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Items: 36

1.

4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: part 2. Pyridazine-based analogs.

Yang SM, Tang Y, Rano T, Lu H, Kuo GH, Gaul MD, Li Y, Ho G, Lang W, Conway JG, Liang Y, Lenhard JM, Demarest KT, Murray WV.

Bioorg Med Chem Lett. 2014 Mar 1;24(5):1437-41. doi: 10.1016/j.bmcl.2013.12.075. Epub 2013 Dec 27.

PMID:
24405703
2.

4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: urea-based analogs.

Yang SM, Tang Y, Zhang R, Lu H, Kuo GH, Gaul MD, Li Y, Ho G, Conway JG, Liang Y, Lenhard JM, Demarest KT, Murray WV.

Bioorg Med Chem Lett. 2013 Dec 15;23(24):6773-6. doi: 10.1016/j.bmcl.2013.09.096. Epub 2013 Oct 9.

PMID:
24153205
3.

Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats.

Conway JG, Pink H, Bergquist ML, Han B, Depee S, Tadepalli S, Lin P, Crumrine RC, Binz J, Clark RL, Selph JL, Stimpson SA, Hutchins JT, Chamberlain SD, Brodie TA.

J Pharmacol Exp Ther. 2008 Jul;326(1):41-50. doi: 10.1124/jpet.107.129429. Epub 2008 Apr 23.

PMID:
18434589
4.

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

Conway JG, McDonald B, Parham J, Keith B, Rusnak DW, Shaw E, Jansen M, Lin P, Payne A, Crosby RM, Johnson JH, Frick L, Lin MH, Depee S, Tadepalli S, Votta B, James I, Fuller K, Chambers TJ, Kull FC, Chamberlain SD, Hutchins JT.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16078-83. Epub 2005 Oct 25.

5.

Regulation of TNF-alpha secretion by a specific melanocortin-1 receptor peptide agonist.

Ignar DM, Andrews JL, Jansen M, Eilert MM, Pink HM, Lin P, Sherrill RG, Szewczyk JR, Conway JG.

Peptides. 2003 May;24(5):709-16.

PMID:
12895657
6.

Design of selective and soluble inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).

Rabinowitz MH, Andrews RC, Becherer JD, Bickett DM, Bubacz DG, Conway JG, Cowan DJ, Gaul M, Glennon K, Lambert MH, Leesnitzer MA, McDougald DL, Moss ML, Musso DL, Rizzolio MC.

J Med Chem. 2001 Nov 22;44(24):4252-67.

PMID:
11708926
7.

N-hydroxyformamide peptidomimetics as TACE/matrix metalloprotease inhibitors: oral activity via P1' isobutyl substitution.

Musso DL, Andersen MW, Andrews RC, Austin R, Beaudet EJ, Becherer JD, Bubacz DG, Bickett DM, Chan JH, Conway JG, Cowan DJ, Gaul MD, Glennon KC, Hedeen KM, Lambert MH, Leesnitzer MA, McDougald DL, Mitchell JL, Moss ML, Rabinowitz MH, Rizzolio MC, Schaller LT, Stanford JB, Tippin T, Warner JR, Whitesell LG, Wiethe RW.

Bioorg Med Chem Lett. 2001 Aug 20;11(16):2147-51.

PMID:
11514157
8.

Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases.

Conway JG, Andrews RC, Beaudet B, Bickett DM, Boncek V, Brodie TA, Clark RL, Crumrine RC, Leenitzer MA, McDougald DL, Han B, Hedeen K, Lin P, Milla M, Moss M, Pink H, Rabinowitz MH, Tippin T, Scates PW, Selph J, Stimpson SA, Warner J, Becherer JD.

J Pharmacol Exp Ther. 2001 Sep;298(3):900-8.

PMID:
11504783
9.

Effect of matrix metalloproteinase inhibitors on tumor growth and spontaneous metastasis.

Conway JG, Trexler SJ, Wakefield JA, Marron BE, Emerson DL, Bickett DM, Deaton DN, Garrison D, Elder M, McElroy A, Willmott N, Dockerty AJ, McGeehan GM.

Clin Exp Metastasis. 1996 Mar;14(2):115-24.

PMID:
8605725
10.
11.

Inhibition of cartilage and bone destruction in adjuvant arthritis in the rat by a matrix metalloproteinase inhibitor.

Conway JG, Wakefield JA, Brown RH, Marron BE, Sekut L, Stimpson SA, McElroy A, Menius JA, Jeffreys JJ, Clark RL, et al.

J Exp Med. 1995 Aug 1;182(2):449-57.

12.

Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor.

McGeehan GM, Becherer JD, Bast RC Jr, Boyer CM, Champion B, Connolly KM, Conway JG, Furdon P, Karp S, Kidao S, et al.

Nature. 1994 Aug 18;370(6490):558-61.

PMID:
8052311
13.

Intensities of electronic Raman scattering between crystal-field levels of Ce3+ in LuPO4: Nonresonant and near-resonant excitation.

Williams GM, Becker PC, Conway JG, Edelstein N, Boatner LA, Abraham MM.

Phys Rev B Condens Matter. 1989 Aug 15;40(6):4132-4142. No abstract available.

PMID:
9992385
14.

Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643.

Conway JG, Tomaszewski KE, Olson MJ, Cattley RC, Marsman DS, Popp JA.

Carcinogenesis. 1989 Mar;10(3):513-9.

PMID:
2924396
15.

Possible mechanisms in hepatocarcinogenesis by the peroxisome proliferator di(2-ethylhexyl)phthalate.

Conway JG, Cattley RC, Popp JA, Butterworth BE.

Drug Metab Rev. 1989;21(1):65-102. Review. No abstract available.

PMID:
2696637
17.
20.

Carcinogen treatment increases glutathione hydrolysis by gamma-glutamyl transpeptidase.

Conway JG, Neptun DA, Garvey LK, Popp JA.

Carcinogenesis. 1987 Jul;8(7):999-1004.

PMID:
2885102
21.
22.

EPR and optical-absorption studies of Cmsup3+ in YPO4 and LuPO4 single crystals.

Abraham MM, Boatner LA, Finch CB, Kot WK, Conway JG, Shalimoff GV, Edelstein NM.

Phys Rev B Condens Matter. 1987 Mar 1;35(7):3057-3061. No abstract available.

PMID:
9941800
23.

Stimulation of mixed-function oxidation by NADPH in perfused mouse livers. Studies with saponin-permeabilized tissue.

Wu YR, Conway JG, Kauffman FC, Thurman RG.

Biochem Pharmacol. 1986 Oct 15;35(20):3607-12.

PMID:
3768043
24.
25.

Microcirculation in periportal and pericentral regions of lobule in perfused rat liver.

Conway JG, Popp JA, Thurman RG.

Am J Physiol. 1985 Oct;249(4 Pt 1):G449-56.

PMID:
2413767
26.

Microcirculation of hepatic nodules from diethylnitrosamine-treated rats.

Conway JG, Popp JA, Thurman RG.

Cancer Res. 1985 Aug;45(8):3620-5.

27.
28.

Glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the liver lobule.

Conway JG, Kauffman FC, Tsukada T, Thurman RG.

Mol Pharmacol. 1984 May;25(3):487-93.

PMID:
6427600
29.

Effect of size on portal circulation of hepatic nodules from carcinogen-treated rats.

Conway JG, Popp JA, Ji S, Thurman RG.

Cancer Res. 1983 Jul;43(7):3374-8.

30.
31.

Metabolic heterogeneity in the perfused rat liver.

Thurman RG, Kauffman FC, Ji S, Lemasters JJ, Conway JG, Belinsky SA, Kashiwagi T, Matsamura T.

Pharmacol Biochem Behav. 1983;18 Suppl 1:415-9.

PMID:
6356163
32.

Rates of sulfation and glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the liver lobule.

Conway JG, Kauffman FC, Ji S, Thurman RG.

Mol Pharmacol. 1982 Sep;22(2):509-16. No abstract available.

PMID:
7144740
33.

Immunohistochemical studies of cyclic guanosine monophosphate and nuclear function.

Rosenberg EM, Conway JG, Tucci SM, Doucet EW.

J Clin Invest. 1980 Oct;66(4):832-42.

34.

Associative ionization of laser-excited Rydberg states in strontium vapor.

Worden EF, Paisner JA, Conway JG.

Opt Lett. 1978 Oct 1;3(4):156-8.

PMID:
19684730
35.

Emission spectrum of californium.

CONWAY JG, HULET EK, MORROWRJ.

Osaka City Med J. 1962 Feb;11:222. No abstract available.

PMID:
13881026
36.

The extraction of ferric chloride by isopropyl ether.

NACHTRIEB NH, CONWAY JG.

J Am Chem Soc. 1948 Nov;70(11):3547-52. No abstract available.

PMID:
18102892

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