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Items: 1 to 50 of 827

1.

Changes in volumetric and metabolic parameters relate to differences in exposure to sub-concussive head impacts.

Champagne AA, Coverdale NS, Germuska M, Bhogal AA, Cook DJ.

J Cereb Blood Flow Metab. 2019 Jul 15:271678X19862861. doi: 10.1177/0271678X19862861. [Epub ahead of print]

PMID:
31307284
2.

Improving End-of-Life Care in the Intensive Care Unit: Clinician's Experiences with the 3 Wishes Project.

Neville TH, Agarwal N, Swinton M, Phung P, Xu X, Kao Y, Seo J, Granone MC, Hjelmhaug K, Hainje J, Pavlish C, Clarke F, Cook DJ.

J Palliat Med. 2019 Jul 8. doi: 10.1089/jpm.2019.0135. [Epub ahead of print]

PMID:
31274366
3.

Data-informed Intervention Improves Football Technique and Reduces Head Impacts.

Champagne AA, DiStefano V, Boulanger MM, Magee B, Coverdale NS, Gallucci D, Guskiewicz K, Cook DJ.

Med Sci Sports Exerc. 2019 Jun 20. doi: 10.1249/MSS.0000000000002046. [Epub ahead of print]

PMID:
31269008
4.

Diarrhoea: interventions, consequences and epidemiology in the intensive care unit (DICE-ICU): a protocol for a prospective multicentre cohort study.

Dionne JC, Sullivan K, Mbuagbaw L, Takaoka A, Duan EH, Alhazzani W, Devlin JW, Duprey M, Moayyedi P, Armstrong D, Thabane L, Tsang JLY, Jaeschke R, Hamielec C, Karachi T, Cartin-Ceba R, Muscedere J, Alshahrani MSS, Cook DJ.

BMJ Open. 2019 Jun 27;9(6):e028237. doi: 10.1136/bmjopen-2018-028237.

5.

Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT.

Johnstone J, Heels-Ansdell D, Thabane L, Meade M, Marshall J, Lauzier F, Duan EH, Zytaruk N, Lamarche D, Surette M, Cook DJ; PROSPECT Investigators and the Canadian Critical Care Trials Group.

BMJ Open. 2019 Jun 20;9(6):e025228. doi: 10.1136/bmjopen-2018-025228.

6.

Definitions of post-coronary artery bypass grafting myocardial infarction: variations in incidence and prognostic significance.

Belley-Cote EP, Lamy A, Devereaux PJ, Kavsak P, Lamontagne F, Cook DJ, Kennedy K, Vincent J, Ou Y, Tagarakis G, Whitlock RP.

Eur J Cardiothorac Surg. 2019 Jun 10. pii: ezz161. doi: 10.1093/ejcts/ezz161. [Epub ahead of print]

PMID:
31180497
7.

The PROTROPIC feasibility study: prognostic value of elevated troponins in critical illness.

Belley-Cote EP, Whitlock RP, Ulic DV, Honarmand K, Khalifa A, McClure GR, Gibson A, Alshamsi F, D'Aragon F, Rochwerg B, Duan E, Savija N, Karachi T, Lamontagne F, Kavsak P, Cook DJ.

Can J Anaesth. 2019 Jun;66(6):648-657. doi: 10.1007/s12630-019-01375-y. Epub 2019 Apr 29.

PMID:
31037586
8.

Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients.

Kho ME, Molloy AJ, Clarke FJ, Reid JC, Herridge MS, Karachi T, Rochwerg B, Fox-Robichaud AE, Seely AJ, Mathur S, Lo V, Burns KE, Ball IM, Pellizzari JR, Tarride JE, Rudkowski JC, Koo K, Heels-Ansdell D, Cook DJ.

BMJ Open Respir Res. 2019 Feb 18;6(1):e000383. doi: 10.1136/bmjresp-2018-000383. eCollection 2019.

9.

A Device on Trial - Intermittent Pneumatic Compression in Critical Care.

Lauzier F, Douketis JD, Cook DJ.

N Engl J Med. 2019 Apr 4;380(14):1367-1368. doi: 10.1056/NEJMe1902334. No abstract available.

PMID:
30943342
10.

Frequency of Screening for Weaning From Mechanical Ventilation: Two Contemporaneous Proof-of-Principle Randomized Controlled Trials.

Burns KEA, Wong JTY, Dodek P, Cook DJ, Lamontagne F, Cohen A, Mehta S, Kho ME, Hebert PC, Aslanian P, Friedrich JO, Brochard L, Rizvi L, Hand L, Meade MO, Amaral AC, Seely AJ; Canadian Critical Care Trials Group.

Crit Care Med. 2019 Jun;47(6):817-825. doi: 10.1097/CCM.0000000000003722.

PMID:
30920411
11.

A Multidisciplinary Survey to Assess Facilitators and Barriers to Successful Organ Donation in the Intensive Care Unit.

Oczkowski SJW, Durepos P, Centofanti J, Arsenau E, Dhanani S, Cook DJ, Meade MO.

Prog Transplant. 2019 Jun;29(2):179-184. doi: 10.1177/1526924819835826. Epub 2019 Mar 21.

PMID:
30895847
12.

Resting CMRO2 fluctuations show persistent network hyper-connectivity following exposure to sub-concussive collisions.

Champagne AA, Coverdale NS, Nashed JY, Fernandez-Ruiz J, Cook DJ.

Neuroimage Clin. 2019;22:101753. doi: 10.1016/j.nicl.2019.101753. Epub 2019 Mar 12.

13.

Barriers and facilitators to adopting high value practices and de-adopting low value practices in Canadian intensive care units: a multimethod study.

Sauro K, Bagshaw SM, Niven D, Soo A, Brundin-Mather R, Parsons Leigh J, Cook DJ, Stelfox HT.

BMJ Open. 2019 Mar 15;9(3):e024159. doi: 10.1136/bmjopen-2018-024159.

14.

A mixed-methods study of organ donation in the intensive care unit: 22 actionable practices to improve organ donation.

Oczkowski SJW, Arnold E, Centofanti J, Durepos P, Sarti A, Arseneau E, Dhanani S, Cook DJ, Meade MO.

Can J Anaesth. 2019 Jun;66(6):686-695. doi: 10.1007/s12630-019-01332-9. Epub 2019 Feb 26.

PMID:
30809778
15.

A multicentre controlled pre-post trial of an implementation science intervention to improve venous thromboembolism prophylaxis in critically ill patients.

Stelfox HT, Brundin-Mather R, Soo A, Parsons Leigh J, Niven DJ, Fiest KM, Doig CJ, Zuege DJ, Kushner B, Clement F, Straus SE, Cook DJ, Bagshaw SM, Sauro KM.

Intensive Care Med. 2019 Feb;45(2):211-222. doi: 10.1007/s00134-019-05532-1. Epub 2019 Feb 1.

PMID:
30707246
16.

Feasibility, Reliability, Responsiveness, and Validity of the Patient-Reported Functional Scale for the Intensive Care Unit: A Pilot Study.

Reid JC, Clarke F, Cook DJ, Molloy A, Rudkowski JC, Stratford P, Kho ME.

J Intensive Care Med. 2019 Jan 22:885066618824534. doi: 10.1177/0885066618824534. [Epub ahead of print]

PMID:
30669936
17.

Benchmarks of Duration and Magnitude of Opioid Consumption After Total Hip and Knee Arthroplasty: A Database Analysis of 69,368 Patients.

Cook DJ, Kaskovich SW, Pirkle SC, Mica MAC, Shi LL, Lee MJ.

J Arthroplasty. 2019 Apr;34(4):638-644.e1. doi: 10.1016/j.arth.2018.12.023. Epub 2018 Dec 24.

PMID:
30642706
18.

Improving the adoption of optimal venous thromboembolism prophylaxis in critically ill patients: A process evaluation of a complex quality improvement initiative.

Sauro KM, Brundin-Mather R, Parsons Leigh J, Niven DJ, Kushner B, Soo A, Cook DJ, Straus S, Doig CJ, Bagshaw S, Stelfox HT.

J Crit Care. 2019 Apr;50:111-117. doi: 10.1016/j.jcrc.2018.11.023. Epub 2018 Nov 29.

PMID:
30529419
19.

Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study.

Lamarche D, Johnstone J, Zytaruk N, Clarke F, Hand L, Loukov D, Szamosi JC, Rossi L, Schenck LP, Verschoor CP, McDonald E, Meade MO, Marshall JC, Bowdish DME, Karachi T, Heels-Ansdell D, Cook DJ, Surette MG; PROSPECT Investigators; Canadian Critical Care Trials Group; Canadian Critical Care Translational Biology Group.

Respir Res. 2018 Dec 7;19(1):245. doi: 10.1186/s12931-018-0950-5.

20.

CNB-001, a pleiotropic drug is efficacious in embolized agyrencephalic New Zealand white rabbits and ischemic gyrencephalic cynomolgus monkeys.

Lapchak PA, Boitano PD, Bombien R, Cook DJ, Doyan S, Lara JM, Schubert DR.

Exp Neurol. 2019 Mar;313:98-108. doi: 10.1016/j.expneurol.2018.11.010. Epub 2018 Dec 4.

PMID:
30521790
21.

Stroke Longitudinal Volumetric Measures Correlate with the Behavioral Score in Non-Human Primates.

Ramirez-Garcia G, Harrison KA, Fernandez-Ruiz J, Nashed JY, Cook DJ.

Neuroscience. 2019 Jan 15;397:41-55. doi: 10.1016/j.neuroscience.2018.11.026. Epub 2018 Nov 24.

PMID:
30481566
22.

Porous titanium-coated polyetheretherketone implants exhibit an improved bone-implant interface: an in vitro and in vivo biochemical, biomechanical, and histological study.

Cheng BC, Koduri S, Wing CA, Woolery N, Cook DJ, Spiro RC.

Med Devices (Auckl). 2018 Oct 29;11:391-402. doi: 10.2147/MDER.S180482. eCollection 2018.

23.

Cages in ACDF are Associated With a Higher Nonunion Rate Than Allograft: A Stratified Comparative Analysis of 6130 Patients.

Pirkle S, Kaskovich S, Cook DJ, Ho A, Shi LL, Lee MJ.

Spine (Phila Pa 1976). 2019 Mar 15;44(6):384-388. doi: 10.1097/BRS.0000000000002854.

PMID:
30180149
24.

FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial.

McIntyre L, Taljaard M, McArdle T, Fox-Robichaud A, English SW, Martin C, Marshall J, Menon K, Muscedere J, Cook DJ, Weijer C, Saginur R, Maybee A, Iyengar A, Forster A, Graham ID, Hawken S, McCartney C, Seely AJ, Stiell IG, Thavorn K, Fergusson DA.

BMJ Open. 2018 Aug 23;8(8):e022780. doi: 10.1136/bmjopen-2018-022780.

25.

Iterative Design of Visual Analytics for a Clinician-in-the-Loop Smart Home.

Ghods A, Caffrey K, Lin B, Fraga K, Fritz R, Schmitter-Edgecombe M, Hundhausen C, Cook DJ.

IEEE J Biomed Health Inform. 2019 Jul;23(4):1742-1748. doi: 10.1109/JBHI.2018.2864287. Epub 2018 Aug 8.

26.

Advancing Randomized Controlled Trials in Pediatric Critical Care: The Perspectives of Trialists.

Duffett M, Swinton M, Brouwers M, Meade M, Cook DJ.

Pediatr Crit Care Med. 2018 Nov;19(11):e595-e602. doi: 10.1097/PCC.0000000000001696.

PMID:
30074981
27.

Technology-Enabled Assessment of Functional Health.

Cook DJ, Schmitter-Edgecombe M, Jonsson L, Morant AV.

IEEE Rev Biomed Eng. 2019;12:319-332. doi: 10.1109/RBME.2018.2851500. Epub 2018 Jun 28. Review.

PMID:
29994684
28.

Smart Home-Based Prediction of Multidomain Symptoms Related to Alzheimer's Disease.

Alberdi A, Weakley A, Schmitter-Edgecombe M, Cook DJ, Aztiria A, Basarab A, Barrenechea M.

IEEE J Biomed Health Inform. 2018 Nov;22(6):1720-1731. doi: 10.1109/JBHI.2018.2798062. Epub 2018 Jan 25.

PMID:
29994359
29.

The Deferred Consent Model in a Prospective Observational Study Evaluating Myocardial Injury in the Intensive Care Unit.

Honarmand K, Belley-Cote EP, Ulic D, Khalifa A, Gibson A, McClure G, Savija N, Alshamsi F, D'Aragon F, Rochwerg B, Duan EH, Karachi T, Lamontagne F, Devereaux PJ, Whitlock RP, Cook DJ.

J Intensive Care Med. 2018 Aug;33(8):475-480. doi: 10.1177/0885066616680772. Epub 2016 Dec 16.

PMID:
29991343
30.

Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial.

Pai M, Adhikari NKJ, Ostermann M, Heels-Ansdell D, Douketis JD, Skrobik Y, Qushmaq I, Meade M, Guyatt G, Geerts W, Walsh MW, Crowther MA, Friedrich JO, Burry L, Bellomo R, Brandão da Silva N, Costa Filho R, Cox MJ, Alves Silva S, Cook DJ; PROTECT (Prophylaxis for Thromboembolism in Critical Care Trial) Investigators.

PLoS One. 2018 Jun 1;13(6):e0198285. doi: 10.1371/journal.pone.0198285. eCollection 2018.

31.

Using Smart City Technology to Make Healthcare Smarter.

Cook DJ, Duncan G, Sprint G, Fritz R.

Proc IEEE Inst Electr Electron Eng. 2018 Apr;106(4):708-722. doi: 10.1109/JPROC.2017.2787688. Epub 2018 Jan 23.

32.

Implementing Wearable Sensors for Continuous Assessment of Daytime Heart Rate Response in Inpatient Rehabilitation.

Weeks DL, Sprint GL, Stilwill V, Meisen-Vehrs AL, Cook DJ.

Telemed J E Health. 2018 Apr 2. doi: 10.1089/tmj.2017.0306. [Epub ahead of print]

PMID:
29608421
33.

Assessing frailty in the intensive care unit: A reliability and validity study.

Shears M, Takaoka A, Rochwerg B, Bagshaw SM, Johnstone J, Holding A, Tharmalingam S, Millen T, Clarke F, Rockwood K, Li G, Thabane L, Muscedere J, Stelfox HT, Cook DJ; Canadian Critical Care Trials Group.

J Crit Care. 2018 Jun;45:197-203. doi: 10.1016/j.jcrc.2018.02.004. Epub 2018 Feb 8.

PMID:
29574340
34.

Automatic assessment of functional health decline in older adults based on smart home data.

Alberdi Aramendi A, Weakley A, Aztiria Goenaga A, Schmitter-Edgecombe M, Cook DJ.

J Biomed Inform. 2018 May;81:119-130. doi: 10.1016/j.jbi.2018.03.009. Epub 2018 Mar 15.

35.

International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation.

Burns KEA, Raptis S, Nisenbaum R, Rizvi L, Jones A, Bakshi J, Tan W, Meret A, Cook DJ, Lellouche F, Epstein SK, Gattas D, Kapadia FN, Villar J, Brochard L, Lessard MR, Meade MO.

Ann Am Thorac Soc. 2018 Apr;15(4):494-502. doi: 10.1513/AnnalsATS.201705-410OC. Erratum in: Ann Am Thorac Soc. 2018 Jul;15(7):894.

PMID:
29509509
36.

Learning Activity Predictors from Sensor Data: Algorithms, Evaluation, and Applications.

Minor B, Doppa JR, Cook DJ.

IEEE Trans Knowl Data Eng. 2017 Dec 1;29(12):2744-2757. doi: 10.1109/TKDE.2017.2750669. Epub 2017 Sep 11.

37.

7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial.

Daneman N, Rishu AH, Pinto R, Aslanian P, Bagshaw SM, Carignan A, Charbonney E, Coburn B, Cook DJ, Detsky ME, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Sligl W, Stelfox HT, Wilcox ME, Fowler RA; Canadian Critical Care Trials Group.

Trials. 2018 Feb 17;19(1):111. doi: 10.1186/s13063-018-2474-1.

38.

Functionalized metal-organic framework nanocomposites for dispersive solid phase extraction and enantioselective capture of chiral drug intermediates.

Ma X, Zhou X, Yu A, Zhao W, Zhang W, Zhang S, Wei L, Cook DJ, Roy A.

J Chromatogr A. 2018 Feb 16;1537:1-9. doi: 10.1016/j.chroma.2017.12.067. Epub 2018 Jan 6.

PMID:
29336807
39.

Organ donation in the ICU: A document analysis of institutional policies, protocols, and order sets.

Oczkowski SJW, Centofanti JE, Durepos P, Arseneau E, Kelecevic J, Cook DJ, Meade MO.

Intensive Crit Care Nurs. 2018 Apr;45:58-65. doi: 10.1016/j.iccn.2017.12.005. Epub 2018 Jan 10.

PMID:
29331633
40.

Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.

Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P.

Intensive Care Med. 2018 Jan;44(1):12-21. doi: 10.1007/s00134-017-5016-5. Epub 2017 Dec 19.

PMID:
29260272
41.

A novel perspective to calibrate temporal delays in cerebrovascular reactivity using hypercapnic and hyperoxic respiratory challenges.

Champagne AA, Bhogal AA, Coverdale NS, Mark CI, Cook DJ.

Neuroimage. 2019 Feb 15;187:154-165. doi: 10.1016/j.neuroimage.2017.11.044. Epub 2017 Dec 5.

PMID:
29217405
42.

Recovery after critical illness: putting the puzzle together-a consensus of 29.

Azoulay E, Vincent JL, Angus DC, Arabi YM, Brochard L, Brett SJ, Citerio G, Cook DJ, Curtis JR, Dos Santos CC, Ely EW, Hall J, Halpern SD, Hart N, Hopkins RO, Iwashyna TJ, Jaber S, Latronico N, Mehta S, Needham DM, Nelson J, Puntillo K, Quintel M, Rowan K, Rubenfeld G, Van den Berghe G, Van der Hoeven J, Wunsch H, Herridge M.

Crit Care. 2017 Dec 5;21(1):296. doi: 10.1186/s13054-017-1887-7. Review.

43.

Complete Acid-Based Hydrolysis Assay for Carbohydrate Quantification in Seaweed: A Species-Specific Optimized Approach.

Kostas ET, Wilkinson SJ, White DA, Cook DJ.

Methods Mol Biol. 2017 Nov 14. doi: 10.1007/7651_2017_105. [Epub ahead of print]

PMID:
29134619
44.

Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.

Graham MM, Sessler DI, Parlow JL, Biccard BM, Guyatt G, Leslie K, Chan MTV, Meyhoff CS, Xavier D, Sigamani A, Kumar PA, Mrkobrada M, Cook DJ, Tandon V, Alvarez-Garcia J, Villar JC, Painter TW, Landoni G, Fleischmann E, Lamy A, Whitlock R, Le Manach Y, Aphang-Lam M, Cata JP, Gao P, Terblanche NCS, Ramana PV, Jamieson KA, Bessissow A, Mendoza GR, Ramirez S, Diemunsch PA, Yusuf S, Devereaux PJ.

Ann Intern Med. 2018 Feb 20;168(4):237-244. doi: 10.7326/M17-2341. Epub 2017 Nov 14.

PMID:
29132159
45.

2009-2010 Influenza A(H1N1)-related critical illness among Aboriginal and non-Aboriginal Canadians.

Jung JJ, Pinto R, Zarychanski R, Cook DJ, Jouvet P, Marshall JC, Kumar A, Long J, Rodin R, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative.

PLoS One. 2017 Oct 19;12(10):e0184013. doi: 10.1371/journal.pone.0184013. eCollection 2017.

46.

Collegial Activity Learning between Heterogeneous Sensors.

Feuz KD, Cook DJ.

Knowl Inf Syst. 2017 Nov;53(2):337-364. doi: 10.1007/s10115-017-1043-3. Epub 2017 Mar 27.

47.

Smart Secure Homes: A Survey of Smart Home Technologies that Sense, Assess, and Respond to Security Threats.

Dahmen J, Cook DJ, Wang X, Honglei W.

J Reliab Intell Environ. 2017 Aug;3(2):83-98. doi: 10.1007/s40860-017-0035-0. Epub 2017 Feb 15.

48.

Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors.

D'Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chassé M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program.

BMJ Open. 2017 Sep 28;7(9):e018858. doi: 10.1136/bmjopen-2017-018858.

49.

Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study.

Duan EH, Adhikari NKJ, D'Aragon F, Cook DJ, Mehta S, Alhazzani W, Goligher E, Charbonney E, Arabi YM, Karachi T, Turgeon AF, Hand L, Zhou Q, Austin P, Friedrich J, Lamontagne F, Lauzier F, Patel R, Muscedere J, Hall R, Aslanian P, Piraino T, Albert M, Bagshaw SM, Jacka M, Wood G, Henderson W, Dorscheid D, Ferguson ND, Meade MO; Canadian Critical Care Trials Group.

Ann Am Thorac Soc. 2017 Dec;14(12):1818-1826. doi: 10.1513/AnnalsATS.201612-1042OC.

PMID:
28910146
50.

Need for a Randomized Controlled Trial of Stress Ulcer Prophylaxis in Critically Ill Children: A Canadian Survey.

Duffett M, Choong K, Foster J, Gilfoyle E, Lacroix J, Cook DJ.

Can J Hosp Pharm. 2017 Jul-Aug;70(4):288-293. Epub 2017 Aug 31.

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