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Items: 43


The Methyl-CpG-Binding Protein Mbd2 Regulates Susceptibility to Experimental Colitis via Control of CD11c+ Cells and Colonic Epithelium.

Jones GR, Brown SL, Phythian-Adams AT, Ivens AC, Cook PC, MacDonald AS.

Front Immunol. 2020 Feb 14;11:183. doi: 10.3389/fimmu.2020.00183. eCollection 2020.


Macrophages assemble! But do they need IL-4R during schistosomiasis?

Rückerl D, Cook PC.

Eur J Immunol. 2019 Jul;49(7):996-1000. doi: 10.1002/eji.201948158.


The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function.

Bancroft AJ, Levy CW, Jowitt TA, Hayes KS, Thompson S, Mckenzie EA, Ball MD, Dubaissi E, France AP, Bellina B, Sharpe C, Mironov A, Brown SL, Cook PC, S MacDonald A, Thornton DJ, Grencis RK.

Nat Commun. 2019 May 28;10(1):2344. doi: 10.1038/s41467-019-09996-z.


The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.

Svedberg FR, Brown SL, Krauss MZ, Campbell L, Sharpe C, Clausen M, Howell GJ, Clark H, Madsen J, Evans CM, Sutherland TE, Ivens AC, Thornton DJ, Grencis RK, Hussell T, Cunoosamy DM, Cook PC, MacDonald AS.

Nat Immunol. 2019 May;20(5):571-580. doi: 10.1038/s41590-019-0352-y. Epub 2019 Apr 1.


Dynamics of Colon Monocyte and Macrophage Activation During Colitis.

Jones GR, Bain CC, Fenton TM, Kelly A, Brown SL, Ivens AC, Travis MA, Cook PC, MacDonald AS.

Front Immunol. 2018 Nov 27;9:2764. doi: 10.3389/fimmu.2018.02764. eCollection 2018.


Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.

May S, Owen H, Phesse TJ, Greenow KR, Jones GR, Blackwood A, Cook PC, Towers C, Gallimore AM, Williams GT, Stürzl M, Britzen-Laurent N, Sansom OJ, MacDonald AS, Bird AP, Clarke AR, Parry L.

J Pathol. 2018 Jul;245(3):270-282. doi: 10.1002/path.5074. Epub 2018 May 16.


Social Media in Pediatric Orthopaedics.

Lander ST, Sanders JO, Cook PC, O'Malley NT.

J Pediatr Orthop. 2017 Oct/Nov;37(7):e436-e439. doi: 10.1097/BPO.0000000000001032.


Type I interferon is required for T helper (Th) 2 induction by dendritic cells.

Webb LM, Lundie RJ, Borger JG, Brown SL, Connor LM, Cartwright AN, Dougall AM, Wilbers RH, Cook PC, Jackson-Jones LH, Phythian-Adams AT, Johansson C, Davis DM, Dewals BG, Ronchese F, MacDonald AS.

EMBO J. 2017 Aug 15;36(16):2404-2418. doi: 10.15252/embj.201695345. Epub 2017 Jul 17.


Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma.

Grabiec AM, Denny N, Doherty JA, Happonen KE, Hankinson J, Connolly E, Fife ME, Fujimori T, Fujino N, Goenka A, Holden S, Tavernier G, Shah R, Cook PC, MacDonald AS, Niven RM, Dahlbäck B, Fowler SJ, Simpson A, Hussell T.

J Allergy Clin Immunol. 2017 Oct;140(4):1144-1146.e4. doi: 10.1016/j.jaci.2017.03.024. Epub 2017 Apr 12. No abstract available.


Incidence and Complications of Open Hip Preservation Surgery: An ABOS Database Review.

Hedgecock J, Cook PC, Harrast J, Baumhauer JF, Giordano BD.

Orthopedics. 2017 Jan 1;40(1):e109-e116. doi: 10.3928/01477447-20161013-01. Epub 2016 Oct 18.


Dendritic cells in lung immunopathology.

Cook PC, MacDonald AS.

Semin Immunopathol. 2016 Jul;38(4):449-60. doi: 10.1007/s00281-016-0571-3. Epub 2016 Jun 2. Review.


A novel iliotibial band and gluteus maximus tenodesis for the treatment of external coxa saltas in a patient with Ehlers-Danlos syndrome.

Bessette MC, Kenney RJ, Geary MB, Cook PC, Giordano BD.

J Hip Preserv Surg. 2015 Jul 23;2(3):316-7. doi: 10.1093/jhps/hnv050. eCollection 2015 Oct. No abstract available.


Current Concepts in Hip Preservation Surgery: Part II--Rehabilitation.

Adler KL, Cook PC, Geisler PR, Yen YM, Giordano BD.

Sports Health. 2016 Jan-Feb;8(1):57-64. doi: 10.1177/1941738115577621. Epub 2015 Mar 19. Review.


Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.

Zhang X, Cook PC, Zindy E, Williams CJ, Jowitt TA, Streuli CH, MacDonald AS, Redondo-Muñoz J.

Nucleic Acids Res. 2016 Apr 20;44(7):3031-44. doi: 10.1093/nar/gkv1348. Epub 2015 Dec 10.


A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection.

Lundie RJ, Webb LM, Marley AK, Phythian-Adams AT, Cook PC, Jackson-Jones LH, Brown S, Maizels RM, Boon L, O'Keeffe M, MacDonald AS.

Immunol Cell Biol. 2016 Apr;94(4):400-10. doi: 10.1038/icb.2015.114. Epub 2015 Dec 11.


Current Concepts in Hip Preservation Surgery: Part I.

Adler KL, Cook PC, Yen YM, Giordano BD.

Sports Health. 2015 Nov-Dec;7(6):518-26. doi: 10.1177/1941738115587270. Epub 2015 May 18. Review.


A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.

Cook PC, Owen H, Deaton AM, Borger JG, Brown SL, Clouaire T, Jones GR, Jones LH, Lundie RJ, Marley AK, Morrison VL, Phythian-Adams AT, Wachter E, Webb LM, Sutherland TE, Thomas GD, Grainger JR, Selfridge J, McKenzie AN, Allen JE, Fagerholm SC, Maizels RM, Ivens AC, Bird A, MacDonald AS.

Nat Commun. 2015 Apr 24;6:6920. doi: 10.1038/ncomms7920.


Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.

Jones LH, Cook PC, Ivens AC, Thomas GD, Phythian-Adams AT, Allen JE, MacDonald AS.

Int Immunol. 2015 Nov;27(11):589-96. doi: 10.1093/intimm/dxv020. Epub 2015 Apr 20.


CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10.

Prendergast CT, Sanin DE, Cook PC, Mountford AP.

Infect Immun. 2015 Apr;83(4):1418-30. doi: 10.1128/IAI.02831-14. Epub 2015 Jan 26.


The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

Fujimori T, Grabiec AM, Kaur M, Bell TJ, Fujino N, Cook PC, Svedberg FR, MacDonald AS, Maciewicz RA, Singh D, Hussell T.

Mucosal Immunol. 2015 Sep;8(5):1021-1030. doi: 10.1038/mi.2014.129. Epub 2015 Jan 21.


Pediatric orthopedics for the primary care provider. Preface.

Cook PC.

Pediatr Clin North Am. 2014 Dec;61(6):xiii-xiv. doi: 10.1016/j.pcl.2014.09.001. Epub 2014 Oct 1. No abstract available.


Transient synovitis, septic hip, and Legg-Calvé-Perthes disease: an approach to the correct diagnosis.

Cook PC.

Pediatr Clin North Am. 2014 Dec;61(6):1109-18. doi: 10.1016/j.pcl.2014.08.002. Epub 2014 Sep 29. Review.


A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection.

Deaton AM, Cook PC, De Sousa D, Phythian-Adams AT, Bird A, MacDonald AS.

Eur J Immunol. 2014 Jun;44(6):1835-41. doi: 10.1002/eji.201344098. Epub 2014 Mar 25.


Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo.

Cook PC, Jones LH, Jenkins SJ, Wynn TA, Allen JE, MacDonald AS.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9977-82. doi: 10.1073/pnas.1121231109. Epub 2012 Jun 1.


Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling.

Ferret-Bernard S, Castro-Borges W, Dowle AA, Sanin DE, Cook PC, Turner JD, MacDonald AS, Thomas JR, Mountford AP.

J Proteomics. 2012 Jan 4;75(3):938-48. doi: 10.1016/j.jprot.2011.10.010. Epub 2011 Oct 25.


The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production.

Paveley RA, Aynsley SA, Turner JD, Bourke CD, Jenkins SJ, Cook PC, Martinez-Pomares L, Mountford AP.

Int J Parasitol. 2011 Nov;41(13-14):1335-45. doi: 10.1016/j.ijpara.2011.08.005. Epub 2011 Oct 14.


CD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection.

Turner JD, Jenkins GR, Hogg KG, Aynsley SA, Paveley RA, Cook PC, Coles MC, Mountford AP.

PLoS Negl Trop Dis. 2011 Aug;5(8):e1269. doi: 10.1371/journal.pntd.0001269. Epub 2011 Aug 9.


Extension type II pediatric supracondylar humerus fractures: a radiographic outcomes study of closed reduction and cast immobilization.

Camus T, MacLellan B, Cook PC, Leahey JL, Hyndman JC, El-Hawary R.

J Pediatr Orthop. 2011 Jun;31(4):366-71. doi: 10.1097/BPO.0b013e31821addcf.


Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation.

Jenkins SJ, Ruckerl D, Cook PC, Jones LH, Finkelman FD, van Rooijen N, MacDonald AS, Allen JE.

Science. 2011 Jun 10;332(6035):1284-8. doi: 10.1126/science.1204351. Epub 2011 May 12.


Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells.

Cook PC, Aynsley SA, Turner JD, Jenkins GR, Van Rooijen N, Leeto M, Brombacher F, Mountford AP.

PLoS Pathog. 2011 Mar;7(3):e1001323. doi: 10.1371/journal.ppat.1001323. Epub 2011 Mar 17.


Posterior kyphectomy for myelomeningocele with anterior placement of fixation: a retrospective review.

Comstock SA, Cook PC, Leahey JL, El-Hawary R, Hyndman JC.

Clin Orthop Relat Res. 2011 May;469(5):1265-71. doi: 10.1007/s11999-010-1611-2.


CD11c depletion severely disrupts Th2 induction and development in vivo.

Phythian-Adams AT, Cook PC, Lundie RJ, Jones LH, Smith KA, Barr TA, Hochweller K, Anderton SM, Hämmerling GJ, Maizels RM, MacDonald AS.

J Exp Med. 2010 Sep 27;207(10):2089-96. doi: 10.1084/jem.20100734. Epub 2010 Sep 6.


Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells.

Paveley RA, Aynsley SA, Cook PC, Turner JD, Mountford AP.

PLoS Negl Trop Dis. 2009 Oct 13;3(10):e528. doi: 10.1371/journal.pntd.0000528.


Selective attention to the parameters of a physically informed sonic model

Lakatos S, Cook PC, Scavone GP.

J Acoust Soc Am. 2000 May;107(5 Pt 1):L31-6. No abstract available.


Adductor and psoas release for subluxation of the hip in children with spastic cerebral palsy.

Moreau M, Cook PC, Ashton B.

J Pediatr Orthop. 1995 Sep-Oct;15(5):672-6.


Issues in the pediatric athlete.

Cook PC, Leit ME.

Orthop Clin North Am. 1995 Jul;26(3):453-64. Review.


Educational outcomes in teenage pregnancy and parenting programs: results from a demonstration.

Warrick L, Christianson JB, Walruff J, Cook PC.

Fam Plann Perspect. 1993 Jul-Aug;25(4):148-55.


Circuit Court to decide whether post-retirement health benefits are vested.

Cook PC, Braden GC.

Bus Health. 1985 Dec;3(2):54. No abstract available.


Homogeneity of pharmaceutical dispersed systems.

Hersey JA, Cook PC.

J Pharm Pharmacol. 1974 Feb;26(2):126-33. No abstract available.


Rhode Island's water pollution problem.


R I Med J. 1947 Feb;30(2):95-9. No abstract available.


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