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Enhanced Tropism of Species B1 Adenoviral-Based Vectors for Primary Human Airway Epithelial Cells.

Li N, Cooney AL, Zhang W, Ehrhardt A, Sinn PL.

Mol Ther Methods Clin Dev. 2019 Jul 12;14:228-236. doi: 10.1016/j.omtm.2019.07.001. eCollection 2019 Sep 13.


A Novel AAV-mediated Gene Delivery System Corrects CFTR Function in Pigs.

Cooney AL, Thornell IM, Singh BK, Shah VS, Stoltz DA, McCray PB Jr, Zabner J, Sinn PL.

Am J Respir Cell Mol Biol. 2019 Dec;61(6):747-754. doi: 10.1165/rcmb.2019-0006OC.


Older Women's Experiences of Aging and Health: An Interpretive Phenomenological Study.

Tuohy D, Cooney A.

Gerontol Geriatr Med. 2019 Mar 7;5:2333721419834308. doi: 10.1177/2333721419834308. eCollection 2019 Jan-Dec.


Telling a 'good or white lie': The views of people living with dementia and their carers.

Casey D, Lynch U, Murphy K, Cooney A, Gannon M, Houghton C, Hunter A, Jordan F, Smyth S, Felzman H, Meskell P.

Dementia (London). 2019 Feb 25:1471301219831525. doi: 10.1177/1471301219831525. [Epub ahead of print]


Cystic Fibrosis Gene Therapy: Looking Back, Looking Forward.

Cooney AL, McCray PB Jr, Sinn PL.

Genes (Basel). 2018 Nov 7;9(11). pii: E538. doi: 10.3390/genes9110538. Review.


Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus.

Cooney AL, Singh BK, Loza LM, Thornell IM, Hippee CE, Powers LS, Ostedgaard LS, Meyerholz DK, Wohlford-Lenane C, Stoltz DA, B McCray P Jr, Sinn PL.

Nucleic Acids Res. 2018 Oct 12;46(18):9591-9600. doi: 10.1093/nar/gky773.


Generation of integration-free induced pluripotent stem cells from a patient with spina bifida.

Wang H, Zhao S, Finnell RH, George T, Cooney AJ.

Stem Cell Res. 2018 Aug;31:27-30. doi: 10.1016/j.scr.2018.05.007. Epub 2018 May 17.


TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus.

Brouillette RB, Phillips EK, Patel R, Mahauad-Fernandez W, Moller-Tank S, Rogers KJ, Dillard JA, Cooney AL, Martinez-Sobrido L, Okeoma C, Maury W.

J Virol. 2018 Jul 31;92(16). pii: e00093-18. doi: 10.1128/JVI.00093-18. Print 2018 Aug 15.


A Feasibility Study Comparing Platelet-Rich Plasma Injection With Saline for the Treatment of Plantar Fasciitis Using a Prospective, Randomized Trial Design.

Johnson-Lynn S, Cooney A, Ferguson D, Bunn D, Gray W, Coorsh J, Kakwani R, Townshend D.

Foot Ankle Spec. 2019 Apr;12(2):153-158. doi: 10.1177/1938640018776065. Epub 2018 May 21.


p63 Silencing induces reprogramming of cardiac fibroblasts into cardiomyocyte-like cells.

Patel V, Singh VP, Pinnamaneni JP, Sanagasetti D, Olive J, Mathison M, Cooney A, Flores ER, Crystal RG, Yang J, Rosengart TK.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):556-565.e1. doi: 10.1016/j.jtcvs.2018.03.162. Epub 2018 Apr 13.


Reciprocity of Action of Increasing Oct4 and Repressing p53 in Transdifferentiation of Mouse Embryonic Fibroblasts into Cardiac Myocytes.

Wang H, Zhao S, Barton M, Rosengart T, Cooney AJ.

Cell Reprogram. 2018 Feb;20(1):27-37. doi: 10.1089/cell.2017.0031.


The impact of life story work on person-centred care for people with dementia living in long-stay care settings in Ireland.

Cooney A, O'Shea E.

Dementia (London). 2019 Oct-Nov;18(7-8):2731-2746. doi: 10.1177/1471301218756123. Epub 2018 Feb 7. No abstract available.


Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene.

Staber JM, Pollpeter MJ, Anderson CG, Burrascano M, Cooney AL, Sinn PL, Rutkowski DT, Raschke WC, McCray PB.

Gene Ther. 2017 Nov;24(11):742-748. doi: 10.1038/gt.2017.67. Epub 2017 Sep 14.


Novel GP64 envelope variants for improved delivery to human airway epithelial cells.

Sinn PL, Hwang BY, Li N, Ortiz JLS, Shirazi E, Parekh KR, Cooney AL, Schaffer DV, McCray PB Jr.

Gene Ther. 2017 Oct;24(10):674-679. doi: 10.1038/gt.2017.78. Epub 2017 Sep 7.


Vesicular Stomatitis Virus Pseudotyped with Ebola Virus Glycoprotein Serves as a Protective, Noninfectious Vaccine against Ebola Virus Challenge in Mice.

Lennemann NJ, Herbert AS, Brouillette R, Rhein B, Bakken RA, Perschbacher KJ, Cooney AL, Miller-Hunt CL, Ten Eyck P, Biggins J, Olinger G, Dye JM, Maury W.

J Virol. 2017 Aug 10;91(17). pii: e00479-17. doi: 10.1128/JVI.00479-17. Print 2017 Sep 1.


Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice.

Lan ZJ, Krause MS, Redding SD, Li X, Wu GZ, Zhou HX, Bohler HC, Ko C, Cooney AJ, Zhou J, Lei ZM.

Mol Cell Endocrinol. 2017 Mar 15;444:26-37. doi: 10.1016/j.mce.2017.01.043. Epub 2017 Jan 28.


Outcomes of Renal Transplantation in Patients With Bipolar Affective Disorder and Schizophrenia: A National Retrospective Cohort Study.

Butler MI, McCartan D, Cooney A, Kelly PO, Ahmed I, Little D, MacHale S, Conlon P.

Psychosomatics. 2017 Jan - Feb;58(1):69-76. doi: 10.1016/j.psym.2016.08.010. Epub 2016 Sep 20.


Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate.

Chen IC, Hernandez C, Xu X, Cooney A, Wang Y, McCarrey JR.

Stem Cells Dev. 2016 Nov 15;25(22):1698-1708. Epub 2016 Oct 12.


Nurses' knowledge of pain and its management in older people.

Furjanic M, Cooney A, McCarthy B.

Nurs Older People. 2016 Oct 28;28(9):32-37.


Nurses', midwives' and key stakeholders' experiences and perceptions on requirements to demonstrate the maintenance of professional competence.

Casey M, Cooney A, O' Connell R, Hegarty JM, Brady AM, O' Reilly P, Kennedy C, Heffernan E, Fealy G, McNamara M, O' Connor L.

J Adv Nurs. 2017 Mar;73(3):653-664. doi: 10.1111/jan.13171. Epub 2016 Oct 28.


Qualitative exploration of stakeholders' perspectives of involuntary admission under the Mental Health Act 2001 in Ireland.

Smyth S, Casey D, Cooney A, Higgins A, McGuinness D, Bainbridge E, Keys M, Georgieva I, Brosnan L, Beecher C, Hallahan B, McDonald C, Murphy K.

Int J Ment Health Nurs. 2017 Dec;26(6):554-569. doi: 10.1111/inm.12270. Epub 2016 Oct 27.


Lentiviral-mediated phenotypic correction of cystic fibrosis pigs.

Cooney AL, Abou Alaiwa MH, Shah VS, Bouzek DC, Stroik MR, Powers LS, Gansemer ND, Meyerholz DK, Welsh MJ, Stoltz DA, Sinn PL, McCray PB Jr.

JCI Insight. 2016 Sep 8;1(14). pii: 88730. doi: 10.1172/jci.insight.88730.


Mesp1 Marked Cardiac Progenitor Cells Repair Infarcted Mouse Hearts.

Liu Y, Chen L, Diaz AD, Benham A, Xu X, Wijaya CS, Fa'ak F, Luo W, Soibam B, Azares A, Yu W, Lyu Q, Stewart MD, Gunaratne P, Cooney A, McConnell BK, Schwartz RJ.

Sci Rep. 2016 Aug 19;6:31457. doi: 10.1038/srep31457.


miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification.

Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, Liu Y.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9551-6. doi: 10.1073/pnas.1608256113. Epub 2016 Aug 10.


GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells.

Lan ZJ, Hu Y, Zhang S, Li X, Zhou H, Ding J, Klinge CM, Radde BN, Cooney AJ, Zhang J, Lei Z.

Breast Cancer Res Treat. 2016 Jul;158(2):263-76. doi: 10.1007/s10549-016-3880-2. Epub 2016 Jun 29.


Generation of electrophysiologically functional cardiomyocytes from mouse induced pluripotent stem cells.

Wang H, Xi Y, Zheng Y, Wang X, Cooney AJ.

Stem Cell Res. 2016 Mar;16(2):522-30. doi: 10.1016/j.scr.2016.02.032. Epub 2016 Feb 23.


Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells.

Wang H, Wang X, Xu X, Kyba M, Cooney AJ.

J Biol Chem. 2016 Apr 15;291(16):8644-52. doi: 10.1074/jbc.M115.694208. Epub 2016 Jan 14.


Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.

Li S, Moore AK, Zhu J, Li X, Zhou H, Lin J, He Y, Xing F, Pan Y, Bohler HC, Ding J, Cooney AJ, Lan Z, Lei Z.

Biol Reprod. 2016 Feb;94(2):41. doi: 10.1095/biolreprod.115.136358. Epub 2016 Jan 13.


The Irish living kidney donor program - why potential donors do not proceed to live kidney donation?

Connaughton DM, Harmon G, Cooney A, Williams Y, O'Regan J, O'Neill D, Cunningham P, Counihan A, O'Kelly P, McHale S, Denton M, O'Seaghdha CM, Magee C, Conlon P, Little D, Keogan M, de Freitas DG.

Clin Transplant. 2016 Jan;30(1):17-25. doi: 10.1111/ctr.12641. Epub 2015 Nov 24.


Genome-Wide Identification of MESP1 Targets Demonstrates Primary Regulation Over Mesendoderm Gene Activity.

Soibam B, Benham A, Kim J, Weng KC, Yang L, Xu X, Robertson M, Azares A, Cooney AJ, Schwartz RJ, Liu Y.

Stem Cells. 2015 Nov;33(11):3254-65. doi: 10.1002/stem.2111. Epub 2015 Aug 18.


Corrigendum: Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming.

Hirsch CL, Akdemir ZC, Wang L, Jayakumaran G, Trcka D, Weiss A, Hernandez JJ, Pan Q, Han H, Xu X, Xia Z, Salinger AP, Wilson M, Vizeacoumar F, Datti A, Li W, Cooney AJ, Barton MC, Blencowe BJ, Wrana JL, Dent SY.

Genes Dev. 2015 Jun 15;29(12):1341. doi: 10.1101/gad.266601.115. No abstract available.


Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming.

Hirsch CL, Coban Akdemir Z, Wang L, Jayakumaran G, Trcka D, Weiss A, Hernandez JJ, Pan Q, Han H, Xu X, Xia Z, Salinger AP, Wilson M, Vizeacoumar F, Datti A, Li W, Cooney AJ, Barton MC, Blencowe BJ, Wrana JL, Dent SY.

Genes Dev. 2015 Apr 15;29(8):803-16. doi: 10.1101/gad.255109.114. Epub 2015 Apr 15. Erratum in: Genes Dev. 2015 Jun 15;29(12):1341.


Tunable narrow band difference frequency THz wave generation in DAST via dual seed PPLN OPG.

Dolasinski B, Powers PE, Haus JW, Cooney A.

Opt Express. 2015 Feb 9;23(3):3669-80. doi: 10.1364/OE.23.003669.


Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells.

Liu L, Liu L, Leung LH, Cooney AJ, Chen C, Rosengart TK, Ma Y, Yang J.

J Biol Chem. 2015 Apr 24;290(17):10599-609. doi: 10.1074/jbc.M114.634790. Epub 2015 Mar 3.


Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease.

Goldstein DS, Sullivan P, Cooney A, Jinsmaa Y, Kopin IJ, Sharabi Y.

J Neurochem. 2015 Apr;133(1):14-25. doi: 10.1111/jnc.13042. Epub 2015 Feb 25.


The serotonin aldehyde, 5-HIAL, oligomerizes alpha-synuclein.

Jinsmaa Y, Cooney A, Sullivan P, Sharabi Y, Goldstein DS.

Neurosci Lett. 2015 Mar 17;590:134-7. doi: 10.1016/j.neulet.2015.01.064. Epub 2015 Jan 28.


Sox2 is the faithful marker for pluripotency in pig: evidence from embryonic studies.

Liu S, Bou G, Sun R, Guo S, Xue B, Wei R, Cooney AJ, Liu Z.

Dev Dyn. 2015 Apr;244(4):619-27. doi: 10.1002/dvdy.24248. Epub 2015 Jan 24.


Hybrid nonviral/viral vector systems for improved piggyBac DNA transposon in vivo delivery.

Cooney AL, Singh BK, Sinn PL.

Mol Ther. 2015 Apr;23(4):667-74. doi: 10.1038/mt.2014.254. Epub 2015 Jan 5.


The accuracy of magnetic resonance imaging (MRI) in detecting meniscal pathology.

Chambers S, Cooney A, Caplan N, Dowen D, Kader D.

J R Nav Med Serv. 2014;100(2):157-60.


Germ cell nuclear factor regulates gametogenesis in developing gonads.

Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Araúzo-Bravo MJ, Gentile L, Greber B, Hübner K, Sebastiano V, Wu G, Schöler HR, Cooney AJ.

PLoS One. 2014 Aug 20;9(8):e103985. doi: 10.1371/journal.pone.0103985. eCollection 2014.


Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease.

Casida JE, Ford B, Jinsmaa Y, Sullivan P, Cooney A, Goldstein DS.

Chem Res Toxicol. 2014 Aug 18;27(8):1359-61. doi: 10.1021/tx5002223. Epub 2014 Jul 24.


'Seeing me through my memories': a grounded theory study on using reminiscence with people with dementia living in long-term care.

Cooney A, Hunter A, Murphy K, Casey D, Devane D, Smyth S, Dempsey L, Murphy E, Jordan F, O'Shea E.

J Clin Nurs. 2014 Dec;23(23-24):3564-74. doi: 10.1111/jocn.12645. Epub 2014 Jul 12.


Improving the quality of life for older people in long-term care settings.

Murphy K, Cooney A, Casey D.

J Comp Eff Res. 2014 May;3(3):301-15. doi: 10.2217/cer.14.20. Review.


Policy-makers' views on impact of specialist and advanced practitioner roles in Ireland: the SCAPE study.

Begley C, Murphy K, Higgins A, Cooney A.

J Nurs Manag. 2014 May;22(4):410-22. doi: 10.1111/jonm.12018. Epub 2012 Dec 1.


"Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors.

Mathison M, Singh VP, Gersch RP, Ramirez MO, Cooney A, Kaminsky SM, Chiuchiolo MJ, Nasser A, Yang J, Crystal RG, Rosengart TK.

J Thorac Cardiovasc Surg. 2014 Oct;148(4):1656-1664.e2. doi: 10.1016/j.jtcvs.2014.03.033. Epub 2014 Mar 27.


Divalent metal ions enhance DOPAL-induced oligomerization of alpha-synuclein.

Jinsmaa Y, Sullivan P, Gross D, Cooney A, Sharabi Y, Goldstein DS.

Neurosci Lett. 2014 May 21;569:27-32. doi: 10.1016/j.neulet.2014.03.016. Epub 2014 Mar 23.


The impact of reminiscence on the quality of life of residents with dementia in long-stay care.

O'Shea E, Devane D, Cooney A, Casey D, Jordan F, Hunter A, Murphy E, Newell J, Connolly S, Murphy K.

Int J Geriatr Psychiatry. 2014 Oct;29(10):1062-70. doi: 10.1002/gps.4099. Epub 2014 Mar 14.


Reminiscence in dementia: a concept analysis.

Dempsey L, Murphy K, Cooney A, Casey D, O'Shea E, Devane D, Jordan F, Hunter A.

Dementia (London). 2014 Mar 1;13(2):176-92. doi: 10.1177/1471301212456277. Epub 2012 Aug 17.


GCNF-dependent activation of cyclin D1 expression via repression of Mir302a during ESC differentiation.

Wang H, Wang X, Archer TK, Zwaka TP, Cooney AJ.

Stem Cells. 2014 Jun;32(6):1527-37. doi: 10.1002/stem.1689.


Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8.

Chakravarti D, Su X, Cho MS, Bui NH, Coarfa C, Venkatanarayan A, Benham AL, Flores González RE, Alana J, Xiao W, Leung ML, Vin H, Chan IL, Aquino A, Müller N, Wang H, Cooney AJ, Parker-Thornburg J, Tsai KY, Gunaratne PH, Flores ER.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):E572-81. doi: 10.1073/pnas.1319743111. Epub 2014 Jan 21.

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