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Measuring Uncertainty Intolerance in Surgical Residents Using Standardized Assessments.

Ying LD, Harrington A, Assi R, Thiessen C, Contessa J, Hubbard M, Yoo P, Nadzam G.

J Surg Res. 2019 Aug 13;245:145-152. doi: 10.1016/j.jss.2019.07.035. [Epub ahead of print]


Neuregulin Signaling is a Mechanism of Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma.

Baro M, Lopez Sambrooks C, Burtness BA, Lemmon MA, Contessa JN.

Mol Cancer Ther. 2019 Aug 6. pii: molcanther.0163.2019. doi: 10.1158/1535-7163.MCT-19-0163. [Epub ahead of print]


Defining an Intermediate-risk Group for Low-grade Glioma: A National Cancer Database Analysis.

Jairam V, Kann BH, Park HS, Miccio JA, Beckta JM, Yu JB, Prabhu RS, Gao SJ, Mehta MP, Curran WJ, Bindra RS, Contessa JN, Patel KR.

Anticancer Res. 2019 Jun;39(6):2911-2918. doi: 10.21873/anticanres.13420.


Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing.

Klaver E, Zhao P, May M, Flanagan-Steet H, Freeze HH, Gilmore R, Wells L, Contessa J, Steet R.

Dis Model Mech. 2019 Jun 5;12(6). pii: dmm039602. doi: 10.1242/dmm.039602.


Initial SRS for Patients With 5 to 15 Brain Metastases: Results of a Multi-Institutional Experience.

Hughes RT, Masters AH, McTyre ER, Farris MK, Chung C, Page BR, Kleinberg LR, Hepel J, Contessa JN, Chiang V, Ruiz J, Watabe K, Su J, Fiveash JB, Braunstein S, Chao S, Attia A, Ayala-Peacock DN, Chan MD.

Int J Radiat Oncol Biol Phys. 2019 Aug 1;104(5):1091-1098. doi: 10.1016/j.ijrobp.2019.03.052. Epub 2019 Apr 6.


Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction.

Lu H, Cherepanova NA, Gilmore R, Contessa JN, Lehrman MA.

FASEB J. 2019 Jun;33(6):6801-6812. doi: 10.1096/fj.201802044RR. Epub 2019 Feb 27.


Case report on the multiple pathways to posttraumatic stress disorder following suicide.

Padoan CS, Cardoso TA, Martini M, Farias CA, Contessa JC, Magalhães PVDS.

Death Stud. 2019 Feb 12:1-8. doi: 10.1080/07481187.2019.1572675. [Epub ahead of print]


Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas.

Yeboa DN, Yu JB, Liao E, Huse J, Penas-Prado M, Kann BH, Sulman E, Grosshans D, Contessa J.

Clin Transl Radiat Oncol. 2018 Dec 31;15:46-52. doi: 10.1016/j.ctro.2018.12.003. eCollection 2019 Feb.


Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors.

Rinis N, Golden JE, Marceau CD, Carette JE, Van Zandt MC, Gilmore R, Contessa JN.

Cell Chem Biol. 2018 Oct 18;25(10):1231-1241.e4. doi: 10.1016/j.chembiol.2018.07.005. Epub 2018 Aug 2.


Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors.

Lopez Sambrooks C, Baro M, Quijano A, Narayan A, Cui W, Greninger P, Egan R, Patel A, Benes CH, Saltzman WM, Contessa JN.

Cancer Res. 2018 Sep 1;78(17):5094-5106. doi: 10.1158/0008-5472.CAN-18-0505. Epub 2018 Jul 19.


Oligosaccharyltransferase Inhibition Reduces Receptor Tyrosine Kinase Activation and Enhances Glioma Radiosensitivity.

Baro M, Lopez Sambrooks C, Quijano A, Saltzman WM, Contessa J.

Clin Cancer Res. 2019 Jan 15;25(2):784-795. doi: 10.1158/1078-0432.CCR-18-0792. Epub 2018 Jul 2.


Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology.

Bristow RG, Alexander B, Baumann M, Bratman SV, Brown JM, Camphausen K, Choyke P, Citrin D, Contessa JN, Dicker A, Kirsch DG, Krause M, Le QT, Milosevic M, Morris ZS, Sarkaria JN, Sondel PM, Tran PT, Wilson GD, Willers H, Wong RKS, Harari PM.

Lancet Oncol. 2018 May;19(5):e240-e251. doi: 10.1016/S1470-2045(18)30096-2. Review.


MPDU1 regulates CEACAM1 and cell adhesion in vitro and in vivo.

Bennett DC, Cazet A, Charest J, Contessa JN.

Glycoconj J. 2018 Jun;35(3):265-274. doi: 10.1007/s10719-018-9819-6. Epub 2018 Apr 18.


CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma.

Chen WS, Bindra RS, Mo A, Hayman T, Husain Z, Contessa JN, Gaffney SG, Townsend JP, Yu JB.

Front Oncol. 2018 Apr 4;8:95. doi: 10.3389/fonc.2018.00095. eCollection 2018.


Upfront surgery versus definitive chemoradiotherapy in patients with human Papillomavirus-associated oropharyngeal squamous cell cancer.

Kelly JR, Park HS, An Y, Yarbrough WG, Contessa JN, Decker R, Mehra S, Judson BL, Burtness B, Husain Z.

Oral Oncol. 2018 Apr;79:64-70. doi: 10.1016/j.oraloncology.2018.02.017. Epub 2018 Mar 8.


A Small-Molecule Oligosaccharyltransferase Inhibitor with Pan-flaviviral Activity.

Puschnik AS, Marceau CD, Ooi YS, Majzoub K, Rinis N, Contessa JN, Carette JE.

Cell Rep. 2017 Dec 12;21(11):3032-3039. doi: 10.1016/j.celrep.2017.11.054.


Multi-institutional competing risks analysis of distant brain failure and salvage patterns after upfront radiosurgery without whole brain radiotherapy for brain metastasis.

McTyre E, Ayala-Peacock D, Contessa J, Corso C, Chiang V, Chung C, Fiveash J, Ahluwalia M, Kotecha R, Chao S, Attia A, Henson A, Hepel J, Braunstein S, Chan M.

Ann Oncol. 2018 Feb 1;29(2):497-503. doi: 10.1093/annonc/mdx740.


Angiotensin receptor blockade: a novel approach for symptomatic radiation necrosis after stereotactic radiosurgery.

Chowdhary M, Okwan-Duodu D, Switchenko JM, Press RH, Jhaveri J, Buchwald ZS, Zhong J, Chapman BV, Bindra RS, Contessa JN, Park HS, Yu JB, Decker RH, Olson JJ, Oyesiku NM, Abrams RA, Shu HG, Curran WJ Jr, Crocker IR, Patel KR.

J Neurooncol. 2018 Jan;136(2):289-298. doi: 10.1007/s11060-017-2652-0. Epub 2017 Nov 9.


Patterns of care and outcomes for use of concurrent chemoradiotherapy over radiotherapy alone for anaplastic gliomas.

Yeboa DN, Rutter CE, Park HS, Lester-Coll NH, Corso CD, Mancini BR, Bindra RS, Contessa J, Yu JB.

Radiother Oncol. 2017 Nov;125(2):258-265. doi: 10.1016/j.radonc.2017.09.027. Epub 2017 Oct 17.


Prediction of new brain metastases after radiosurgery: validation and analysis of performance of a multi-institutional nomogram.

Ayala-Peacock DN, Attia A, Braunstein SE, Ahluwalia MS, Hepel J, Chung C, Contessa J, McTyre E, Peiffer AM, Lucas JT Jr, Isom S, Pajewski NM, Kotecha R, Stavas MJ, Page BR, Kleinberg L, Shen C, Taylor RB, Onyeuku NE, Hyde AT, Gorovets D, Chao ST, Corso C, Ruiz J, Watabe K, Tatter SB, Zadeh G, Chiang VLS, Fiveash JB, Chan MD.

J Neurooncol. 2017 Nov;135(2):403-411. doi: 10.1007/s11060-017-2588-4. Epub 2017 Aug 21.


The prognostic value of extranodal extension in human papillomavirus-associated oropharyngeal squamous cell carcinoma.

An Y, Park HS, Kelly JR, Stahl JM, Yarbrough WG, Burtness BA, Contessa JN, Decker RH, Koshy M, Husain ZA.

Cancer. 2017 Jul 15;123(14):2762-2772. doi: 10.1002/cncr.30598. Epub 2017 Mar 21.


A multi species evaluation of the radiation dosimetry of [11C]erlotinib, the radiolabeled analog of a clinically utilized tyrosine kinase inhibitor.

Petrulli JR, Hansen SB, Abourbeh G, Yaqub M, Bahce I, Holden D, Huang Y, Nabulsi NB, Contessa JN, Mishani E, Lammertsma AA, Morris ED.

Nucl Med Biol. 2017 Apr;47:56-61. doi: 10.1016/j.nucmedbio.2016.12.009. Epub 2017 Jan 2.


Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naïve Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis.

Magnuson WJ, Lester-Coll NH, Wu AJ, Yang TJ, Lockney NA, Gerber NK, Beal K, Amini A, Patil T, Kavanagh BD, Camidge DR, Braunstein SE, Boreta LC, Balasubramanian SK, Ahluwalia MS, Rana NG, Attia A, Gettinger SN, Contessa JN, Yu JB, Chiang VL.

J Clin Oncol. 2017 Apr 1;35(10):1070-1077. doi: 10.1200/JCO.2016.69.7144. Epub 2017 Jan 23.


Comparison of Survival Outcomes Among Human Papillomavirus-Negative cT1-2 N1-2b Patients With Oropharyngeal Squamous Cell Cancer Treated With Upfront Surgery vs Definitive Chemoradiation Therapy: An Observational Study.

Kelly JR, Park HS, An Y, Contessa JN, Yarbrough WG, Burtness BA, Decker R, Husain Z.

JAMA Oncol. 2017 Aug 1;3(8):1107-1111. doi: 10.1001/jamaoncol.2016.5769.


Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA).

Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP.

JAMA Oncol. 2017 Jun 1;3(6):827-831. doi: 10.1001/jamaoncol.2016.3834.


Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.

Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN.

Nat Chem Biol. 2016 Dec;12(12):1023-1030. doi: 10.1038/nchembio.2194. Epub 2016 Oct 3.


The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases.

Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP.

Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):406-413. doi: 10.1016/j.ijrobp.2016.06.006. Epub 2016 Jun 14.


Reply to M.S. Copur et al and to M.C. Chamberlain.

Contessa JN, Johung KL, Goldberg S, Chiang VL.

J Clin Oncol. 2016 Jul 1;34(19):2316-7. doi: 10.1200/JCO.2016.67.2816. Epub 2016 Apr 25. No abstract available.


Demonstration of differential radiosensitivity based upon mutation profile in metastatic melanoma treated with stereotactic radiosurgery.

Rutter CE, Johung KL, Yao X, Lu AY, Jilaveanu LB, Yu JB, Contessa JN, Kluger HM, Chiang VLS, Bindra RS.

J Radiosurg SBRT. 2016;4(2):97-106.


A contemporary dose selection algorithm for stereotactic radiosurgery in the treatment of brain metastases - An initial report.

Colaco RJ, Yu JB, Bond JS, Bindra RS, Contessa JN, Knisely JPS, Chiang VL.

J Radiosurg SBRT. 2016;4(1):43-52.


Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastasis.

Johung KL, Yeh N, Desai NB, Williams TM, Lautenschlaeger T, Arvold ND, Ning MS, Attia A, Lovly CM, Goldberg S, Beal K, Yu JB, Kavanagh BD, Chiang VL, Camidge DR, Contessa JN.

J Clin Oncol. 2016 Jan 10;34(2):123-9. doi: 10.1200/JCO.2015.62.0138. Epub 2015 Oct 5.


Lung Cancer Brain Metastases.

Goldberg SB, Contessa JN, Omay SB, Chiang V.

Cancer J. 2015 Sep-Oct;21(5):398-403. doi: 10.1097/PPO.0000000000000146. Review.


Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity.

Cazet A, Charest J, Bennett DC, Sambrooks CL, Contessa JN.

PLoS One. 2014 Oct 14;9(10):e110345. doi: 10.1371/journal.pone.0110345. eCollection 2014.


Quantitative analysis of [11C]-erlotinib PET demonstrates specific binding for activating mutations of the EGFR kinase domain.

Petrulli JR, Sullivan JM, Zheng MQ, Bennett DC, Charest J, Huang Y, Morris ED, Contessa JN.

Neoplasia. 2013 Dec;15(12):1347-53.


The influence of surgeon personality factors on risk tolerance: a pilot study.

Contessa J, Suarez L, Kyriakides T, Nadzam G.

J Surg Educ. 2013 Nov-Dec;70(6):806-12. doi: 10.1016/j.jsurg.2013.07.014. Review.


A clinical model for identifying radiosensitive tumor genotypes in non-small cell lung cancer.

Johung KL, Yao X, Li F, Yu JB, Gettinger SN, Goldberg S, Decker RH, Hess JA, Chiang VL, Contessa JN.

Clin Cancer Res. 2013 Oct 1;19(19):5523-32. doi: 10.1158/1078-0432.CCR-13-0836. Epub 2013 Jul 29.


High-throughput screening identifies aclacinomycin as a radiosensitizer of EGFR-mutant non-small cell lung cancer.

Bennett DC, Charest J, Sebolt K, Lehrman M, Rehemtulla A, Contessa JN.

Transl Oncol. 2013 Jun 1;6(3):382-91. Print 2013 Jun.


Role of excision repair cross-complementation 1 expression as a prognostic marker for response to radiotherapy in early-stage laryngeal cancer.

Johung K, Rewari A, Wu H, Judson B, Contessa JN, Haffty BG, Decker RH.

Head Neck. 2013 Jun;35(6):852-7. doi: 10.1002/hed.23041. Epub 2012 Jun 28.


Can moral reasoning predict general surgery residents' clinical competence?

Contessa J, Kyriakides T, Kim D.

J Surg Educ. 2012 Jan-Feb;69(1):17-22. doi: 10.1016/j.jsurg.2011.06.014. Epub 2011 Aug 27.


Molecular imaging of epidermal growth factor receptor kinase activity.

Khan AP, Contessa JN, Nyati MK, Ross BD, Rehemtulla A.

Anal Biochem. 2011 Oct 1;417(1):57-64. doi: 10.1016/j.ab.2011.05.040. Epub 2011 May 30.


The impact of laparoscopy on the volume of open cases in general surgery training.

Alkhoury F, Martin JT, Contessa J, Zuckerman R, Nadzam G.

J Surg Educ. 2010 Sep-Oct;67(5):316-9. doi: 10.1016/j.jsurg.2010.08.001.


Molecular imaging of N-linked glycosylation suggests glycan biosynthesis is a novel target for cancer therapy.

Contessa JN, Bhojani MS, Freeze HH, Ross BD, Rehemtulla A, Lawrence TS.

Clin Cancer Res. 2010 Jun 15;16(12):3205-14. doi: 10.1158/1078-0432.CCR-09-3331. Epub 2010 Apr 22.


Radiotherapy for pancreatic neuroendocrine tumors.

Contessa JN, Griffith KA, Wolff E, Ensminger W, Zalupski M, Lawrence TS, Ben-Josef E.

Int J Radiat Oncol Biol Phys. 2009 Nov 15;75(4):1196-200. doi: 10.1016/j.ijrobp.2008.12.044. Epub 2009 Mar 26.


Inhibition of N-linked glycosylation disrupts receptor tyrosine kinase signaling in tumor cells.

Contessa JN, Bhojani MS, Freeze HH, Rehemtulla A, Lawrence TS.

Cancer Res. 2008 May 15;68(10):3803-9. doi: 10.1158/0008-5472.CAN-07-6389.


Revoking the privilege: targeting HER2 in the central nervous system.

Contessa JN, Hamstra DA.

Mol Pharmacol. 2008 Feb;73(2):271-3. Epub 2007 Nov 2. Review.


Using ErbB2-negative status to direct therapy in locally advanced breast cancer.

Spalding AC, Contessa JN.

Cancer Biol Ther. 2007 Mar;6(3):463-4. Epub 2007 Mar 20. No abstract available.


Superior mesenteric artery syndrome in patients undergoing gastric bypass surgery.

Abou-Nukta F, Valin E, Rao S, Kim D, Contessa J, Reinhold R.

Surg Obes Relat Dis. 2005 Mar-Apr;1(2):95-8. No abstract available.


ErbB receptor tyrosine kinase network inhibition radiosensitizes carcinoma cells.

Contessa JN, Abell A, Valerie K, Lin PS, Schmidt-Ullrich RK.

Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):851-8.


Targeted radiation for melanoma: alpha therapy prepares for a beta test.

Contessa JN, Roberson PL.

Cancer Biol Ther. 2006 Jan;5(1):118-9. Epub 2006 Jan 11. No abstract available.


Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation.

Contessa JN, Abell A, Mikkelsen RB, Valerie K, Schmidt-Ullrich RK.

Breast Cancer Res Treat. 2006 Jan;95(1):17-27.

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