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Items: 1 to 50 of 168

1.

Quantitative analysis of the impact of a human pathogenic mutation on the CCT5 chaperonin subunit using a proxy archaeal ortholog.

Spigolon D, Gallagher DT, Velazquez-Campoy A, Bulone D, Narang J, San Biagio PL, Cappello F, Macario AJL, Conway de Macario E, Robb FT.

Biochem Biophys Rep. 2017 Sep 1;12:66-71. doi: 10.1016/j.bbrep.2017.07.011. eCollection 2017 Dec.

2.

Editorial: Pathologic Conditions of the Human Nervous and Muscular Systems Associated with Mutant Chaperones: Molecular and Mechanistic Aspects.

Macario AJL, Conway de Macario E.

Front Mol Biosci. 2018 Feb 16;5:14. doi: 10.3389/fmolb.2018.00014. eCollection 2018. No abstract available.

3.

Chaperonin of Group I: Oligomeric Spectrum and Biochemical and Biological Implications.

Vilasi S, Bulone D, Caruso Bavisotto C, Campanella C, Marino Gammazza A, San Biagio PL, Cappello F, Conway de Macario E, Macario AJL.

Front Mol Biosci. 2018 Jan 25;4:99. doi: 10.3389/fmolb.2017.00099. eCollection 2017. Review.

4.

Immunohistochemistry of Human Hsp60 in Health and Disease: From Autoimmunity to Cancer.

Cappello F, Conway de Macario E, Rappa F, Zummo G, Macario AJL.

Methods Mol Biol. 2018;1709:293-305. doi: 10.1007/978-1-4939-7477-1_21.

PMID:
29177667
5.

HSP60 activity on human bronchial epithelial cells.

Sangiorgi C, Vallese D, Gnemmi I, Bucchieri F, Balbi B, Brun P, Leone A, Giordano A, Conway de Macario E, Macario AJ, Cappello F, Di Stefano A.

Int J Immunopathol Pharmacol. 2017 Dec;30(4):333-340. doi: 10.1177/0394632017734479. Epub 2017 Oct 4.

6.

Exosomal HSP60: a potentially useful biomarker for diagnosis, assessing prognosis, and monitoring response to treatment.

Caruso Bavisotto C, Cappello F, Macario AJL, Conway de Macario E, Logozzi M, Fais S, Campanella C.

Expert Rev Mol Diagn. 2017 Sep;17(9):815-822. doi: 10.1080/14737159.2017.1356230. Epub 2017 Jul 25. Review.

PMID:
28718351
7.

The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex (CubipyOXA) leads to cell death in NCI-H292 cancer cells.

Caruso Bavisotto C, Nikolic D, Marino Gammazza A, Barone R, Lo Cascio F, Mocciaro E, Zummo G, Conway de Macario E, Macario AJ, Cappello F, Giacalone V, Pace A, Barone G, Palumbo Piccionello A, Campanella C.

J Inorg Biochem. 2017 May;170:8-16. doi: 10.1016/j.jinorgbio.2017.02.004. Epub 2017 Feb 10.

PMID:
28212901
8.

Prokaryotic Chaperonins as Experimental Models for Elucidating Structure-Function Abnormalities of Human Pathogenic Mutant Counterparts.

Conway de Macario E, Robb FT, Macario AJ.

Front Mol Biosci. 2017 Jan 9;3:84. doi: 10.3389/fmolb.2016.00084. eCollection 2016. Review.

9.

Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence.

Marino Gammazza A, Campanella C, Barone R, Caruso Bavisotto C, Gorska M, Wozniak M, Carini F, Cappello F, D'Anneo A, Lauricella M, Zummo G, Conway de Macario E, Macario AJ, Di Felice V.

Cancer Lett. 2017 Jan 28;385:75-86. doi: 10.1016/j.canlet.2016.10.045. Epub 2016 Nov 9.

PMID:
27836734
10.

Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.

Rappa F, Pitruzzella A, Marino Gammazza A, Barone R, Mocciaro E, Tomasello G, Carini F, Farina F, Zummo G, Conway de Macario E, Macario AJ, Cappello F.

Cell Stress Chaperones. 2016 Sep;21(5):927-33. doi: 10.1007/s12192-016-0721-5. Epub 2016 Aug 4.

11.

Zebrafish as a Model for the Study of Chaperonopathies.

Bellipanni G, Cappello F, Scalia F, Conway de Macario E, Macario AJ, Giordano A.

J Cell Physiol. 2016 Oct;231(10):2107-14. doi: 10.1002/jcp.25319. Epub 2016 Feb 16. Review.

PMID:
26812965
12.

Skeletal muscle Heat shock protein 60 increases after endurance training and induces peroxisome proliferator-activated receptor gamma coactivator 1 α1 expression.

Barone R, Macaluso F, Sangiorgi C, Campanella C, Marino Gammazza A, Moresi V, Coletti D, Conway de Macario E, Macario AJ, Cappello F, Adamo S, Farina F, Zummo G, Di Felice V.

Sci Rep. 2016 Jan 27;6:19781. doi: 10.1038/srep19781.

13.

Alcoholic Liver Disease: A Mouse Model Reveals Protection by Lactobacillus fermentum.

Barone R, Rappa F, Macaluso F, Caruso Bavisotto C, Sangiorgi C, Di Paola G, Tomasello G, Di Felice V, Marcianò V, Farina F, Zummo G, Conway de Macario E, Macario AJ, Cocchi M, Cappello F, Marino Gammazza A.

Clin Transl Gastroenterol. 2016 Jan 21;7:e138. doi: 10.1038/ctg.2015.66.

14.

The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells.

Campanella C, D'Anneo A, Marino Gammazza A, Caruso Bavisotto C, Barone R, Emanuele S, Lo Cascio F, Mocciaro E, Fais S, Conway De Macario E, Macario AJ, Cappello F, Lauricella M.

Oncotarget. 2016 May 17;7(20):28849-67. doi: 10.18632/oncotarget.6680.

15.

Chaperone patterns in vernal keratoconjunctivitis are distinctive of cell and Hsp type and are modified by inflammatory stimuli.

Leonardi A, Tarricone E, Corrao S, Alaibac M, Corso AJ, Zavan B, Venier P, Conway de Macario E, Macario AJ, Di Stefano A, Cappello F, Brun P.

Allergy. 2016 Mar;71(3):403-11. doi: 10.1111/all.12814. Epub 2015 Dec 23.

PMID:
26613380
16.

CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.

Cabibi D, Conway de Macario E, Ingrao S, Porcasi R, Zucco F, Macario AJ, Cappello F, Rappa F.

Cell Stress Chaperones. 2016 Jan;21(1):131-7. doi: 10.1007/s12192-015-0646-4. Epub 2015 Oct 6.

17.

Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery.

Campanella C, Rappa F, Sciumè C, Marino Gammazza A, Barone R, Bucchieri F, David S, Curcurù G, Caruso Bavisotto C, Pitruzzella A, Geraci G, Modica G, Farina F, Zummo G, Fais S, Conway de Macario E, Macario AJ, Cappello F.

Cancer. 2015 Sep 15;121(18):3230-9. doi: 10.1002/cncr.29499. Epub 2015 Jun 8.

18.

Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto's thyroiditis patients based on the response of their PBMC with IL-2 and IFN-γ secretion to stimulation with Hsp60.

Tonello L, Conway de Macario E, Marino Gammazza A, Cocchi M, Gabrielli F, Zummo G, Cappello F, Macario AJ.

Cell Stress Chaperones. 2015 Mar;20(2):391-5. doi: 10.1007/s12192-014-0555-y. Epub 2014 Nov 19.

19.

Human Hsp60 with its mitochondrial import signal occurs in solution as heptamers and tetradecamers remarkably stable over a wide range of concentrations.

Vilasi S, Carrotta R, Mangione MR, Campanella C, Librizzi F, Randazzo L, Martorana V, Marino Gammazza A, Ortore MG, Vilasi A, Pocsfalvi G, Burgio G, Corona D, Palumbo Piccionello A, Zummo G, Bulone D, Conway de Macario E, Macario AJ, San Biagio PL, Cappello F.

PLoS One. 2014 May 15;9(5):e97657. doi: 10.1371/journal.pone.0097657. eCollection 2014.

20.

Hsp60 chaperonopathies and chaperonotherapy: targets and agents.

Cappello F, Marino Gammazza A, Palumbo Piccionello A, Campanella C, Pace A, Conway de Macario E, Macario AJ.

Expert Opin Ther Targets. 2014 Feb;18(2):185-208. doi: 10.1517/14728222.2014.856417. Epub 2013 Nov 29. Review.

PMID:
24286280
21.

Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis.

Marino Gammazza A, Rizzo M, Citarrella R, Rappa F, Campanella C, Bucchieri F, Patti A, Nikolic D, Cabibi D, Amico G, Conaldi PG, San Biagio PL, Montalto G, Farina F, Zummo G, Conway de Macario E, Macario AJ, Cappello F.

Cell Stress Chaperones. 2014 May;19(3):343-53. doi: 10.1007/s12192-013-0460-9. Epub 2013 Sep 22.

22.

Gut microbiota imbalance and chaperoning system malfunction are central to ulcerative colitis pathogenesis and can be counteracted with specifically designed probiotics: a working hypothesis.

Bellavia M, Tomasello G, Romeo M, Damiani P, Lo Monte AI, Lozio L, Campanella C, Marino Gammazza A, Rappa F, Zummo G, Cocchi M, Conway de Macario E, Macario AJ, Cappello F.

Med Microbiol Immunol. 2013 Dec;202(6):393-406. doi: 10.1007/s00430-013-0305-2. Epub 2013 Jul 18. Review.

PMID:
23864544
23.

Hsp10: anatomic distribution, functions, and involvement in human disease.

David S, Bucchieri F, Corrao S, Czarnecka AM, Campanella C, Farina F, Peri G, Tomasello G, Sciumè C, Modica G, La Rocca G, Anzalone R, Giuffrè M, Conway De Macario E, Macario AJ, Cappello F, Zummo G.

Front Biosci (Elite Ed). 2013 Jan 1;5:768-78. Review.

PMID:
23277031
24.

Hsp60 and human aging: Les liaisons dangereuses.

Cappello F, Conway de Macario E, Marino Gammazza A, Bonaventura G, Carini F, Czarnecka AM, Farina F, Zummo G, Macario AJ.

Front Biosci (Landmark Ed). 2013 Jan 1;18:626-37. Review.

PMID:
23276948
25.

Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy.

Tomasello G, Sciumé C, Rappa F, Rodolico V, Zerilli M, Martorana A, Cicero G, De Luca R, Damiani P, Accardo FM, Romeo M, Farina F, Bonaventura G, Modica G, Zummo G, Conway de Macario E, Macario AJ, Cappello F.

Eur J Histochem. 2011 Oct 24;55(4):e38. doi: 10.4081/ejh.2011.e38.

26.

Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study.

Rizzo M, Cappello F, Marfil R, Nibali L, Marino Gammazza A, Rappa F, Bonaventura G, Galindo-Moreno P, O'Valle F, Zummo G, Conway de Macario E, Macario AJ, Mesa F.

Cell Stress Chaperones. 2012 May;17(3):399-407. doi: 10.1007/s12192-011-0315-1. Epub 2012 Jan 4.

27.

Convergent sets of data from in vivo and in vitro methods point to an active role of Hsp60 in chronic obstructive pulmonary disease pathogenesis.

Cappello F, Caramori G, Campanella C, Vicari C, Gnemmi I, Zanini A, Spanevello A, Capelli A, La Rocca G, Anzalone R, Bucchieri F, D'Anna SE, Ricciardolo FL, Brun P, Balbi B, Carone M, Zummo G, Conway de Macario E, Macario AJ, Di Stefano A.

PLoS One. 2011;6(11):e28200. doi: 10.1371/journal.pone.0028200. Epub 2011 Nov 28.

28.

Hsp60: molecular anatomy and role in colorectal cancer diagnosis and treatment.

Cappello F, David S, Peri G, Farina F, Conway de Macario E, Macario AJ, Zummo G.

Front Biosci (Schol Ed). 2011 Jan 1;3:341-51. Review.

PMID:
21196380
29.

Chaperonopathies of senescence and the scrambling of interactions between the chaperoning and the immune systems.

Macario AJ, Cappello F, Zummo G, Conway de Macario E.

Ann N Y Acad Sci. 2010 Jun;1197:85-93. doi: 10.1111/j.1749-6632.2010.05187.x. Review.

PMID:
20536837
30.

Hsp60 and Hsp10 increase in colon mucosa of Crohn’s disease and ulcerative colitis.

Rodolico V, Tomasello G, Zerilli M, Martorana A, Pitruzzella A, Gammazza AM, David S, Zummo G, Damiani P, Accomando S, Conway de Macario E, Macario AJ, Cappello F.

Cell Stress Chaperones. 2010 Nov;15(6):877-84. doi: 10.1007/s12192-010-0196-8.

31.

Hsp60 and AChR cross-reactivity in myasthenia gravis: An update.

Cappello F, Marino Gammazza A, Zummo L, Conway de Macario E, Macario AJ.

J Neurol Sci. 2010 May 15;292(1-2):117-8. doi: 10.1016/j.jns.2010.02.021. Epub 2010 Mar 16. No abstract available.

PMID:
20236663
32.

Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes.

Mukherjee K, Conway de Macario E, Macario AJ, Brocchieri L.

BMC Evol Biol. 2010 Mar 1;10:64. doi: 10.1186/1471-2148-10-64.

33.

Hsp60 is actively secreted by human tumor cells.

Merendino AM, Bucchieri F, Campanella C, Marcianò V, Ribbene A, David S, Zummo G, Burgio G, Corona DF, Conway de Macario E, Macario AJ, Cappello F.

PLoS One. 2010 Feb 16;5(2):e9247. doi: 10.1371/journal.pone.0009247.

34.

Human Hsp10 and Early Pregnancy Factor (EPF) and their relationship and involvement in cancer and immunity: current knowledge and perspectives.

Corrao S, Campanella C, Anzalone R, Farina F, Zummo G, Conway de Macario E, Macario AJ, Cappello F, La Rocca G.

Life Sci. 2010 Jan 30;86(5-6):145-52. doi: 10.1016/j.lfs.2009.11.004. Epub 2009 Nov 12. Review.

PMID:
19913561
35.

Chlamydia trachomatis infection and anti-Hsp60 immunity: the two sides of the coin.

Cappello F, Conway de Macario E, Di Felice V, Zummo G, Macario AJ.

PLoS Pathog. 2009 Aug;5(8):e1000552. doi: 10.1371/journal.ppat.1000552. Epub 2009 Aug 28. Review.

36.

Upon oxidative stress, the antiapoptotic Hsp60/procaspase-3 complex persists in mucoepidermoid carcinoma cells.

Campanella C, Bucchieri F, Ardizzone NM, Marino Gammazza A, Montalbano A, Ribbene A, Di Felice V, Bellafiore M, David S, Rappa F, Marasà M, Peri G, Farina F, Czarnecka AM, Conway de Macario E, Macario AJ, Zummo G, Cappello F.

Eur J Histochem. 2008 Oct-Dec;52(4):221-8.

PMID:
19109096
37.

Methanogenic archaea in health and disease: a novel paradigm of microbial pathogenesis.

Conway de Macario E, Macario AJ.

Int J Med Microbiol. 2009 Feb;299(2):99-108. doi: 10.1016/j.ijmm.2008.06.011. Epub 2008 Aug 30. Review.

PMID:
18757236
38.

Hsp60 expression, new locations, functions and perspectives for cancer diagnosis and therapy.

Cappello F, Conway de Macario E, Marasà L, Zummo G, Macario AJ.

Cancer Biol Ther. 2008 Jun;7(6):801-9. Epub 2008 May 13. Review.

PMID:
18497565
39.

hsp70 genes in the human genome: Conservation and differentiation patterns predict a wide array of overlapping and specialized functions.

Brocchieri L, Conway de Macario E, Macario AJ.

BMC Evol Biol. 2008 Jan 23;8:19. doi: 10.1186/1471-2148-8-19.

40.

Chaperonopathies by defect, excess, or mistake.

Macario AJ, Conway de Macario E.

Ann N Y Acad Sci. 2007 Oct;1113:178-91. Epub 2007 May 4. Review.

PMID:
17483209
41.

Chaperonopathies and chaperonotherapy.

Macario AJ, Conway de Macario E.

FEBS Lett. 2007 Jul 31;581(19):3681-8. Epub 2007 Apr 24. Review.

42.

Molecular chaperones: multiple functions, pathologies, and potential applications.

Macario AJ, Conway de Macario E.

Front Biosci. 2007 Jan 1;12:2588-600. Review.

PMID:
17127265
43.

Chaperonomics, a new tool to study ageing and associated diseases.

Brocchieri L, Conway de Macario E, Macario AJ.

Mech Ageing Dev. 2007 Jan;128(1):125-36. Epub 2006 Nov 22. Review.

PMID:
17123587
44.

Evolution of a protein-folding machine: genomic and evolutionary analyses reveal three lineages of the archaeal hsp70(dnaK) gene.

Macario AJ, Brocchieri L, Shenoy AR, Conway de Macario E.

J Mol Evol. 2006 Jul;63(1):74-86. Epub 2006 Jun 20.

PMID:
16788741
45.

Sick chaperones, cellular stress, and disease.

Macario AJ, Conway de Macario E.

N Engl J Med. 2005 Oct 6;353(14):1489-501. Review. No abstract available.

PMID:
16207851
46.

The pathology of cellular anti-stress mechanisms: a new frontier.

Macario AJ, Conway de Macario E.

Stress. 2004 Dec;7(4):243-9. Review.

PMID:
16019589
47.

Novel chaperonins in a prokaryote.

Maeder DL, Macario AJ, Conway de Macario E.

J Mol Evol. 2005 Mar;60(3):409-16.

PMID:
15871051
48.

Genetic disorders involving molecular-chaperone genes: a perspective.

Macario AJ, Grippo TM, Conway de Macario E.

Genet Med. 2005 Jan;7(1):3-12. Review.

PMID:
15654222
49.

Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis.

Hendrickson EL, Kaul R, Zhou Y, Bovee D, Chapman P, Chung J, Conway de Macario E, Dodsworth JA, Gillett W, Graham DE, Hackett M, Haydock AK, Kang A, Land ML, Levy R, Lie TJ, Major TA, Moore BC, Porat I, Palmeiri A, Rouse G, Saenphimmachak C, Söll D, Van Dien S, Wang T, Whitman WB, Xia Q, Zhang Y, Larimer FW, Olson MV, Leigh JA.

J Bacteriol. 2004 Oct;186(20):6956-69.

50.

Evolution of assisted protein folding: the distribution of the main chaperoning systems within the phylogenetic domain archaea.

Macario AJ, Malz M, Conway de Macario E.

Front Biosci. 2004 May 1;9:1318-32. Review.

PMID:
14977547

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