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Items: 1 to 50 of 251

1.

Microvesicle-mediated delivery of minicircle DNA results in effective gene-directed enzyme prodrug cancer therapy.

Kanada M, Kim BD, Hardy JW, Ronald JA, Bachmann MH, Bernard MP, Perez GI, Zarea AA, Ge TJ, Withrow A, Ibrahim SA, Toomajian V, Gambhir SS, Paulmurugan R, Contag CH.

Mol Cancer Ther. 2019 Aug 26. pii: molcanther.0299.2019. doi: 10.1158/1535-7163.MCT-19-0299. [Epub ahead of print]

PMID:
31451563
2.

Tunable structured illumination light sheet microscopy for background rejection and imaging depth in minimally processed tissues.

Landry JR, Itoh R, Li JM, Hamann SS, Mandella M, Contag CH, Solgaard O.

J Biomed Opt. 2019 Apr;24(4):1-6. doi: 10.1117/1.JBO.24.4.046501.

3.

Detection of Premalignant Gastrointestinal Lesions Using Surface-Enhanced Resonance Raman Scattering-Nanoparticle Endoscopy.

Harmsen S, Rogalla S, Huang R, Spaliviero M, Neuschmelting V, Hayakawa Y, Lee Y, Tailor Y, Toledo-Crow R, Kang JW, Samii JM, Karabeber H, Davis RM, White JR, van de Rijn M, Gambhir SS, Contag CH, Wang TC, Kircher MF.

ACS Nano. 2019 Feb 26;13(2):1354-1364. doi: 10.1021/acsnano.8b06808. Epub 2019 Feb 4.

4.

A Dual-Modality Hybrid Imaging System Harnesses Radioluminescence and Sound to Reveal Molecular Pathology of Atherosclerotic Plaques.

Zaman RT, Yousefi S, Long SR, Saito T, Mandella M, Qiu Z, Chen R, Contag CH, Gambhir SS, Chin FT, Khuri-Yakub BT, McConnell MV, Shung KK, Xing L.

Sci Rep. 2018 Jun 12;8(1):8992. doi: 10.1038/s41598-018-26696-8.

5.

Functional DNA Delivery Enabled by Lipid-Modified Charge-Altering Releasable Transporters (CARTs).

Benner NL, Near KE, Bachmann MH, Contag CH, Waymouth RM, Wender PA.

Biomacromolecules. 2018 Jul 9;19(7):2812-2824. doi: 10.1021/acs.biomac.8b00401. Epub 2018 May 11.

6.

Magnetic particle imaging of islet transplantation in the liver and under the kidney capsule in mouse models.

Wang P, Goodwill PW, Pandit P, Gaudet J, Ross A, Wang J, Yu E, Hensley DW, Doyle TC, Contag CH, Conolly S, Moore A.

Quant Imaging Med Surg. 2018 Mar;8(2):114-122. doi: 10.21037/qims.2018.02.06.

7.

Automated Cell Segmentation for Quantitative Phase Microscopy.

Loewke NO, Pai S, Cordeiro C, Black D, King BL, Contag CH, Chen B, Baer TM, Solgaard O.

IEEE Trans Med Imaging. 2018 Apr;37(4):929-940. doi: 10.1109/TMI.2017.2775604.

8.

Intracellular biomass flocculation as a key mechanism of rapid bacterial killing by cationic, amphipathic antimicrobial peptides and peptoids.

Chongsiriwatana NP, Lin JS, Kapoor R, Wetzler M, Rea JAC, Didwania MK, Contag CH, Barron AE.

Sci Rep. 2017 Dec 1;7(1):16718. doi: 10.1038/s41598-017-16180-0.

9.

Local estrogen axis in the human bone microenvironment regulates estrogen receptor-positive breast cancer cells.

Amanatullah DF, Tamaresis JS, Chu P, Bachmann MH, Hoang NM, Collyar D, Mayer AT, West RB, Maloney WJ, Contag CH, King BL.

Breast Cancer Res. 2017 Nov 15;19(1):121. doi: 10.1186/s13058-017-0910-x.

10.

The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice.

Reber LL, Starkl P, Balbino B, Sibilano R, Gaudenzio N, Rogalla S, Sensarn S, Kang D, Raghu H, Sokolove J, Robinson WH, Contag CH, Tsai M, Galli SJ.

PLoS One. 2017 Oct 5;12(10):e0185704. doi: 10.1371/journal.pone.0185704. eCollection 2017.

11.

Cell Labeling with Magneto-Endosymbionts and the Dissection of the Subcellular Location, Fate, and Host Cell Interactions.

Lee KR, Wakeel A, Chakraborty P, Foote CS, Kajiura L, Barrozo JC, Chan AC, Bazarov AV, Spitler R, Kutny PM, Denegre JM, Taft RA, Seemann J, Rice BW, Contag CH, Rutt BK, Bell CB 3rd.

Mol Imaging Biol. 2018 Feb;20(1):55-64. doi: 10.1007/s11307-017-1094-6.

12.

Characterization of Magneto-Endosymbionts as MRI Cell Labeling and Tracking Agents.

Brewer KD, Spitler R, Lee KR, Chan AC, Barrozo JC, Wakeel A, Foote CS, Machtaler S, Rioux J, Willmann JK, Chakraborty P, Rice BW, Contag CH, Bell CB 3rd, Rutt BK.

Mol Imaging Biol. 2018 Feb;20(1):65-73. doi: 10.1007/s11307-017-1093-7.

13.

Specific Imaging of Bacterial Infection Using 6″-18F-Fluoromaltotriose: A Second-Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria.

Gowrishankar G, Hardy J, Wardak M, Namavari M, Reeves RE, Neofytou E, Srinivasan A, Wu JC, Contag CH, Gambhir SS.

J Nucl Med. 2017 Oct;58(10):1679-1684. doi: 10.2967/jnumed.117.191452. Epub 2017 May 10.

14.

Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection.

Tummers WS, Warram JM, Tipirneni KE, Fengler J, Jacobs P, Shankar L, Henderson L, Ballard B, Pfefer TJ, Pogue BW, Weichert JP, Bouvet M, Sorger J, Contag CH, Frangioni JV, Tweedle MF, Basilion JP, Gambhir SS, Rosenthal EL.

Cancer Res. 2017 May 1;77(9):2197-2206. doi: 10.1158/0008-5472.CAN-16-3217. Epub 2017 Apr 20. Erratum in: Cancer Res. 2018 Feb 15;78(4):1123.

15.

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.

Reber LL, Gillis CM, Starkl P, Jönsson F, Sibilano R, Marichal T, Gaudenzio N, Bérard M, Rogalla S, Contag CH, Bruhns P, Galli SJ.

J Exp Med. 2017 May 1;214(5):1249-1258. doi: 10.1084/jem.20161238. Epub 2017 Apr 6.

16.

Imaging of Tumor-Associated Macrophages in a Transgenic Mouse Model of Orthotopic Ovarian Cancer.

He H, Chiu AC, Kanada M, Schaar BT, Krishnan V, Contag CH, Dorigo O.

Mol Imaging Biol. 2017 Oct;19(5):694-702. doi: 10.1007/s11307-017-1061-2.

PMID:
28233218
17.

Targeted Nanomeetings within a Larger Delivery Congress.

Contag CH.

Mol Imaging Biol. 2017 Jun;19(3):323-324. doi: 10.1007/s11307-017-1067-9. No abstract available.

PMID:
28224324
18.

Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals.

McKinlay CJ, Vargas JR, Blake TR, Hardy JW, Kanada M, Contag CH, Wender PA, Waymouth RM.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E448-E456. doi: 10.1073/pnas.1614193114. Epub 2017 Jan 9.

19.

A Clinical Wide-Field Fluorescence Endoscopic Device for Molecular Imaging Demonstrating Cathepsin Protease Activity in Colon Cancer.

Sensarn S, Zavaleta CL, Segal E, Rogalla S, Lee W, Gambhir SS, Bogyo M, Contag CH.

Mol Imaging Biol. 2016 Dec;18(6):820-829.

20.

World Molecular Imaging Congress 2016: Imaging Biology-Improving Therapy.

Kiessling F, Contag CH.

Mol Imaging Biol. 2016 Jun;18(3):313-4. doi: 10.1007/s11307-016-0958-5. No abstract available.

PMID:
27080321
21.

A role of the adaptive immune system in glucose homeostasis.

Bronsart LL, Contag CH.

BMJ Open Diabetes Res Care. 2016 Feb 15;4(1):e000136. doi: 10.1136/bmjdrc-2015-000136. eCollection 2016.

22.

More Chemistry Is Needed for Molecular Imaging.

Rao J, Contag CH.

Bioconjug Chem. 2016 Feb 17;27(2):265-6. doi: 10.1021/acs.bioconjchem.6b00056. No abstract available.

PMID:
26883480
23.

Signaling by Extracellular Vesicles Advances Cancer Hallmarks.

Kanada M, Bachmann MH, Contag CH.

Trends Cancer. 2016 Feb;2(2):84-94. doi: 10.1016/j.trecan.2015.12.005. Epub 2016 Jan 22. Review.

PMID:
28741553
24.

Chemiluminescence Imaging of Superoxide Anion Detects Beta-Cell Function and Mass.

Bronsart LL, Stokes C, Contag CH.

PLoS One. 2016 Jan 11;11(1):e0146601. doi: 10.1371/journal.pone.0146601. eCollection 2016.

25.

Breast Cancer Cell Colonization of the Human Bone Marrow Adipose Tissue Niche.

Templeton ZS, Lie WR, Wang W, Rosenberg-Hasson Y, Alluri RV, Tamaresis JS, Bachmann MH, Lee K, Maloney WJ, Contag CH, King BL.

Neoplasia. 2015 Dec;17(12):849-861. doi: 10.1016/j.neo.2015.11.005.

26.

Imaging Functional Nucleic Acid Delivery to Skin.

Kaspar RL, Hickerson RP, González-González E, Flores MA, Speaker TP, Rogers FA, Milstone LM, Contag CH.

Methods Mol Biol. 2016;1372:1-24. doi: 10.1007/978-1-4939-3148-4_1.

PMID:
26530911
27.

Multimodality Imaging of Cancer Superoxide Anion Using the Small Molecule Coelenterazine.

Bronsart LL, Stokes C, Contag CH.

Mol Imaging Biol. 2016 Apr;18(2):166-71. doi: 10.1007/s11307-015-0896-7.

PMID:
26420297
28.

Non-Invasive Intravital Imaging of siRNA-Mediated Mutant Keratin Gene Repression in Skin.

Hickerson RP, Speaker TJ, Lara MF, González-González E, Flores MA, Contag CH, Kaspar RL.

Mol Imaging Biol. 2016 Feb;18(1):34-42. doi: 10.1007/s11307-015-0875-z.

PMID:
26169581
29.

Early Cancer Detection at the Epithelial Surface.

Rogalla S, Contag CH.

Cancer J. 2015 May-Jun;21(3):179-87. doi: 10.1097/PPO.0000000000000122. Review.

PMID:
26049697
30.

A real-time clinical endoscopic system for intraluminal, multiplexed imaging of surface-enhanced Raman scattering nanoparticles.

Garai E, Sensarn S, Zavaleta CL, Loewke NO, Rogalla S, Mandella MJ, Felt SA, Friedland S, Liu JT, Gambhir SS, Contag CH.

PLoS One. 2015 Apr 29;10(4):e0123185. doi: 10.1371/journal.pone.0123185. eCollection 2015.

31.

Methods for culturing human femur tissue explants to study breast cancer cell colonization of the metastatic niche.

Templeton ZS, Bachmann MH, Alluri RV, Maloney WJ, Contag CH, King BL.

J Vis Exp. 2015 Mar 15;(97). doi: 10.3791/52656.

32.

Detection of non-melanoma skin cancer by in vivo fluorescence imaging with fluorocoxib A.

Ra H, González-González E, Uddin MJ, King BL, Lee A, Ali-Khan I, Marnett LJ, Tang JY, Contag CH.

Neoplasia. 2015 Feb;17(2):201-7. doi: 10.1016/j.neo.2014.12.009.

33.

Differential fates of biomolecules delivered to target cells via extracellular vesicles.

Kanada M, Bachmann MH, Hardy JW, Frimannson DO, Bronsart L, Wang A, Sylvester MD, Schmidt TL, Kaspar RL, Butte MJ, Matin AC, Contag CH.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1433-42. doi: 10.1073/pnas.1418401112. Epub 2015 Feb 23.

34.

Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging.

Lobatto ME, Calcagno C, Millon A, Senders ML, Fay F, Robson PM, Ramachandran S, Binderup T, Paridaans MP, Sensarn S, Rogalla S, Gordon RE, Cardoso L, Storm G, Metselaar JM, Contag CH, Stroes ES, Fayad ZA, Mulder WJ.

ACS Nano. 2015 Feb 24;9(2):1837-47. doi: 10.1021/nn506750r. Epub 2015 Jan 28.

35.

[99mTc]Annexin V-128 SPECT Monitoring of Splenic and Disseminated Listeriosis in Mice: a Model of Imaging Sepsis.

Hardy JW, Levashova Z, Schmidt TL, Contag CH, Blankenberg FG.

Mol Imaging Biol. 2015 Jun;17(3):345-54. doi: 10.1007/s11307-014-0804-6.

PMID:
25416406
36.

A killer choice for cancer immunotherapy.

Schmidt TL, Negrin RS, Contag CH.

Immunol Res. 2014 May;58(2-3):300-6. doi: 10.1007/s12026-014-8507-2. Review.

PMID:
24791943
37.

Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein.

Chu J, Haynes RD, Corbel SY, Li P, González-González E, Burg JS, Ataie NJ, Lam AJ, Cranfill PJ, Baird MA, Davidson MW, Ng HL, Garcia KC, Contag CH, Shen K, Blau HM, Lin MZ.

Nat Methods. 2014 May;11(5):572-8. doi: 10.1038/nmeth.2888. Epub 2014 Mar 16.

38.

Reporter gene technologies for imaging cell fates in hematopoiesis.

Kusy S, Contag CH.

Methods Mol Biol. 2014;1109:1-22. doi: 10.1007/978-1-4614-9437-9_1.

PMID:
24473775
39.

Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device.

Hickerson RP, Wey WC, Rimm DL, Speaker T, Suh S, Flores MA, Gonzalez-Gonzalez E, Leake D, Contag CH, Kaspar RL.

Mol Ther Nucleic Acids. 2013 Oct 22;2:e129. doi: 10.1038/mtna.2013.56.

40.

High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device.

Garai E, Sensarn S, Zavaleta CL, Van de Sompel D, Loewke NO, Mandella MJ, Gambhir SS, Contag CH.

J Biomed Opt. 2013 Sep;18(9):096008. doi: 10.1117/1.JBO.18.9.096008.

41.

Monitoring dynamic interactions between breast cancer cells and human bone tissue in a co-culture model.

Contag CH, Lie WR, Bammer MC, Hardy JW, Schmidt TL, Maloney WJ, King BL.

Mol Imaging Biol. 2014 Apr;16(2):158-66. doi: 10.1007/s11307-013-0685-0.

42.

Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia.

Chen IY, Gheysens O, Li Z, Rasooly JA, Wang Q, Paulmurugan R, Rosenberg J, Rodriguez-Porcel M, Willmann JK, Wang DS, Contag CH, Robbins RC, Wu JC, Gambhir SS.

Hum Gene Ther Methods. 2013 Oct;24(5):279-88. doi: 10.1089/hgtb.2013.028.

43.

A Raman-based endoscopic strategy for multiplexed molecular imaging.

Zavaleta CL, Garai E, Liu JT, Sensarn S, Mandella MJ, Van de Sompel D, Friedland S, Van Dam J, Contag CH, Gambhir SS.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2288-97. doi: 10.1073/pnas.1211309110. Epub 2013 May 23.

44.

Visualizing cellular interactions with a generalized proximity reporter.

Sellmyer MA, Bronsart L, Imoto H, Contag CH, Wandless TJ, Prescher JA.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8567-72. doi: 10.1073/pnas.1218336110. Epub 2013 May 6.

45.

Real-time pathology through in vivo microscopy.

Liu JT, Loewke NO, Mandella MJ, Leigh SY, Levenson RM, Crawford JM, Contag CH.

Stud Health Technol Inform. 2013;185:235-64. Review.

PMID:
23542938
46.

Microscopic Delineation of Medulloblastoma Margins in a Transgenic Mouse Model Using a Topically Applied VEGFR-1 Probe.

Wang D, Chen Y, Leigh SY, Haeberle H, Contag CH, Liu JT.

Transl Oncol. 2012 Dec;5(6):408-14. Epub 2012 Dec 1.

47.

Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept.

Chong RH, Gonzalez-Gonzalez E, Lara MF, Speaker TJ, Contag CH, Kaspar RL, Coulman SA, Hargest R, Birchall JC.

J Control Release. 2013 Mar 28;166(3):211-9. doi: 10.1016/j.jconrel.2012.12.030. Epub 2013 Jan 8.

48.

Advancing the translation of optical imaging agents for clinical imaging.

Sevick-Muraca EM, Akers WJ, Joshi BP, Luker GD, Cutler CS, Marnett LJ, Contag CH, Wang TD, Azhdarinia A.

Biomed Opt Express. 2013 Jan 1;4(1):160-70. doi: 10.1364/BOE.4.000160. Epub 2012 Dec 18.

49.

Femtosecond plasma mediated laser ablation has advantages over mechanical osteotomy of cranial bone.

Lo DD, Mackanos MA, Chung MT, Hyun JS, Montoro DT, Grova M, Liu C, Wang J, Palanker D, Connolly AJ, Longaker MT, Contag CH, Wan DC.

Lasers Surg Med. 2012 Dec;44(10):805-14. doi: 10.1002/lsm.22098. Epub 2012 Nov 26.

PMID:
23184427
50.

Intravital fluorescence imaging of small interfering RNA-mediated gene repression in a dual reporter melanoma xenograft model.

Hickerson RP, Gonzalez-Gonzalez E, Vlassov AV, Li M, Lara MF, Contag CH, Kaspar RL.

Nucleic Acid Ther. 2012 Dec;22(6):438-43. doi: 10.1089/nat.2012.0364. Epub 2012 Oct 25.

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