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Items: 1 to 50 of 736

1.

Clinical Pig Kidney Xenotransplantation: How Close Are We?

Cooper DKC, Hara H, Iwase H, Yamamoto T, Jagdale A, Kumar V, Mannon RB, Hanaway MJ, Anderson DJ, Eckhoff DE.

J Am Soc Nephrol. 2019 Dec 2. pii: ASN.2019070651. doi: 10.1681/ASN.2019070651. [Epub ahead of print]

PMID:
31792154
2.

IS IL-6 Receptor blockade (Tocilizumab) beneficial or detrimental to pig-to-baboon organ Xenotransplantation?

Zhang G, Iwase H, Wang L, Yamamoto T, Jagdale A, Ayares D, Li Y, Cooper DKC, Hara H.

Am J Transplant. 2019 Nov 16. doi: 10.1111/ajt.15712. [Epub ahead of print]

PMID:
31733178
3.

Selective inhibition of cyclooxygenase-2 protects porcine aortic endothelial cells from human antibody-mediated complement-dependent cytotoxicity.

Chen P, Zhao Y, Gao H, Huang J, Lu Y, Song J, Lin L, Lin Z, Ou C, Sun H, Li Y, Zeng C, Cooper DKC, Zhan Y, Deng X, Mou L.

Xenotransplantation. 2019 Nov 14:e12536. doi: 10.1111/xen.12536. [Epub ahead of print]

PMID:
31724835
4.

Paediatric xenotransplantation clinical trials and the right to withdraw.

Hurst DJ, Padilla LA, Walters W, Hunter JM, Cooper DKC, Eckhoff DM, Cleveland D, Paris W.

J Med Ethics. 2019 Nov 8. pii: medethics-2019-105668. doi: 10.1136/medethics-2019-105668. [Epub ahead of print]

PMID:
31704780
5.

Decellularization methods for developing porcine corneal xenografts and future perspectives.

Isidan A, Liu S, Li P, Lashmet M, Smith LJ, Hara H, Cooper DKC, Ekser B.

Xenotransplantation. 2019 Oct 28:e12564. doi: 10.1111/xen.12564. [Epub ahead of print] Review.

PMID:
31659811
6.

ANTI-PIG ANTIBODY IN INFANTS: CAN A GENETICALLY-ENGINEERED PIG HEART BRIDGE TO ALLOTRANSPLANTATION?

Li Q, Hara H, Banks CA, Yamamoto T, Ayares D, Mauchley DC, Dabal RJ, Padilla L, Carlo WF, Rhodes LA, Cooper DKC, Cleveland DC.

Ann Thorac Surg. 2019 Sep 30. pii: S0003-4975(19)31452-3. doi: 10.1016/j.athoracsur.2019.08.061. [Epub ahead of print]

PMID:
31580857
7.

Isolation and Culture of Primary Aortic Endothelial Cells from Miniature Pigs.

Zhao Y, Zhao C, Cooper DKC, Lu Y, Luo K, Wang H, Chen P, Zeng C, Luan S, Mou L, Gao H.

J Vis Exp. 2019 Aug 14;(150). doi: 10.3791/59673.

PMID:
31475978
8.

Human CTLA4-Ig therapy can give false-positive anti-pig antibody results in primates after xenotransplantation.

Li Q, Yamamoto T, Iwase H, Nguyen HQ, Wang Y, Ayares D, Cooper DKC, Hara H.

Transpl Immunol. 2019 Dec;57:101243. doi: 10.1016/j.trim.2019.101243. Epub 2019 Aug 28.

PMID:
31472231
9.

Indicators of impending pig kidney and heart xenograft failure: Relevance to clinical organ xenotransplantation - Review article.

Iwase H, Jagdale A, Yamamoto T, Zhang G, Li Q, Foote J, Ayares D, Ekser B, Hara H, Cooper DKC.

Int J Surg. 2019 Oct;70:84-91. doi: 10.1016/j.ijsu.2019.08.024. Epub 2019 Aug 21. Review.

PMID:
31445094
10.

Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cells.

Xie C, Qu Z, Hara H, Dai W, Wang X, Pan D, Zhou M, Dai Y, Cai Z, Zhang J, Cooper DKC, Mou L.

Xenotransplantation. 2019 Aug 21:e12537. doi: 10.1111/xen.12537. [Epub ahead of print]

PMID:
31433094
11.

The potential role of 3D-bioprinting in xenotransplantation.

Li P, Zhang W, Smith LJ, Ayares D, Cooper DKC, Ekser B.

Curr Opin Organ Transplant. 2019 Oct;24(5):547-554. doi: 10.1097/MOT.0000000000000684.

12.

Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review article.

Smood B, Bottino R, Hara H, Cooper DKC.

Int J Surg. 2019 Sep;69:100-107. doi: 10.1016/j.ijsu.2019.07.032. Epub 2019 Jul 30. Review.

PMID:
31369877
13.

TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression.

Gao H, Cao M, Chen P, Cooper DKC, Zhao Y, Wei L, Xu J, Cai Z, Zeng C, Luan S, Mou L.

Cell Commun Signal. 2019 Jul 15;17(1):75. doi: 10.1186/s12964-019-0386-7.

14.

Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive Regimens.

Yamamoto T, Hara H, Foote J, Wang L, Li Q, Klein EC, Schuurman HJ, Zhou H, Li J, Tector AJ, Zhang Z, Ezzelarab M, Lovingood R, Ayares D, Eckhoff DE, Cooper DKC, Iwase H.

Transplantation. 2019 Oct;103(10):2090-2104. doi: 10.1097/TP.0000000000002796.

PMID:
31283686
15.

Evidence for the important role of inflammation in xenotransplantation.

Li J, Hara H, Wang Y, Esmon C, Cooper DKC, Iwase H.

J Inflamm (Lond). 2019 May 28;16:10. doi: 10.1186/s12950-019-0213-3. eCollection 2019. Review.

16.

A potential role of TLR2 in xenograft rejection of porcine iliac endothelial cells: An in vitro study.

Chen J, Gao H, Chen L, Wang X, Song Z, Cooper DKC, Qu Z, Cai Z, Mou L.

Xenotransplantation. 2019 Sep;26(5):e12526. doi: 10.1111/xen.12526. Epub 2019 May 24.

PMID:
31127671
17.

Circulating pig-specific DNA as a novel biomarker for monitoring xenograft rejection.

Zhou M, Lu Y, Zhao C, Zhang J, Cooper DKC, Xie C, Song Z, Gao H, Qu Z, Lin S, Deng Y, Hara H, Zhan Y, Jiang Z, Dai Y, Wu C, Cai Z, Mou L.

Xenotransplantation. 2019 Jul;26(4):e12522. doi: 10.1111/xen.12522. Epub 2019 May 11.

PMID:
31077480
18.

The complex functioning of the complement system in xenotransplantation.

Zhou H, Hara H, Cooper DKC.

Xenotransplantation. 2019 Jul;26(4):e12517. doi: 10.1111/xen.12517. Epub 2019 Apr 29. Review.

19.

Justification of specific genetic modifications in pigs for clinical organ xenotransplantation.

Cooper DKC, Hara H, Iwase H, Yamamoto T, Li Q, Ezzelarab M, Federzoni E, Dandro A, Ayares D.

Xenotransplantation. 2019 Jul;26(4):e12516. doi: 10.1111/xen.12516. Epub 2019 Apr 15.

PMID:
30989742
20.

The "Baby Fae" baboon heart transplant-Potential cause of rejection.

Cooper DKC, Hara H, Banks CA, Cleveland D, Iwase H.

Xenotransplantation. 2019 Jul;26(4):e12511. doi: 10.1111/xen.12511. Epub 2019 Apr 1. No abstract available.

21.

Incidence of Neoplasia in Pigs and Its Relevance to Clinical Organ Xenotransplantation.

Jagdale A, Iwase H, Klein EC, Cooper DK.

Comp Med. 2019 Apr 1;69(2):86-94. doi: 10.30802/AALAS-CM-18-000093. Epub 2019 Mar 25.

22.

In Search of the Ideal Valve: Optimizing Genetic Modifications to Prevent Bioprosthetic Degeneration.

Smood B, Hara H, Cleveland DC, Cooper DKC.

Ann Thorac Surg. 2019 Aug;108(2):624-635. doi: 10.1016/j.athoracsur.2019.01.054. Epub 2019 Mar 2. Review.

PMID:
30836101
23.

Latinx Mental Health Scholars' Experiences with Cultural Adaptation and Implementation of Systemic Family Interventions.

Cooper DK, Wieling E, Domenech Rodríguez MM, Garcia-Huidobro D, Baumann A, Mejia A, Le HN, Cardemil EV, Acevedo-Polakovich ID.

Fam Process. 2019 Mar 4. doi: 10.1111/famp.12433. [Epub ahead of print]

PMID:
30830697
24.

Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantation.

Zhao Y, Cooper DKC, Wang H, Chen P, He C, Cai Z, Mou L, Luan S, Gao H.

Xenotransplantation. 2019 May;26(3):e12502. doi: 10.1111/xen.12502. Epub 2019 Feb 16. Review.

PMID:
30770591
25.

Carbohydrate antigen expression and anti-pig antibodies in New World capuchin monkeys: Relevance to studies of xenotransplantation.

Li Q, Shaikh S, Iwase H, Long C, Lee W, Zhang Z, Wang Y, Ayares D, Cooper DKC, Hara H.

Xenotransplantation. 2019 May;26(3):e12498. doi: 10.1111/xen.12498. Epub 2019 Feb 16.

PMID:
30770572
26.

A review of pig liver xenotransplantation: Current problems and recent progress.

Zhang X, Li X, Yang Z, Tao K, Wang Q, Dai B, Qu S, Peng W, Zhang H, Cooper DKC, Dou K.

Xenotransplantation. 2019 May;26(3):e12497. doi: 10.1111/xen.12497. Epub 2019 Feb 15. Review.

PMID:
30767272
27.

Genetically-engineered pigs as sources for clinical red blood cell transfusion: What pathobiological barriers need to be overcome?

Smood B, Hara H, Schoel LJ, Cooper DKC.

Blood Rev. 2019 May;35:7-17. doi: 10.1016/j.blre.2019.01.003. Epub 2019 Jan 28. Review.

PMID:
30711308
28.

A Method for Islet Transplantation to the Omentum in Mouse.

Lu Y, Zou S, Bertera S, Bottino R, Cooper DKC, Liu Z, Huang Y, Wang C, Hong C, He T, Zhang H, Huo Q, Fu H, Cai Z, Mou L.

J Vis Exp. 2019 Jan 7;(143). doi: 10.3791/57160.

PMID:
30663661
29.

Life-supporting porcine cardiac xenotransplantation: The Munich study.

Cooper DKC, Iwase H, Yamamoto T, Hara H.

Xenotransplantation. 2019 May;26(3):e12486. doi: 10.1111/xen.12486. Epub 2019 Jan 18. No abstract available.

30.

Financial support for xenotransplantation research.

Cooper DKC.

Xenotransplantation. 2019 May;26(3):e12483. doi: 10.1111/xen.12483. Epub 2019 Jan 3. No abstract available.

31.

Serum amyloid a as an indicator of impending xenograft failure: Experimental studies.

Zhang G, Hara H, Yamamoto T, Li Q, Jagdale A, Li Y, Cooper DKC, Iwase H.

Int J Surg. 2018 Dec;60:283-290. doi: 10.1016/j.ijsu.2018.11.027. Epub 2018 Dec 3.

32.

Episodes of hypovolemia/dehydration in baboons with pig kidney transplants: A new syndrome of clinical importance?

Iwase H, Yamamoto T, Cooper DKC.

Xenotransplantation. 2019 Mar;26(2):e12472. doi: 10.1111/xen.12472. Epub 2018 Nov 28. No abstract available.

PMID:
30485551
33.

Experimental Pig Heart Xenotransplantation-Recent Progress and Remaining Problems.

Cooper DKC.

Ann Thorac Surg. 2019 Apr;107(4):989-992. doi: 10.1016/j.athoracsur.2018.09.074. Epub 2018 Nov 22. No abstract available.

PMID:
30471272
34.

Chronic dialysis in patients with end-stage renal disease: Relevance to kidney xenotransplantation.

Jagdale A, Cooper DKC, Iwase H, Gaston RS.

Xenotransplantation. 2019 Mar;26(2):e12471. doi: 10.1111/xen.12471. Epub 2018 Nov 20.

PMID:
30456901
35.

Will donor-derived neoplasia be problematic after clinical pig organ or cell xenotransplantation?

Jagdale A, Iwase H, Klein E, Cooper DKC.

Xenotransplantation. 2019 Mar;26(2):e12469. doi: 10.1111/xen.12469. Epub 2018 Nov 9.

PMID:
30411396
36.

The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome?

Cleveland D, Adam Banks C, Hara H, Carlo WF, Mauchley DC, Cooper DKC.

Pediatr Cardiol. 2019 Feb;40(2):437-444. doi: 10.1007/s00246-018-1998-1. Epub 2018 Oct 9. Review.

PMID:
30302505
37.

Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.

Yamamoto T, Li Q, Hara H, Wang L, Zhou H, Li J, Eckhoff DE, Tector AJ, Klein EC, Lovingood R, Ezzelarab M, Ayares D, Wang Y, Cooper DKC, Iwase H.

Data Brief. 2018 Sep 13;20:1965-1974. doi: 10.1016/j.dib.2018.08.213. eCollection 2018 Oct.

38.

Perspectives on the Optimal Genetically Engineered Pig in 2018 for Initial Clinical Trials of Kidney or Heart Xenotransplantation.

Cooper DKC, Ezzelarab M, Iwase H, Hara H.

Transplantation. 2018 Dec;102(12):1974-1982. doi: 10.1097/TP.0000000000002443. Review.

39.

Xenotransplantation research and the 'International Journal of Surgery'.

Ekser B, Cooper DKC.

Int J Surg. 2018 Oct;58:57-59. doi: 10.1016/j.ijsu.2018.09.006. Epub 2018 Sep 17. No abstract available.

PMID:
30237083
40.

Physiologic Aspects of Pig Kidney Transplantation in Nonhuman Primates.

Iwase H, Klein EC, Cooper DK.

Comp Med. 2018 Oct 1;68(5):332-340. doi: 10.30802/AALAS-CM-17-000117. Epub 2018 Sep 12. Review.

41.

An approach to induction of tolerance to pig cardiac xenografts in neonates.

Cooper DKC, Hara H, Iwase H, Banks CA, Cleveland DC.

Xenotransplantation. 2018 Nov;25(6):e12454. doi: 10.1111/xen.12454. Epub 2018 Aug 20. Review.

PMID:
30125392
42.

B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.

Yamamoto T, Li Q, Hara H, Wang L, Zhou H, Li J, Eckhoff DE, Joseph Tector A, Klein EC, Lovingood R, Ezzelarab M, Ayares D, Wang Y, Cooper DKC, Iwase H.

Transpl Immunol. 2018 Dec;51:12-20. doi: 10.1016/j.trim.2018.08.005. Epub 2018 Aug 6.

43.

Christiaan Barnard-The surgeon who dared: The story of the first human-to-human heart transplant.

Cooper DKC.

Glob Cardiol Sci Pract. 2018 Jun 30;2018(2):11. doi: 10.21542/gcsp.2018.11. Review.

44.

Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of Xenografts.

Liu L, He C, Liu J, Lv Z, Wang G, Gao H, Dai Y, Cooper DKC, Cai Z, Mou L.

Arch Immunol Ther Exp (Warsz). 2018 Oct;66(5):355-364. doi: 10.1007/s00005-018-0517-7. Epub 2018 Jul 10. Review.

PMID:
29992337
45.

Porcine IL-6, IL-1β, and TNF-α regulate the expression of pro-inflammatory-related genes and tissue factor in human umbilical vein endothelial cells.

Gao H, Zhang Q, Chen J, Cooper DKC, Hara H, Chen P, Wei L, Zhao Y, Xu J, Li Z, Cai Z, Luan S, Mou L.

Xenotransplantation. 2018 Sep;25(5):e12408. doi: 10.1111/xen.12408. Epub 2018 Jun 22.

PMID:
29932258
46.

20th Anniversary of IXA, 1998-2018.

Cooper DKC, Buhler LH.

Xenotransplantation. 2018 May;25(3):e12425. doi: 10.1111/xen.12425. No abstract available.

47.

Corrigendum to "The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation".

Samy KP, Butler JR, Li P, Cooper DKC, Ekser B.

J Immunol Res. 2018 Mar 22;2018:6343608. doi: 10.1155/2018/6343608. eCollection 2018.

48.

Expression and Regulation Profile of Mature MicroRNA in the Pig: Relevance to Xenotransplantation.

Song Z, Cooper DKC, Cai Z, Mou L.

Biomed Res Int. 2018 Mar 21;2018:2983908. doi: 10.1155/2018/2983908. eCollection 2018. Review.

49.

Jewish, Christian and Muslim theological perspectives about xenotransplantation.

Paris W, Seidler RJH, FitzGerald K, Padela AI, Cozzi E, Cooper DKC.

Xenotransplantation. 2018 May;25(3):e12400. doi: 10.1111/xen.12400. Epub 2018 Apr 24.

PMID:
29687920
50.

Is sensitization to pig antigens detrimental to subsequent allotransplantation?

Li Q, Hara H, Zhang Z, Breimer ME, Wang Y, Cooper DKC.

Xenotransplantation. 2018 May;25(3):e12393. doi: 10.1111/xen.12393. Epub 2018 Apr 14. Review.

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