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Items: 1 to 50 of 91

1.

Generation of integration-free induced pluripotent stem cells from a patient with spina bifida.

Wang H, Zhao S, Finnell RH, George T, Cooney AJ.

Stem Cell Res. 2018 Aug;31:27-30. doi: 10.1016/j.scr.2018.05.007. Epub 2018 May 17.

2.

Reciprocity of Action of Increasing Oct4 and Repressing p53 in Transdifferentiation of Mouse Embryonic Fibroblasts into Cardiac Myocytes.

Wang H, Zhao S, Barton M, Rosengart T, Cooney AJ.

Cell Reprogram. 2018 Feb;20(1):27-37. doi: 10.1089/cell.2017.0031.

3.

Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice.

Lan ZJ, Krause MS, Redding SD, Li X, Wu GZ, Zhou HX, Bohler HC, Ko C, Cooney AJ, Zhou J, Lei ZM.

Mol Cell Endocrinol. 2017 Mar 15;444:26-37. doi: 10.1016/j.mce.2017.01.043. Epub 2017 Jan 28.

PMID:
28137614
4.

miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification.

Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, Liu Y.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9551-6. doi: 10.1073/pnas.1608256113. Epub 2016 Aug 10.

5.

GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells.

Lan ZJ, Hu Y, Zhang S, Li X, Zhou H, Ding J, Klinge CM, Radde BN, Cooney AJ, Zhang J, Lei Z.

Breast Cancer Res Treat. 2016 Jul;158(2):263-76. doi: 10.1007/s10549-016-3880-2. Epub 2016 Jun 29.

PMID:
27357812
6.

Generation of electrophysiologically functional cardiomyocytes from mouse induced pluripotent stem cells.

Wang H, Xi Y, Zheng Y, Wang X, Cooney AJ.

Stem Cell Res. 2016 Mar;16(2):522-30. doi: 10.1016/j.scr.2016.02.032. Epub 2016 Feb 23.

7.

Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells.

Wang H, Wang X, Xu X, Kyba M, Cooney AJ.

J Biol Chem. 2016 Apr 15;291(16):8644-52. doi: 10.1074/jbc.M115.694208. Epub 2016 Jan 14.

8.

Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.

Li S, Moore AK, Zhu J, Li X, Zhou H, Lin J, He Y, Xing F, Pan Y, Bohler HC, Ding J, Cooney AJ, Lan Z, Lei Z.

Biol Reprod. 2016 Feb;94(2):41. doi: 10.1095/biolreprod.115.136358. Epub 2016 Jan 13.

9.

Genome-Wide Identification of MESP1 Targets Demonstrates Primary Regulation Over Mesendoderm Gene Activity.

Soibam B, Benham A, Kim J, Weng KC, Yang L, Xu X, Robertson M, Azares A, Cooney AJ, Schwartz RJ, Liu Y.

Stem Cells. 2015 Nov;33(11):3254-65. doi: 10.1002/stem.2111. Epub 2015 Aug 18.

10.

Corrigendum: Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming.

Hirsch CL, Akdemir ZC, Wang L, Jayakumaran G, Trcka D, Weiss A, Hernandez JJ, Pan Q, Han H, Xu X, Xia Z, Salinger AP, Wilson M, Vizeacoumar F, Datti A, Li W, Cooney AJ, Barton MC, Blencowe BJ, Wrana JL, Dent SY.

Genes Dev. 2015 Jun 15;29(12):1341. doi: 10.1101/gad.266601.115. No abstract available.

11.

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming.

Hirsch CL, Coban Akdemir Z, Wang L, Jayakumaran G, Trcka D, Weiss A, Hernandez JJ, Pan Q, Han H, Xu X, Xia Z, Salinger AP, Wilson M, Vizeacoumar F, Datti A, Li W, Cooney AJ, Barton MC, Blencowe BJ, Wrana JL, Dent SY.

Genes Dev. 2015 Apr 15;29(8):803-16. doi: 10.1101/gad.255109.114. Epub 2015 Apr 15. Erratum in: Genes Dev. 2015 Jun 15;29(12):1341.

12.

Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells.

Liu L, Liu L, Leung LH, Cooney AJ, Chen C, Rosengart TK, Ma Y, Yang J.

J Biol Chem. 2015 Apr 24;290(17):10599-609. doi: 10.1074/jbc.M114.634790. Epub 2015 Mar 3.

13.

Sox2 is the faithful marker for pluripotency in pig: evidence from embryonic studies.

Liu S, Bou G, Sun R, Guo S, Xue B, Wei R, Cooney AJ, Liu Z.

Dev Dyn. 2015 Apr;244(4):619-27. doi: 10.1002/dvdy.24248. Epub 2015 Jan 24.

14.

Germ cell nuclear factor regulates gametogenesis in developing gonads.

Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Araúzo-Bravo MJ, Gentile L, Greber B, Hübner K, Sebastiano V, Wu G, Schöler HR, Cooney AJ.

PLoS One. 2014 Aug 20;9(8):e103985. doi: 10.1371/journal.pone.0103985. eCollection 2014.

15.

GCNF-dependent activation of cyclin D1 expression via repression of Mir302a during ESC differentiation.

Wang H, Wang X, Archer TK, Zwaka TP, Cooney AJ.

Stem Cells. 2014 Jun;32(6):1527-37. doi: 10.1002/stem.1689.

16.

Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8.

Chakravarti D, Su X, Cho MS, Bui NH, Coarfa C, Venkatanarayan A, Benham AL, Flores González RE, Alana J, Xiao W, Leung ML, Vin H, Chan IL, Aquino A, Müller N, Wang H, Cooney AJ, Parker-Thornburg J, Tsai KY, Gunaratne PH, Flores ER.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):E572-81. doi: 10.1073/pnas.1319743111. Epub 2014 Jan 21.

17.

Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells.

Akdemir KC, Jain AK, Allton K, Aronow B, Xu X, Cooney AJ, Li W, Barton MC.

Nucleic Acids Res. 2014 Jan;42(1):205-23. doi: 10.1093/nar/gkt866. Epub 2013 Sep 27.

18.

Chromatin changes in dicer-deficient mouse embryonic stem cells in response to retinoic acid induced differentiation.

Tennakoon JB, Wang H, Coarfa C, Cooney AJ, Gunaratne PH.

PLoS One. 2013 Sep 9;8(9):e74556. doi: 10.1371/journal.pone.0074556. eCollection 2013.

19.

Revisiting the role of GCNF in embryonic development.

Wang Q, Cooney AJ.

Semin Cell Dev Biol. 2013 Dec;24(10-12):679-86. doi: 10.1016/j.semcdb.2013.08.003. Epub 2013 Sep 9. Review.

PMID:
24029702
20.

Role of LIN28A in mouse and human trophoblast cell differentiation.

Seabrook JL, Cantlon JD, Cooney AJ, McWhorter EE, Fromme BA, Bouma GJ, Anthony RV, Winger QA.

Biol Reprod. 2013 Oct 24;89(4):95. doi: 10.1095/biolreprod.113.109868. Print 2013 Oct.

21.

Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation.

Mahendram S, Kelly KF, Paez-Parent S, Mahmood S, Polena E, Cooney AJ, Doble BW.

PLoS One. 2013 May 27;8(5):e65320. doi: 10.1371/journal.pone.0065320. Print 2013.

22.

The role of nuclear receptors in embryonic stem cells.

Wang Q, Cooney AJ.

Adv Exp Med Biol. 2013;786:287-306. doi: 10.1007/978-94-007-6621-1_16. Review.

PMID:
23696363
23.

Regulatable in vivo biotinylation expression system in mouse embryonic stem cells.

Wang Q, Wagner RT, Cooney AJ.

PLoS One. 2013 May 7;8(5):e63532. doi: 10.1371/journal.pone.0063532. Print 2013.

24.

Minireview: the diverse roles of nuclear receptors in the regulation of embryonic stem cell pluripotency.

Wagner RT, Cooney AJ.

Mol Endocrinol. 2013 Jun;27(6):864-78. doi: 10.1210/me.2012-1383. Epub 2013 Mar 15. Review.

25.

Epigenetic reprogramming of the germ cell nuclear factor gene is required for proper differentiation of induced pluripotent cells.

Wang H, Wang X, Xu X, Zwaka TP, Cooney AJ.

Stem Cells. 2013 Dec;31(12):2659-66. doi: 10.1002/stem.1367.

26.

Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element.

Li Y, Yu W, Cooney AJ, Schwartz RJ, Liu Y.

Stem Cells. 2013 Jun;31(6):1213-7. doi: 10.1002/stem.1362.

27.

Transcriptomine, a web resource for nuclear receptor signaling transcriptomes.

Ochsner SA, Watkins CM, McOwiti A, Xu X, Darlington YF, Dehart MD, Cooney AJ, Steffen DL, Becnel LB, McKenna NJ.

Physiol Genomics. 2012 Sep 1;44(17):853-63. doi: 10.1152/physiolgenomics.00033.2012. Epub 2012 Jul 10.

28.

Comparison of 7α-methyl-19-nortestosterone effectiveness alone or combined with progestins on androgen receptor mediated-transactivation.

García-Becerra R, Ordaz-Rosado D, Noé G, Chávez B, Cooney AJ, Larrea F.

Reproduction. 2012 Feb;143(2):211-9. doi: 10.1530/REP-11-0171. Epub 2011 Nov 7.

PMID:
22065861
29.

miRNA regulatory circuits in ES cells differentiation: a chemical kinetics modeling approach.

Luo Z, Xu X, Gu P, Lonard D, Gunaratne PH, Cooney AJ, Azencott R.

PLoS One. 2011;6(10):e23263. doi: 10.1371/journal.pone.0023263. Epub 2011 Oct 19.

31.

Generation of viable male and female mice from two fathers.

Deng JM, Satoh K, Wang H, Chang H, Zhang Z, Stewart MD, Cooney AJ, Behringer RR.

Biol Reprod. 2011 Mar;84(3):613-8. doi: 10.1095/biolreprod.110.088831. Epub 2010 Dec 8.

32.

Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression.

Wagner RT, Xu X, Yi F, Merrill BJ, Cooney AJ.

Stem Cells. 2010 Oct;28(10):1794-804. doi: 10.1002/stem.502.

33.

Genomic action of permanently charged tamoxifen derivatives via estrogen receptor-alpha.

Rivera-Guevara C, Pérez-Alvarez V, García-Becerra R, Ordaz-Rosado D, Morales-Ríos MS, Hernández-Gallegos E, Cooney AJ, Bravo-Gómez ME, Larrea F, Camacho J.

Bioorg Med Chem. 2010 Aug 1;18(15):5593-601. doi: 10.1016/j.bmc.2010.06.039. Epub 2010 Jun 20.

PMID:
20621492
34.

Ligand-induced large-scale chromatin dynamics as a biosensor for the detection of estrogen receptor subtype selective ligands.

García-Becerra R, Berno V, Ordaz-Rosado D, Sharp ZD, Cooney AJ, Mancini MA, Larrea F.

Gene. 2010 Jun 15;458(1-2):37-44. doi: 10.1016/j.gene.2010.03.007. Epub 2010 Mar 24.

PMID:
20347019
35.

Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation.

Uhlenhaut NH, Jakob S, Anlag K, Eisenberger T, Sekido R, Kress J, Treier AC, Klugmann C, Klasen C, Holter NI, Riethmacher D, Schütz G, Cooney AJ, Lovell-Badge R, Treier M.

Cell. 2009 Dec 11;139(6):1130-42. doi: 10.1016/j.cell.2009.11.021.

36.

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles.

Adhikari D, Zheng W, Shen Y, Gorre N, Hämäläinen T, Cooney AJ, Huhtaniemi I, Lan ZJ, Liu K.

Hum Mol Genet. 2010 Feb 1;19(3):397-410. doi: 10.1093/hmg/ddp483. Epub 2009 Oct 20.

37.

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.

McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW.

Mol Endocrinol. 2009 Jun;23(6):740-6. doi: 10.1210/me.2009-0135. Epub 2009 May 7. Review. Erratum in: Mol Endocrinol. 2009 Sep;23(9):1522.

38.

OCT4: less is more.

Wagner RT, Cooney AJ.

Cell Res. 2009 May;19(5):527-8. doi: 10.1038/cr.2009.48. No abstract available.

PMID:
19421239
39.

Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression.

Gu P, Le Menuet D, Chung AC, Cooney AJ.

Mol Cell Biol. 2009 Apr;29(7):1987. doi: 10.1128/MCB.00019-09. No abstract available.

40.

Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage.

Akamatsu W, DeVeale B, Okano H, Cooney AJ, van der Kooy D.

J Neurosci. 2009 Feb 18;29(7):2113-24. doi: 10.1523/JNEUROSCI.4527-08.2009.

41.

Extra-germ cell expression of mouse nuclear receptor subfamily 6, group A, member 1 (NR6A1).

Lan ZJ, Xu X, Chung AC, Cooney AJ.

Biol Reprod. 2009 May;80(5):905-12. doi: 10.1095/biolreprod.107.067322. Epub 2009 Jan 21.

42.

Preimplantation mouse embryos depend on inhibitory phosphorylation of separase to prevent chromosome missegregation.

Huang X, Andreu-Vieyra CV, Wang M, Cooney AJ, Matzuk MM, Zhang P.

Mol Cell Biol. 2009 Mar;29(6):1498-505. doi: 10.1128/MCB.01778-08. Epub 2009 Jan 5.

43.

Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells.

Gu P, Reid JG, Gao X, Shaw CA, Creighton C, Tran PL, Zhou X, Drabek RB, Steffen DL, Hoang DM, Weiss MK, Naghavi AO, El-daye J, Khan MF, Legge GB, Wheeler DA, Gibbs RA, Miller JN, Cooney AJ, Gunaratne PH.

PLoS One. 2008 Jul 2;3(7):e2548. doi: 10.1371/journal.pone.0002548.

44.

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.

Liang J, Wan M, Zhang Y, Gu P, Xin H, Jung SY, Qin J, Wong J, Cooney AJ, Liu D, Songyang Z.

Nat Cell Biol. 2008 Jun;10(6):731-9. doi: 10.1038/ncb1736. Epub 2008 May 4.

PMID:
18454139
45.

Nuclear Receptors in Regulation of Mouse ES Cell Pluripotency and Differentiation.

Mullen EM, Gu P, Cooney AJ.

PPAR Res. 2007;2007:61563. doi: 10.1155/2007/61563.

46.

Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool.

Reddy P, Liu L, Adhikari D, Jagarlamudi K, Rajareddy S, Shen Y, Du C, Tang W, Hämäläinen T, Peng SL, Lan ZJ, Cooney AJ, Huhtaniemi I, Liu K.

Science. 2008 Feb 1;319(5863):611-3. doi: 10.1126/science.1152257.

47.

Orphan nuclear receptor function in the ovary.

Zhao H, Li Z, Cooney AJ, Lan ZJ.

Front Biosci. 2007 May 1;12:3398-405. Review.

PMID:
17485308
49.

Synthetic 19-nortestosterone derivatives as estrogen receptor alpha subtype-selective ligands induce similar receptor conformational changes and steroid receptor coactivator recruitment than natural estrogens.

García-Becerra R, Borja-Cacho E, Cooney AJ, Smith CL, Lemus AE, Pérez-Palacios G, Larrea F.

J Steroid Biochem Mol Biol. 2006 May;99(2-3):108-14. Epub 2006 Apr 17.

PMID:
16616843
50.

The varied roles of nuclear receptors during vertebrate embryonic development.

Chung AC, Cooney AJ.

Nucl Recept Signal. 2003;1:e007. Epub 2003 Jun 27.

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