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The relative importance of factors predicting outcome for myeloma patients at different ages: results from 3894 patients in the Myeloma XI trial.

Pawlyn C, Cairns D, Kaiser M, Striha A, Jones J, Shah V, Jenner M, Drayson M, Owen R, Gregory W, Cook G, Morgan G, Jackson G, Davies F.

Leukemia. 2019 Oct 14. doi: 10.1038/s41375-019-0595-5. [Epub ahead of print]


Inhalable Dry Powder of Bedaquiline for Pulmonary Tuberculosis: In Vitro Physicochemical Characterization, Antimicrobial Activity and Safety Studies.

Momin MAM, Rangnekar B, Sinha S, Cheung CY, Cook GM, Das SC.

Pharmaceutics. 2019 Oct 1;11(10). pii: E502. doi: 10.3390/pharmaceutics11100502.


Tackling tuberculosis in the indigenous people of New Zealand.

Aung HL, Devine TJ, Mulholland CV, Arcus VL, Cook GM.

Lancet Public Health. 2019 Oct;4(10):e496. doi: 10.1016/S2468-2667(19)30180-X. No abstract available.


Hydration Interventions for older people living in residential and nursing care homes: overview of the literature.

Cook G, Hodgson P, Thompson J, Bainbridge L, Johnson A, Storey P.

Br Med Bull. 2019 Sep 26. pii: ldz027. doi: 10.1093/bmb/ldz027. [Epub ahead of print]


Microtiter Screening Reveals Oxygen-Dependent Antimicrobial Activity of Natural Products Against Mastitis-Causing Bacteria.

Ferguson SA, Menorca A, Van Zuylen EM, Cheung CY, McConnell MA, Rennison D, Brimble MA, Bodle K, McDougall S, Cook GM, Heikal A.

Front Microbiol. 2019 Aug 28;10:1995. doi: 10.3389/fmicb.2019.01995. eCollection 2019.


Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection.

Hasenoehrl EJ, Rae Sajorda D, Berney-Meyer L, Johnson S, Tufariello JM, Fuhrer T, Cook GM, Jacobs WR Jr, Berney M.

Nat Commun. 2019 Sep 16;10(1):4215. doi: 10.1038/s41467-019-12224-3.


Trial re-investment to build better research for better impact.

Fox TA, Horne GA, Craddock C, Cook G, O'Brien S, Fox S, Hockaday A, Silk G, Hillmen P.

Lancet. 2019 Aug 24;394(10199):635-636. doi: 10.1016/S0140-6736(19)31363-7. No abstract available.


CAR-T cell therapy for multiple myeloma: a consensus statement from The European Myeloma Network.

Moreau P, Sonneveld P, Boccadoro M, Cook G, Mateos MV, Nahi H, Goldschmidt H, Dimopoulos MA, Lucio P, Bladé J, Delforge M, Hajek R, Ludwig H, Facon T, San Miguel JF, Einsele H.

Haematologica. 2019 Aug 22. pii: haematol.2019.224204. doi: 10.3324/haematol.2019.224204. [Epub ahead of print]


PSMA PET/CT imaging for primary staging of intermediate and high-risk prostate cancer.

Cook GJR, Kulkarni M, Warbey VS.

BJU Int. 2019 Sep;124(3):357-358. doi: 10.1111/bju.14856. No abstract available.


Staging FDG PET-CT changes management in patients with gastric adenocarcinoma who are eligible for radical treatment.

Bosch KD, Chicklore S, Cook GJ, Davies AR, Kelly M, Gossage JA, Baker CR.

Eur J Nucl Med Mol Imaging. 2019 Aug 3. doi: 10.1007/s00259-019-04429-x. [Epub ahead of print]


The effect of a novel Bayesian penalised likelihood PET reconstruction algorithm on the assessment of malignancy risk in solitary pulmonary nodules according to the British Thoracic Society guidelines.

Murphy DJ, Royle L, Chalampalakis Z, Alves L, Martins N, Bassett P, Breen R, Nair A, Bille A, Chicklore S, Cook GJ, Subesinghe M.

Eur J Radiol. 2019 Aug;117:149-155. doi: 10.1016/j.ejrad.2019.06.005. Epub 2019 Jun 10.


International prevalence and risk factors evaluation for drug-resistant Streptococcus pneumoniae pneumonia.

Aliberti S, Cook GS, Babu BL, Reyes LF, H Rodriguez A, Sanz F, Soni NJ, Anzueto A, Faverio P, Sadud RF, Muhammad I, Prat C, Vendrell E, Neves J, Kaimakamis E, Feneley A, Swarnakar R, Franzetti F, Carugati M, Morosi M, Monge E, Restrepo MI; GLIMP investigators.

J Infect. 2019 Oct;79(4):300-311. doi: 10.1016/j.jinf.2019.07.004. Epub 2019 Jul 9.


Bismuth-Catalyzed Synthesis of 2-Substituted Quinazolinones.

Vemula SR, Kumar D, Cook GR.

Tetrahedron Lett. 2018 Oct 17;59(42):3801-3805. doi: 10.1016/j.tetlet.2018.09.014. Epub 2018 Sep 7.


The synthesis and evaluation of quinolinequinones as anti-mycobacterial agents.

Santoso KT, Menorca A, Cheung CY, Cook GM, Stocker BL, Timmer MSM.

Bioorg Med Chem. 2019 Aug 15;27(16):3532-3545. doi: 10.1016/j.bmc.2019.06.002. Epub 2019 Jun 1.


Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21.

Müller LME, Holmes M, Michael JL, Scott GB, West EJ, Scott KJ, Parrish C, Hall K, Stäble S, Jennings VA, Cullen M, McConnell S, Langton C, Tidswell EL, Shafren D, Samson A, Harrington KJ, Pandha H, Ralph C, Kelly RJ, Cook G, Melcher AA, Errington-Mais F.

J Immunother Cancer. 2019 Jul 1;7(1):164. doi: 10.1186/s40425-019-0632-y.


Diverse hydrogen production and consumption pathways influence methane production in ruminants.

Greening C, Geier R, Wang C, Woods LC, Morales SE, McDonald MJ, Rushton-Green R, Morgan XC, Koike S, Leahy SC, Kelly WJ, Cann I, Attwood GT, Cook GM, Mackie RI.

ISME J. 2019 Oct;13(10):2617-2632. doi: 10.1038/s41396-019-0464-2. Epub 2019 Jun 26.


Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum.

Petri J, Nakatani Y, Montgomery MG, Ferguson SA, Aragão D, Leslie AGW, Heikal A, Walker JE, Cook GM.

Open Biol. 2019 Jun 28;9(6):190066. doi: 10.1098/rsob.190066. Epub 2019 Jun 26.


Housing options for the future: Older people's preferences and views on villages with care and support.

Aitken D, Cook G, Lawson A.

Health Soc Care Community. 2019 Sep;27(5):e769-e780. doi: 10.1111/hsc.12805. Epub 2019 Jun 25.


Daratumumab-based regimens are highly effective and well tolerated in relapsed or refractory multiple myeloma regardless of patient age: subgroup analysis of the phase 3 CASTOR and POLLUX studies.

Mateos MV, Spencer A, Nooka AK, Pour L, Weisel K, Cavo M, Laubach JP, Cook G, Iida S, Benboubker L, Usmani SZ, Yoon SS, Bahlis NJ, Chiu C, Ukropec J, Schecter JM, Qin X, O' Rourke L, Dimopoulos MA.

Haematologica. 2019 Jun 20. pii: haematol.2019.217448. doi: 10.3324/haematol.2019.217448. [Epub ahead of print]


A case of autonomic failure in post-craniectomy syndrome of the trephined.

Beeler MB, Malone TR, Boulter JH, Bell RS, Rosner MK, Cook GA.

Clin Auton Res. 2019 Jun 19. doi: 10.1007/s10286-019-00617-9. [Epub ahead of print] No abstract available.


Assessment of the Spatial Heterogeneity of Breast Cancers: Associations Between Computed Tomography and Immunohistochemistry.

Woolf DK, Li SP, Detre S, Liu A, Gogbashian A, Simcock IC, Stirling J, Kosmin M, Cook GJ, Siddique M, Dowsett M, Makris A, Goh V.

Biomark Cancer. 2019 Jun 4;11:1179299X19851513. doi: 10.1177/1179299X19851513. eCollection 2019.


What can artificial intelligence teach us about the molecular mechanisms underlying disease?

Cook GJR, Goh V.

Eur J Nucl Med Mol Imaging. 2019 Jun 12. doi: 10.1007/s00259-019-04370-z. [Epub ahead of print]


Non-invasive classification of non-small cell lung cancer: a comparison between random forest models utilising radiomic and semantic features.

Bashir U, Kawa B, Siddique M, Mak SM, Nair A, Mclean E, Bille A, Goh V, Cook G.

Br J Radiol. 2019 Jul;92(1099):20190159. doi: 10.1259/bjr.20190159. Epub 2019 Jun 5.


Utilization of CRISPR Interference To Validate MmpL3 as a Drug Target in Mycobacterium tuberculosis.

McNeil MB, Cook GM.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00629-19. doi: 10.1128/AAC.00629-19. Print 2019 Aug.


UK guidelines on 18F-fluciclovine PET/CT in prostate cancer imaging.

Afaq A, Gleeson F, Scarsbrook A, Bradley K, Subesinghe M, Macpherson R, Haroon A, Patel N, Chua S, Wong WL, Vinjamuri S, Warbey VS, Cook GJ, Bomanji J.

Nucl Med Commun. 2019 Jul;40(7):662-674. doi: 10.1097/MNM.0000000000001030.


Loco-regional staging of malignant pleural mesothelioma by integrated 18F-FDG PET/MRI.

Murphy DJ, Mak SM, Mallia A, Jeljeli S, Stirling JJ, Goh V, Bille A, Cook GJR.

Eur J Radiol. 2019 Jun;115:46-52. doi: 10.1016/j.ejrad.2019.04.003. Epub 2019 Apr 5.


Genomewide Profiling of the Enterococcus faecalis Transcriptional Response to Teixobactin Reveals CroRS as an Essential Regulator of Antimicrobial Tolerance.

Darnell RL, Knottenbelt MK, Todd Rose FO, Monk IR, Stinear TP, Cook GM.

mSphere. 2019 May 8;4(3). pii: e00228-19. doi: 10.1128/mSphere.00228-19.


Rapidly tunable HIP treated Cr:ZnSe narrow-linewidth laser.

Turner EJ, McDaniel SA, Tabiryan N, Cook G.

Opt Express. 2019 Apr 29;27(9):12282-12288. doi: 10.1364/OE.27.012282.


Minimally Invasive Pulmonary Artery Aneurysm Repair Through a Left Anterior Minithoracotomy-an Alternative Approach.

Rahman S, Cook G, Zheng J, Rehman A.

Innovations (Phila). 2019 Aug;14(4):353-356. doi: 10.1177/1556984519841284. Epub 2019 May 3.


Agricultural Origins of a Highly Persistent Lineage of Vancomycin-Resistant Enterococcus faecalis in New Zealand.

Rushton-Green R, Darnell RL, Taiaroa G, Carter GP, Cook GM, Morgan XC.

Appl Environ Microbiol. 2019 Jun 17;85(13). pii: e00137-19. doi: 10.1128/AEM.00137-19. Print 2019 Jul 1.


MRI heterogeneity analysis for prediction of recurrence and disease free survival in anal cancer.

Owczarczyk K, Prezzi D, Cascino M, Kozarski R, Gaya A, Siddique M, Cook GJ, Glynne-Jones R, Goh V.

Radiother Oncol. 2019 May;134:119-126. doi: 10.1016/j.radonc.2019.01.022. Epub 2019 Feb 7.


Sequential measurement of δ15 N, δ13 C and δ34 S values in archaeological bone collagen at the Scottish Universities Environmental Research Centre (SUERC): A new analytical frontier.

Sayle KL, Brodie CR, Cook GT, Hamilton WD.

Rapid Commun Mass Spectrom. 2019 Aug 15;33(15):1258-1266. doi: 10.1002/rcm.8462.


Patient-Reported Outcome Results From the Open-Label, Randomized Phase III Myeloma X Trial Evaluating Salvage Autologous Stem-Cell Transplantation in Relapsed Multiple Myeloma.

Ahmedzai SH, Snowden JA, Ashcroft AJ, Cairns DA, Williams C, Hockaday A, Cavenagh JD, Ademokun D, Tholouli E, Allotey D, Dhanapal V, Jenner M, Yong K, Cavet J, Hunter H, Bird JM, Pratt G, Parrish C, Brown JM, Morris TCM, Cook G; National Cancer Research Institute Haemato-Oncology Clinical Studies Group.

J Clin Oncol. 2019 Jul 1;37(19):1617-1628. doi: 10.1200/JCO.18.01006. Epub 2019 Apr 10.


Characteristics of Behcet's Disease in the American Southwest.

Muruganandam M, Rolle NA, Sibbitt WL Jr, Cook GB, Emil NS, Fangtham M, Reiter KJ, Bankhurst AD.

Semin Arthritis Rheum. 2019 Oct;49(2):296-302. doi: 10.1016/j.semarthrit.2019.03.003. Epub 2019 Mar 9.


The Home Visit Rating Scales: Revised, restructured, and revalidated.

Roggman LA, Cook GA, Innocenti MS, Jump Norman VK, Boyce LK, Olson TL, Christiansen K, Peterson CA.

Infant Ment Health J. 2019 May;40(3):315-330. doi: 10.1002/imhj.21781. Epub 2019 Apr 1.


Anemia is a poor prognostic factor for stage I non-small cell lung cancer (NSCLC) patients treated with Stereotactic Body Radiation Therapy (SBRT).

Pathak RS, Pantarotto JR, Cook G, Holmes O, Cross P, MacRae RM.

Clin Transl Radiat Oncol. 2019 Jan 24;16:28-33. doi: 10.1016/j.ctro.2019.01.003. eCollection 2019 May.


Exploratory radiomic features from integrated 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging are associated with contemporaneous metastases in oesophageal/gastroesophageal cancer.

Baiocco S, Sah BR, Mallia A, Kelly-Morland C, Neji R, Stirling JJ, Jeljeli S, Bevilacqua A, Cook GJR, Goh V.

Eur J Nucl Med Mol Imaging. 2019 Jul;46(7):1478-1484. doi: 10.1007/s00259-019-04306-7. Epub 2019 Mar 27.


Measurement of 18F-FDG PET tumor heterogeneity improves early assessment of response to bevacizumab compared with the standard size and uptake metrics in a colorectal cancer model.

Bashir U, Weeks A, Goda JS, Siddique M, Goh V, Cook GJ.

Nucl Med Commun. 2019 Jun;40(6):611-617. doi: 10.1097/MNM.0000000000000992.


Adaptive statistical iterative reconstruction (ASIR) affects CT radiomics quantification in primary colorectal cancer.

Prezzi D, Owczarczyk K, Bassett P, Siddique M, Breen DJ, Cook GJR, Goh V.

Eur Radiol. 2019 Oct;29(10):5227-5235. doi: 10.1007/s00330-019-06073-3. Epub 2019 Mar 18.


Reply: Relevance of Measurement Uncertainty for Quantitative Response Assessment of Breast Cancer Bone Metastases with 18F-Fluoride.

Azad G, Siddique M, Taylor B, Green A, O'Doherty J, Gariani J, Blake G, Mansi J, Goh V, Cook G.

J Nucl Med. 2019 Apr;60(4):569. doi: 10.2967/jnumed.119.226555. Epub 2019 Mar 8. No abstract available.


Correction: Management of relapsed and refractory multiple myeloma: novel agents, antibodies, immunotherapies and beyond.

Chim CS, Kumar SK, Orlowski RZ, Cook G, Richardson PG, Gertz MA, Giralt S, Mateos MV, Leleu X, Anderson KC.

Leukemia. 2019 Apr;33(4):1058-1059. doi: 10.1038/s41375-019-0410-3.


INSIGHT MM: a large, global, prospective, non-interventional, real-world study of patients with multiple myeloma.

Costello C, Davies FE, Cook G, Vela-Ojeda J, Omel J, Rifkin RM, Berdeja J, Puig N, Usmani SZ, Weisel K, Zonder JA, Terpos E, Spencer A, Leleu X, Boccadoro M, Thompson MA, Romanus D, Stull DM, Hungria V.

Future Oncol. 2019 May;15(13):1411-1428. doi: 10.2217/fon-2019-0013. Epub 2019 Feb 28.


Early Phase I Study of a 99mTc-Labeled Anti-Programmed Death Ligand-1 (PD-L1) Single-Domain Antibody in SPECT/CT Assessment of PD-L1 Expression in Non-Small Cell Lung Cancer.

Xing Y, Chand G, Liu C, Cook GJR, O'Doherty J, Zhao L, Wong NCL, Meszaros LK, Ting HH, Zhao J.

J Nucl Med. 2019 Sep;60(9):1213-1220. doi: 10.2967/jnumed.118.224170. Epub 2019 Feb 22.


Functional characterization of BcrR: a one-component transmembrane signal transduction system for bacitracin resistance.

Darnell RL, Nakatani Y, Knottenbelt MK, Gebhard S, Cook GM.

Microbiology. 2019 Apr;165(4):475-487. doi: 10.1099/mic.0.000781. Epub 2019 Feb 19.


Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma.

Poźniak J, Nsengimana J, Laye JP, O'Shea SJ, Diaz JMS, Droop AP, Filia A, Harland M, Davies JR, Mell T, Randerson-Moor JA, Muralidhar S, Hogan SA, Freiberger SN, Levesque MP, Cook GP, Bishop DT, Newton-Bishop J.

Cancer Res. 2019 May 15;79(10):2684-2696. doi: 10.1158/0008-5472.CAN-18-2864. Epub 2019 Feb 17.


A clinical prediction model for outcome and therapy delivery in transplant-ineligible patients with myeloma (UK Myeloma Research Alliance Risk Profile): a development and validation study.

Cook G, Royle KL, Pawlyn C, Hockaday A, Shah V, Kaiser MF, Brown SR, Gregory WM, Child JA, Davies FE, Morgan GJ, Cairns DA, Jackson GH.

Lancet Haematol. 2019 Mar;6(3):e154-e166. doi: 10.1016/S2352-3026(18)30220-5. Epub 2019 Feb 6.


Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients.

Jones JR, Weinhold N, Ashby C, Walker BA, Wardell C, Pawlyn C, Rasche L, Melchor L, Cairns DA, Gregory WM, Johnson D, Begum DB, Ellis S, Sherborne AL, Cook G, Kaiser MF, Drayson MT, Owen RG, Jackson GH, Davies FE, Greaves M, Morgan GJ; NCRI Haemato-Oncology CSG.

Haematologica. 2019 Jul;104(7):1440-1450. doi: 10.3324/haematol.2018.202200. Epub 2019 Feb 7.


The impact of cytogenetics on duration of response and overall survival in patients with relapsed multiple myeloma (long-term follow-up results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial.

Cook G, Royle KL, O'Connor S, Cairns DA, Ashcroft AJ, Williams CD, Hockaday A, Cavenagh JD, Snowden JA, Ademokun D, Tholouli E, Andrews VE, Jenner M, Parrish C, Yong K, Cavet J, Hunter H, Bird JM, Pratt G, Drayson MT, Brown JM, Morris TCM; National Cancer Research Institute Haemato-oncology Clinical Studies Group.

Br J Haematol. 2019 May;185(3):450-467. doi: 10.1111/bjh.15782. Epub 2019 Feb 6.


The Antarctic psychrophiles Chlamydomonas spp. UWO241 and ICE-MDV exhibit differential restructuring of photosystem I in response to iron.

Cook G, Teufel A, Kalra I, Li W, Wang X, Priscu J, Morgan-Kiss R.

Photosynth Res. 2019 Aug;141(2):209-228. doi: 10.1007/s11120-019-00621-0. Epub 2019 Feb 7.


The structure of the catalytic domain of the ATP synthase from Mycobacterium smegmatis is a target for developing antitubercular drugs.

Zhang AT, Montgomery MG, Leslie AGW, Cook GM, Walker JE.

Proc Natl Acad Sci U S A. 2019 Jan 25. pii: 201817615. doi: 10.1073/pnas.1817615116. [Epub ahead of print]

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