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Items: 1 to 50 of 84

1.

Dose-dependent selection drives lineage replacement during the experimental evolution of SDHI fungicide resistance in Zymoseptoria tritici.

Gutiérrez-Alonso O, Hawkins NJ, Cools HJ, Shaw MW, Fraaije BA.

Evol Appl. 2017 Sep 3;10(10):1055-1066. doi: 10.1111/eva.12511. eCollection 2017 Dec.

2.

Effectiveness of post-exposition prophylaxis with oseltamivir in nursing homes: a randomised controlled trial over four seasons.

van der Sande MA, Meijer A, Sen-Kerpiclik F, Enserink R, Cools HJ, Overduin P, Ferreira JM, Veldman-Ariessen MJ.

Emerg Themes Epidemiol. 2014 Sep 10;11:13. doi: 10.1186/1742-7622-11-13. eCollection 2014.

3.
4.
5.

Response to David Nace and Paul Drinka.

Caljouw MA, van den Hout WB, Putter H, Achterberg WP, Cools HJ, Gussekloo J.

J Am Geriatr Soc. 2014 Aug;62(8):1617-8. doi: 10.1111/jgs.12949. No abstract available.

PMID:
25116999
6.

Molecular screening for avirulence alleles AvrLm1 and AvrLm6 in airborne inoculum of Leptosphaeria maculans and winter oilseed rape (Brassica napus) plants from Poland and the UK.

Kaczmarek J, Latunde-Dada AO, Irzykowski W, Cools HJ, Stonard JF, Brachaczek A, Jedryczka M.

J Appl Genet. 2014 Nov;55(4):529-39. doi: 10.1007/s13353-014-0235-8. Epub 2014 Aug 1.

7.

Natural course of care dependency in residents of long-term care facilities: prospective follow-up study.

Caljouw MA, Cools HJ, Gussekloo J.

BMC Geriatr. 2014 May 22;14:67. doi: 10.1186/1471-2318-14-67.

8.

Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance.

Hawkins NJ, Cools HJ, Sierotzki H, Shaw MW, Knogge W, Kelly SL, Kelly DE, Fraaije BA.

Mol Biol Evol. 2014 Jul;31(7):1793-802. doi: 10.1093/molbev/msu134. Epub 2014 Apr 14.

9.

The implementation of integrated emotion-oriented care: did it actually change the attitude, skills and time spent of trained caregivers?

van der Kooij CH, Dröes RM, de Lange J, Ettema TP, Cools HJ, van Tilburg W.

Dementia (London). 2013 Sep;12(5):536-50. doi: 10.1177/1471301211435187. Epub 2012 Mar 16.

PMID:
24337328
10.

Alterations in the predicted regulatory and coding regions of the sterol 14α-demethylase gene (CYP51) confer decreased azole sensitivity in the oilseed rape pathogen Pyrenopeziza brassicae.

Carter HE, Fraaije BA, West JS, Kelly SL, Mehl A, Shaw MW, Cools HJ.

Mol Plant Pathol. 2014 Jun;15(5):513-22. doi: 10.1111/mpp.12106. Epub 2014 Feb 8.

PMID:
24298976
11.

Detection and molecular characterisation of Pyrenopeziza brassicae isolates resistant to methyl benzimidazole carbamates.

Carter HE, Cools HJ, West JS, Shaw MW, Fraaije BA.

Pest Manag Sci. 2013 Sep;69(9):1040-8. doi: 10.1002/ps.3585. Epub 2013 Jul 9.

PMID:
23760810
12.

Clinically diagnosed infections predict disability in activities of daily living among the oldest-old in the general population: the Leiden 85-plus Study.

Caljouw MA, Kruijdenberg SJ, de Craen AJ, Cools HJ, den Elzen WP, Gussekloo J.

Age Ageing. 2013 Jul;42(4):482-8. doi: 10.1093/ageing/aft033. Epub 2013 Mar 12.

13.

Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function.

Fan J, Urban M, Parker JE, Brewer HC, Kelly SL, Hammond-Kosack KE, Fraaije BA, Liu X, Cools HJ.

New Phytol. 2013 May;198(3):821-35. doi: 10.1111/nph.12193. Epub 2013 Feb 27.

14.

Prothioconazole and prothioconazole-desthio activities against Candida albicans sterol 14-α-demethylase.

Parker JE, Warrilow AG, Cools HJ, Fraaije BA, Lucas JA, Rigdova K, Griffiths WJ, Kelly DE, Kelly SL.

Appl Environ Microbiol. 2013 Mar;79(5):1639-45. doi: 10.1128/AEM.03246-12. Epub 2012 Dec 28.

15.

Exploitation of genomics in fungicide research: current status and future perspectives.

Cools HJ, Hammond-Kosack KE.

Mol Plant Pathol. 2013 Feb;14(2):197-210. doi: 10.1111/mpp.12001. Epub 2012 Nov 16. Review.

PMID:
23157348
16.

Update on mechanisms of azole resistance in Mycosphaerella graminicola and implications for future control.

Cools HJ, Fraaije BA.

Pest Manag Sci. 2013 Feb;69(2):150-5. doi: 10.1002/ps.3348. Epub 2012 Jun 22. Review.

PMID:
22730104
17.

Overexpression of the sterol 14α-demethylase gene (MgCYP51) in Mycosphaerella graminicola isolates confers a novel azole fungicide sensitivity phenotype.

Cools HJ, Bayon C, Atkins S, Lucas JA, Fraaije BA.

Pest Manag Sci. 2012 Jul;68(7):1034-40. doi: 10.1002/ps.3263. Epub 2012 Mar 12.

PMID:
22411894
18.

[Long-term goals for oral health].

Bots CP, van Dalen A, Cools HJ.

Ned Tijdschr Tandheelkd. 2012 Jan;119(1):13-6. Dutch.

PMID:
22368835
19.

Risk assessment studies on succinate dehydrogenase inhibitors, the new weapons in the battle to control Septoria leaf blotch in wheat.

Fraaije BA, Bayon C, Atkins S, Cools HJ, Lucas JA, Fraaije MW.

Mol Plant Pathol. 2012 Apr;13(3):263-75. doi: 10.1111/j.1364-3703.2011.00746.x. Epub 2011 Sep 20.

PMID:
21933337
20.

Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.

Mullins JG, Parker JE, Cools HJ, Togawa RC, Lucas JA, Fraaije BA, Kelly DE, Kelly SL.

PLoS One. 2011;6(6):e20973. doi: 10.1371/journal.pone.0020973. Epub 2011 Jun 27.

21.

Finished genome of the fungal wheat pathogen Mycosphaerella graminicola reveals dispensome structure, chromosome plasticity, and stealth pathogenesis.

Goodwin SB, M'barek SB, Dhillon B, Wittenberg AH, Crane CF, Hane JK, Foster AJ, Van der Lee TA, Grimwood J, Aerts A, Antoniw J, Bailey A, Bluhm B, Bowler J, Bristow J, van der Burgt A, Canto-Canché B, Churchill AC, Conde-Ferràez L, Cools HJ, Coutinho PM, Csukai M, Dehal P, De Wit P, Donzelli B, van de Geest HC, van Ham RC, Hammond-Kosack KE, Henrissat B, Kilian A, Kobayashi AK, Koopmann E, Kourmpetis Y, Kuzniar A, Lindquist E, Lombard V, Maliepaard C, Martins N, Mehrabi R, Nap JP, Ponomarenko A, Rudd JJ, Salamov A, Schmutz J, Schouten HJ, Shapiro H, Stergiopoulos I, Torriani SF, Tu H, de Vries RP, Waalwijk C, Ware SB, Wiebenga A, Zwiers LH, Oliver RP, Grigoriev IV, Kema GH.

PLoS Genet. 2011 Jun;7(6):e1002070. doi: 10.1371/journal.pgen.1002070. Epub 2011 Jun 9.

22.

Predictive factors of urinary tract infections among the oldest old in the general population. A population-based prospective follow-up study.

Caljouw MA, den Elzen WP, Cools HJ, Gussekloo J.

BMC Med. 2011 May 16;9:57. doi: 10.1186/1741-7015-9-57.

23.

Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities.

den Elzen WP, Vossen AC, Cools HJ, Westendorp RG, Kroes AC, Gussekloo J.

Vaccine. 2011 Jun 24;29(29-30):4869-74. doi: 10.1016/j.vaccine.2011.03.086. Epub 2011 Apr 15.

PMID:
21497631
24.

Impact of recently emerged sterol 14{alpha}-demethylase (CYP51) variants of Mycosphaerella graminicola on azole fungicide sensitivity.

Cools HJ, Mullins JG, Fraaije BA, Parker JE, Kelly DE, Lucas JA, Kelly SL.

Appl Environ Microbiol. 2011 Jun;77(11):3830-7. doi: 10.1128/AEM.00027-11. Epub 2011 Apr 8.

25.

Mechanism of binding of prothioconazole to Mycosphaerella graminicola CYP51 differs from that of other azole antifungals.

Parker JE, Warrilow AG, Cools HJ, Martel CM, Nes WD, Fraaije BA, Lucas JA, Kelly DE, Kelly SL.

Appl Environ Microbiol. 2011 Feb;77(4):1460-5. doi: 10.1128/AEM.01332-10. Epub 2010 Dec 17.

26.

Vertegenwoordiging en verantwoordelijkheid : Over medische verantwoordelijkheid en mondige familieleden.

Touwen DP, Cools HJ, Engberts DP.

Tijdschr Gerontol Geriatr. 2010 Sep;2010(1):19-26. Dutch. No abstract available.

PMID:
23203305
27.

How much time should long-term care and geriatric rehabilitation facilities (nursing homes) spend on infection control?

van den Broek PJ, Cools HJ, Wulf M, Das PH.

Am J Infect Control. 2010 Nov;38(9):723-5. doi: 10.1016/j.ajic.2010.03.008.

PMID:
20605266
28.

[Proxy consent and responsibility: professional autonomy and adamant family members].

Touwen DP, Cools HJ, Engberts DP.

Tijdschr Gerontol Geriatr. 2010 Feb;41(1):19-26. Dutch.

PMID:
20333953
29.

Heterologous expression of mutated eburicol 14alpha-demethylase (CYP51) proteins of Mycosphaerella graminicola to assess effects on azole fungicide sensitivity and intrinsic protein function.

Cools HJ, Parker JE, Kelly DE, Lucas JA, Fraaije BA, Kelly SL.

Appl Environ Microbiol. 2010 May;76(9):2866-72. doi: 10.1128/AEM.02158-09. Epub 2010 Mar 19.

30.

Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides.

Bean TP, Cools HJ, Lucas JA, Hawkins ND, Ward JL, Shaw MW, Fraaije BA.

FEMS Microbiol Lett. 2009 Jun;296(2):266-73. doi: 10.1111/j.1574-6968.2009.01645.x. Epub 2009 May 8.

31.

Benefits of increasing the dose of influenza vaccine in residents of long-term care facilities: a randomized placebo-controlled trial.

Cools HJ, Gussekloo J, Remmerswaal JE, Remarque EJ, Kroes AC.

J Med Virol. 2009 May;81(5):908-14. doi: 10.1002/jmv.21456.

PMID:
19319953
32.

Role of Ascospores in Further Spread of QoI-Resistant Cytochrome b Alleles (G143A) in Field Populations of Mycosphaerella graminicola.

Fraaije BA, Cools HJ, Fountaine J, Lovell DJ, Motteram J, West JS, Lucas JA.

Phytopathology. 2005 Aug;95(8):933-41. doi: 10.1094/PHYTO-95-0933.

33.

Are azole fungicides losing ground against Septoria wheat disease? Resistance mechanisms in Mycosphaerella graminicola.

Cools HJ, Fraaije BA.

Pest Manag Sci. 2008 Jul;64(7):681-4. doi: 10.1002/ps.1568.

PMID:
18366065
34.

Transcriptome profiling of the response of Mycosphaerella graminicola isolates to an azole fungicide using cDNA microarrays.

Cools HJ, Fraaije BA, Bean TP, Antoniw J, Lucas JA.

Mol Plant Pathol. 2007 Sep;8(5):639-51. doi: 10.1111/j.1364-3703.2007.00411.x.

PMID:
20507527
35.

A novel substitution I381V in the sterol 14alpha-demethylase (CYP51) of Mycosphaerella graminicola is differentially selected by azole fungicides.

Fraaije BA, Cools HJ, Kim SH, Motteram J, Clark WS, Lucas JA.

Mol Plant Pathol. 2007 May;8(3):245-54. doi: 10.1111/j.1364-3703.2007.00388.x.

PMID:
20507496
36.

Impact of changes in the target P450 CYP51 enzyme associated with altered triazole-sensitivity in fungal pathogens of cereal crops.

Cools HJ, Fraaije BA, Kim SH, Lucas JA.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1219-22.

PMID:
17073789
37.

Use of oseltamivir in Dutch nursing homes during the 2004-2005 influenza season.

van der Sande MA, Ruijs WL, Meijer A, Cools HJ, van der Plas SM.

Vaccine. 2006 Nov 10;24(44-46):6664-9. Epub 2006 Jun 6.

PMID:
16797806
38.

[Death due to or despite the doctor].

Cools HJ.

Ned Tijdschr Geneeskd. 2006 Mar 18;150(11):594-6. Dutch.

PMID:
16610495
39.

[There is no natural death without suffering, even in a nursing home].

Cools HJ, van Balen R.

Ned Tijdschr Geneeskd. 2006 Feb 4;150(5):230-2. Dutch.

PMID:
16493985
40.

[Stroke services are increasingly effective].

Cools HJ.

Ned Tijdschr Geneeskd. 2005 Oct 15;149(42):2321-3. Dutch.

PMID:
16261709
41.

[Practice guideline 'Influenza prevention in nursing homes and care homes', issued by the Dutch Society of Nursing Home Specialists].

Cools HJ.

Ned Tijdschr Geneeskd. 2005 Jan 22;149(4):213. Dutch. No abstract available.

PMID:
15702743
42.

[Practice guideline 'Influenza prevention in nursing homes and care homes', issued by the Dutch Society of Nursing Home Specialists; division of tasks between nursing home specialist, general practitioner and company doctor].

Cools HJ, van Essen GA; Dutch Society of Nursing Home Specialists.

Ned Tijdschr Geneeskd. 2005 Jan 15;149(3):119-24; discussion 116-8. Review. Dutch.

PMID:
15693586
43.

[Replacement of the femoral head due to fracture of the hip: prognostic factors for the duration of hospitalisation or institutionalisation and mortality].

van Balen R, Cools HJ.

Ned Tijdschr Geneeskd. 2004 Mar 20;148(12):599-600; author reply 600. Dutch. No abstract available.

PMID:
15074186
44.

Classifying the probability of urinary incontinence in psychogeriatric nursing home patients.

Valk M, Moons KG, Cools HJ, Schrijvers AJ.

Arch Gerontol Geriatr. 2002 Feb;34(1):79-91.

PMID:
14764312
45.

The relationship between difficulties in feeding oneself and loss of weight in nursing-home patients with dementia.

Berkhout AM, Cools HJ, van Houwelingen HC.

Age Ageing. 1998 Sep;27(5):637-41.

PMID:
12675103
46.

A cost-minimisation study of alternative discharge policies after hip fracture repair.

Polder JJ, van Balen R, Steyerberg EW, Cools HJ, Habbema JD.

Health Econ. 2003 Feb;12(2):87-100.

PMID:
12563657
47.

Early discharge of hip fracture patients from hospital: transfer of costs from hospital to nursing home.

van Balen R, Steyerberg EW, Cools HJ, Polder JJ, Habbema JD.

Acta Orthop Scand. 2002 Oct;73(5):491-5.

PMID:
12440489
48.

[The dentist in the circle of care of dependent elderly].

Cools HJ.

Ned Tijdschr Tandheelkd. 1998 Oct;105(10):357-9. Dutch.

PMID:
11928448
49.

Hip fracture in elderly patients: outcomes for function, quality of life, and type of residence.

van Balen R, Steyerberg EW, Polder JJ, Ribbers TL, Habbema JD, Cools HJ.

Clin Orthop Relat Res. 2001 Sep;(390):232-43.

PMID:
11550871
50.

Measuring disability in nursing home residents: validity and reliability of a newly developed instrument.

Valk M, Post MW, Cools HJ, Schrijvers GA.

J Gerontol B Psychol Sci Soc Sci. 2001 May;56(3):P187-91.

PMID:
11316837

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