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Items: 1 to 50 of 118

1.

Capsid expansion of bacteriophage T5 revealed by high resolution cryoelectron microscopy.

Huet A, Duda RL, Boulanger P, Conway JF.

Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21037-21046. doi: 10.1073/pnas.1909645116. Epub 2019 Oct 2.

PMID:
31578255
2.

Mitochondrial fatty acid oxidation and the electron transport chain comprise a multifunctional mitochondrial protein complex.

Wang Y, Palmfeldt J, Gregersen N, Makhov AM, Conway JF, Wang M, McCalley SP, Basu S, Alharbi H, St Croix C, Calderon MJ, Watkins S, Vockley J.

J Biol Chem. 2019 Aug 16;294(33):12380-12391. doi: 10.1074/jbc.RA119.008680. Epub 2019 Jun 24.

PMID:
31235473
3.

Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors.

Gaydosik AM, Tabib T, Geskin LJ, Bayan CA, Conway JF, Lafyatis R, Fuschiotti P.

Clin Cancer Res. 2019 Jul 15;25(14):4443-4454. doi: 10.1158/1078-0432.CCR-19-0148. Epub 2019 Apr 22.

PMID:
31010835
4.

The Apical Region of the Herpes Simplex Virus Major Capsid Protein Promotes Capsid Maturation.

Ruhge LL, Huet AGE, Conway JF, Smith GA.

J Virol. 2018 Aug 29;92(18). pii: e00821-18. doi: 10.1128/JVI.00821-18. Print 2018 Sep 15.

5.

Proteomic profiling of extracellular vesicles released from vascular smooth muscle cells during initiation of phosphate-induced mineralization.

Chaudhary SC, Khalid S, Smethurst V, Monier D, Mobley J, Huet A, Conway JF, Napierala D.

Connect Tissue Res. 2018 Dec;59(sup1):55-61. doi: 10.1080/03008207.2018.1444759.

PMID:
29471680
6.

High-Resolution Structure Analysis of Antibody V5 and U4 Conformational Epitopes on Human Papillomavirus 16.

Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

Viruses. 2017 Dec 6;9(12). pii: E374. doi: 10.3390/v9120374.

7.

Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold.

Hua J, Huet A, Lopez CA, Toropova K, Pope WH, Duda RL, Hendrix RW, Conway JF.

MBio. 2017 Oct 17;8(5). pii: e01579-17. doi: 10.1128/mBio.01579-17.

8.

Cryo-EM maps reveal five-fold channel structures and their modification by gatekeeper mutations in the parvovirus minute virus of mice (MVM) capsid.

Subramanian S, Organtini LJ, Grossman A, Domeier PP, Cifuente JO, Makhov AM, Conway JF, D'Abramo A Jr, Cotmore SF, Tattersall P, Hafenstein S.

Virology. 2017 Oct;510:216-223. doi: 10.1016/j.virol.2017.07.015. Epub 2017 Jul 24.

9.

Herpesvirus Capsid Assembly and DNA Packaging.

Heming JD, Conway JF, Homa FL.

Adv Anat Embryol Cell Biol. 2017;223:119-142. doi: 10.1007/978-3-319-53168-7_6. Review.

10.

The C Terminus of the Herpes Simplex Virus UL25 Protein Is Required for Release of Viral Genomes from Capsids Bound to Nuclear Pores.

Huffman JB, Daniel GR, Falck-Pedersen E, Huet A, Smith GA, Conway JF, Homa FL.

J Virol. 2017 Jul 12;91(15). pii: e00641-17. doi: 10.1128/JVI.00641-17. Print 2017 Aug 1.

11.

Erratum: High affinity anchoring of the decoration protein pb10 onto the bacteriophage T5 capsid.

Vernhes E, Renouard M, Gilquin B, Cuniasse P, Durand D, England P, Hoos S, Huet A, Conway JF, Glukhov A, Ksenzenko V, Jacquet E, Nhiri N, Zinn-Justin S, Boulanger P.

Sci Rep. 2017 Apr 28;7:43977. doi: 10.1038/srep43977. No abstract available.

12.

High affinity anchoring of the decoration protein pb10 onto the bacteriophage T5 capsid.

Vernhes E, Renouard M, Gilquin B, Cuniasse P, Durand D, England P, Hoos S, Huet A, Conway JF, Glukhov A, Ksenzenko V, Jacquet E, Nhiri N, Zinn-Justin S, Boulanger P.

Sci Rep. 2017 Feb 6;7:41662. doi: 10.1038/srep41662. Erratum in: Sci Rep. 2017 Apr 28;7:43977.

13.

Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site.

Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

Structure. 2017 Feb 7;25(2):253-263. doi: 10.1016/j.str.2016.12.001. Epub 2017 Jan 5.

14.

Honey Bee Deformed Wing Virus Structures Reveal that Conformational Changes Accompany Genome Release.

Organtini LJ, Shingler KL, Ashley RE, Capaldi EA, Durrani K, Dryden KA, Makhov AM, Conway JF, Pizzorno MC, Hafenstein S.

J Virol. 2017 Jan 3;91(2). pii: e01795-16. doi: 10.1128/JVI.01795-16. Print 2017 Jan 15.

15.

The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs.

Lee H, Shingler KL, Organtini LJ, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

Sci Adv. 2016 Aug 24;2(8):e1501929. doi: 10.1126/sciadv.1501929. eCollection 2016 Aug.

16.

Near-Atomic Resolution Structure of a Highly Neutralizing Fab Bound to Canine Parvovirus.

Organtini LJ, Lee H, Iketani S, Huang K, Ashley RE, Makhov AM, Conway JF, Parrish CR, Hafenstein S.

J Virol. 2016 Oct 14;90(21):9733-9742. doi: 10.1128/JVI.01112-16. Print 2016 Nov 1.

17.

Transmission electron microscopy for the evaluation and optimization of crystal growth.

Stevenson HP, Lin G, Barnes CO, Sutkeviciute I, Krzysiak T, Weiss SC, Reynolds S, Wu Y, Nagarajan V, Makhov AM, Lawrence R, Lamm E, Clark L, Gardella TJ, Hogue BG, Ogata CM, Ahn J, Gronenborn AM, Conway JF, Vilardaga JP, Cohen AE, Calero G.

Acta Crystallogr D Struct Biol. 2016 May;72(Pt 5):603-15. doi: 10.1107/S2059798316001546. Epub 2016 Apr 26.

18.

Extensive subunit contacts underpin herpesvirus capsid stability and interior-to-exterior allostery.

Huet A, Makhov AM, Huffman JB, Vos M, Homa FL, Conway JF.

Nat Struct Mol Biol. 2016 Jun;23(6):531-9. doi: 10.1038/nsmb.3212. Epub 2016 Apr 25.

19.

Correct Assembly of the Bacteriophage T5 Procapsid Requires Both the Maturation Protease and the Portal Complex.

Huet A, Duda RL, Hendrix RW, Boulanger P, Conway JF.

J Mol Biol. 2016 Jan 16;428(1):165-181. doi: 10.1016/j.jmb.2015.11.019. Epub 2015 Nov 23.

20.

Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization.

Guan J, Bywaters SM, Brendle SA, Lee H, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

Virology. 2015 Sep;483:253-63. doi: 10.1016/j.virol.2015.04.016. Epub 2015 May 19.

21.

Ff-nano, short functionalized nanorods derived from Ff (f1, fd, or M13) filamentous bacteriophage.

Sattar S, Bennett NJ, Wen WX, Guthrie JM, Blackwell LF, Conway JF, Rakonjac J.

Front Microbiol. 2015 Apr 20;6:316. doi: 10.3389/fmicb.2015.00316. eCollection 2015.

22.

The A, B, Cs of herpesvirus capsids.

Tandon R, Mocarski ES, Conway JF.

Viruses. 2015 Feb 26;7(3):899-914. doi: 10.3390/v7030899. Review.

23.

The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.

Shingler KL, Cifuente JO, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

J Virol. 2015 Feb;89(3):1900-8. doi: 10.1128/JVI.03098-14. Epub 2014 Nov 26.

24.

A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment.

Lee H, Brendle SA, Bywaters SM, Guan J, Ashley RE, Yoder JD, Makhov AM, Conway JF, Christensen ND, Hafenstein S.

J Virol. 2015 Jan 15;89(2):1428-38. doi: 10.1128/JVI.02898-14. Epub 2014 Nov 12.

25.

Metastable intermediates as stepping stones on the maturation pathways of viral capsids.

Cardone G, Duda RL, Cheng N, You L, Conway JF, Hendrix RW, Steven AC.

MBio. 2014 Nov 11;5(6):e02067. doi: 10.1128/mBio.02067-14.

26.

The putative herpes simplex virus 1 chaperone protein UL32 modulates disulfide bond formation during infection.

Albright BS, Kosinski A, Szczepaniak R, Cook EA, Stow ND, Conway JF, Weller SK.

J Virol. 2015 Jan;89(1):443-53. doi: 10.1128/JVI.01913-14. Epub 2014 Oct 15.

27.

Inducible polymerization and two-dimensional assembly of the repeats-in-toxin (RTX) domain from the Pseudomonas aeruginosa alkaline protease.

Zhang L, Franks J, Stolz DB, Conway JF, Thibodeau PH.

Biochemistry. 2014 Oct 21;53(41):6452-62. doi: 10.1021/bi5007546. Epub 2014 Oct 3.

28.

Transmission electron microscopy as a tool for nanocrystal characterization pre- and post-injector.

Stevenson HP, DePonte DP, Makhov AM, Conway JF, Zeldin OB, Boutet S, Calero G, Cohen AE.

Philos Trans R Soc Lond B Biol Sci. 2014 Jul 17;369(1647):20130322. doi: 10.1098/rstb.2013.0322.

29.

Use of transmission electron microscopy to identify nanocrystals of challenging protein targets.

Stevenson HP, Makhov AM, Calero M, Edwards AL, Zeldin OB, Mathews II, Lin G, Barnes CO, Santamaria H, Ross TM, Soltis SM, Khosla C, Nagarajan V, Conway JF, Cohen AE, Calero G.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8470-5. doi: 10.1073/pnas.1400240111. Epub 2014 May 28.

30.

Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle.

Organtini LJ, Makhov AM, Conway JF, Hafenstein S, Carson SD.

J Virol. 2014 May;88(10):5755-65. doi: 10.1128/JVI.00299-14. Epub 2014 Mar 12.

31.

A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.

Lee H, Cifuente JO, Ashley RE, Conway JF, Makhov AM, Tano Y, Shimizu H, Nishimura Y, Hafenstein S.

J Virol. 2013 Nov;87(21):11363-70. doi: 10.1128/JVI.01926-13. Epub 2013 Aug 14.

32.

Cluster J mycobacteriophages: intron splicing in capsid and tail genes.

Pope WH, Jacobs-Sera D, Best AA, Broussard GW, Connerly PL, Dedrick RM, Kremer TA, Offner S, Ogiefo AH, Pizzorno MC, Rockenbach K, Russell DA, Stowe EL, Stukey J, Thibault SA, Conway JF, Hendrix RW, Hatfull GF.

PLoS One. 2013 Jul 9;8(7):e69273. doi: 10.1371/journal.pone.0069273. Print 2013.

33.

Structure of the pseudorabies virus capsid: comparison with herpes simplex virus type 1 and differential binding of essential minor proteins.

Homa FL, Huffman JB, Toropova K, Lopez HR, Makhov AM, Conway JF.

J Mol Biol. 2013 Sep 23;425(18):3415-28. doi: 10.1016/j.jmb.2013.06.034. Epub 2013 Jul 1.

34.

CryoTEM study of effects of phosphorylation on the hierarchical assembly of porcine amelogenin and its regulation of mineralization in vitro.

Fang PA, Margolis HC, Conway JF, Simmer JP, Beniash E.

J Struct Biol. 2013 Aug;183(2):250-7. doi: 10.1016/j.jsb.2013.05.011. Epub 2013 May 23.

35.

Structures of the procapsid and mature virion of enterovirus 71 strain 1095.

Cifuente JO, Lee H, Yoder JD, Shingler KL, Carnegie MS, Yoder JL, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

J Virol. 2013 Jul;87(13):7637-45. doi: 10.1128/JVI.03519-12. Epub 2013 May 1.

36.

The enterovirus 71 A-particle forms a gateway to allow genome release: a cryoEM study of picornavirus uncoating.

Shingler KL, Yoder JL, Carnegie MS, Ashley RE, Makhov AM, Conway JF, Hafenstein S.

PLoS Pathog. 2013 Mar;9(3):e1003240. doi: 10.1371/journal.ppat.1003240. Epub 2013 Mar 21. Erratum in: PLoS Pathog. 2013 Sep;9(9). doi: 10.1371/annotation/e92d19e0-996a-4bfa-afdd-20dce770ed75.

37.

A two-state cooperative expansion converts the procapsid shell of bacteriophage T5 into a highly stable capsid isomorphous to the final virion head.

Preux O, Durand D, Huet A, Conway JF, Bertin A, Boulogne C, Drouin-Wahbi J, Trévarin D, Pérez J, Vachette P, Boulanger P.

J Mol Biol. 2013 Jun 12;425(11):1999-2014. doi: 10.1016/j.jmb.2013.03.002. Epub 2013 Mar 13.

PMID:
23500494
38.

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.

Yeh JI, Levine AS, Du S, Chinte U, Ghodke H, Wang H, Shi H, Hsieh CL, Conway JF, Van Houten B, Rapić-Otrin V.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2737-46. doi: 10.1073/pnas.1110067109. Epub 2012 Jul 20.

39.

Calcium-induced folding and stabilization of the Pseudomonas aeruginosa alkaline protease.

Zhang L, Conway JF, Thibodeau PH.

J Biol Chem. 2012 Feb 3;287(6):4311-22. doi: 10.1074/jbc.M111.310300. Epub 2011 Dec 14.

40.

Determining frameworks for interprofessional education and core competencies through collaborative consultancy: the CARE experience.

Conway JF, Little P, McMillan M, Fitzgerald M.

Contemp Nurse. 2011 Apr-Jun;38(1-2):160-70. doi: 10.5172/conu.2011.38.1-2.160.

PMID:
21854247
41.

Hierarchical self-assembly of amelogenin and the regulation of biomineralization at the nanoscale.

Fang PA, Conway JF, Margolis HC, Simmer JP, Beniash E.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14097-102. doi: 10.1073/pnas.1106228108. Epub 2011 Aug 8.

42.

Disulfide bond formation contributes to herpes simplex virus capsid stability and retention of pentons.

Szczepaniak R, Nellissery J, Jadwin JA, Makhov AM, Kosinski A, Conway JF, Weller SK.

J Virol. 2011 Sep;85(17):8625-34. doi: 10.1128/JVI.00214-11. Epub 2011 Jun 22.

43.

The herpes simplex virus 1 UL17 protein is the second constituent of the capsid vertex-specific component required for DNA packaging and retention.

Toropova K, Huffman JB, Homa FL, Conway JF.

J Virol. 2011 Aug;85(15):7513-22. doi: 10.1128/JVI.00837-11. Epub 2011 Jun 1.

44.

Cryogenic transmission electron microscopy study of amelogenin self-assembly at different pH.

Fang PA, Margolis HC, Conway JF, Simmer JP, Dickinson GH, Beniash E.

Cells Tissues Organs. 2011;194(2-4):166-70. doi: 10.1159/000324250. Epub 2011 May 20.

45.

Role of the propeptide in controlling conformation and assembly state of hepatitis B virus e-antigen.

Watts NR, Conway JF, Cheng N, Stahl SJ, Steven AC, Wingfield PT.

J Mol Biol. 2011 Jun 3;409(2):202-13. doi: 10.1016/j.jmb.2011.03.049. Epub 2011 Apr 2.

46.

Residues of the UL25 protein of herpes simplex virus that are required for its stable interaction with capsids.

Cockrell SK, Huffman JB, Toropova K, Conway JF, Homa FL.

J Virol. 2011 May;85(10):4875-87. doi: 10.1128/JVI.00242-11. Epub 2011 Mar 16.

47.

Sar1 assembly regulates membrane constriction and ER export.

Long KR, Yamamoto Y, Baker AL, Watkins SC, Coyne CB, Conway JF, Aridor M.

J Cell Biol. 2010 Jul 12;190(1):115-28. doi: 10.1083/jcb.201004132.

48.

In vitro assembly of the T=13 procapsid of bacteriophage T5 with its scaffolding domain.

Huet A, Conway JF, Letellier L, Boulanger P.

J Virol. 2010 Sep;84(18):9350-8. doi: 10.1128/JVI.00942-10. Epub 2010 Jun 23.

49.

The tripartite capsid gene of Salmonella phage Gifsy-2 yields a capsid assembly pathway engaging features from HK97 and lambda.

Effantin G, Figueroa-Bossi N, Schoehn G, Bossi L, Conway JF.

Virology. 2010 Jul 5;402(2):355-65. doi: 10.1016/j.virol.2010.03.041. Epub 2010 Apr 28.

50.

Labeling and localization of the herpes simplex virus capsid protein UL25 and its interaction with the two triplexes closest to the penton.

Conway JF, Cockrell SK, Copeland AM, Newcomb WW, Brown JC, Homa FL.

J Mol Biol. 2010 Mar 26;397(2):575-86. doi: 10.1016/j.jmb.2010.01.043. Epub 2010 Jan 25.

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