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Quantifying uncertainty about future antimicrobial resistance: Comparing structured expert judgment and statistical forecasting methods.

Colson AR, Megiddo I, Alvarez-Uria G, Gandra S, Bedford T, Morton A, Cooke RM, Laxminarayan R.

PLoS One. 2019 Jul 5;14(7):e0219190. doi: 10.1371/journal.pone.0219190. eCollection 2019.


Ice sheet contributions to future sea-level rise from structured expert judgment.

Bamber JL, Oppenheimer M, Kopp RE, Aspinall WP, Cooke RM.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11195-11200. doi: 10.1073/pnas.1817205116. Epub 2019 May 20.


Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target.

Brown DG, Brown GA, Centrella P, Certel K, Cooke RM, Cuozzo JW, Dekker N, Dumelin CE, Ferguson A, Fiez-Vandal C, Geschwindner S, Guié MA, Habeshian S, Keefe AD, Schlenker O, Sigel EA, Snijder A, Soutter HT, Sundström L, Troast DM, Wiggin G, Zhang J, Zhang Y, Clark MA.

SLAS Discov. 2018 Jun;23(5):429-436. doi: 10.1177/2472555217749847. Epub 2018 Jan 9.


Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals.

Rucktooa P, Cheng RKY, Segala E, Geng T, Errey JC, Brown GA, Cooke RM, Marshall FH, Doré AS.

Sci Rep. 2018 Jan 8;8(1):41. doi: 10.1038/s41598-017-18570-w.


Impact of protein-ligand solvation and desolvation on transition state thermodynamic properties of adenosine A2A ligand binding kinetics.

Deganutti G, Zhukov A, Deflorian F, Federico S, Spalluto G, Cooke RM, Moro S, Mason JS, Bortolato A.

In Silico Pharmacol. 2017 Nov 20;5(1):16. doi: 10.1007/s40203-017-0037-x. eCollection 2017.


Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727.

Robertson N, Rappas M, Doré AS, Brown J, Bottegoni G, Koglin M, Cansfield J, Jazayeri A, Cooke RM, Marshall FH.

Nature. 2018 Jan 3;553(7686):111-114. doi: 10.1038/nature25025.


Probabilistic reasoning about measurements of equilibrium climate sensitivity: combining disparate lines of evidence.

Cooke RM, Wielicki B.

Clim Change. 2018;151(3):541-554. doi: 10.1007/s10584-018-2315-y. Epub 2018 Nov 5.


Structural Mapping of Adenosine Receptor Mutations: Ligand Binding and Signaling Mechanisms.

Jespers W, Schiedel AC, Heitman LH, Cooke RM, Kleene L, van Westen GJP, Gloriam DE, Müller CE, Sotelo E, Gutiérrez-de-Terán H.

Trends Pharmacol Sci. 2018 Jan;39(1):75-89. doi: 10.1016/ Epub 2017 Dec 5. Review.


Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.

Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, Gashi D, Vera L, Marsh M, Jaeger K, Dworkowski F, Panepucci E, Basu S, Skopintsev P, Doré AS, Geng T, Cooke RM, Liang M, Prota AE, Panneels V, Nogly P, Ermler U, Schertler G, Hennig M, Steinmetz MO, Wang M, Standfuss J.

Nat Commun. 2017 Sep 14;8(1):542. doi: 10.1038/s41467-017-00630-4.


Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity.

Cheng RKY, Segala E, Robertson N, Deflorian F, Doré AS, Errey JC, Fiez-Vandal C, Marshall FH, Cooke RM.

Structure. 2017 Aug 1;25(8):1275-1285.e4. doi: 10.1016/j.str.2017.06.012. Epub 2017 Jul 14.


Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist.

Jazayeri A, Rappas M, Brown AJH, Kean J, Errey JC, Robertson NJ, Fiez-Vandal C, Andrews SP, Congreve M, Bortolato A, Mason JS, Baig AH, Teobald I, Doré AS, Weir M, Cooke RM, Marshall FH.

Nature. 2017 Aug 3;548(7665):122. doi: 10.1038/nature23311. Epub 2017 Jul 12.


Crystal structure of the GLP-1 receptor bound to a peptide agonist.

Jazayeri A, Rappas M, Brown AJH, Kean J, Errey JC, Robertson NJ, Fiez-Vandal C, Andrews SP, Congreve M, Bortolato A, Mason JS, Baig AH, Teobald I, Doré AS, Weir M, Cooke RM, Marshall FH.

Nature. 2017 Jun 8;546(7657):254-258. doi: 10.1038/nature22800. Epub 2017 May 31. Erratum in: Nature. 2017 Aug 3;548(7665):122.


Structural insight into allosteric modulation of protease-activated receptor 2.

Cheng RKY, Fiez-Vandal C, Schlenker O, Edman K, Aggeler B, Brown DG, Brown GA, Cooke RM, Dumelin CE, Doré AS, Geschwindner S, Grebner C, Hermansson NO, Jazayeri A, Johansson P, Leong L, Prihandoko R, Rappas M, Soutter H, Snijder A, Sundström L, Tehan B, Thornton P, Troast D, Wiggin G, Zhukov A, Marshall FH, Dekker N.

Nature. 2017 May 4;545(7652):112-115. doi: 10.1038/nature22309. Epub 2017 Apr 26.


Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

Schuetz DA, de Witte WEA, Wong YC, Knasmueller B, Richter L, Kokh DB, Sadiq SK, Bosma R, Nederpelt I, Heitman LH, Segala E, Amaral M, Guo D, Andres D, Georgi V, Stoddart LA, Hill S, Cooke RM, De Graaf C, Leurs R, Frech M, Wade RC, de Lange ECM, IJzerman AP, Müller-Fahrnow A, Ecker GF.

Drug Discov Today. 2017 Jun;22(6):896-911. doi: 10.1016/j.drudis.2017.02.002. Epub 2017 Apr 13. Review.


Intracellular allosteric antagonism of the CCR9 receptor.

Oswald C, Rappas M, Kean J, Doré AS, Errey JC, Bennett K, Deflorian F, Christopher JA, Jazayeri A, Mason JS, Congreve M, Cooke RM, Marshall FH.

Nature. 2016 Dec 15;540(7633):462-465. doi: 10.1038/nature20606. Epub 2016 Dec 7.


Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength.

Segala E, Guo D, Cheng RK, Bortolato A, Deflorian F, Doré AS, Errey JC, Heitman LH, IJzerman AP, Marshall FH, Cooke RM.

J Med Chem. 2016 Jul 14;59(13):6470-9. doi: 10.1021/acs.jmedchem.6b00653. Epub 2016 Jul 1.


Extra-helical binding site of a glucagon receptor antagonist.

Jazayeri A, Doré AS, Lamb D, Krishnamurthy H, Southall SM, Baig AH, Bortolato A, Koglin M, Robertson NJ, Errey JC, Andrews SP, Teobald I, Brown AJ, Cooke RM, Weir M, Marshall FH.

Nature. 2016 May 12;533(7602):274-7. doi: 10.1038/nature17414. Epub 2016 Apr 25.


Evaluation of a Performance-Based Expert Elicitation: WHO Global Attribution of Foodborne Diseases.

Aspinall WP, Cooke RM, Havelaar AH, Hoffmann S, Hald T.

PLoS One. 2016 Mar 1;11(3):e0149817. doi: 10.1371/journal.pone.0149817. eCollection 2016.


Structures of G protein-coupled receptors reveal new opportunities for drug discovery.

Cooke RM, Brown AJ, Marshall FH, Mason JS.

Drug Discov Today. 2015 Nov;20(11):1355-64. doi: 10.1016/j.drudis.2015.08.003. Epub 2015 Aug 22. Review.


Purification of Stabilized GPCRs for Structural and Biophysical Analyses.

Errey JC, Doré AS, Zhukov A, Marshall FH, Cooke RM.

Methods Mol Biol. 2015;1335:1-15. doi: 10.1007/978-1-4939-2914-6_1.


Rating impacts in a multi-stressor world: a quantitative assessment of 50 stressors affecting the Great Lakes.

Smith SD, Mcintyre PB, Halpern BS, Cooke RM, Marino AL, Boyer GL, Buchsbaum A, Burton GA Jr, Campbell LM, Ciborowski JJ, Doran PJ, Infante DM, Johnson LB, Read JG, Rose JB, Rutherford ES, Steinman AD, Allan JD.

Ecol Appl. 2015 Apr;25(3):717-28.


Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A(2A) receptor reconstituted in HDL like particles.

Segala E, Errey JC, Fiez-Vandal C, Zhukov A, Cooke RM.

FEBS Lett. 2015 Jun 4;589(13):1399-405. doi: 10.1016/j.febslet.2015.04.030. Epub 2015 Apr 29.


The aggregation of expert judgment: do good things come to those who weight?

Cooke RM.

Risk Anal. 2015 Jan;35(1):12-5. doi: 10.1111/risa.12353. Epub 2015 Feb 2.


Use of structured expert judgment to forecast invasions by bighead and silver carp in Lake Erie.

Wittmann ME, Cooke RM, Rothlisberger JD, Rutherford ES, Zhang H, Mason DM, Lodge DM.

Conserv Biol. 2015 Feb;29(1):187-97. doi: 10.1111/cobi.12369. Epub 2014 Aug 7.


Out-of-sample validation for structured expert judgment of Asian carp establishment in Lake Erie.

Cooke RM, Wittmann ME, Lodge DM, Rothlisberger JD, Rutherford ES, Zhang H, Mason DM.

Integr Environ Assess Manag. 2014 Oct;10(4):522-8. doi: 10.1002/ieam.1559.


Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

Doré AS, Okrasa K, Patel JC, Serrano-Vega M, Bennett K, Cooke RM, Errey JC, Jazayeri A, Khan S, Tehan B, Weir M, Wiggin GR, Marshall FH.

Nature. 2014 Jul 31;511(7511):557-62. doi: 10.1038/nature13396. Epub 2014 Jul 6.


Using structured expert judgment to assess invasive species prevention: Asian carp and the Mississippi-Great Lakes hydrologic connection.

Wittmann ME, Cooke RM, Rothlisberger JD, Lodge DM.

Environ Sci Technol. 2014 Feb 18;48(4):2150-6. doi: 10.1021/es4043098. Epub 2014 Jan 27.


Incidence rates of surgically treated rhegmatogenous retinal detachment among manual workers, non-manual workers and housewives in Tuscany, Italy.

Curti S, Coggon D, Baldasseroni A, Cooke RM, Fresina M, Campos EC, Semeraro F, Zanardi F, Farioli A, Violante FS, Mattioli S.

Int Arch Occup Environ Health. 2014 Jul;87(5):539-45. doi: 10.1007/s00420-013-0894-5. Epub 2013 Jul 28.


Structure of class B GPCR corticotropin-releasing factor receptor 1.

Hollenstein K, Kean J, Bortolato A, Cheng RK, Doré AS, Jazayeri A, Cooke RM, Weir M, Marshall FH.

Nature. 2013 Jul 25;499(7459):438-43. doi: 10.1038/nature12357. Epub 2013 Jul 17.


Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy.

Cooke RM, Mistry R, Challiss RA, Straub VA.

J Neurosci. 2013 Mar 27;33(13):5626-37. doi: 10.1523/JNEUROSCI.3659-12.2013.


Preparation of purified GPCRs for structural studies.

Cooke RM, Koglin M, Errey JC, Marshall FH.

Biochem Soc Trans. 2013 Feb 1;41(1):185-90. doi: 10.1042/BST20120240.


Carcinoma of the pharynx and tonsils in an occupational cohort of asphalt workers.

Zanardi F, Salvarani R, Cooke RM, Pirastu R, Baccini M, Christiani D, Curti S, Risi A, Barbieri A, Barbieri G, Mattioli S, Violante FS.

Epidemiology. 2013 Jan;24(1):100-3. doi: 10.1097/EDE.0b013e318276cc95.


Model uncertainty in economic impacts of climate change: Bernoulli versus Lotka Volterra dynamics.

Cooke RM.

Integr Environ Assess Manag. 2013 Jan;9(1):2-6. doi: 10.1002/ieam.1316. Epub 2012 Sep 18.


Hidden effectiveness? Results of hand-searching Italian language journals for occupational health interventions.

Mattioli S, Farioli A, Cooke RM, Baldasseroni A, Ruotsalainen J, Placidi D, Curti S, Mancini G, Fierro M, Campo G, Zanardi F, Violante FS.

Occup Environ Med. 2012 Jul;69(7):522-4. doi: 10.1136/oemed-2011-100180. Epub 2012 Mar 23.


Manipulations of spinal cord excitability evoke developmentally-dependent compensatory changes in the lamprey spinal cord.

Cooke RM, Luco S, Parker D.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2012 Jan;198(1):25-41. doi: 10.1007/s00359-011-0683-0. Epub 2011 Oct 29.


Loads of housework? Biomechanical assessments of the upper limbs in women performing common household tasks.

Apostoli P, Sala E, Curti S, Cooke RM, Violante FS, Mattioli S.

Int Arch Occup Environ Health. 2012 May;85(4):421-5. doi: 10.1007/s00420-011-0690-z. Epub 2011 Aug 4.


Prioritizing emerging zoonoses in the Netherlands.

Havelaar AH, van Rosse F, Bucura C, Toetenel MA, Haagsma JA, Kurowicka D, Heesterbeek JH, Speybroeck N, Langelaar MF, van der Giessen JW, Cooke RM, Braks MA.

PLoS One. 2010 Nov 15;5(11):e13965. doi: 10.1371/journal.pone.0013965.


"Is this case of a very rare disease work-related?" A review of reported cases of Pacinian neuroma.

Zanardi F, Cooke RM, Maiorana A, Curti S, Farioli A, Bonfiglioli R, Violante FS, Mattioli S.

Scand J Work Environ Health. 2011 May;37(3):253-8. doi: 10.5271/sjweh.3132. Epub 2010 Nov 17. Review.


Arrhythmia discrimination by physician and defibrillator: importance of atrial channel.

Diemberger I, Martignani C, Biffi M, Frabetti L, Valzania C, Cooke RM, Rapezzi C, Branzi A, Boriani G.

Int J Cardiol. 2012 Jan 26;154(2):134-40. doi: 10.1016/j.ijcard.2010.09.005. Epub 2010 Oct 14.


Trial-generated profiles for implantation of electrical devices in outpatients with heart failure: real-world prevalence and 1-year outcome.

Boriani G, Rapezzi C, Diemberger I, Gonzini L, Gorini M, Lucci D, Sinagra G, Cooke RM, Di Pasquale G, Tavazzi L, Maggioni AP.

J Eval Clin Pract. 2010 Feb;16(1):82-91. doi: 10.1111/j.1365-2753.2008.01118.x. Epub 2009 Oct 27.


Search strings for the study of putative occupational determinants of disease.

Mattioli S, Zanardi F, Baldasseroni A, Schaafsma F, Cooke RM, Mancini G, Fierro M, Santangelo C, Farioli A, Fucksia S, Curti S, Violante FS, Verbeek J.

Occup Environ Med. 2010 Jul;67(7):436-43. doi: 10.1136/oem.2008.044727. Epub 2009 Oct 9. Erratum in: Occup Environ Med. 2010 Nov;67(11):99.


Risk factors for operated carpal tunnel syndrome: a multicenter population-based case-control study.

Mattioli S, Baldasseroni A, Bovenzi M, Curti S, Cooke RM, Campo G, Barbieri PG, Ghersi R, Broccoli M, Cancellieri MP, Colao AM, Dell'omo M, Fateh-Moghadam P, Franceschini F, Fucksia S, Galli P, Gobba F, Lucchini R, Mandes A, Marras T, Sgarrella C, Borghesi S, Fierro M, Zanardi F, Mancini G, Violante FS.

BMC Public Health. 2009 Sep 16;9:343. doi: 10.1186/1471-2458-9-343.


Systemic cardiac amyloidoses: disease profiles and clinical courses of the 3 main types.

Rapezzi C, Merlini G, Quarta CC, Riva L, Longhi S, Leone O, Salvi F, Ciliberti P, Pastorelli F, Biagini E, Coccolo F, Cooke RM, Bacchi-Reggiani L, Sangiorgi D, Ferlini A, Cavo M, Zamagni E, Fonte ML, Palladini G, Salinaro F, Musca F, Obici L, Branzi A, Perlini S.

Circulation. 2009 Sep 29;120(13):1203-12. doi: 10.1161/CIRCULATIONAHA.108.843334. Epub 2009 Sep 14.


Prepublication data sharing.

Toronto International Data Release Workshop Authors, Birney E, Hudson TJ, Green ED, Gunter C, Eddy S, Rogers J, Harris JR, Ehrlich SD, Apweiler R, Austin CP, Berglund L, Bobrow M, Bountra C, Brookes AJ, Cambon-Thomsen A, Carter NP, Chisholm RL, Contreras JL, Cooke RM, Crosby WL, Dewar K, Durbin R, Dyke SO, Ecker JR, El Emam K, Feuk L, Gabriel SB, Gallacher J, Gelbart WM, Granell A, Guarner F, Hubbard T, Jackson SA, Jennings JL, Joly Y, Jones SM, Kaye J, Kennedy KL, Knoppers BM, Kyrpides NC, Lowrance WW, Luo J, MacKay JJ, Martín-Rivera L, McCombie WR, McPherson JD, Miller L, Miller W, Moerman D, Mooser V, Morton CC, Ostell JM, Ouellette BF, Parkhill J, Raina PS, Rawlings C, Scherer SE, Scherer SW, Schofield PN, Sensen CW, Stodden VC, Sussman MR, Tanaka T, Thornton J, Tsunoda T, Valle D, Vuorio EI, Walker NM, Wallace S, Weinstock G, Whitman WB, Worley KC, Wu C, Wu J, Yu J.

Nature. 2009 Sep 10;461(7261):168-70. doi: 10.1038/461168a.


Risk factors for retinal detachment.

Mattioli S, Curti S, De Fazio R, Farioli A, Cooke RM, Zanardi F, Violante FS.

Epidemiology. 2009 May;20(3):465-6. doi: 10.1097/EDE.0b013e31819f1b17. No abstract available.


Incidence rates of surgically treated idiopathic carpal tunnel syndrome in blue- and white-collar workers and housewives in Tuscany, Italy.

Mattioli S, Baldasseroni A, Curti S, Cooke RM, Mandes A, Zanardi F, Farioli A, Buiatti E, Campo G, Violante FS.

Occup Environ Med. 2009 May;66(5):299-304. doi: 10.1136/oem.2008.040212. Epub 2009 Mar 1.


Risk factors for diagnostic delay in acute aortic dissection.

Rapezzi C, Longhi S, Graziosi M, Biagini E, Terzi F, Cooke RM, Quarta C, Sangiorgi D, Ciliberti P, Di Pasquale G, Branzi A.

Am J Cardiol. 2008 Nov 15;102(10):1399-406. doi: 10.1016/j.amjcard.2008.07.013. Epub 2008 Sep 11.


Incidence rates of in-hospital carpal tunnel syndrome in the general population and possible associations with marital status.

Mattioli S, Baldasseroni A, Curti S, Cooke RM, Bena A, de Giacomi G, dell'Omo M, Fateh-Moghadam P, Melani C, Biocca M, Buiatti E, Campo G, Zanardi F, Violante FS.

BMC Public Health. 2008 Oct 28;8:374. doi: 10.1186/1471-2458-8-374.


Physical exertion (lifting) and retinal detachment among people with myopia.

Mattioli S, De Fazio R, Buiatti E, Truffelli D, Zanardi F, Curti S, Cooke RM, Baldasseroni A, Miglietta B, Bonfiglioli R, Tassinari G, Violante FS.

Epidemiology. 2008 Nov;19(6):868-71. doi: 10.1097/EDE.0b013e318187a7da.


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