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Items: 1 to 50 of 495

1.

Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC.

Rovini A, Gurnev PA, Beilina A, Queralt-Martín M, Rosencrans W, Cookson MR, Bezrukov SM, Rostovtseva TK.

Cell Mol Life Sci. 2019 Nov 23. doi: 10.1007/s00018-019-03386-w. [Epub ahead of print]

PMID:
31760463
2.

Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia.

Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, Leonard HL, Grenn FP, Ruskey JA, Sabir M, Ahmed S, Makarious MB, Pihlstrøm L, Toft M, van Hilten JJ, Marinus J, Schulte C, Brockmann K, Sharma M, Siitonen A, Majamaa K, Eerola-Rautio J, Tienari PJ, Team TAR, Pantelyat A, Hillis AE, Dawson TM, Rosenthal LS, Albert MS, Resnick SM, Ferrucci L, Morris CM, Pletnikova O, Troncoso J, Grosset D, Lesage S, Corvol JC, Brice A, Noyce AJ, Masliah E, Wood N, Hardy J, Shulman LM, Jankovic J, Shulman JM, Heutink P, Gasser T, Cannon P, Scholz SW, Morris H, Cookson MR, Nalls MA, Gan-Or Z, Singleton AB.

Brain. 2019 Nov 22. pii: awz350. doi: 10.1093/brain/awz350. [Epub ahead of print]

PMID:
31755958
3.

The prognostic value of the neutrophil-to-lymphocyte ratio in patients with muscle-invasive bladder cancer treated with neoadjuvant chemotherapy and radical cystectomy.

Black AJ, Zargar H, Zargar-Shoshtari K, Fairey AS, Mertens LS, Dinney CP, Mir MC, Krabbe LM, Cookson MS, Jacobsen NE, Griffin J, Montgomery JS, Vasdev N, Yu EY, Xylinas E, Campain NJ, Kassouf W, Dall'Era MA, Seah JA, Ercole CE, Horenblas S, McGrath JS, Aning J, Shariat SF, Wright JL, Thorpe AC, Morgan TM, Holzbeierlein JM, Bivalacqua TJ, North S, Barocas DA, Lotan Y, Grivas P, Stephenson AJ, Shah JB, van Rhijn BW, Spiess PE, Daneshmand S, Sridhar SS, Black PC.

Urol Oncol. 2020 Jan;38(1):3.e17-3.e27. doi: 10.1016/j.urolonc.2019.09.023. Epub 2019 Oct 31.

PMID:
31676278
4.
5.

Proteomics: techniques and applications in neuroscience.

Cookson MR.

J Neurochem. 2019 Nov;151(4):394-396. doi: 10.1111/jnc.14867. Epub 2019 Oct 17.

PMID:
31625157
6.

Predictors of Recurrence, and Progression-Free and Overall Survival following Open versus Robotic Radical Cystectomy: Analysis from the RAZOR Trial with a 3-Year Followup.

Venkatramani V, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND, Shabsigh A, Barocas DA, Quek ML, Dash A, Kibel AS, Pruthi RS, Montgomery JS, Weight CJ, Sharp DS, Chang SS, Cookson MS, Gupta GN, Gorbonos A, Uchio EM, Skinner E, Soodana-Prakash N, Becerra MF, Swain S, Kendrick K, Smith JA Jr, Thompson IM, Parekh DJ.

J Urol. 2019 Sep 24:101097JU0000000000000565. doi: 10.1097/JU.0000000000000565. [Epub ahead of print]

PMID:
31549935
7.

Reply by Authors.

Ritch CR, Cookson MS, Clark PE, Chang SS, Fakhoury K, Ralls V, Thu MH, Penson DF, Smith JA Jr, Silver HJ.

J Urol. 2019 Oct;202(4):820. doi: 10.1097/JU.0000000000000375. Epub 2019 Sep 6. No abstract available.

PMID:
31166841
8.

DNAJC proteins and pathways to parkinsonism.

Roosen DA, Blauwendraat C, Cookson MR, Lewis PA.

FEBS J. 2019 Aug;286(16):3080-3094. doi: 10.1111/febs.14936. Epub 2019 Jun 20. Review.

PMID:
31120186
9.

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.

Russo I, Kaganovich A, Ding J, Landeck N, Mamais A, Varanita T, Biosa A, Tessari I, Bubacco L, Greggio E, Cookson MR.

Neurobiol Dis. 2019 Sep;129:67-78. doi: 10.1016/j.nbd.2019.05.012. Epub 2019 May 15.

PMID:
31102768
10.

Optimal Trial Design for Studying Urinary Markers in Bladder Cancer: A Collaborative Review.

Lotan Y, Black PC, Caba L, Chang SS, Cookson MS, Daneshmand S, Kamat AM, McKiernan JM, Pruthi RS, Ritch CR, Steinberg GD, Svatek RS, Zwarthoff EC.

Eur Urol Oncol. 2018 Aug;1(3):223-230. doi: 10.1016/j.euo.2018.04.010. Epub 2018 May 15. Review.

PMID:
31102625
11.

The role of Rab GTPases in the pathobiology of Parkinson' disease.

Bonet-Ponce L, Cookson MR.

Curr Opin Cell Biol. 2019 Aug;59:73-80. doi: 10.1016/j.ceb.2019.03.009. Epub 2019 May 1. Review.

PMID:
31054512
12.

Proteomics; applications in familial Parkinson's disease.

Li Y, Cookson MR.

J Neurochem. 2019 Nov;151(4):446-458. doi: 10.1111/jnc.14708. Epub 2019 Jul 9. Review.

PMID:
31022302
13.

Glial phagocytic clearance in Parkinson's disease.

Tremblay ME, Cookson MR, Civiero L.

Mol Neurodegener. 2019 Apr 5;14(1):16. doi: 10.1186/s13024-019-0314-8. Review.

14.

LRRK2 links genetic and sporadic Parkinson's disease.

Kluss JH, Mamais A, Cookson MR.

Biochem Soc Trans. 2019 Apr 30;47(2):651-661. doi: 10.1042/BST20180462. Epub 2019 Mar 5. Review.

PMID:
30837320
15.

Assessment of APOE in atypical parkinsonism syndromes.

Sabir MS, Blauwendraat C, Ahmed S, Serrano GE, Beach TG, Perkins M, Rice AC, Masliah E, Morris CM, Pihlstrom L, Pantelyat A, Resnick SM, Cookson MR, Hernandez DG, Albert M, Dawson TM, Rosenthal LS, Houlden H, Pletnikova O, Troncoso J, Scholz SW.

Neurobiol Dis. 2019 Jul;127:142-146. doi: 10.1016/j.nbd.2019.02.016. Epub 2019 Feb 21.

PMID:
30798004
16.

Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.

Wu CX, Liao J, Park Y, Reed X, Engel VA, Hoang NC, Takagi Y, Johnson SM, Wang M, Federici M, Nichols RJ, Sanishvili R, Cookson MR, Hoang QQ.

J Biol Chem. 2019 Apr 12;294(15):5907-5913. doi: 10.1074/jbc.RA119.007631. Epub 2019 Feb 22.

PMID:
30796162
17.

The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease.

Bandres-Ciga S, Saez-Atienzar S, Bonet-Ponce L, Billingsley K, Vitale D, Blauwendraat C, Gibbs JR, Pihlstrøm L, Gan-Or Z; International Parkinson's Disease Genomics Consortium (IPDGC), Cookson MR, Nalls MA, Singleton AB.

Mov Disord. 2019 Apr;34(4):460-468. doi: 10.1002/mds.27614. Epub 2019 Jan 24.

PMID:
30675927
18.

Genetic analysis of neurodegenerative diseases in a pathology cohort.

Blauwendraat C, Pletnikova O, Geiger JT, Murphy NA, Abramzon Y, Rudow G, Mamais A, Sabir MS, Crain B, Ahmed S, Rosenthal LS, Bakker CC, Faghri F, Chia R, Ding J, Dawson TM, Pantelyat A, Albert MS, Nalls MA, Resnick SM, Ferrucci L, Cookson MR, Hillis AE, Troncoso JC, Scholz SW.

Neurobiol Aging. 2019 Apr;76:214.e1-214.e9. doi: 10.1016/j.neurobiolaging.2018.11.007. Epub 2018 Nov 17.

PMID:
30528841
19.

The role of monogenic genes in idiopathic Parkinson's disease.

Reed X, Bandrés-Ciga S, Blauwendraat C, Cookson MR.

Neurobiol Dis. 2019 Apr;124:230-239. doi: 10.1016/j.nbd.2018.11.012. Epub 2018 Nov 15. Review.

PMID:
30448284
20.

Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4.

Russo I, Di Benedetto G, Kaganovich A, Ding J, Mercatelli D, Morari M, Cookson MR, Bubacco L, Greggio E.

J Neuroinflammation. 2018 Oct 27;15(1):297. doi: 10.1186/s12974-018-1337-8.

21.

Risk of Ovarian Malignancy in Patients Undergoing Radical Cystectomy for Bladder Cancer.

Abboud MA, Topham AK, Parker DC, Burks HR, Cookson MS, Patel SG.

Urology. 2019 Jan;123:181-185. doi: 10.1016/j.urology.2018.10.017. Epub 2018 Oct 22.

PMID:
30359713
22.

Perioperative Oral Nutrition Supplementation Reduces Prevalence of Sarcopenia following Radical Cystectomy: Results of a Prospective Randomized Controlled Trial.

Ritch CR, Cookson MS, Clark PE, Chang SS, Fakhoury K, Ralls V, Thu MH, Penson DF, Smith JA Jr, Silver HJ.

J Urol. 2019 Mar;201(3):470-477. doi: 10.1016/j.juro.2018.10.010.

PMID:
30359680
23.

Recent trends in the management of advanced prostate cancer.

Ritch C, Cookson M.

F1000Res. 2018 Sep 21;7. pii: F1000 Faculty Rev-1513. doi: 10.12688/f1000research.15382.1. eCollection 2018. Review.

24.

Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2.

Langston RG, Rudenko IN, Kumaran R, Hauser DN, Kaganovich A, Ponce LB, Mamais A, Ndukwe K, Dillman AA, Al-Saif AM, Beilina A, Cookson MR.

Neurochem Res. 2019 Jun;44(6):1446-1459. doi: 10.1007/s11064-018-2650-4. Epub 2018 Oct 5.

PMID:
30291536
25.

Converging pathways in neurodegeneration, from genetics to mechanisms.

Gan L, Cookson MR, Petrucelli L, La Spada AR.

Nat Neurosci. 2018 Oct;21(10):1300-1309. doi: 10.1038/s41593-018-0237-7. Epub 2018 Sep 26. Review.

26.

A comprehensive analysis of SNCA-related genetic risk in sporadic parkinson disease.

Pihlstrøm L, Blauwendraat C, Cappelletti C, Berge-Seidl V, Langmyhr M, Henriksen SP, van de Berg WDJ, Gibbs JR, Cookson MR; International Parkinson Disease Genomics Consortium; North American Brain Expression Consortium, Singleton AB, Nalls MA, Toft M.

Ann Neurol. 2018 Jul;84(1):117-129. doi: 10.1002/ana.25274. Epub 2018 Aug 26.

27.

Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts.

Parrado-Fernández C, Schneider B, Ankarcrona M, Conti MM, Cookson MR, Kivipelto M, Cedazo-Mínguez Á, Sandebring-Matton A.

J Cell Mol Med. 2018 Nov;22(11):5439-5449. doi: 10.1111/jcmm.13815. Epub 2018 Aug 22. Erratum in: J Cell Mol Med. 2019 Jun;23(6):4489.

28.

Finding useful biomarkers for Parkinson's disease.

Chen-Plotkin AS, Albin R, Alcalay R, Babcock D, Bajaj V, Bowman D, Buko A, Cedarbaum J, Chelsky D, Cookson MR, Dawson TM, Dewey R, Foroud T, Frasier M, German D, Gwinn K, Huang X, Kopil C, Kremer T, Lasch S, Marek K, Marto JA, Merchant K, Mollenhauer B, Naito A, Potashkin J, Reimer A, Rosenthal LS, Saunders-Pullman R, Scherzer CR, Sherer T, Singleton A, Sutherland M, Thiele I, van der Brug M, Van Keuren-Jensen K, Vaillancourt D, Walt D, West A, Zhang J.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaam6003. doi: 10.1126/scitranslmed.aam6003. Review.

29.

Epidemiology, prevention, screening, diagnosis, and evaluation: update of the ICUD-SIU joint consultation on bladder cancer.

Fernández MI, Brausi M, Clark PE, Cookson MS, Grossman HB, Khochikar M, Kiemeney LA, Malavaud B, Sanchez-Salas R, Soloway MS, Svatek RS, Vikram R, Vrieling A, Kamat AM.

World J Urol. 2019 Jan;37(1):3-13. doi: 10.1007/s00345-018-2436-y. Epub 2018 Aug 13. Review.

PMID:
30105454
30.

Castration-Resistant Prostate Cancer: AUA Guideline Amendment 2018.

Lowrance WT, Murad MH, Oh WK, Jarrard DF, Resnick MJ, Cookson MS.

J Urol. 2018 Dec;200(6):1264-1272. doi: 10.1016/j.juro.2018.07.090. Epub 2018 Aug 4.

PMID:
30086276
31.

Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology.

Mamais A, Manzoni C, Nazish I, Arber C, Sonustun B, Wray S, Warner TT, Cookson MR, Lewis PA, Bandopadhyay R.

Brain Res. 2018 Dec 15;1701:75-84. doi: 10.1016/j.brainres.2018.07.023. Epub 2018 Jul 25.

32.

Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease.

Blauwendraat C, Reed X, Kia DA, Gan-Or Z, Lesage S, Pihlstrøm L, Guerreiro R, Gibbs JR, Sabir M, Ahmed S, Ding J, Alcalay RN, Hassin-Baer S, Pittman AM, Brooks J, Edsall C, Hernandez DG, Chung SJ, Goldwurm S, Toft M, Schulte C, Bras J, Wood NW, Brice A, Morris HR, Scholz SW, Nalls MA, Singleton AB, Cookson MR; COURAGE-PD (Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson’s Disease) Consortium, the French Parkinson’s Disease Consortium, and the International Parkinson’s Disease Genomics Consortium (IPDGC).

JAMA Neurol. 2018 Nov 1;75(11):1416-1422. doi: 10.1001/jamaneurol.2018.1885.

33.

Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial.

Parekh DJ, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND, Shabsigh A, Barocas DA, Quek ML, Dash A, Kibel AS, Shemanski L, Pruthi RS, Montgomery JS, Weight CJ, Sharp DS, Chang SS, Cookson MS, Gupta GN, Gorbonos A, Uchio EM, Skinner E, Venkatramani V, Soodana-Prakash N, Kendrick K, Smith JA Jr, Thompson IM.

Lancet. 2018 Jun 23;391(10139):2525-2536. doi: 10.1016/S0140-6736(18)30996-6.

PMID:
29976469
34.

Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice.

Pellegrini L, Hauser DN, Li Y, Mamais A, Beilina A, Kumaran R, Wetzel A, Nixon-Abell J, Heaton G, Rudenko I, Alkaslasi M, Ivanina N, Melrose HL, Cookson MR, Harvey K.

Hum Mol Genet. 2018 Sep 15;27(18):3257-3271. doi: 10.1093/hmg/ddy232.

35.

AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons.

Soutar MPM, Kempthorne L, Miyakawa S, Annuario E, Melandri D, Harley J, O'Sullivan GA, Wray S, Hancock DC, Cookson MR, Downward J, Carlton M, Plun-Favreau H.

Sci Rep. 2018 Jun 11;8(1):8855. doi: 10.1038/s41598-018-26949-6.

36.

Concomitant CIS on TURBT does not impact oncological outcomes in patients treated with neoadjuvant or induction chemotherapy followed by radical cystectomy.

Vasdev N, Zargar H, Noël JP, Veeratterapillay R, Fairey AS, Mertens LS, Dinney CP, Mir MC, Krabbe LM, Cookson MS, Jacobsen NE, Gandhi NM, Griffin J, Montgomery JS, Yu EY, Xylinas E, Campain NJ, Kassouf W, Dall'Era MA, Seah JA, Ercole CE, Horenblas S, Sridhar SS, McGrath JS, Aning J, Shariat SF, Wright JL, Morgan TM, Bivalacqua TJ, North S, Barocas DA, Lotan Y, Grivas P, Stephenson AJ, Shah JB, van Rhijn BW, Daneshmand S, Spiess PE, Holzbeierlein JM, Thorpe A, Black PC.

World J Urol. 2019 Jan;37(1):165-172. doi: 10.1007/s00345-018-2361-0. Epub 2018 Jun 7.

PMID:
29882105
37.

Editorial Comment.

Patel S, Cookson MS.

J Urol. 2018 Aug;200(2):290-291. doi: 10.1016/j.juro.2018.03.152. Epub 2018 Jun 20. No abstract available.

PMID:
29777651
38.

Antenatal Vitamin D Preserves Placental Vascular and Fetal Growth in Experimental Chorioamnionitis Due to Intra-amniotic Endotoxin Exposure.

Cookson MW, Ryan SL, Seedorf GJ, Dodson RB, Abman SH, Mandell EW.

Am J Perinatol. 2018 Nov;35(13):1260-1270. doi: 10.1055/s-0038-1642033. Epub 2018 May 1.

PMID:
29715698
39.

Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activity.

Kluss JH, Conti MM, Kaganovich A, Beilina A, Melrose HL, Cookson MR, Mamais A.

NPJ Parkinsons Dis. 2018 Apr 19;4:13. doi: 10.1038/s41531-018-0049-1. eCollection 2018.

40.

Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies.

Erskine D, Ding J, Thomas AJ, Kaganovich A, Khundakar AA, Hanson PS, Taylor JP, McKeith IG, Attems J, Cookson MR, Morris CM.

Mov Disord. 2018 Jul;33(6):982-991. doi: 10.1002/mds.27333. Epub 2018 Mar 23.

41.

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.

Tomkins JE, Dihanich S, Beilina A, Ferrari R, Ilacqua N, Cookson MR, Lewis PA, Manzoni C.

Proteomics. 2018 May;18(10):e1700444. doi: 10.1002/pmic.201700444. Epub 2018 Apr 17.

42.

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation.

Madero-Pérez J, Fdez E, Fernández B, Lara Ordóñez AJ, Blanca Ramírez M, Gómez-Suaga P, Waschbüsch D, Lobbestael E, Baekelandt V, Nairn AC, Ruiz-Martínez J, Aiastui A, López de Munain A, Lis P, Comptdaer T, Taymans JM, Chartier-Harlin MC, Beilina A, Gonnelli A, Cookson MR, Greggio E, Hilfiker S.

Mol Neurodegener. 2018 Jan 23;13(1):3. doi: 10.1186/s13024-018-0235-y.

43.

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

Civiero L, Cogo S, Kiekens A, Morganti C, Tessari I, Lobbestael E, Baekelandt V, Taymans JM, Chartier-Harlin MC, Franchin C, Arrigoni G, Lewis PA, Piccoli G, Bubacco L, Cookson MR, Pinton P, Greggio E.

Front Mol Neurosci. 2017 Dec 14;10:417. doi: 10.3389/fnmol.2017.00417. eCollection 2017.

44.

The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo.

Nuriel T, Peng KY, Ashok A, Dillman AA, Figueroa HY, Apuzzo J, Ambat J, Levy E, Cookson MR, Mathews PM, Duff KE.

Front Neurosci. 2017 Dec 12;11:702. doi: 10.3389/fnins.2017.00702. eCollection 2017.

45.

The LRRK2 signalling system.

Price A, Manzoni C, Cookson MR, Lewis PA.

Cell Tissue Res. 2018 Jul;373(1):39-50. doi: 10.1007/s00441-017-2759-9. Epub 2018 Jan 8. Review.

46.

Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging.

Dillman AA, Majounie E, Ding J, Gibbs JR, Hernandez D, Arepalli S, Traynor BJ, Singleton AB, Galter D, Cookson MR.

Sci Rep. 2017 Dec 4;7(1):16890. doi: 10.1038/s41598-017-17322-0.

47.

LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.

Liu Z, Bryant N, Kumaran R, Beilina A, Abeliovich A, Cookson MR, West AB.

Hum Mol Genet. 2018 Jan 15;27(2):385-395. doi: 10.1093/hmg/ddx410.

48.

Urinary Diversion: Nutritional Evolution and Surgical Revolution.

Cookson MS.

Urol Clin North Am. 2018 Feb;45(1):xvii. doi: 10.1016/j.ucl.2017.10.001. No abstract available.

PMID:
29169456
49.

Robotic Cystectomy with Intracorporeal Urinary Diversion: Review of Current Techniques and Outcomes.

Thress TM, Cookson MS, Patel S.

Urol Clin North Am. 2018 Feb;45(1):67-77. doi: 10.1016/j.ucl.2017.09.009. Review.

PMID:
29169452
50.

Transition from androgenic to neurosteroidal action of 5α-androstane-3α, 17β-diol through the type A γ-aminobutyric acid receptor in prostate cancer progression.

Xia D, Lai DV, Wu W, Webb ZD, Yang Q, Zhao L, Yu Z, Thorpe JE, Disch BC, Ihnat MA, Jayaraman M, Dhanasekaran DN, Stratton KL, Cookson MS, Fung KM, Lin HK.

J Steroid Biochem Mol Biol. 2018 Apr;178:89-98. doi: 10.1016/j.jsbmb.2017.11.006. Epub 2017 Nov 21.

PMID:
29155210

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