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Items: 1 to 50 of 254

1.

Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation.

Scharf GM, Kilian K, Cordero J, Wang Y, Grund A, Hofmann M, Froese N, Wang X, Kispert A, Kist R, Conway SJ, Geffers R, Wollert KC, Dobreva G, Bauersachs J, Heineke J.

JCI Insight. 2019 Jul 16;5. pii: 126721. doi: 10.1172/jci.insight.126721.

PMID:
31310588
2.

Periostin forms a functional complex with IgA in human serum.

Ono J, Takai M, Kamei A, Nunomura S, Nanri Y, Yoshihara T, Ohta S, Yasuda K, Conway SJ, Yokosaki Y, Izuhara K.

Allergol Int. 2019 Jul 1. pii: S1323-8930(19)30083-8. doi: 10.1016/j.alit.2019.05.014. [Epub ahead of print]

3.

Interaction of the Mechanosensitive Channel, MscS, with the Membrane Bilayer through Lipid Intercalation into Grooves and Pockets.

Rasmussen T, Rasmussen A, Yang L, Kaul C, Black S, Galbiati H, Conway SJ, Miller S, Blount P, Booth IR.

J Mol Biol. 2019 Jun 4. pii: S0022-2836(19)30333-X. doi: 10.1016/j.jmb.2019.05.043. [Epub ahead of print]

4.

Phenotypic and biochemical analysis of an international cohort of individuals with variants in NAA10 and NAA15.

Cheng H, Gottlieb L, Marchi E, Kleyner R, Bhardwaj P, Rope AF, Rosenheck S, Moutton S, Philippe C, Eyaid W, Alkuraya FS, Toribio J, Mena R, Prada CE, Stessman H, Bernier R, Wermuth M, Kauffmann B, Blaumeiser B, Kooy RF, Baralle D, Mancini GMS, Conway SJ, Xia F, Chen Z, Meng L, Mihajlovic L, Marmorstein R, Lyon GJ.

Hum Mol Genet. 2019 May 25. pii: ddz111. doi: 10.1093/hmg/ddz111. [Epub ahead of print]

PMID:
31127942
5.

Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart.

Huang S, Chen B, Su Y, Alex L, Humeres C, Shinde AV, Conway SJ, Frangogiannis NG.

J Mol Cell Cardiol. 2019 Jul;132:84-97. doi: 10.1016/j.yjmcc.2019.05.006. Epub 2019 May 11.

PMID:
31085202
6.

PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress.

Der Vartanian A, Quétin M, Michineau S, Auradé F, Hayashi S, Dubois C, Rocancourt D, Drayton-Libotte B, Szegedi A, Buckingham M, Conway SJ, Gervais M, Relaix F.

Cell Stem Cell. 2019 Jun 6;24(6):958-973.e9. doi: 10.1016/j.stem.2019.03.019. Epub 2019 Apr 18.

PMID:
31006622
7.

Fibroblast Primary Cilia Are Required for Cardiac Fibrosis.

Villalobos E, Criollo A, Schiattarella GG, Altamirano F, French KM, May HI, Jiang N, Nguyen NUN, Romero D, Roa JC, García L, Diaz-Araya G, Morselli E, Ferdous A, Conway SJ, Sadek HA, Gillette TG, Lavandero S, Hill JA.

Circulation. 2019 May 14;139(20):2342-2357. doi: 10.1161/CIRCULATIONAHA.117.028752.

PMID:
30818997
8.

Postacute Care Transitions: Developing a Skilled Nursing Facility Collaborative within an Academic Health System.

Conway SJ, Parekh AK, Hughes AH, Sylvester C, Himmelrich S, Hebert LC, Doyle D, Bellantoni M, Berkowitz SA.

J Hosp Med. 2019 Mar;14(3):174-177. doi: 10.12788/jhm.3117. No abstract available.

PMID:
30811325
9.

Protective Effects of Activated Myofibroblasts in the Pressure-Overloaded Myocardium Are Mediated Through Smad-Dependent Activation of a Matrix-Preserving Program.

Russo I, Cavalera M, Huang S, Su Y, Hanna A, Chen B, Shinde AV, Conway SJ, Graff J, Frangogiannis NG.

Circ Res. 2019 Apr 12;124(8):1214-1227. doi: 10.1161/CIRCRESAHA.118.314438.

PMID:
30686120
10.

Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice.

Imaeda A, Tanaka S, Tonegawa K, Fuchigami S, Obana M, Maeda M, Kihara M, Kiyonari H, Conway SJ, Fujio Y, Nakayama H.

Biochem Biophys Res Commun. 2019 Feb 26;510(1):149-155. doi: 10.1016/j.bbrc.2019.01.070. Epub 2019 Jan 23.

PMID:
30683314
11.

Chemical epigenetics: the impact of chemical- and chemical biology techniques on bromodomain target validation.

Schiedel M, Moroglu M, Ascough DMH, Chamberlain AER, Kamps JJAG, Sekirnik AR, Conway SJ.

Angew Chem Int Ed Engl. 2019 Jan 11. doi: 10.1002/anie.201812164. [Epub ahead of print]

PMID:
30633431
12.

Patient isolation for infection control and patient experience.

Siddiqui ZK, Conway SJ, Abusamaan M, Bertram A, Berry SA, Allen L, Apfel A, Farley H, Zhu J, Wu AW, Brotman DJ.

Infect Control Hosp Epidemiol. 2018 Dec 18:1-6. doi: 10.1017/ice.2018.324. [Epub ahead of print]

PMID:
30560748
13.

Hypoxia-Activated, Small-Molecule-Induced Gene Expression.

Collins SL, Saha J, Bouchez LC, Hammond EM, Conway SJ.

ACS Chem Biol. 2018 Dec 21;13(12):3354-3360. doi: 10.1021/acschembio.8b00858. Epub 2018 Dec 7.

PMID:
30451487
14.

LEAFY maintains apical stem cell activity during shoot development in the fern Ceratopteris richardii.

Plackett AR, Conway SJ, Hewett Hazelton KD, Rabbinowitsch EH, Langdale JA, Di Stilio VS.

Elife. 2018 Oct 24;7. pii: e39625. doi: 10.7554/eLife.39625.

15.

Small molecules as tools to study the chemical epigenetics of lysine acetylation.

Schiedel M, Conway SJ.

Curr Opin Chem Biol. 2018 Aug;45:166-178. doi: 10.1016/j.cbpa.2018.06.015. Epub 2018 Jun 27. Review.

PMID:
29958150
16.

Sca-1+ cardiac fibroblasts promote development of heart failure.

Chen G, Bracamonte-Baran W, Diny NL, Hou X, Talor MV, Fu K, Liu Y, Davogustto G, Vasquez H, Taegtmeyer H, Frazier OH, Waisman A, Conway SJ, Wan F, Čiháková D.

Eur J Immunol. 2018 Sep;48(9):1522-1538. doi: 10.1002/eji.201847583. Epub 2018 Jul 18.

PMID:
29953616
17.

Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo.

Nakazeki F, Nishiga M, Horie T, Nishi H, Nakashima Y, Baba O, Kuwabara Y, Nishino T, Nakao T, Ide Y, Koyama S, Kimura M, Tsuji S, Sowa N, Yoshida S, Conway SJ, Yanagita M, Kimura T, Ono K.

Sci Rep. 2018 Jun 4;8(1):8553. doi: 10.1038/s41598-018-27009-9.

18.

High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions.

Phillips JO, Butt LE, Henderson CA, Devonshire M, Healy J, Conway SJ, Locker N, Pickford AR, Vincent HA, Callaghan AJ.

Nucleic Acids Res. 2018 Aug 21;46(14):e86. doi: 10.1093/nar/gky410.

19.

BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability.

Jennings LE, Schiedel M, Hewings DS, Picaud S, Laurin CMC, Bruno PA, Bluck JP, Scorah AR, See L, Reynolds JK, Moroglu M, Mistry IN, Hicks A, Guzanov P, Clayton J, Evans CNG, Stazi G, Biggin PC, Mapp AK, Hammond EM, Humphreys PG, Filippakopoulos P, Conway SJ.

Bioorg Med Chem. 2018 Jul 15;26(11):2937-2957. doi: 10.1016/j.bmc.2018.05.003. Epub 2018 May 15.

20.

Megakaryocyte and Osteoblast Interactions Modulate Bone Mass and Hematopoiesis.

Alvarez MB, Xu L, Childress PJ, Maupin KA, Mohamad SF, Chitteti BR, Himes E, Olivos DJ 3rd, Cheng YH, Conway SJ, Srour EF, Kacena MA.

Stem Cells Dev. 2018 May 15;27(10):671-682. doi: 10.1089/scd.2017.0178.

21.

Building a Medicaid Ambulatory Complex Care Program Within an Urban Medical Home.

Sander LD, Albert M, Okeke N, Kravet S, Rediger K, Conway SJ, McGuire MJ.

Popul Health Manag. 2018 Dec;21(6):446-453. doi: 10.1089/pop.2017.0200. Epub 2018 Apr 5.

PMID:
29620961
22.

The IL-13/periostin/IL-24 pathway causes epidermal barrier dysfunction in allergic skin inflammation.

Mitamura Y, Nunomura S, Nanri Y, Ogawa M, Yoshihara T, Masuoka M, Tsuji G, Nakahara T, Hashimoto-Hachiya A, Conway SJ, Furue M, Izuhara K.

Allergy. 2018 Sep;73(9):1881-1891. doi: 10.1111/all.13437.

PMID:
29528494
23.

Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin.

Duchamp de Lageneste O, Julien A, Abou-Khalil R, Frangi G, Carvalho C, Cagnard N, Cordier C, Conway SJ, Colnot C.

Nat Commun. 2018 Feb 22;9(1):773. doi: 10.1038/s41467-018-03124-z.

24.

Constitutive overexpression of periostin delays wound healing in mouse skin.

Nunomura S, Nanri Y, Ogawa M, Arima K, Mitamura Y, Yoshihara T, Hasuwa H, Conway SJ, Izuhara K.

Wound Repair Regen. 2018 Jan;26(1):6-15. doi: 10.1111/wrr.12616. Epub 2018 Mar 7.

25.

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2.

Wahle BM, Hawley ET, He Y, Smith AE, Yuan J, Masters AR, Jones DR, Gehlhausen JR, Park SJ, Conway SJ, Clapp DW, Yates CW.

Oncotarget. 2017 Oct 24;9(1):718-725. doi: 10.18632/oncotarget.22002. eCollection 2018 Jan 2.

26.

Strategic Review Process for an Accountable Care Organization and Emerging Accountable Care Best Practices.

Conway SJ, Himmelrich S, Feeser SA, Flynn JA, Kravet SJ, Bailey J, Hebert LC, Donovan SH, Kachur SG, Brown PMC, Baumgartner WA, Berkowitz SA.

Popul Health Manag. 2018 Oct;21(5):357-365. doi: 10.1089/pop.2017.0149. Epub 2018 Feb 2.

PMID:
29393824
27.

Opposing Actions of Fibroblast and Cardiomyocyte Smad3 Signaling in the Infarcted Myocardium.

Kong P, Shinde AV, Su Y, Russo I, Chen B, Saxena A, Conway SJ, Graff JM, Frangogiannis NG.

Circulation. 2018 Feb 13;137(7):707-724. doi: 10.1161/CIRCULATIONAHA.117.029622. Epub 2017 Dec 11.

28.

Primary Care Provider Preferences for Communication with Inpatient Teams: One Size Does Not Fit All.

Lawrence D, Shah AK, Lee EK, Conway SJ, Ramkumar MK, James HJ, Queale WS, Keller SC, Biddison EL, Gregg PC, Ashar BH, Desai SV, Brotman DJ, Berry SA.

J Hosp Med. 2018 Mar 1;13(3):177-178. doi: 10.12788/jhm.2874. Epub 2017 Nov 8. No abstract available.

PMID:
29154380
29.

Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies.

Poulsen ET, Runager K, Nielsen NS, Lukassen MV, Thomsen K, Snider P, Simmons O, Vorum H, Conway SJ, Enghild JJ.

FEBS J. 2018 Jan;285(1):101-114. doi: 10.1111/febs.14321. Epub 2017 Nov 23.

30.

The triggering factors of the Móafellshyrna debris slide in northern Iceland: Intense precipitation, earthquake activity and thawing of mountain permafrost.

Sæmundsson Þ, Morino C, Helgason JK, Conway SJ, Pétursson HG.

Sci Total Environ. 2018 Apr 15;621:1163-1175. doi: 10.1016/j.scitotenv.2017.10.111. Epub 2017 Oct 31.

PMID:
29096954
31.

Water induced sediment levitation enhances downslope transport on Mars.

Raack J, Conway SJ, Herny C, Balme MR, Carpy S, Patel MR.

Nat Commun. 2017 Oct 27;8(1):1151. doi: 10.1038/s41467-017-01213-z.

32.

Electrical coupling between ventricular myocytes and myofibroblasts in the infarcted mouse heart.

Rubart M, Tao W, Lu XL, Conway SJ, Reuter SP, Lin SF, Soonpaa MH.

Cardiovasc Res. 2018 Mar 1;114(3):389-400. doi: 10.1093/cvr/cvx163.

33.

TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury.

Schwanekamp JA, Lorts A, Sargent MA, York AJ, Grimes KM, Fischesser DM, Gokey JJ, Whitsett JA, Conway SJ, Molkentin JD.

PLoS One. 2017 Jul 27;12(7):e0181945. doi: 10.1371/journal.pone.0181945. eCollection 2017.

34.

Clinical Advances of Hypoxia-Activated Prodrugs in Combination With Radiation Therapy.

Mistry IN, Thomas M, Calder EDD, Conway SJ, Hammond EM.

Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1183-1196. doi: 10.1016/j.ijrobp.2017.03.024. Epub 2017 Mar 22. Review.

35.

Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System.

Pliotas C, Grayer SC, Ekkerman S, Chan AKN, Healy J, Marius P, Bartlett W, Khan A, Cortopassi WA, Chandler SA, Rasmussen T, Benesch JLP, Paton RS, Claridge TDW, Miller S, Booth IR, Naismith JH, Conway SJ.

Biochemistry. 2017 Aug 15;56(32):4219-4234. doi: 10.1021/acs.biochem.7b00300. Epub 2017 Aug 4.

36.

CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes.

O'Connor LJ, Mistry IN, Collins SL, Folkes LK, Brown G, Conway SJ, Hammond EM.

ACS Cent Sci. 2017 Jan 25;3(1):20-30. doi: 10.1021/acscentsci.6b00276. Epub 2016 Dec 19.

37.

Pyocyanin degradation by a tautomerizing demethylase inhibits Pseudomonas aeruginosa biofilms.

Costa KC, Glasser NR, Conway SJ, Newman DK.

Science. 2017 Jan 13;355(6321):170-173. doi: 10.1126/science.aag3180. Epub 2016 Dec 8.

38.

Improving Professional Development to Enhance Reading Outcomes for Students in Special Education.

Lemons CJ, Otaiba SA, Conway SJ, Mellado De La Cruz V.

New Dir Child Adolesc Dev. 2016 Dec;2016(154):87-104. doi: 10.1002/cad.20177.

PMID:
27922218
39.

MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol.

Nishiga M, Horie T, Kuwabara Y, Nagao K, Baba O, Nakao T, Nishino T, Hakuno D, Nakashima Y, Nishi H, Nakazeki F, Ide Y, Koyama S, Kimura M, Hanada R, Nakamura T, Inada T, Hasegawa K, Conway SJ, Kita T, Kimura T, Ono K.

Circ Res. 2017 Mar 3;120(5):835-847. doi: 10.1161/CIRCRESAHA.116.309528. Epub 2016 Dec 5.

PMID:
27920122
40.

Editorial overview: Chemical genetics and epigenetics.

Fujimori DG, Conway SJ.

Curr Opin Chem Biol. 2016 Aug;33:vi-vii. doi: 10.1016/j.cbpa.2016.08.008. No abstract available.

PMID:
27614207
41.

Influence of periostin-positive cell-specific Klf5 deletion on aortic thickening in DOCA-salt hypertensive mice.

Zempo H, Suzuki JI, Ogawa M, Watanabe R, Fujiu K, Manabe I, Conway SJ, Taniyama Y, Morishita R, Hirata Y, Isobe M, Nagai R.

Hypertens Res. 2016 Nov;39(11):764-768. doi: 10.1038/hr.2016.65. Epub 2016 Jun 23.

42.

Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3.

Sekirnik Née Measures AR, Hewings DS, Theodoulou NH, Jursins L, Lewendon KR, Jennings LE, Rooney TP, Heightman TD, Conway SJ.

Angew Chem Int Ed Engl. 2016 Jul 11;55(29):8353-7. doi: 10.1002/anie.201602908. Epub 2016 Jun 6.

43.

Periostin as a multifunctional modulator of the wound healing response.

Walker JT, McLeod K, Kim S, Conway SJ, Hamilton DW.

Cell Tissue Res. 2016 Sep;365(3):453-65. doi: 10.1007/s00441-016-2426-6. Epub 2016 May 28. Review.

44.

Bone Morphogenetic Protein Signaling Is Required for Aortic Valve Calcification.

Gomez-Stallons MV, Wirrig-Schwendeman EE, Hassel KR, Conway SJ, Yutzey KE.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1398-405. doi: 10.1161/ATVBAHA.116.307526. Epub 2016 May 19.

45.

Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice.

Kaur H, Takefuji M, Ngai CY, Carvalho J, Bayer J, Wietelmann A, Poetsch A, Hoelper S, Conway SJ, Möllmann H, Looso M, Troidl C, Offermanns S, Wettschureck N.

Circ Res. 2016 Jun 10;118(12):1906-17. doi: 10.1161/CIRCRESAHA.116.308643. Epub 2016 May 2. Erratum in: Circ Res. 2016 Sep 16;119(7):e109.

PMID:
27140435
46.

The photochemical thiol-ene reaction as a versatile method for the synthesis of glutathione S-conjugates targeting the bacterial potassium efflux system Kef.

Healy J, Rasmussen T, Miller S, Booth IR, Conway SJ.

Org Chem Front. 2016 Apr 29;3(4):439-446. Epub 2016 Feb 26.

47.

Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction.

Sugiyama A, Kanno K, Nishimichi N, Ohta S, Ono J, Conway SJ, Izuhara K, Yokosaki Y, Tazuma S.

J Gastroenterol. 2016 Dec;51(12):1161-1174. Epub 2016 Apr 4.

PMID:
27039906
48.

Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs.

O'Connor LJ, Cazares-Körner C, Saha J, Evans CN, Stratford MR, Hammond EM, Conway SJ.

Nat Protoc. 2016 Apr;11(4):781-94. doi: 10.1038/nprot.2016.034. Epub 2016 Mar 24.

PMID:
27010756
49.

Restricted Pax3 Deletion within the Neural Tube Results in Congenital Hydrocephalus.

Zhou HM, Conway SJ.

J Dev Biol. 2016 Mar;4(1). pii: 7. Epub 2016 Feb 1.

50.

Initial Suppression of Transforming Growth Factor-β Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia.

Ahlfeld SK, Wang J, Gao Y, Snider P, Conway SJ.

Am J Pathol. 2016 Apr;186(4):777-93. doi: 10.1016/j.ajpath.2015.11.024. Epub 2016 Feb 13.

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