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Subcutaneous Immunization of Leishmania HSP70-II Null Mutant Line Reduces the Severity of the Experimental Visceral Leishmaniasis in BALB/c Mice.

Solana JC, Ramírez L, Cook EC, Hernández-García E, Sacristán S, Martín ME, Manuel González V, Reguera RM, Balaña-Fouce R, Fresno M, Requena JM, Iborra S, Soto M.

Vaccines (Basel). 2020 Mar 23;8(1). pii: E141. doi: 10.3390/vaccines8010141.


Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.

Potus F, Pauciulo MW, Cook EK, Zhu N, Hsieh A, Welch CL, Shen Y, Tian L, Lima P, Mewburn J, D'Arsigny CL, Lutz KA, Coleman AW, Damico R, Snetsinger B, Martin AY, Hassoun PM, Nichols WC, Chung WK, Rauh MJ, Archer SL.

Circulation. 2020 Mar 20. doi: 10.1161/CIRCULATIONAHA.119.044320. [Epub ahead of print]


Pragmatic randomised evaluation of stable thoracolumbar fracture treatment outcomes (PRESTO): study protocol for a randomised controlled feasibility trial combined with a qualitative study and survey.

Cook E, Booth A, Coleman E, Scantlebury A, McDaid C, Hewitt C, Corbacho B, Rangan A, Adamson J, Ranganathan A, Khan A, Ahuja S, Turner E, May P, Hilton C, Torgerson DJ.

Pilot Feasibility Stud. 2020 Mar 13;6:38. doi: 10.1186/s40814-020-00574-5. eCollection 2020.


A maternal serum metabolite ratio predicts fetal growth restriction at term.

Sovio U, Goulding N, McBride N, Cook E, Gaccioli F, Charnock-Jones DS, Lawlor DA, Smith GCS.

Nat Med. 2020 Mar;26(3):348-353. doi: 10.1038/s41591-020-0804-9. Epub 2020 Mar 11.


Bias and stereotyping among research and clinical professionals: Perspectives on minority recruitment for oncology clinical trials.

Niranjan SJ, Martin MY, Fouad MN, Vickers SM, Wenzel JA, Cook ED, Konety BR, Durant RW.

Cancer. 2020 Mar 9. doi: 10.1002/cncr.32755. [Epub ahead of print]


Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks.

Sloand JN, Nguyen TT, Zinck SA, Cook EC, Zimudzi TJ, Showalter SA, Glick AB, Simon JC, Medina SH.

ACS Nano. 2020 Mar 11. doi: 10.1021/acsnano.9b08745. [Epub ahead of print]


Erythrodermic psoriasis secondary to systemic corticosteroids.

Heinrich M, Cook E, Roach J, Juarez RM, Payne D, Atkins R, Stetson C.

Proc (Bayl Univ Med Cent). 2019 Nov 11;33(1):113-114. doi: 10.1080/08998280.2019.1686911. eCollection 2020 Jan.


Antidepressant Target Dose Optimization and Control of Severe Asthma Exacerbations in Uninsured and Underinsured Patients with Anxiety and/or Depression.

Shoair OA, Cook EA, Shipman D, Dunn RL.

Pharmacotherapy. 2020 Feb 14. doi: 10.1002/phar.2374. [Epub ahead of print]


Fitness and productivity increase with ecotypic diversity among E. coli coevolved in a simple, constant environment.

Yang DD, Alexander A, Kinnersley M, Cook E, Caudy A, Rosebrock A, Rosenzweig F.

Appl Environ Microbiol. 2020 Feb 14. pii: AEM.00051-20. doi: 10.1128/AEM.00051-20. [Epub ahead of print]


The Use of High-Risk Criteria to Assess Mortality Risk among Unsheltered Homeless Persons.

Roncarati JS, O'Connell JJ, Hwang SW, Baggett TP, Cook EF, Krieger N, Sorensen G.

J Health Care Poor Underserved. 2020;31(1):441-454. doi: 10.1353/hpu.2020.0032.


Time Has Come for Routine Penicillin Allergy Testing in Obstetrics.

Cook E, Ramirez M, Turrentine M.

AJP Rep. 2020 Jan;10(1):e15-e19. doi: 10.1055/s-0039-3401801. Epub 2020 Feb 4.


Clonal hematopoiesis and inflammation: Partners in leukemogenesis and comorbidity.

Cook EK, Luo M, Rauh MJ.

Exp Hematol. 2020 Mar;83:85-94. doi: 10.1016/j.exphem.2020.01.011. Epub 2020 Jan 28. Review.


Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.

Satterstrom FK, Kosmicki JA, Wang J, Breen MS, De Rubeis S, An JY, Peng M, Collins R, Grove J, Klei L, Stevens C, Reichert J, Mulhern MS, Artomov M, Gerges S, Sheppard B, Xu X, Bhaduri A, Norman U, Brand H, Schwartz G, Nguyen R, Guerrero EE, Dias C; Autism Sequencing Consortium; iPSYCH-Broad Consortium, Betancur C, Cook EH, Gallagher L, Gill M, Sutcliffe JS, Thurm A, Zwick ME, Børglum AD, State MW, Cicek AE, Talkowski ME, Cutler DJ, Devlin B, Sanders SJ, Roeder K, Daly MJ, Buxbaum JD.

Cell. 2020 Feb 6;180(3):568-584.e23. doi: 10.1016/j.cell.2019.12.036. Epub 2020 Jan 23.


Familiality of behavioral flexibility and response inhibition deficits in autism spectrum disorder (ASD).

Schmitt LM, Bojanek E, White SP, Ragozzino ME, Cook EH, Sweeney JA, Mosconi MW.

Mol Autism. 2019 Dec 12;10:47. doi: 10.1186/s13229-019-0296-y. eCollection 2019.


Unexpected mitochondrial genome diversity revealed by targeted single-cell genomics of heterotrophic flagellated protists.

Wideman JG, Monier A, Rodríguez-Martínez R, Leonard G, Cook E, Poirier C, Maguire F, Milner DS, Irwin NAT, Moore K, Santoro AE, Keeling PJ, Worden AZ, Richards TA.

Nat Microbiol. 2020 Jan;5(1):154-165. doi: 10.1038/s41564-019-0605-4. Epub 2019 Nov 25.


Clinical and neurocognitive issues associated with Bosch-Boonstra-Schaaf optic atrophy syndrome: A case study.

Bojanek EK, Mosconi MW, Guter S, Betancur C, Macmillan C, Cook EH.

Am J Med Genet A. 2020 Jan;182(1):213-218. doi: 10.1002/ajmg.a.61409. Epub 2019 Nov 15.


Patient-centered Pharmacist Care in the Hemodialysis Unit: a quasi-experimental interrupted time series study.

Ismail S, Al-Subhi A, Youssif E, Ahmed M, Almalki A, Seger DL, Seger AC, Cook E.

BMC Nephrol. 2019 Nov 13;20(1):408. doi: 10.1186/s12882-019-1577-6.


Seroprevalence and associated risk factors of leptospirosis in slaughter pigs; a neglected public health risk, western Kenya.

Ngugi JN, Fèvre EM, Mgode GF, Obonyo M, Mhamphi GG, Otieno CA, Cook EAJ.

BMC Vet Res. 2019 Nov 8;15(1):403. doi: 10.1186/s12917-019-2159-3.


Short-Term Impacts of Pulse: An App-Based Teen Pregnancy Prevention Program for Black and Latinx Women.

Manlove J, Cook E, Whitfield B, Johnson M, Martínez-García G, Garrido M.

J Adolesc Health. 2020 Feb;66(2):224-232. doi: 10.1016/j.jadohealth.2019.08.017. Epub 2019 Nov 2.


PRe-hospital Evaluation of Sensitive TrOponin (PRESTO) Study: multicentre prospective diagnostic accuracy study protocol.

Alghamdi A, Cook E, Carlton E, Siriwardena A, Hann M, Thompson A, Foulkes A, Phillips J, Cooper J, Bell S, Kirby K, Rosser A, Body R.

BMJ Open. 2019 Oct 28;9(10):e032834. doi: 10.1136/bmjopen-2019-032834.


Behavioral characterization of dup15q syndrome: Toward meaningful endpoints for clinical trials.

DiStefano C, Wilson RB, Hyde C, Cook EH, Thibert RL, Reiter LT, Vogel-Farley V, Hipp J, Jeste S.

Am J Med Genet A. 2020 Jan;182(1):71-84. doi: 10.1002/ajmg.a.61385. Epub 2019 Oct 26.


The procurement of the UN sustainable development goals and the American national policy agenda of nurses.

Miyamoto S, Cook E.

Nurs Outlook. 2019 Nov - Dec;67(6):658-663. doi: 10.1016/j.outlook.2019.09.004. Epub 2019 Oct 22.


Vocabulary comprehension in adults with fragile X syndrome (FXS).

Hoffmann A, Krause SE, Wuu J, Leurgans S, Guter SJ Jr, Block SS, Salt J, Cook E Jr, Maino DM, Berry-Kravis E.

J Neurodev Disord. 2019 Oct 16;11(1):25. doi: 10.1186/s11689-019-9285-x.


Author Correction: Human placenta has no microbiome but can contain potential pathogens.

de Goffau MC, Lager S, Sovio U, Gaccioli F, Cook E, Peacock SJ, Parkhill J, Charnock-Jones DS, Smith GCS.

Nature. 2019 Oct;574(7778):E15. doi: 10.1038/s41586-019-1628-y.


Diverse conditions support near-zero growth in yeast: Implications for the study of cell lifespan.

Gulli J, Cook E, Kroll E, Rosebrock A, Caudy A, Rosenzweig F.

Microb Cell. 2019 Aug 20;6(9):397-413. doi: 10.15698/mic2019.09.690. Review.


A randomised vaccine field trial in Kenya demonstrates protection against wildebeest-associated malignant catarrhal fever in cattle.

Cook E, Russell G, Grant D, Mutisya C, Omoto L, Dobson E, Lankester F, Nene V.

Vaccine. 2019 Sep 20;37(40):5946-5953. doi: 10.1016/j.vaccine.2019.08.040. Epub 2019 Aug 28.


Comorbid and inflammatory characteristics of genetic subtypes of clonal hematopoiesis.

Cook EK, Izukawa T, Young S, Rosen G, Jamali M, Zhang L, Johnson D, Bain E, Hilland J, Ferrone CK, Buckstein J, Francis J, Momtaz B, McNaughton AJM, Liu X, Snetsinger B, Buckstein R, Rauh MJ.

Blood Adv. 2019 Aug 27;3(16):2482-2486. doi: 10.1182/bloodadvances.2018024729. No abstract available.


Human placenta has no microbiome but can contain potential pathogens.

de Goffau MC, Lager S, Sovio U, Gaccioli F, Cook E, Peacock SJ, Parkhill J, Charnock-Jones DS, Smith GCS.

Nature. 2019 Aug;572(7769):329-334. doi: 10.1038/s41586-019-1451-5. Epub 2019 Jul 31. Erratum in: Nature. 2019 Oct;574(7778):E15.


Oceanic and radiative forcing of medieval megadroughts in the American Southwest.

Steiger NJ, Smerdon JE, Cook BI, Seager R, Williams AP, Cook ER.

Sci Adv. 2019 Jul 24;5(7):eaax0087. doi: 10.1126/sciadv.aax0087. eCollection 2019 Jul.


Children's unmet palliative care needs: a scoping review of parents' perspectives.

Constantinou G, Garcia R, Cook E, Randhawa G.

BMJ Support Palliat Care. 2019 Dec;9(4):439-450. doi: 10.1136/bmjspcare-2018-001705. Epub 2019 Jul 19. Review.


Control of Taenia solium; A Case for Public and Private Sector Investment.

Thomas LF, Cook EAJ, Fèvre EM, Rushton J.

Front Vet Sci. 2019 Jun 20;6:176. doi: 10.3389/fvets.2019.00176. eCollection 2019.


College affirmative action bans and smoking and alcohol use among underrepresented minority adolescents in the United States: A difference-in-differences study.

Venkataramani AS, Cook E, O'Brien RL, Kawachi I, Jena AB, Tsai AC.

PLoS Med. 2019 Jun 18;16(6):e1002821. doi: 10.1371/journal.pmed.1002821. eCollection 2019 Jun.


One-Year Outcome Study of Anatomic Reconstruction of Lesser Metatarsophalangeal Joints.

Cook JJ, Cook EA, Hansen DD, Matthews M, Karthas T, Collier B, McKenna B, Manning E.

Foot Ankle Spec. 2019 Jun 11:1938640019846974. doi: 10.1177/1938640019846974. [Epub ahead of print]


Patient-reported care domains that enhance the experience of "being known" in an ambulatory cancer care centre.

Grover C, Mackasey E, Cook E, Nurse H, Tremblay L, Clinician N, Loiselle CG.

Can Oncol Nurs J. 2018 Jul 1;28(3):166-171. doi: 10.5737/23688076283166171. eCollection 2018 Summer.


Approches favorisant le sentiment de proximité chez le patient dans un centre de cancérologie ambulatoire.

Grover C, Mackasey E, Cook E, Tremblay L, Loiselle CG.

Can Oncol Nurs J. 2018 Jul 1;28(3):172-177. doi: 10.5737/23688076283172177. eCollection 2018 Summer. French. No abstract available.

Free PMC Article

The association between first trimester AFP to PAPP-A ratio and placentally-related adverse pregnancy outcome.

Hughes AE, Sovio U, Gaccioli F, Cook E, Charnock-Jones DS, Smith GCS.

Placenta. 2019 Jun;81:25-31. doi: 10.1016/j.placenta.2019.04.005. Epub 2019 Apr 25.


4-Hydroxyglutamate is a novel predictor of pre-eclampsia.

Sovio U, McBride N, Wood AM, Masconi KL, Cook E, Gaccioli F, Charnock-Jones DS, Lawlor DA, Smith GCS.

Int J Epidemiol. 2019 May 16. pii: dyz098. doi: 10.1093/ije/dyz098. [Epub ahead of print]


Ethnic and racial diversity in eating disorder prevention trials.

Rodgers RF, Donovan E, Cousineau TM, McGowan K, Yates K, Cook E, Lowy AS, Franko DL.

Eat Disord. 2019 Mar-Apr;27(2):168-182. doi: 10.1080/10640266.2019.1591824.


Genomic and Epidemiological Evidence of a Dominant Panton-Valentine Leucocidin-Positive Methicillin Resistant Staphylococcus aureus Lineage in Sri Lanka and Presence Among Isolates From the United Kingdom and Australia.

McTavish SM, Snow SJ, Cook EC, Pichon B, Coleman S, Coombs GW, Pang S, Arias CA, Díaz L, Boldock E, Davies S, Udukala M, Kearns AM, Siribaddana S, de Silva TI.

Front Cell Infect Microbiol. 2019 Apr 26;9:123. doi: 10.3389/fcimb.2019.00123. eCollection 2019.


Psychiatric Manifestations With Sacubitril/Valsartan: A Case Report.

Wooster J, Cook EA, Shipman D.

J Pharm Pract. 2019 Apr 16:897190019842700. doi: 10.1177/0897190019842700. [Epub ahead of print]


A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data.

Wang Q, Chen R, Cheng F, Wei Q, Ji Y, Yang H, Zhong X, Tao R, Wen Z, Sutcliffe JS, Liu C, Cook EH, Cox NJ, Li B.

Nat Neurosci. 2019 May;22(5):691-699. doi: 10.1038/s41593-019-0382-7. Epub 2019 Apr 15.


Whole Blood Serotonin Levels and Platelet 5-HT2A Binding in Autism Spectrum Disorder.

Aaron E, Montgomery A, Ren X, Guter S, Anderson G, Carneiro AMD, Jacob S, Mosconi M, Pandey GN, Cook E, Veenstra-VanderWeele J.

J Autism Dev Disord. 2019 Jun;49(6):2417-2425. doi: 10.1007/s10803-019-03989-z.


Newsletter Spring 2019: Clinician Investigator Trainee Association of Canada (CITAC).

Cook E, Ma X, Castanov V, Hutchinson N.

Clin Invest Med. 2019 Mar 23;42(1):E1-E4. doi: 10.25011/cim.v42i1.32382.


Lovastatin Treatment of a Patient with a De Novo SYNGAP1 Protein Truncating Variant.

Cook EH, Masaki JT, Guter SJ, Najjar F.

J Child Adolesc Psychopharmacol. 2019 May;29(4):321-322. doi: 10.1089/cap.2018.0159. Epub 2019 Apr 4. No abstract available.


Environment-dependent fitness gains can be driven by horizontal gene transfer of transporter-encoding genes.

Milner DS, Attah V, Cook E, Maguire F, Savory FR, Morrison M, Müller CA, Foster PG, Talbot NJ, Leonard G, Richards TA.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5613-5622. doi: 10.1073/pnas.1815994116. Epub 2019 Mar 6.


Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle.

Orono SA, Gitao GC, Mpatswenumugabo JP, Chepkwony M, Mutisya C, Okoth E, Bronsvoort BMC, Russell GC, Nene V, Cook EAJ.

BMC Vet Res. 2019 Feb 28;15(1):69. doi: 10.1186/s12917-019-1818-8.


Household socio-economic position and individual infectious disease risk in rural Kenya.

de Glanville WA, Thomas LF, Cook EAJ, Bronsvoort BMC, Wamae NC, Kariuki S, Fèvre EM.

Sci Rep. 2019 Feb 27;9(1):2972. doi: 10.1038/s41598-019-39375-z.


The emergence of Ephexin5 as a therapeutic target in Alzheimer's disease.

Cook EK, Sell GL, Schaffer TB, Margolis SS.

Expert Opin Ther Targets. 2019 Apr;23(4):263-265. doi: 10.1080/14728222.2019.1586884. Epub 2019 Mar 5. No abstract available.


CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.

Oostindie SC, van der Horst HJ, Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, VanDerMeid KR, Strumane K, Chamuleau MED, Mutis T, de Jong RN, Schuurman J, Breij ECW, Beurskens FJ, Parren PWHI, Taylor RP.

Haematologica. 2019 Sep;104(9):1841-1852. doi: 10.3324/haematol.2018.207266. Epub 2019 Feb 21.

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