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Items: 1 to 50 of 497

1.

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni.

McCusker P, Mian MY, Li G, Olp MD, Tiruveedhula VVNPB, Rashid F, Golani LK, Verma RS, Smith BC, Cook JM, Chan JD.

PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007826. doi: 10.1371/journal.pntd.0007826. eCollection 2019 Nov.

2.

Illuminating the dynamic rare biosphere of the Greenland Ice Sheet's Dark Zone.

Gokul JK, Cameron KA, Irvine-Fynn TDL, Cook JM, Hubbard A, Stibal M, Hegarty M, Mur LAJ, Edwards A.

FEMS Microbiol Ecol. 2019 Dec 1;95(12). pii: fiz177. doi: 10.1093/femsec/fiz177.

PMID:
31697309
3.

The Positive Allosteric Modulator of α2/3-Containing GABAA Receptors, KRM-II-81, Is Active in Pharmaco-Resistant Models of Epilepsy and Reduces Hyperexcitability after Traumatic Brain Injury.

Witkin JM, Li G, Golani LK, Xiong W, Smith JL, Ping X, Rashid F, Jahan R, Cerne R, Cook JM, Jin X.

J Pharmacol Exp Ther. 2020 Jan;372(1):83-94. doi: 10.1124/jpet.119.260968. Epub 2019 Nov 6.

PMID:
31694876
4.

Medication versus trauma-focused psychotherapy for adults with posttraumatic stress disorder: A systematic review and meta-analysis.

Sonis J, Cook JM.

Psychiatry Res. 2019 Dec;282:112637. doi: 10.1016/j.psychres.2019.112637. Epub 2019 Oct 24.

PMID:
31690461
5.

Evaluation of the anti-conflict, reinforcing, and sedative effects of YT-III-31, a ligand functionally selective for α3 subunit-containing GABAA receptors.

Meng Z, Berro LF, Sawyer EK, Rüedi-Bettschen D, Cook JE, Li G, Platt DM, Cook JM, Rowlett JK.

J Psychopharmacol. 2019 Oct 31:269881119882803. doi: 10.1177/0269881119882803. [Epub ahead of print]

PMID:
31670615
6.

Correction to "A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung".

Forkuo GS, Nieman AN, Kodali R, Zahn NM, Li G, Roni MSR, Stephen MR, Harris TW, Jahan R, Guthrie ML, Yu OB, Fisher JL, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA.

Mol Pharm. 2019 Nov 4;16(11):4756. doi: 10.1021/acs.molpharmaceut.9b01053. Epub 2019 Oct 21. No abstract available.

PMID:
31633359
7.

Evaluating Unconscious Bias: Speaker Introductions at an International Oncology Conference.

Duma N, Durani U, Woods CB, Kankeu Fonkoua LA, Cook JM, Wee C, Fuentes HE, Gonzalez-Velez M, Murphy MC, Jain S, Marshall AL, Graff SL, Knoll MA.

J Clin Oncol. 2019 Dec 20;37(36):3538-3545. doi: 10.1200/JCO.19.01608. Epub 2019 Oct 11.

PMID:
31603705
8.

Concerns Regarding a Meta-analysis Comparing Psychotherapy With Medications for Posttraumatic Stress Disorder.

Sonis J, Cook JM.

JAMA Psychiatry. 2019 Oct 2. doi: 10.1001/jamapsychiatry.2019.2921. [Epub ahead of print] No abstract available.

PMID:
31577331
9.

Posttraumatic stress symptom courses in U.S. military veterans: A seven-year, nationally representative, prospective cohort study.

Mota NP, Cook JM, Smith NB, Tsai J, Harpaz-Rotem I, Krystal JH, Southwick SM, Pietrzak RH.

J Psychiatr Res. 2019 Dec;119:23-31. doi: 10.1016/j.jpsychires.2019.09.005. Epub 2019 Sep 12.

PMID:
31546045
10.

The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81.

Witkin JM, Ping X, Cerne R, Mouser C, Jin X, Hobbs J, Tiruveedhula VVNPB, Li G, Jahan R, Rashid F, Kumar Golani L, Cook JM, Smith JL.

Brain Res. 2019 Nov 1;1722:146356. doi: 10.1016/j.brainres.2019.146356. Epub 2019 Jul 29. Review.

PMID:
31369732
11.

Trauma training: Competencies, initiatives, and resources.

Cook JM, Newman E, Simiola V.

Psychotherapy (Chic). 2019 Sep;56(3):409-421. doi: 10.1037/pst0000233.

PMID:
31282716
12.

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles.

Prevot TD, Li G, Vidojevic A, Misquitta KA, Fee C, Santrac A, Knutson DE, Stephen MR, Kodali R, Zahn NM, Arnold LA, Scholze P, Fisher JL, Marković BD, Banasr M, Cook JM, Savic M, Sibille E.

Mol Neuropsychiatry. 2019 Apr;5(2):84-97. doi: 10.1159/000496086. Epub 2019 Jan 23.

13.

Randomized Controlled Trial of Imagery Rehearsal for Posttraumatic Nightmares in Combat Veterans.

Harb GC, Cook JM, Phelps AJ, Gehrman PR, Forbes D, Localio R, Harpaz-Rotem I, Gur RC, Ross RJ.

J Clin Sleep Med. 2019 May 15;15(5):757-767. doi: 10.5664/jcsm.7770.

PMID:
31053215
14.

Glacier Algae: A Dark Past and a Darker Future.

Williamson CJ, Cameron KA, Cook JM, Zarsky JD, Stibal M, Edwards A.

Front Microbiol. 2019 Apr 4;10:524. doi: 10.3389/fmicb.2019.00524. eCollection 2019. Review.

15.

Adoption by VA Residential Programs of Two Evidence-Based Psychotherapies for PTSD: Effect on Patient Outcomes.

Cook JM, Schnurr PP, Simiola V, Thompson R, Hoff R, Harpaz-Rotem I.

Psychiatr Serv. 2019 Jul 1;70(7):553-560. doi: 10.1176/appi.ps.201800338. Epub 2019 Apr 10.

PMID:
30966944
16.

Insight into Novel Treatment for Cognitive Dysfunctions across Disorders.

Prevot TD, Li G, Cook JM, Sibille E.

ACS Chem Neurosci. 2019 May 15;10(5):2088-2090. doi: 10.1021/acschemneuro.9b00148. Epub 2019 Mar 28.

PMID:
30920790
17.

Use of Reflective Journaling to Understand Decision Making Regarding Two Evidence-Based Psychotherapies for PTSD: Practice Implications.

Cook JM, Simiola V, McCarthy E, Ellis A, Wiltsey Stirman S.

Pract Innov (Wash D C). 2018 Sep;3(3):153-167. doi: 10.1037/pri0000070. Epub 2018 Jul 19.

18.

Measuring and Visualizing Solar UV for a Wide Range of Atmospheric Conditions on Hawai'i Island.

Mims Iii FM, McGonigle AJS, Wilkes TC, Parisi AV, Grant WB, Cook JM, Pering TD.

Int J Environ Res Public Health. 2019 Mar 19;16(6). pii: E997. doi: 10.3390/ijerph16060997.

19.

GABAA Receptor Subtypes and the Abuse-Related Effects of Ethanol in Rhesus Monkeys: Experiments with Selective Positive Allosteric Modulators.

Berro LF, Rüedi-Bettschen D, Cook JE, Golani LK, Li G, Jahan R, Rashid F, Cook JM, Rowlett JK, Platt DM.

Alcohol Clin Exp Res. 2019 May;43(5):791-802. doi: 10.1111/acer.14000. Epub 2019 Apr 8.

PMID:
30861153
20.

The α2,3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats.

Witkin JM, Cerne R, Davis PG, Freeman KB, do Carmo JM, Rowlett JK, Methuku KR, Okun A, Gleason SD, Li X, Krambis MJ, Poe M, Li G, Schkeryantz JM, Jahan R, Yang L, Guo W, Golani LK, Anderson WH, Catlow JT, Jones TM, Porreca F, Smith JL, Knopp KL, Cook JM.

Pharmacol Biochem Behav. 2019 May;180:22-31. doi: 10.1016/j.pbb.2019.02.013. Epub 2019 Feb 27.

PMID:
30825491
21.

Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.

Kallay L, Keskin H, Ross A, Rupji M, Moody OA, Wang X, Li G, Ahmed T, Rashid F, Stephen MR, Cottrill KA, Nuckols TA, Xu M, Martinson DE, Tranghese F, Pei Y, Cook JM, Kowalski J, Taylor MD, Jenkins A, Pomeranz Krummel DA, Sengupta S.

J Neurooncol. 2019 May;142(3):411-422. doi: 10.1007/s11060-019-03115-0. Epub 2019 Feb 6.

22.

MIDD0301 - A first-in-class anti-inflammatory asthma drug targets GABAA receptors without causing systemic immune suppression.

Zahn NM, Huber AT, Mikulsky BN, Stepanski ME, Kehoe AS, Li G, Schussman M, Rashid Roni MS, Kodali R, Cook JM, Stafford DC, Steeber DA, Arnold LA.

Basic Clin Pharmacol Toxicol. 2019 Jul;125(1):75-84. doi: 10.1111/bcpt.13206. Epub 2019 Feb 21.

PMID:
30694594
23.

Zolpidem Activation of Alpha 1-Containing GABAA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons.

Neumann E, Rudolph U, Knutson DE, Li G, Cook JM, Hentschke H, Antkowiak B, Drexler B.

Front Pharmacol. 2019 Jan 9;9:1523. doi: 10.3389/fphar.2018.01523. eCollection 2018.

24.

α5GABAA subunit-containing receptors and sweetened alcohol cue-induced reinstatement and active sweetened alcohol self-administration in male rats.

Chandler CM, Reeves-Darby J, Jones SA, McDonald JA, Li G, Rahman MT, Cook JM, Platt DM.

Psychopharmacology (Berl). 2019 Jun;236(6):1797-1806. doi: 10.1007/s00213-018-5163-6. Epub 2019 Jan 12.

PMID:
30637435
25.

Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of α6 GABAA receptors.

Vasović D, Divović B, Treven M, Knutson DE, Steudle F, Scholze P, Obradović A, Fabjan J, Brković B, Sieghart W, Ernst M, Cook JM, Savić MM.

Eur J Pain. 2019 May;23(5):973-984. doi: 10.1002/ejp.1365. Epub 2019 Feb 4.

PMID:
30633839
26.

Which patients initiate cognitive processing therapy and prolonged exposure in department of veterans affairs PTSD clinics?

Rosen CS, Bernardy NC, Chard KM, Clothier B, Cook JM, Crowley J, Eftekhari A, Kehle-Forbes SM, Mohr DC, Noorbaloochi S, Orazem RJ, Ruzek JI, Schnurr PP, Smith BN, Sayer NA.

J Anxiety Disord. 2019 Mar;62:53-60. doi: 10.1016/j.janxdis.2018.11.003. Epub 2018 Nov 20.

PMID:
30550959
27.

Two's company, three's a crowd: co-occurring pollinators and parasite species in Breynia oblongifolia (Phyllanthaceae).

Finch JTD, Power SA, Welbergen JA, Cook JM.

BMC Evol Biol. 2018 Dec 14;18(1):193. doi: 10.1186/s12862-018-1314-y.

28.

Pre-operative right ventricular echocardiographic parameters associated with short-term outcomes and long-term mortality after CABG.

Chowdhury MA, Cook JM, Moukarbel GV, Ashtiani S, Schwann TA, Bonnell MR, Cooper CJ, Khouri SJ.

Echo Res Pract. 2018 Dec 1;5(4):155-166. doi: 10.1530/ERP-18-0041.

29.

A novel GABAA receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo.

Yocum GT, Perez-Zoghbi JF, Danielsson J, Kuforiji AS, Zhang Y, Li G, Rashid Roni MS, Kodali R, Stafford DC, Arnold LA, Cook JM, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2019 Feb 1;316(2):L385-L390. doi: 10.1152/ajplung.00356.2018. Epub 2018 Nov 29.

30.

Posttraumatic Stress Disorder in Older Adults: A Conceptual Review.

Pless Kaiser A, Cook JM, Glick DM, Moye J.

Clin Gerontol. 2019 Jul-Sep;42(4):359-376. doi: 10.1080/07317115.2018.1539801. Epub 2018 Nov 13.

PMID:
30422749
31.

Provider general attitudes versus specific perceptions of evidence-based psychotherapies for PTSD.

Cook JM, Thompson R, Simiola V, Wiltsey Stirman S, Schnurr PP.

Psychol Serv. 2020 Feb;17(1):46-53. doi: 10.1037/ser0000280. Epub 2018 Sep 27.

PMID:
30265069
32.

Trauma and Aging.

Cook JM, Simiola V.

Curr Psychiatry Rep. 2018 Sep 7;20(10):93. doi: 10.1007/s11920-018-0943-6. Review.

PMID:
30194546
33.

Deficiencies in Natural Killer Cell Numbers, Expansion, and Function at the Pre-Neoplastic Stage of Pancreatic Cancer by KRAS Mutation in the Pancreas of Obese Mice.

Kaur K, Chang HH, Topchyan P, Cook JM, Barkhordarian A, Eibl G, Jewett A.

Front Immunol. 2018 Jun 21;9:1229. doi: 10.3389/fimmu.2018.01229. eCollection 2018.

34.

Attaining in vivo selectivity of positive modulation of α3βγ2 GABAA receptors in rats: A hard task!

Batinić B, Stanković T, Stephen MR, Kodali R, Tiruveedhula VV, Li G, Scholze P, Marković BD, Obradović AL, Ernst M, Cook JM, Savić MM.

Eur Neuropsychopharmacol. 2018 Aug;28(8):903-914. doi: 10.1016/j.euroneuro.2018.05.014. Epub 2018 Jun 19.

PMID:
29891214
35.

The Influence of Team Functioning and Workload on Sustainability of Trauma-Focused Evidence-Based Psychotherapies.

Mohr DC, Rosen CS, Schnurr PP, Orazem RJ, Noorbaloochi S, Clothier BA, Eftekhari A, Bernardy NC, Chard KM, Crowley JJ, Cook JM, Kehle-Forbes SM, Ruzek JI, Sayer NA.

Psychiatr Serv. 2018 Aug 1;69(8):879-886. doi: 10.1176/appi.ps.201700432. Epub 2018 May 25.

PMID:
29793398
36.

Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABAA receptors: Improved bioavailability enhances anticonvulsant efficacy.

Witkin JM, Smith JL, Ping X, Gleason SD, Poe MM, Li G, Jin X, Hobbs J, Schkeryantz JM, McDermott JS, Alatorre AI, Siemian JN, Cramer JW, Airey DC, Methuku KR, Tiruveedhula VVNPB, Jones TM, Crawford J, Krambis MJ, Fisher JL, Cook JM, Cerne R.

Neuropharmacology. 2018 Jul 15;137:332-343. doi: 10.1016/j.neuropharm.2018.05.006. Epub 2018 May 3.

PMID:
29778948
37.

Different Benzodiazepines Bind with Distinct Binding Modes to GABAA Receptors.

Elgarf AA, Siebert DCB, Steudle F, Draxler A, Li G, Huang S, Cook JM, Ernst M, Scholze P.

ACS Chem Biol. 2018 Aug 17;13(8):2033-2039. doi: 10.1021/acschembio.8b00144. Epub 2018 Jul 23.

38.

Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABAA Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys.

Duke AN, Meng Z, Platt DM, Atack JR, Dawson GR, Reynolds DS, Tiruveedhula VVNPB, Li G, Stephen MR, Sieghart W, Cook JM, Rowlett JK.

J Pharmacol Exp Ther. 2018 Jul;366(1):145-157. doi: 10.1124/jpet.118.249250. Epub 2018 May 2.

39.

An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors.

Methuku KR, Li X, Cerne R, Gleason SD, Schkeryantz JM, Tiruveedhula VVNPB, Golani LK, Li G, Poe MM, Rahman MT, Cook JM, Fisher JL, Witkin JM.

Pharmacol Biochem Behav. 2018 Jul;170:9-13. doi: 10.1016/j.pbb.2018.04.009. Epub 2018 Apr 30.

PMID:
29715490
40.

Elevated atmospheric carbon dioxide concentrations promote ant tending of aphids.

Kremer JMM, Nooten SS, Cook JM, Ryalls JMW, Barton CVM, Johnson SN.

J Anim Ecol. 2018 Sep;87(5):1475-1483. doi: 10.1111/1365-2656.12842. Epub 2018 May 17.

PMID:
29700820
41.
42.

A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung.

Forkuo GS, Nieman AN, Kodali R, Zahn NM, Li G, Rashid Roni MS, Stephen MR, Harris TW, Jahan R, Guthrie ML, Yu OB, Fisher JL, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA.

Mol Pharm. 2018 May 7;15(5):1766-1777. doi: 10.1021/acs.molpharmaceut.7b01013. Epub 2018 Apr 2. Erratum in: Mol Pharm. 2019 Nov 4;16(11):4756.

43.

Measuring Use of Evidence-Based Psychotherapy for PTSD in VA Residential Treatment Settings with Clinician Survey and Electronic Medical Record Templates.

Shiner B, Leonard Westgate C, Simiola V, Thompson R, Schnurr PP, Cook JM.

Mil Med. 2018 Sep 1;183(9-10):e539-e546. doi: 10.1093/milmed/usy008.

44.

Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability.

Knutson DE, Kodali R, Divović B, Treven M, Stephen MR, Zahn NM, Dobričić V, Huber AT, Meirelles MA, Verma RS, Wimmer L, Witzigmann C, Arnold LA, Chiou LC, Ernst M, Mihovilovic MD, Savić MM, Sieghart W, Cook JM.

J Med Chem. 2018 Mar 22;61(6):2422-2446. doi: 10.1021/acs.jmedchem.7b01664. Epub 2018 Mar 6.

45.

Assessment and Treatment Considerations for Post Traumatic Stress Disorder at End of Life.

Glick DM, Cook JM, Moye J, Kaiser AP.

Am J Hosp Palliat Care. 2018 Aug;35(8):1133-1139. doi: 10.1177/1049909118756656. Epub 2018 Feb 20. Review.

46.

Chemical camouflage: a key process in shaping an ant-treehopper and fig-fig wasp mutualistic network.

Wang B, Lu M, Cook JM, Yang DR, Dunn DW, Wang RW.

Sci Rep. 2018 Jan 30;8(1):1833. doi: 10.1038/s41598-018-20310-7.

47.

Negative allosteric modulation of alpha 5-containing GABAA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice.

Xu NZ, Ernst M, Treven M, Cerne R, Wakulchik M, Li X, Jones TM, Gleason SD, Morrow D, Schkeryantz JM, Rahman MT, Li G, Poe MM, Cook JM, Witkin JM.

Psychopharmacology (Berl). 2018 Apr;235(4):1151-1161. doi: 10.1007/s00213-018-4832-9. Epub 2018 Jan 26.

PMID:
29374303
48.

Smartphone Spectrometers.

McGonigle AJS, Wilkes TC, Pering TD, Willmott JR, Cook JM, Mims FM, Parisi AV.

Sensors (Basel). 2018 Jan 14;18(1). pii: E223. doi: 10.3390/s18010223. Review.

49.

Total Synthesis of Sarpagine-Related Bioactive Indole Alkaloids.

Rahman MT, Deschamps JR, Imler GH, Cook JM.

Chemistry. 2018 Feb 16;24(10):2354-2359. doi: 10.1002/chem.201705575. Epub 2018 Jan 23.

PMID:
29244896
50.

Low-cost 3D printed 1  nm resolution smartphone sensor-based spectrometer: instrument design and application in ultraviolet spectroscopy.

Wilkes TC, McGonigle AJS, Willmott JR, Pering TD, Cook JM.

Opt Lett. 2017 Nov 1;42(21):4323-4326. doi: 10.1364/OL.42.004323.

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