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Items: 1 to 50 of 272

1.

Peroxidase-like activity of uncoupled cytochrome P450: studies with bilirubin and toxicological implications of uncoupling.

De Matteis F, Ballou DP, Coon MJ, Estabrook RW, Haines DC.

Biochem Pharmacol. 2012 Aug 1;84(3):374-82. doi: 10.1016/j.bcp.2012.04.016. Epub 2012 Apr 28.

PMID:
22564776
2.

Products from enzyme-catalyzed oxidations of norcarenes.

Newcomb M, Lansakara-P DS, Kim HY, Chandrasena RE, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ.

J Org Chem. 2007 Feb 16;72(4):1128-33.

3.

Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane.

Newcomb M, Chandrasena RE, Lansakara-P DS, Kim HY, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ.

J Org Chem. 2007 Feb 16;72(4):1121-7.

4.

Oxidative aldehyde deformylation catalyzed by NADPH-cytochrome P450 reductase and the flavoprotein domain of neuronal nitric oxide synthase.

Vatsis KP, Coon MJ.

Biochem Biophys Res Commun. 2005 Dec 2;337(4):1107-11. Epub 2005 Oct 5.

PMID:
16226717
5.

Omega oxygenases: nonheme-iron enzymes and P450 cytochromes.

Coon MJ.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):378-85. Epub 2005 Aug 30. Review.

PMID:
16165094
6.

Cytochrome P450: nature's most versatile biological catalyst.

Coon MJ.

Annu Rev Pharmacol Toxicol. 2005;45:1-25. Review.

PMID:
15832443
8.

Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes.

Chandrasena RE, Vatsis KP, Coon MJ, Hollenberg PF, Newcomb M.

J Am Chem Soc. 2004 Jan 14;126(1):115-26.

PMID:
14709076
9.

Multiple oxidants and multiple mechanisms in cytochrome P450 catalysis.

Coon MJ.

Biochem Biophys Res Commun. 2003 Dec 5;312(1):163-8. Review. No abstract available.

PMID:
14630036
10.

Irwin C. Gunsalus, versatile and creative scientist.

Coon MJ, Sligar SG.

Biochem Biophys Res Commun. 2003 Dec 5;312(1):1-6, 9-27. No abstract available.

PMID:
14630011
11.

Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations.

Newcomb M, Aebisher D, Shen R, Chandrasena RE, Hollenberg PF, Coon MJ.

J Am Chem Soc. 2003 May 21;125(20):6064-5.

PMID:
12785830
12.

Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.

Newcomb M, Hollenberg PF, Coon MJ.

Arch Biochem Biophys. 2003 Jan 1;409(1):72-9. Review.

PMID:
12464246
13.

Ronald W. Estabrook: gifted scientist with the same versatile, energetic, and colorful qualities as cytochrome P450.

Coon MJ.

Arch Biochem Biophys. 2003 Jan 1;409(1):16-7. No abstract available.

PMID:
12464239
14.
15.

Evaluation of norcarane as a probe for radicals in cytochome p450- and soluble methane monooxygenase-catalyzed hydroxylation reactions.

Newcomb M, Shen R, Lu Y, Coon MJ, Hollenberg PF, Kopp DA, Lippard SJ.

J Am Chem Soc. 2002 Jun 19;124(24):6879-86. Erratum in: J Am Chem Soc. 2006 Feb 1;128(4):1394.

PMID:
12059209
16.

Enzyme ingenuity in biological oxidations: a trail leading to cytochrome p450.

Coon MJ.

J Biol Chem. 2002 Aug 9;277(32):28351-63. Epub 2002 Jun 5. No abstract available.

18.

Stopped-flow spectrophotometric analysis of intermediates in the peroxo-dependent inactivation of cytochrome P450 by aldehydes.

Raner GM, Hatchell AJ, Morton PE, Ballou DP, Coon MJ.

J Inorg Biochem. 2000 Aug 31;81(3):153-60.

PMID:
11051560
19.
20.

EPR spectrometry of cytochrome P450 2B4: effects of mutations and substrate binding.

LeLean JE, Moon N, Dunham WR, Coon MJ.

Biochem Biophys Res Commun. 2000 Sep 24;276(2):762-6.

PMID:
11027544
21.

Discrete species of activated oxygen yield different cytochrome P450 heme adducts from aldehydes.

Kuo CL, Raner GM, Vaz AD, Coon MJ.

Biochemistry. 1999 Aug 10;38(32):10511-8.

PMID:
10441147
22.

Multiple activated oxygen species in P450 catalysis: contributions To specificity in drug metabolism.

Coon MJ, Vaz AD, McGinnity DF, Peng HM.

Drug Metab Dispos. 1998 Dec;26(12):1190-3. Review.

PMID:
9860926
23.

Membrane topology of cytochrome P450 2B4 in Langmuir-Blodgett monolayers.

Shank-Retzlaff ML, Raner GM, Coon MJ, Sligar SG.

Arch Biochem Biophys. 1998 Nov 1;359(1):82-8.

PMID:
9799564
24.
25.
26.

Characterization of the cytochrome P450 CYP2J4: expression in rat small intestine and role in retinoic acid biotransformation from retinal.

Zhang QY, Raner G, Ding X, Dunbar D, Coon MJ, Kaminsky LS.

Arch Biochem Biophys. 1998 May 15;353(2):257-64.

PMID:
9606960
27.
29.
30.

Evidence for a role of a perferryl-oxygen complex, FeO3+, in the N-oxygenation of amines by cytochrome P450 enzymes.

Guengerich FP, Vaz AD, Raner GN, Pernecky SJ, Coon MJ.

Mol Pharmacol. 1997 Jan;51(1):147-51.

PMID:
9016357
31.

Metabolic activation of 2,6-dichlorobenzonitrile, an olfactory-specific toxicant, by rat, rabbit, and human cytochromes P450.

Ding X, Spink DC, Bhama JK, Sheng JJ, Vaz AD, Coon MJ.

Mol Pharmacol. 1996 Jun;49(6):1113-21.

PMID:
8649351
33.

Cytochrome P450 2: peroxidative reactions of diversozymes.

Coon MJ, Vaz AD, Bestervelt LL.

FASEB J. 1996 Mar;10(4):428-34. Review.

PMID:
8647341
35.

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

Nelson DR, Koymans L, Kamataki T, Stegeman JJ, Feyereisen R, Waxman DJ, Waterman MR, Gotoh O, Coon MJ, Estabrook RW, Gunsalus IC, Nebert DW.

Pharmacogenetics. 1996 Feb;6(1):1-42. Review.

PMID:
8845856
36.

N-terminal modifications that alter P450 membrane targeting and function.

Pernecky SJ, Coon MJ.

Methods Enzymol. 1996;272:25-34. No abstract available.

PMID:
8791759
37.
39.
40.

Oxidative cleavage of esters and amides to carbonyl products by cytochrome P450.

Peng HM, Raner GM, Vaz AD, Coon MJ.

Arch Biochem Biophys. 1995 Apr 20;318(2):333-9.

PMID:
7733661
41.

William Cumming Rose - April 4, 1887-September 25, 1985.

Carter HE, Coon MJ.

Biogr Mem Natl Acad Sci. 1995;68:253-71. No abstract available.

PMID:
11616352
42.

Steroid metabolism by rabbit olfactory-specific P450 2G1.

Ding X, Coon MJ.

Arch Biochem Biophys. 1994 Dec;315(2):454-9.

43.
45.

The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase.

Voznesensky AI, Schenkman JB, Pernecky SJ, Coon MJ.

Biochem Biophys Res Commun. 1994 Aug 30;203(1):156-61.

46.
48.

Clinical pharmacokinetics and relative bioavailability of oral procaterol.

Eldon MA, Battle MM, Coon MJ, Nordblom GD, Sedman AJ, Colburn WA.

Pharm Res. 1993 Apr;10(4):603-5.

PMID:
8483846
50.

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.

Nelson DR, Kamataki T, Waxman DJ, Guengerich FP, Estabrook RW, Feyereisen R, Gonzalez FJ, Coon MJ, Gunsalus IC, Gotoh O, et al.

DNA Cell Biol. 1993 Jan-Feb;12(1):1-51. Review.

PMID:
7678494

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