;143(6):783-97. doi: 10.1085/jgp.201311125.

36.

Isolation and functional characterization of human ventricular cardiomyocytes from fresh surgical samples.

Coppini R, Ferrantini C, Aiazzi A, Mazzoni L, Sartiani L, Mugelli A, Poggesi C, Cerbai E.

J Vis Exp. 2014 Apr 21;(86). doi: 10.3791/51116.

37.

Altered calcium regulation in isolated cardiomyocytes from Egr-1 knock-out mice.

Pacini L, Suffredini S, Ponti D, Coppini R, Frati G, Ragona G, Cerbai E, Calogero A.

Can J Physiol Pharmacol. 2013 Dec;91(12):1135-42. doi: 10.1139/cjpp-2012-0419. Epub 2013 Sep 5.

PMID:
24289086
38.

Response to letter regarding article, "Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy".

Coppini R, Ferrantini C, Del Lungo M, Stillitano F, Sartiani L, Tosi B, Suffredini S, Tesi C, Poggesi C, Cerbai E, Mugelli A, Yao L, Fan P, Belardinelli L, Yacoub M, Olivotto I.

Circulation. 2013 Sep 3;128(10):e157. doi: 10.1161/CIRCULATIONAHA.113.004016. No abstract available.

PMID:
24002721
39.

Chronic atrial fibrillation alters the functional properties of If in the human atrium.

Stillitano F, Lonardo G, Giunti G, Del Lungo M, Coppini R, Spinelli V, Sartiani L, Poggesi C, Mugelli A, Cerbai E.

J Cardiovasc Electrophysiol. 2013 Dec;24(12):1391-400. doi: 10.1111/jce.12212. Epub 2013 Jul 19.

PMID:
23869794
40.

The transverse-axial tubular system of cardiomyocytes.

Ferrantini C, Crocini C, Coppini R, Vanzi F, Tesi C, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Cell Mol Life Sci. 2013 Dec;70(24):4695-710. doi: 10.1007/s00018-013-1410-5. Epub 2013 Jul 12. Review.

PMID:
23846763
41.

Representativeness of the "Fiesole Misurata" study database for use in pharmaco-epidemiological investigations on adherence to antihypertensive medications.

Lapi F, Lucenteforte E, Moschini M, Bonaiuti R, Di Pirro M, Barchielli A, Benemei S, Belladonna M, Nesti N, Coppini R, Taras M, Vannacci A, Ungar A, Mugelli A.

Aging Clin Exp Res. 2013 Aug;25(4):433-45. doi: 10.1007/s40520-013-0060-7. Epub 2013 Jun 19.

PMID:
23780690
42.

UDP-glucose enhances outward K(+) currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors.

Coppi E, Maraula G, Fumagalli M, Failli P, Cellai L, Bonfanti E, Mazzoni L, Coppini R, Abbracchio MP, Pedata F, Pugliese AM.

Glia. 2013 Jul;61(7):1155-71. doi: 10.1002/glia.22506. Epub 2013 May 2.

PMID:
23640798
43.

Regulation of intracellular Na(+) in health and disease: pathophysiological mechanisms and implications for treatment.

Coppini R, Ferrantini C, Mazzoni L, Sartiani L, Olivotto I, Poggesi C, Cerbai E, Mugelli A.

Glob Cardiol Sci Pract. 2013 Nov 1;2013(3):222-42. doi: 10.5339/gcsp.2013.30. eCollection 2013. Review.

44.

Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy.

Coppini R, Ferrantini C, Yao L, Fan P, Del Lungo M, Stillitano F, Sartiani L, Tosi B, Suffredini S, Tesi C, Yacoub M, Olivotto I, Belardinelli L, Poggesi C, Cerbai E, Mugelli A.

Circulation. 2013 Feb 5;127(5):575-84. doi: 10.1161/CIRCULATIONAHA.112.134932. Epub 2012 Dec 27.

PMID:
23271797
45.

β Blockers for prevention of exercise-induced left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy.

Nistri S, Olivotto I, Maron MS, Ferrantini C, Coppini R, Grifoni C, Baldini K, Sgalambro A, Cecchi F, Maron BJ.

Am J Cardiol. 2012 Sep 1;110(5):715-9. doi: 10.1016/j.amjcard.2012.04.051. Epub 2012 May 24.

PMID:
22633205
46.

[Management of refractory symptoms in hypertrophic cardiomyopathy with restrictive pathophysiology: novel perspectives for ranolazine].

Tomberli B, Girolami F, Coppini R, Ferrantini C, Rossi A, Cecchi F, Olivotto I.

G Ital Cardiol (Rome). 2012 Apr;13(4):297-303. doi: 10.1714/1056.11562. Italian.

PMID:
22495647
47.

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

Sacconi L, Ferrantini C, Lotti J, Coppini R, Yan P, Loew LM, Tesi C, Cerbai E, Poggesi C, Pavone FS.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5815-9. doi: 10.1073/pnas.1120188109. Epub 2012 Mar 26.

48.

Comfort and satisfaction during axillary brachial plexus block in trauma patients: comparison of techniques.

Gianesello L, Pavoni V, Coppini R, Buoninsegni LT, Gori G, Mori E, Paparella L, Gritti G.

J Clin Anesth. 2010 Feb;22(1):7-12. doi: 10.1016/j.jclinane.2009.02.010.

PMID:
20206845
49.

Opioid-free analgesia by continuous psoas compartment block after total hip arthroplasty. A randomized study.

Becchi C, Al Malyan M, Coppini R, Campolo M, Magherini M, Boncinelli S.

Eur J Anaesthesiol. 2008 May;25(5):418-23. Epub 2007 Nov 21.

PMID:
18028577
50.

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