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Items: 1 to 50 of 467

1.

Mass Spectrometry-Based Tissue Imaging: The Next Frontier in Clinical Diagnostics?

Leung F, Eberlin LS, Schwamborn K, Heeren RMA, Winograd N, Cooks RG.

Clin Chem. 2019 Feb 8. pii: clinchem.2018.289694. doi: 10.1373/clinchem.2018.289694. [Epub ahead of print] No abstract available.

PMID:
30737204
2.

Rapid determination of isocitrate dehydrogenase mutation status of human gliomas by extraction nanoelectrospray using a miniature mass spectrometer.

Pu F, Alfaro CM, Pirro V, Xie Z, Ouyang Z, Cooks RG.

Anal Bioanal Chem. 2019 Feb 2. doi: 10.1007/s00216-019-01632-5. [Epub ahead of print]

PMID:
30710208
3.

Intraoperative assessment of isocitrate dehydrogenase mutation status in human gliomas using desorption electrospray ionization-mass spectrometry.

Alfaro CM, Pirro V, Keating MF, Hattab EM, Cooks RG, Cohen-Gadol AA.

J Neurosurg. 2019 Jan 4:1-8. doi: 10.3171/2018.8.JNS181207. [Epub ahead of print]

PMID:
30611146
4.

High yield accelerated reactions in nonvolatile microthin films: chemical derivatization for analysis of single-cell intracellular fluid.

Wei Z, Zhang X, Wang J, Zhang S, Zhang X, Cooks RG.

Chem Sci. 2018 Aug 21;9(40):7779-7786. doi: 10.1039/c8sc03382j. eCollection 2018 Oct 28.

5.

Nebulization Prior to Isolation, Ionization, and Dissociation of the Neutral Serine Octamer Allows Its Characterization.

Zhang H, Wei Z, Jiang J, Cooks RG.

Angew Chem Int Ed Engl. 2018 Dec 21;57(52):17141-17145. doi: 10.1002/anie.201811098. Epub 2018 Nov 30.

PMID:
30371969
6.

Comprehensive lipid profiling of early stage oocytes and embryos by MRM profiling.

de Lima CB, Ferreira CR, Milazzotto MP, Sobreira TJP, Vireque AA, Cooks RG.

J Mass Spectrom. 2018 Dec;53(12):1247-1252. doi: 10.1002/jms.4301. No abstract available.

PMID:
30325087
7.

Logical MS/MS scans: a new set of operations for tandem mass spectrometry.

Snyder DT, Szalwinski LJ, Wells JM, Cooks RG.

Analyst. 2018 Nov 5;143(22):5438-5452. doi: 10.1039/c8an01661e.

PMID:
30311922
8.

Ion Mobility-Mass Spectrometry Using a Dual-Gated 3D Printed Ion Mobility Spectrometer.

Hollerbach A, Fedick PW, Cooks RG.

Anal Chem. 2018 Nov 20;90(22):13265-13272. doi: 10.1021/acs.analchem.8b02209. Epub 2018 Oct 29.

PMID:
30281279
9.

Multiple reaction monitoring (MRM)-profiling with biomarker identification by LC-QTOF to characterize coronary artery disease.

Yannell KE, Ferreira CR, Tichy SE, Cooks RG.

Analyst. 2018 Oct 8;143(20):5014-5022. doi: 10.1039/c8an01017j.

PMID:
30226503
10.

Fatty Acid Patterns Detected By Ambient Ionization Mass Spectrometry in Canine Invasive Urothelial Carcinoma From Dogs of Different Breeds.

D'Hue CA, Dhawan D, Peat T, Ramos-Vara J, Jarmusch A, Knapp DW, Cooks RG.

Bladder Cancer. 2018 Jul 30;4(3):283-291. doi: 10.3233/BLC-170125.

11.

Accelerated reactions in field desorption mass spectrometry.

Chen X, Cooks RG.

J Mass Spectrom. 2018 Oct;53(10):942-946. doi: 10.1002/jms.4254. Epub 2018 Aug 16.

PMID:
29935122
12.

Mass Spectrometry for Synthesis and Analysis.

Cooks RG, Yan X.

Annu Rev Anal Chem (Palo Alto Calif). 2018 Jun 12;11(1):1-28. doi: 10.1146/annurev-anchem-061417-125820.

PMID:
29894228
13.

High throughput reaction screening using desorption electrospray ionization mass spectrometry.

Wleklinski M, Loren BP, Ferreira CR, Jaman Z, Avramova L, Sobreira TJP, Thompson DH, Cooks RG.

Chem Sci. 2018 Jan 4;9(6):1647-1653. doi: 10.1039/c7sc04606e. eCollection 2018 Feb 14.

14.

Direct ion generation from swabs.

Jarmusch AK, Pirro V, Logsdon DL, Cooks RG.

Talanta. 2018 Jul 1;184:356-363. doi: 10.1016/j.talanta.2018.02.105. Epub 2018 Mar 12.

PMID:
29674054
15.

Accelerated Forced Degradation of Pharmaceuticals in Levitated Microdroplet Reactors.

Li Y, Liu Y, Gao H, Helmy R, Wuelfing WP, Welch CJ, Cooks RG.

Chemistry. 2018 May 23;24(29):7349-7353. doi: 10.1002/chem.201801176. Epub 2018 Apr 30.

PMID:
29653016
16.

Gas Phase Ion Chemistry to Determine Isoaspartate in a Peptide Backbone.

Ayrton ST, Chen X, Bain RM, Pulliam CJ, Achmatowicz M, Flick TG, Ren D, Cooks RG.

J Am Soc Mass Spectrom. 2018 Jul;29(7):1339-1344. doi: 10.1007/s13361-018-1923-0. Epub 2018 Mar 15.

PMID:
29546595
17.

Implementation of Precursor and Neutral Loss Scans on a Miniature Ion Trap Mass Spectrometer and Performance Comparison to a Benchtop Linear Ion Trap.

Snyder DT, Szalwinski LJ, Hilger R, Cooks RG.

J Am Soc Mass Spectrom. 2018 Jul;29(7):1355-1364. doi: 10.1007/s13361-018-1922-1. Epub 2018 Mar 13.

PMID:
29536414
18.

Precursor and Neutral Loss Scans in an RF Scanning Linear Quadrupole Ion Trap.

Snyder DT, Szalwinski LJ, Schrader RL, Pirro V, Hilger R, Cooks RG.

J Am Soc Mass Spectrom. 2018 Jul;29(7):1345-1354. doi: 10.1007/s13361-018-1920-3. Epub 2018 Mar 9.

PMID:
29524108
19.

Electrophoretic Desalting To Improve Performance in Electrospray Ionization Mass Spectrometry.

Zhang Z, Pulliam CJ, Flick T, Cooks RG.

Anal Chem. 2018 Mar 20;90(6):3856-3862. doi: 10.1021/acs.analchem.7b04529. Epub 2018 Feb 28.

PMID:
29436814
20.

From DESI to the MasSpec Pen: Ambient Ionization Mass Spectrometry for Tissue Analysis and Intrasurgical Cancer Diagnosis.

Brown HM, Pirro V, Cooks RG.

Clin Chem. 2018 Apr;64(4):628-630. doi: 10.1373/clinchem.2017.281923. Epub 2018 Jan 29. No abstract available.

PMID:
29378688
21.

Uncatalyzed, Regioselective Oxidation of Saturated Hydrocarbons in an Ambient Corona Discharge.

Ayrton ST, Jones R, Douce DS, Morris MR, Cooks RG.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):769-773. doi: 10.1002/anie.201711190. Epub 2017 Dec 14.

PMID:
29193616
22.

Feasibility of desorption electrospray ionization mass spectrometry for diagnosis of oral tongue squamous cell carcinoma.

D'Hue C, Moore M, Summerlin DJ, Jarmusch A, Alfaro C, Mantravadi A, Bewley A, Gregory Farwell D, Cooks RG.

Rapid Commun Mass Spectrom. 2018 Jan 30;32(2):133-141. doi: 10.1002/rcm.8019.

23.

Atmospheric pressure neutral reionization mass spectrometry for structural analysis.

Liu P, Zhao P, Cooks RG, Chen H.

Chem Sci. 2017 Sep 1;8(9):6499-6507. doi: 10.1039/c7sc01999h. Epub 2017 Jul 21.

24.

Analysis of human gliomas by swab touch spray-mass spectrometry: applications to intraoperative assessment of surgical margins and presence of oncometabolites.

Pirro V, Llor RS, Jarmusch AK, Alfaro CM, Cohen-Gadol AA, Hattab EM, Cooks RG.

Analyst. 2017 Oct 23;142(21):4058-4066. doi: 10.1039/c7an01334e.

25.

Mass spectrometric directed system for the continuous-flow synthesis and purification of diphenhydramine.

Loren BP, Wleklinski M, Koswara A, Yammine K, Hu Y, Nagy ZK, Thompson DH, Cooks RG.

Chem Sci. 2017 Jun 1;8(6):4363-4370. doi: 10.1039/c7sc00905d. Epub 2017 Apr 19.

26.

Simultaneous and Sequential MS/MS Scan Combinations and Permutations in a Linear Quadrupole Ion Trap.

Snyder DT, Szalwinski LJ, Cooks RG.

Anal Chem. 2017 Oct 17;89(20):11053-11060. doi: 10.1021/acs.analchem.7b03064. Epub 2017 Oct 6.

PMID:
28953354
27.

Forensic Sampling and Analysis from a Single Substrate: Surface-Enhanced Raman Spectroscopy Followed by Paper Spray Mass Spectrometry.

Fedick PW, Bills BJ, Manicke NE, Cooks RG.

Anal Chem. 2017 Oct 17;89(20):10973-10979. doi: 10.1021/acs.analchem.7b02798. Epub 2017 Oct 3.

PMID:
28926701
28.

N-Acetylaspartate and 2-Hydroxyglutarate Assessed in Human Brain Tissue by Mass Spectrometry as Neuronal Markers of Oncogenesis.

Yannell KE, Smith K, Alfaro CM, Jarmusch AK, Pirro V, Cooks RG.

Clin Chem. 2017 Nov;63(11):1766-1767. doi: 10.1373/clinchem.2017.279364. Epub 2017 Sep 6. No abstract available.

29.

Reaction screening and optimization of continuous-flow atropine synthesis by preparative electrospray mass spectrometry.

Falcone CE, Jaman Z, Wleklinski M, Koswara A, Thompson DH, Cooks RG.

Analyst. 2017 Jul 24;142(15):2836-2845. doi: 10.1039/c7an00622e.

PMID:
28703239
30.

Multiple reaction monitoring (MRM)-profiling for biomarker discovery applied to human polycystic ovarian syndrome.

Cordeiro FB, Ferreira CR, Sobreira TJP, Yannell KE, Jarmusch AK, Cedenho AP, Lo Turco EG, Cooks RG.

Rapid Commun Mass Spectrom. 2017 Sep 15;31(17):1462-1470. doi: 10.1002/rcm.7927.

PMID:
28656689
31.

Single Analyzer Neutral Loss Scans in a Linear Quadrupole Ion Trap Using Orthogonal Double Resonance Excitation.

Snyder DT, Cooks RG.

Anal Chem. 2017 Aug 1;89(15):8148-8155. doi: 10.1021/acs.analchem.7b01963. Epub 2017 Jul 12.

PMID:
28644622
32.

Intraoperative assessment of tumor margins during glioma resection by desorption electrospray ionization-mass spectrometry.

Pirro V, Alfaro CM, Jarmusch AK, Hattab EM, Cohen-Gadol AA, Cooks RG.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6700-6705. doi: 10.1073/pnas.1706459114. Epub 2017 Jun 12.

33.

Single Analyzer Precursor Ion Scans in a Linear Quadrupole Ion Trap Using Orthogonal Double Resonance Excitation.

Snyder DT, Cooks RG.

J Am Soc Mass Spectrom. 2017 Sep;28(9):1929-1938. doi: 10.1007/s13361-017-1707-y. Epub 2017 Jun 2.

PMID:
28577288
34.

Reaction Acceleration in Thin Films with Continuous Product Deposition for Organic Synthesis.

Wei Z, Wleklinski M, Ferreira C, Cooks RG.

Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9386-9390. doi: 10.1002/anie.201704520. Epub 2017 Jul 5.

PMID:
28557142
35.

Unique capabilities of AC frequency scanning and its implementation on a Mars Organic Molecule Analyzer linear ion trap.

Snyder DT, Kaplan DA, Danell RM, van Amerom FHW, Pinnick VT, Brinckerhoff WB, Mahaffy PR, Cooks RG.

Analyst. 2017 Jun 21;142(12):2109-2117. doi: 10.1039/c7an00664k. Epub 2017 May 26.

PMID:
28548668
36.

Simultaneous Online Monitoring of Multiple Reactions Using a Miniature Mass Spectrometer.

Pulliam CJ, Bain RM, Osswald HL, Snyder DT, Fedick PW, Ayrton ST, Flick TG, Cooks RG.

Anal Chem. 2017 Jul 5;89(13):6969-6975. doi: 10.1021/acs.analchem.7b00119. Epub 2017 Jun 15.

PMID:
28520396
37.

Jonathan W. Amy and the Amy Facility for Instrumentation Development.

Cooks RG.

Anal Chem. 2017 May 16;89(10):5171-5173. doi: 10.1021/acs.analchem.7b00158. Epub 2017 Apr 26.

PMID:
28406603
38.

Ion Separation in Air Using a Three-Dimensional Printed Ion Mobility Spectrometer.

Hollerbach A, Baird Z, Cooks RG.

Anal Chem. 2017 May 2;89(9):5058-5065. doi: 10.1021/acs.analchem.7b00469. Epub 2017 Apr 13.

PMID:
28383249
39.

Fischer Indole Synthesis in the Gas Phase, the Solution Phase, and at the Electrospray Droplet Interface.

Bain RM, Ayrton ST, Cooks RG.

J Am Soc Mass Spectrom. 2017 Jul;28(7):1359-1364. doi: 10.1007/s13361-017-1597-z. Epub 2017 Feb 13.

PMID:
28194736
40.

Ambient Ionization Mass Spectrometry Measurement of Aminotransferase Activity.

Yan X, Li X, Zhang C, Xu Y, Cooks RG.

J Am Soc Mass Spectrom. 2017 Jun;28(6):1175-1181. doi: 10.1007/s13361-016-1591-x. Epub 2017 Jan 31.

PMID:
28144898
41.

Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS.

Pirro V, Jarmusch AK, Alfaro CM, Hattab EM, Cohen-Gadol AA, Cooks RG.

Analyst. 2017 Jan 26;142(3):449-454. doi: 10.1039/c6an02645a.

PMID:
28112301
42.

Comparison of paper spray mass spectrometry analysis of dried blood spots from devices used for in-field collection of clinical samples.

Yannell KE, Kesely KR, Chien HD, Kissinger CB, Cooks RG.

Anal Bioanal Chem. 2017 Jan;409(1):121-131. doi: 10.1007/s00216-016-9954-5. Epub 2016 Nov 7.

PMID:
27822645
43.

Ion isolation and multigenerational collision-induced dissociation using the inverse Mathieu q scan.

Snyder DT, Cooks RG.

Rapid Commun Mass Spectrom. 2017 Jan 30;31(2):200-206. doi: 10.1002/rcm.7782.

PMID:
27809375
44.

Ion Isolation in a Linear Ion Trap Using Dual Resonance Frequencies.

Snyder DT, Cooks RG.

J Am Soc Mass Spectrom. 2016 Dec;27(12):1906-1913. Epub 2016 Sep 19.

PMID:
27644943
45.

Multigenerational Broadband Collision-Induced Dissociation of Precursor Ions in a Linear Quadrupole Ion Trap.

Snyder DT, Cooks RG.

J Am Soc Mass Spectrom. 2016 Dec;27(12):1914-1921. Epub 2016 Sep 19.

PMID:
27644942
46.

Successive Resonances for Ion Ejection at Arbitrary Frequencies in an Ion Trap.

Snyder DT, Cooks RG.

J Am Soc Mass Spectrom. 2016 Dec;27(12):1922-1928. Epub 2016 Sep 6.

PMID:
27600577
47.

Differential Lipid Profiles of Normal Human Brain Matter and Gliomas by Positive and Negative Mode Desorption Electrospray Ionization - Mass Spectrometry Imaging.

Jarmusch AK, Alfaro CM, Pirro V, Hattab EM, Cohen-Gadol AA, Cooks RG.

PLoS One. 2016 Sep 22;11(9):e0163180. doi: 10.1371/journal.pone.0163180. eCollection 2016.

48.

Multigenerational Collision-Induced Dissociation for Characterization of Organic Compounds.

Snyder DT, Fedick PW, Cooks RG.

Anal Chem. 2016 Oct 4;88(19):9572-9581. Epub 2016 Sep 22.

PMID:
27622856
49.

Organic Reactions in Microdroplets: Reaction Acceleration Revealed by Mass Spectrometry.

Yan X, Bain RM, Cooks RG.

Angew Chem Int Ed Engl. 2016 Oct 10;55(42):12960-12972. doi: 10.1002/anie.201602270. Review.

PMID:
27530279
50.

Chemical profiling of cerebrospinal fluid by multiple reaction monitoring mass spectrometry.

Ferreira CR, Yannell KE, Mollenhauer B, Espy RD, Cordeiro FB, Ouyang Z, Cooks RG.

Analyst. 2016 Sep 21;141(18):5252-5. doi: 10.1039/c6an01618a. Epub 2016 Aug 12.

PMID:
27517482

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