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Items: 12


Emerging Roles for Ciz1 in Cell Cycle Regulation and as a Driver of Tumorigenesis.

Pauzaite T, Thacker U, Tollitt J, Copeland NA.

Biomolecules. 2016 Dec 27;7(1). pii: E1. doi: 10.3390/biom7010001. Review.


NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes.

Marriott AS, Vasieva O, Fang Y, Copeland NA, McLennan AG, Jones NJ.

PLoS One. 2016 May 4;11(5):e0154674. doi: 10.1371/journal.pone.0154674. eCollection 2016.


Diadenosine 5', 5'''-P(1),P(4)-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication.

Marriott AS, Copeland NA, Cunningham R, Wilkinson MC, McLennan AG, Jones NJ.

DNA Repair (Amst). 2015 Sep;33:90-100. doi: 10.1016/j.dnarep.2015.06.008. Epub 2015 Jun 29.


Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria.

Rassam P, Copeland NA, Birkholz O, Tóth C, Chavent M, Duncan AL, Cross SJ, Housden NG, Kaminska R, Seger U, Quinn DM, Garrod TJ, Sansom MS, Piehler J, Baumann CG, Kleanthous C.

Nature. 2015 Jul 16;523(7560):333-6. doi: 10.1038/nature14461. Epub 2015 Jun 10.


Cyclin-A-CDK2-mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication.

Copeland NA, Sercombe HE, Wilson RH, Coverley D.

J Cell Sci. 2015 Apr 15;128(8):1518-27. doi: 10.1242/jcs.161919. Epub 2015 Mar 3.


Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cells.

Greaves EA, Copeland NA, Coverley D, Ainscough JF.

J Cell Sci. 2012 May 15;125(Pt 10):2466-77. doi: 10.1242/jcs.101097. Epub 2012 Feb 24.


Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.

Munkley J, Copeland NA, Moignard V, Knight JR, Greaves E, Ramsbottom SA, Pownall ME, Southgate J, Ainscough JF, Coverley D.

Nucleic Acids Res. 2011 Apr;39(7):2671-7. doi: 10.1093/nar/gkq1190. Epub 2010 Nov 24.


Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro.

Copeland NA, Sercombe HE, Ainscough JF, Coverley D.

J Cell Sci. 2010 Apr 1;123(Pt 7):1108-15. doi: 10.1242/jcs.059345. Epub 2010 Mar 9.


Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia.

Wang DH, Clemons NJ, Miyashita T, Dupuy AJ, Zhang W, Szczepny A, Corcoran-Schwartz IM, Wilburn DL, Montgomery EA, Wang JS, Jenkins NA, Copeland NA, Harmon JW, Phillips WA, Watkins DN.

Gastroenterology. 2010 May;138(5):1810-22. doi: 10.1053/j.gastro.2010.01.048. Epub 2010 Feb 4.


The role of an activating peptide in protease-mediated suicide of Escherichia coli K12.

Copeland NA, Kleanthous C.

J Biol Chem. 2005 Jan 7;280(1):112-7. Epub 2004 Oct 22.


Identification of essential residues within Lit, a cell death peptidase of Escherichia coli K-12.

Copeland NA, Bingham R, Georgiou T, Cooper P, Kleanthous C.

Biochemistry. 2004 Jun 22;43(24):7948-53.


The Nab2 and Stat6 genes share a common transcription termination region.

Svaren J, Apel ED, Simburger KS, Jenkins NA, Gilbert DJ, Copeland NA, Milbrandt J.

Genomics. 1997 Apr 1;41(1):33-9.


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