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Heterozygous STUB1 missense variants cause ataxia, cognitive decline, and STUB1 mislocalization.

Chen DH, Latimer C, Yagi M, Ndugga-Kabuye MK, Heigham E, Jayadev S, Meabon JS, Gomez CM, Keene CD, Cook DG, Raskind WH, Bird TD.

Neurol Genet. 2020 Feb 10;6(2):1-13. doi: 10.1212/NXG.0000000000000397. eCollection 2020 Apr.


Development of a structured clinical pharmacology review for specialist support for management of complex polypharmacy in primary care.

Threapleton CJD, Kimpton JE, Carey IM, DeWilde S, Cook DG, Harris T, Baker EH.

Br J Clin Pharmacol. 2020 Feb 14. doi: 10.1111/bcp.14243. [Epub ahead of print]


The effect of moving to East Village, the former London 2012 Olympic and Paralympic Games Athletes' Village, on mode of travel (ENABLE London study, a natural experiment).

Limb ES, Procter DS, Cooper AR, Page AS, Nightingale CM, Ram B, Shankar A, Clary C, Lewis D, Cummins S, Ellaway A, Giles-Corti B, Whincup PH, Rudnicka AR, Cook DG, Owen CG.

Int J Behav Nutr Phys Act. 2020 Feb 10;17(1):15. doi: 10.1186/s12966-020-0916-0.


Alterations in Plasma microRNA and Protein Levels in War Veterans with Chronic Mild Traumatic Brain Injury.

Ghai V, Fallen S, Baxter D, Scherler K, Kim TK, Zhou Y, Meabon JS, Logsdon AF, Banks WA, Schindler AG, Cook DG, Peskind ER, Lee I, Wang K.

J Neurotrauma. 2020 Mar 11. doi: 10.1089/neu.2019.6826. [Epub ahead of print]


The effect of temperature and meal size on the aerobic scope and specific dynamic action of two temperate New Zealand finfish Chrysophrys auratus and Aldrichetta forsteri.

Flikac T, Cook DG, Davison W.

J Comp Physiol B. 2020 Mar;190(2):169-183. doi: 10.1007/s00360-020-01258-5. Epub 2020 Jan 29.


Reducing weight and increasing physical activity in people at high risk of cardiovascular disease: a randomised controlled trial comparing the effectiveness of enhanced motivational interviewing intervention with usual care.

Ismail K, Bayley A, Twist K, Stewart K, Ridge K, Britneff E, Greenough A, Ashworth M, Rundle J, Cook DG, Whincup P, Treasure J, McCrone P, Winkley K, Stahl D.

Heart. 2020 Mar;106(6):447-454. doi: 10.1136/heartjnl-2019-315656. Epub 2019 Dec 12.


Variability in Glycated Hemoglobin and Risk of Poor Outcomes Among People With Type 2 Diabetes in a Large Primary Care Cohort Study.

Critchley JA, Carey IM, Harris T, DeWilde S, Cook DG.

Diabetes Care. 2019 Dec;42(12):2237-2246. doi: 10.2337/dc19-0848. Epub 2019 Oct 3.


Equity-Specific Effects of Interventions to Promote Physical Activity among Middle-Aged and Older Adults: Development of a Collaborative Equity-Specific Re-Analysis Strategy.

Czwikla G, Boen F, Cook DG, de Jong J, Harris T, Hilz LK, Iliffe S, Morris R, Muellmann S, Peels DA, Pischke CR, Schüz B, Stevens M, van Lenthe FJ, Vanderlinden J, Bolte G.

Int J Environ Res Public Health. 2019 Sep 1;16(17). pii: E3195. doi: 10.3390/ijerph16173195.


Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing.

Kimpton JE, Carey IM, Threapleton CJD, Robinson A, Harris T, Cook DG, DeWilde S, Baker EH.

Br J Clin Pharmacol. 2019 Dec;85(12):2734-2746. doi: 10.1111/bcp.14100. Epub 2019 Dec 13.


The effect of moving to East Village, the former London 2012 Olympic and Paralympic Games Athletes' Village, on physical activity and adiposity (ENABLE London): a cohort study.

Nightingale CM, Limb ES, Ram B, Shankar A, Clary C, Lewis D, Cummins S, Procter D, Cooper AR, Page AS, Ellaway A, Giles-Corti B, Whincup PH, Rudnicka AR, Cook DG, Owen CG.

Lancet Public Health. 2019 Aug;4(8):e421-e430. doi: 10.1016/S2468-2667(19)30133-1. Epub 2019 Jul 22.


Development and validation of a prediction model for fat mass in children and adolescents: meta-analysis using individual participant data.

Hudda MT, Fewtrell MS, Haroun D, Lum S, Williams JE, Wells JCK, Riley RD, Owen CG, Cook DG, Rudnicka AR, Whincup PH, Nightingale CM.

BMJ. 2019 Jul 24;366:l4293. doi: 10.1136/bmj.l4293.


Effect of pedometer-based walking interventions on long-term health outcomes: Prospective 4-year follow-up of two randomised controlled trials using routine primary care data.

Harris T, Limb ES, Hosking F, Carey I, DeWilde S, Furness C, Wahlich C, Ahmad S, Kerry S, Whincup P, Victor C, Ussher M, Iliffe S, Ekelund U, Fox-Rushby J, Ibison J, Cook DG.

PLoS Med. 2019 Jun 25;16(6):e1002836. doi: 10.1371/journal.pmed.1002836. eCollection 2019 Jun.


A candidate gene approach identifies variants in SLC45A2 that explain dilute phenotypes, pearl and sunshine, in compound heterozygote horses.

Holl HM, Pflug KM, Yates KM, Hoefs-Martin K, Shepard C, Cook DG, Lafayette C, Brooks SA.

Anim Genet. 2019 Jun;50(3):271-274. doi: 10.1111/age.12790. Epub 2019 Apr 21.


Measuring change in trials of physical activity interventions: a comparison of self-report questionnaire and accelerometry within the PACE-UP trial.

Limb ES, Ahmad S, Cook DG, Kerry SM, Ekelund U, Whincup PH, Victor CR, Iliffe S, Ussher M, Fox-Rushby J, Furness C, Ibison J, DeWilde S, Harris T.

Int J Behav Nutr Phys Act. 2019 Jan 22;16(1):10. doi: 10.1186/s12966-018-0762-5.


Paclitaxel Reduces Brain Injury from Repeated Head Trauma in Mice.

Cross DJ, Meabon JS, Cline MM, Richards TL, Stump AJ, Cross CG, Minoshima S, Banks WA, Cook DG.

J Alzheimers Dis. 2019;67(3):859-874. doi: 10.3233/JAD-180871.


Exploring the use of adjusted body mass index thresholds based on equivalent insulin resistance for defining overweight and obesity in UK South Asian children.

Hudda MT, Donin AS, Owen CG, Rudnicka AR, Sattar N, Cook DG, Whincup PH, Nightingale CM.

Int J Obes (Lond). 2019 Jul;43(7):1440-1443. doi: 10.1038/s41366-018-0279-7. Epub 2018 Dec 13.


Effect of blast-related mTBI on the working memory system: a resting state fMRI study.

Pagulayan KF, Petrie EC, Cook DG, Hendrickson RC, Rau H, Reilly M, Mayer C, Meabon JS, Raskind MA, Peskind ER, Kleinhans N.

Brain Imaging Behav. 2018 Dec 5. doi: 10.1007/s11682-018-9987-9. [Epub ahead of print]


Short-term and long-term cost-effectiveness of a pedometer-based exercise intervention in primary care: a within-trial analysis and beyond-trial modelling.

Anokye N, Fox-Rushby J, Sanghera S, Cook DG, Limb E, Furness C, Kerry SM, Victor CR, Iliffe S, Ussher M, Whincup PH, Ekelund U, deWilde S, Harris T.

BMJ Open. 2018 Oct 17;8(10):e021978. doi: 10.1136/bmjopen-2018-021978.


An open-source tool to identify active travel from hip-worn accelerometer, GPS and GIS data.

Procter DS, Page AS, Cooper AR, Nightingale CM, Ram B, Rudnicka AR, Whincup PH, Clary C, Lewis D, Cummins S, Ellaway A, Giles-Corti B, Cook DG, Owen CG.

Int J Behav Nutr Phys Act. 2018 Sep 21;15(1):91. doi: 10.1186/s12966-018-0724-y.


Are noise and air pollution related to the incidence of dementia? A cohort study in London, England.

Carey IM, Anderson HR, Atkinson RW, Beevers SD, Cook DG, Strachan DP, Dajnak D, Gulliver J, Kelly FJ.

BMJ Open. 2018 Sep 11;8(9):e022404. doi: 10.1136/bmjopen-2018-022404.


Response bias to a randomised controlled trial of a lifestyle intervention in people at high risk of cardiovascular disease: a cross-sectional analysis.

Bayley A, Stahl D, Ashworth M, Cook DG, Whincup PH, Treasure J, Greenough A, Ridge K, Winkley K, Ismail K.

BMC Public Health. 2018 Sep 4;18(1):1092. doi: 10.1186/s12889-018-5939-y.


Housing, neighbourhood and sociodemographic associations with adult levels of physical activity and adiposity: baseline findings from the ENABLE London study.

Nightingale CM, Rudnicka AR, Ram B, Shankar A, Limb ES, Procter D, Cooper AR, Page AS, Ellaway A, Giles-Corti B, Clary C, Lewis D, Cummins S, Whincup PH, Cook DG, Owen CG.

BMJ Open. 2018 Aug 17;8(8):e021257. doi: 10.1136/bmjopen-2017-021257.


Glycemic Control and Risk of Infections Among People With Type 1 or Type 2 Diabetes in a Large Primary Care Cohort Study.

Critchley JA, Carey IM, Harris T, DeWilde S, Hosking FJ, Cook DG.

Diabetes Care. 2018 Oct;41(10):2127-2135. doi: 10.2337/dc18-0287. Epub 2018 Aug 13.


Blast exposure elicits blood-brain barrier disruption and repair mediated by tight junction integrity and nitric oxide dependent processes.

Logsdon AF, Meabon JS, Cline MM, Bullock KM, Raskind MA, Peskind ER, Banks WA, Cook DG.

Sci Rep. 2018 Jul 27;8(1):11344. doi: 10.1038/s41598-018-29341-6.


Association between depressive symptoms and objectively measured daily step count in individuals at high risk of cardiovascular disease in South London, UK: a cross-sectional study.

Ludwig VM, Bayley A, Cook DG, Stahl D, Treasure JL, Asthworth M, Greenough A, Winkley K, Bornstein SR, Ismail K.

BMJ Open. 2018 Apr 12;8(4):e020942. doi: 10.1136/bmjopen-2017-020942.


Effects of group size on school structure and behaviour in yellow-eyed mullet Aldrichetta forsteri.

Middlemiss KL, Cook DG, Jerrett AR, Davison W.

J Fish Biol. 2018 May;92(5):1255-1272. doi: 10.1111/jfb.13581. Epub 2018 Mar 12.


Physical activity levels in adults and older adults 3-4 years after pedometer-based walking interventions: Long-term follow-up of participants from two randomised controlled trials in UK primary care.

Harris T, Kerry SM, Limb ES, Furness C, Wahlich C, Victor CR, Iliffe S, Whincup PH, Ussher M, Ekelund U, Fox-Rushby J, Ibison J, DeWilde S, McKay C, Cook DG.

PLoS Med. 2018 Mar 9;15(3):e1002526. doi: 10.1371/journal.pmed.1002526. eCollection 2018 Mar.


The contribution of physical fitness to individual and ethnic differences in risk markers for type 2 diabetes in children: The Child Heart and Health Study in England (CHASE).

Nightingale CM, Rudnicka AR, Kerry-Barnard SR, Donin AS, Brage S, Westgate KL, Ekelund U, Cook DG, Owen CG, Whincup PH.

Pediatr Diabetes. 2018 Jun;19(4):603-610. doi: 10.1111/pedi.12637. Epub 2018 Feb 7.


Interpreting population reach of a large, successful physical activity trial delivered through primary care.

Kerry SM, Morgan KE, Limb E, Cook DG, Furness C, Carey I, DeWilde S, Victor CR, Iliffe S, Whincup P, Ussher M, Ekelund U, Fox-Rushby J, Ibison J, Harris T.

BMC Public Health. 2018 Jan 23;18(1):170. doi: 10.1186/s12889-018-5034-4.


Relating process evaluation measures to complex intervention outcomes: findings from the PACE-UP primary care pedometer-based walking trial.

Furness C, Howard E, Limb E, Cook DG, Kerry S, Wahlich C, Victor C, Ekelund U, Iliffe S, Ussher M, Whincup P, Fox-Rushby J, Ibison J, DeWilde S, Harris T.

Trials. 2018 Jan 22;19(1):58. doi: 10.1186/s13063-017-2428-z.


Risk of Infection in Type 1 and Type 2 Diabetes Compared With the General Population: A Matched Cohort Study.

Carey IM, Critchley JA, DeWilde S, Harris T, Hosking FJ, Cook DG.

Diabetes Care. 2018 Mar;41(3):513-521. doi: 10.2337/dc17-2131. Epub 2018 Jan 12.


Retrospective and Prospective Memory Among OEF/OIF/OND Veterans With a Self-Reported History of Blast-Related mTBI.

Pagulayan KF, Rau H, Madathil R, Werhane M, Millard SP, Petrie EC, Parmenter B, Peterson S, Sorg S, Hendrickson R, Mayer C, Meabon JS, Huber BR, Raskind M, Cook DG, Peskind ER.

J Int Neuropsychol Soc. 2018 Apr;24(4):324-334. doi: 10.1017/S1355617717001217. Epub 2017 Dec 29.


Reassessing Ethnic Differences in Mean BMI and Changes Between 2007 and 2013 in English Children.

Hudda MT, Nightingale CM, Donin AS, Owen CG, Rudnicka AR, Wells JCK, Rutter H, Cook DG, Whincup PH.

Obesity (Silver Spring). 2018 Feb;26(2):412-419. doi: 10.1002/oby.22091. Epub 2017 Dec 17.


Takeaway meal consumption and risk markers for coronary heart disease, type 2 diabetes and obesity in children aged 9-10 years: a cross-sectional study.

Donin AS, Nightingale CM, Owen CG, Rudnicka AR, Cook DG, Whincup PH.

Arch Dis Child. 2018 May;103(5):431-436. doi: 10.1136/archdischild-2017-312981. Epub 2017 Dec 3.


Patterns of childhood body mass index (BMI), overweight and obesity in South Asian and black participants in the English National child measurement programme: effect of applying BMI adjustments standardising for ethnic differences in BMI-body fatness associations.

Hudda MT, Nightingale CM, Donin AS, Owen CG, Rudnicka AR, Wells JCK, Rutter H, Cook DG, Whincup PH.

Int J Obes (Lond). 2018 Apr;42(4):662-670. doi: 10.1038/ijo.2017.272. Epub 2017 Nov 2.


Fatigue - but not mTBI history, PTSD, or sleep quality - directly contributes to reduced prospective memory performance in Iraq and Afghanistan era Veterans.

Rau HK, Hendrickson RC, Roggenkamp HC, Peterson S, Parmenter B, Cook DG, Peskind E, Pagulayan KF.

Clin Neuropsychol. 2018 Aug - Oct;32(7):1319-1336. doi: 10.1080/13854046.2017.1381277. Epub 2017 Oct 13.


Comparisons of depression, anxiety, well-being, and perceptions of the built environment amongst adults seeking social, intermediate and market-rent accommodation in the former London Olympic Athletes' Village.

Ram B, Shankar A, Nightingale CM, Giles-Corti B, Ellaway A, Cooper AR, Page A, Cummins S, Lewis D, Whincup PH, Cook DG, Rudnicka AR, Owen CG.

Health Place. 2017 Nov;48:31-39. doi: 10.1016/j.healthplace.2017.09.001. Epub 2017 Sep 23.


ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.

Cao J, Gaamouch FE, Meabon JS, Meeker KD, Zhu L, Zhong MB, Bendik J, Elder G, Jing P, Xia J, Luo W, Cook DG, Cai D.

Sci Rep. 2017 Sep 12;7(1):11372. doi: 10.1038/s41598-017-11654-7.


Preventable Emergency Hospital Admissions Among Adults With Intellectual Disability in England.

Hosking FJ, Carey IM, DeWilde S, Harris T, Beighton C, Cook DG.

Ann Fam Med. 2017 Sep;15(5):462-470. doi: 10.1370/afm.2104. Erratum in: Ann Fam Med. 2017 Nov;15(6):503.


'I'm sure we made it a better study…': Experiences of adults with intellectual disabilities and parent carers of patient and public involvement in a health research study.

Beighton C, Victor C, Carey IM, Hosking F, DeWilde S, Cook DG, Manners P, Harris T.

J Intellect Disabil. 2019 Mar;23(1):78-96. doi: 10.1177/1744629517723485. Epub 2017 Aug 16.


Sleep Duration and Risk of Type 2 Diabetes.

Rudnicka AR, Nightingale CM, Donin AS, Sattar N, Cook DG, Whincup PH, Owen CG.

Pediatrics. 2017 Sep;140(3). pii: e20170338. doi: 10.1542/peds.2017-0338. Epub 2017 Aug 15.


Blast-related disinhibition and risk seeking in mice and combat Veterans: Potential role for dysfunctional phasic dopamine release.

Schindler AG, Meabon JS, Pagulayan KF, Hendrickson RC, Meeker KD, Cline M, Li G, Sikkema C, Wilkinson CW, Perl DP, Raskind MR, Peskind ER, Clark JJ, Cook DG.

Neurobiol Dis. 2017 Oct;106:23-34. doi: 10.1016/j.nbd.2017.06.004. Epub 2017 Jun 12.


Morphology and hydro-sensory role of superficial neuromasts in schooling behaviour of yellow-eyed mullet (Aldrichetta forsteri).

Middlemiss KL, Cook DG, Jerrett AR, Davison W.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2017 Oct;203(10):807-817. doi: 10.1007/s00359-017-1192-6. Epub 2017 Jun 9.


Body mass index adjustments to increase the validity of body fatness assessment in UK Black African and South Asian children.

Hudda MT, Nightingale CM, Donin AS, Fewtrell MS, Haroun D, Lum S, Williams JE, Owen CG, Rudnicka AR, Wells JCK, Cook DG, Whincup PH.

Int J Obes (Lond). 2017 Jul;41(7):1048-1055. doi: 10.1038/ijo.2017.75. Epub 2017 Mar 22.


Screen time is associated with adiposity and insulin resistance in children.

Nightingale CM, Rudnicka AR, Donin AS, Sattar N, Cook DG, Whincup PH, Owen CG.

Arch Dis Child. 2017 Jul;102(7):612-616. doi: 10.1136/archdischild-2016-312016. Epub 2017 Mar 13.


Effect of a Primary Care Walking Intervention with and without Nurse Support on Physical Activity Levels in 45- to 75-Year-Olds: The Pedometer And Consultation Evaluation (PACE-UP) Cluster Randomised Clinical Trial.

Harris T, Kerry SM, Limb ES, Victor CR, Iliffe S, Ussher M, Whincup PH, Ekelund U, Fox-Rushby J, Furness C, Anokye N, Ibison J, DeWilde S, David L, Howard E, Dale R, Smith J, Cook DG.

PLoS Med. 2017 Jan 3;14(1):e1002210. doi: 10.1371/journal.pmed.1002210. eCollection 2017 Jan.


Novel application of a Radial Water Tread maze can distinguish cognitive deficits in mice with traumatic brain injury.

Cline MM, Yumul JC, Hysa L, Murra D, Garwin GG, Cook DG, Ladiges WC, Minoshima S, Cross DJ.

Brain Res. 2017 Feb 15;1657:140-147. doi: 10.1016/j.brainres.2016.11.027. Epub 2016 Dec 5.


Cohort profile: Examining Neighbourhood Activities in Built Living Environments in London: the ENABLE London-Olympic Park cohort.

Ram B, Nightingale CM, Hudda MT, Kapetanakis VV, Ellaway A, Cooper AR, Page A, Lewis D, Cummins S, Giles-Corti B, Whincup PH, Cook DG, Rudnicka AR, Owen CG.

BMJ Open. 2016 Oct 28;6(10):e012643. doi: 10.1136/bmjopen-2016-012643.


What factors support older people to increase their physical activity levels? An exploratory analysis of the experiences of PACE-Lift trial participants.

Victor CR, Rogers A, Woodcock A, Beighton C, Cook DG, Kerry SM, Iliffe S, Whincup P, Ussher M, Harris TJ.

Arch Gerontol Geriatr. 2016 Nov-Dec;67:1-6. doi: 10.1016/j.archger.2016.06.006. Epub 2016 Jun 11.

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