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Items: 1 to 50 of 139


Resurrection of the ancestral RH5 invasion ligand provides a molecular explanation for the origin of P. falciparum malaria in humans.

Galaway F, Yu R, Constantinou A, Prugnolle F, Wright GJ.

PLoS Biol. 2019 Oct 15;17(10):e3000490. doi: 10.1371/journal.pbio.3000490. eCollection 2019 Oct.


d-a-Tocopheryl Polyethylene Glycol 1000 Succinate and a small-molecule Survivin suppressant synergistically induce apoptosis in SKBR3 breast cancer cells.

Neophytou CM, Mesaritis A, Gregoriou G, Constantinou AI.

Sci Rep. 2019 Oct 7;9(1):14375. doi: 10.1038/s41598-019-50884-9.


A review of the valorization and management of industrial spent catalyst waste in the context of sustainable practice: The case of the State of Kuwait in parallel to European industry.

Majed Al-Salem S, Constantinou A, Leeke GA, Hafeez S, Safdar T, Karam HJ, Al-Qassimi M, Al-Dhafeeri AT, Manos G, Arena U.

Waste Manag Res. 2019 Nov;37(11):1127-1141. doi: 10.1177/0734242X19876689. Epub 2019 Oct 1. Review.


Unravelling the potential of seaweeds from the Black Sea coast of Romania as bioactive compounds sources. Part I: Cystoseira barbata (Stackhouse) C. Agardh.

Trifan A, Vasincu A, Luca SV, Neophytou C, Wolfram E, Opitz SEW, Sava D, Bucur L, Cioroiu BI, Miron A, Aprotosoaie AC, Cioanca O, Hancianu M, Jitareanu A, Constantinou AI.

Food Chem Toxicol. 2019 Dec;134:110820. doi: 10.1016/j.fct.2019.110820. Epub 2019 Sep 17.


Plastic Solid Waste (PSW) in the Context of Life Cycle Assessment (LCA) and Sustainable Management.

Antelava A, Damilos S, Hafeez S, Manos G, Al-Salem SM, Sharma BK, Kohli K, Constantinou A.

Environ Manage. 2019 Aug;64(2):230-244. doi: 10.1007/s00267-019-01178-3. Epub 2019 Jun 22.


Frontal fibrosing alopecia: demographic and clinical characteristics of 490 cases.

Kanti V, Constantinou A, Reygagne P, Vogt A, Kottner J, Blume-Peytavi U.

J Eur Acad Dermatol Venereol. 2019 Oct;33(10):1976-1983. doi: 10.1111/jdv.15735. Epub 2019 Jul 1.


A tumor suppressive DNA translocase named FANCM.

Basbous J, Constantinou A.

Crit Rev Biochem Mol Biol. 2019 Feb;54(1):27-40. doi: 10.1080/10409238.2019.1568963. Epub 2019 Feb 4.


Evaluation of Epstein-Barr virus-specific antibodies in Cypriot multiple sclerosis patients.

Deeba E, Koptides D, Gaglia E, Constantinou A, Lambrianides A, Pantzaris M, Krashias G, Christodoulou C.

Mol Immunol. 2019 Jan;105:270-275. doi: 10.1016/j.molimm.2018.12.010. Epub 2018 Dec 15.


Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling.

Kumbhar R, Vidal-Eychenié S, Kontopoulos DG, Larroque M, Larroque C, Basbous J, Kossida S, Ribeyre C, Constantinou A.

Life Sci Alliance. 2018 Jun 21;1(3):e201800096. doi: 10.26508/lsa.201800096. eCollection 2018 Jun.


How tall buildings affect turbulent air flows and dispersion of pollution within a neighbourhood.

Aristodemou E, Boganegra LM, Mottet L, Pavlidis D, Constantinou A, Pain C, Robins A, ApSimon H.

Environ Pollut. 2018 Feb;233:782-796. doi: 10.1016/j.envpol.2017.10.041. Epub 2017 Nov 10.


Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors.

Moriel-Carretero M, Ovejero S, Gérus-Durand M, Vryzas D, Constantinou A.

J Cell Biol. 2017 Dec 4;216(12):4007-4026. doi: 10.1083/jcb.201702136. Epub 2017 Oct 13.


The future of the London Buy-To-Let property market: Simulation with temporal Bayesian Networks.

Constantinou AC, Fenton N.

PLoS One. 2017 Jun 27;12(6):e0179297. doi: 10.1371/journal.pone.0179297. eCollection 2017.


A review on thermal and catalytic pyrolysis of plastic solid waste (PSW).

Al-Salem SM, Antelava A, Constantinou A, Manos G, Dutta A.

J Environ Manage. 2017 Jul 15;197:177-198. doi: 10.1016/j.jenvman.2017.03.084. Epub 2017 Apr 4. Review.


RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma.

Viziteu E, Klein B, Basbous J, Lin YL, Hirtz C, Gourzones C, Tiers L, Bruyer A, Vincent L, Grandmougin C, Seckinger A, Goldschmidt H, Constantinou A, Pasero P, Hose D, Moreaux J.

Leukemia. 2017 Oct;31(10):2104-2113. doi: 10.1038/leu.2017.54. Epub 2017 Feb 10.


A Comprehensive Systematic Study on Thermoresponsive Gels: Beyond the Common Architectures of Linear Terpolymers.

Constantinou AP, Zhao H, McGilvery CM, Porter AE, Georgiou TK.

Polymers (Basel). 2017 Jan 20;9(1). pii: E31. doi: 10.3390/polym9010031.


Yeast GPCR signaling reflects the fraction of occupied receptors, not the number.

Bush A, Vasen G, Constantinou A, Dunayevich P, Patop IL, Blaustein M, Colman-Lerner A.

Mol Syst Biol. 2016 Dec 29;12(12):898. doi: 10.15252/msb.20166910.


Improving risk management for violence in mental health services: a multimethods approach.

Coid JW, Ullrich S, Kallis C, Freestone M, Gonzalez R, Bui L, Igoumenou A, Constantinou A, Fenton N, Marsh W, Yang M, DeStavola B, Hu J, Shaw J, Doyle M, Archer-Power L, Davoren M, Osumili B, McCrone P, Barrett K, Hindle D, Bebbington P.

Southampton (UK): NIHR Journals Library; 2016 Nov.


Intelligent Approach to Solvent Substitution: The Identification of a New Class of Levoglucosenone Derivatives.

Alves Costa Pacheco A, Sherwood J, Zhenova A, McElroy CR, Hunt AJ, Parker HL, Farmer TJ, Constantinou A, De Bruyn M, Whitwood AC, Raverty W, Clark JH.

ChemSusChem. 2016 Dec 20;9(24):3503-3512. doi: 10.1002/cssc.201600795. Epub 2016 Nov 17.


Selective activation of TNFR1 and NF-κB inhibition by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells.

Savva CG, Totokotsopoulos S, Nicolaou KC, Neophytou CM, Constantinou AI.

BMC Cancer. 2016 Apr 20;16:279. doi: 10.1186/s12885-016-2310-5.


Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks.

Ribeyre C, Zellweger R, Chauvin M, Bec N, Larroque C, Lopes M, Constantinou A.

Cell Rep. 2016 Apr 12;15(2):300-9. doi: 10.1016/j.celrep.2016.03.027. Epub 2016 Mar 31.


Greek cultural adaption and validation of the Kujala anterior knee pain scale in patients with patellofemoral pain syndrome.

Papadopoulos C, Constantinou A, Cheimonidou AZ, Stasinopoulos D.

Disabil Rehabil. 2017 Apr;39(7):704-708. doi: 10.3109/09638288.2016.1161834. Epub 2016 Apr 6.


Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage.

Alsafadi S, Houy A, Battistella A, Popova T, Wassef M, Henry E, Tirode F, Constantinou A, Piperno-Neumann S, Roman-Roman S, Dutertre M, Stern MH.

Nat Commun. 2016 Feb 4;7:10615. doi: 10.1038/ncomms10615.


From complex questionnaire and interviewing data to intelligent Bayesian network models for medical decision support.

Constantinou AC, Fenton N, Marsh W, Radlinski L.

Artif Intell Med. 2016 Feb;67:75-93. doi: 10.1016/j.artmed.2016.01.002. Epub 2016 Jan 16.


Value of information analysis for interventional and counterfactual Bayesian networks in forensic medical sciences.

Constantinou AC, Yet B, Fenton N, Neil M, Marsh W.

Artif Intell Med. 2016 Jan;66:41-52. doi: 10.1016/j.artmed.2015.09.002. Epub 2015 Sep 8.


Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis.

Papageorgis P, Ozturk S, Lambert AW, Neophytou CM, Tzatsos A, Wong CK, Thiagalingam S, Constantinou AI.

Breast Cancer Res. 2015 Jul 25;17:98. doi: 10.1186/s13058-015-0607-y.


Drug Delivery Innovations for Enhancing the Anticancer Potential of Vitamin E Isoforms and Their Derivatives.

Neophytou CM, Constantinou AI.

Biomed Res Int. 2015;2015:584862. doi: 10.1155/2015/584862. Epub 2015 Jun 7. Review.


LiSIs: An Online Scientific Workflow System for Virtual Screening.

Kannas CC, Kalvari I, Lambrinidis G, Neophytou CM, Savva CG, Kirmitzoglou I, Antoniou Z, Achilleos KG, Scherf D, Pitta CA, Nicolaou CA, Mikros E, Promponas VJ, Gerhauser C, Mehta RG, Constantinou AI, Pattichis CS.

Comb Chem High Throughput Screen. 2015;18(3):281-95.


Vernonia kotschyana roots: therapeutic potential via antioxidant activity.

Vasincu A, Paulsen BS, Diallo D, Vasincu I, Aprotosoaie AC, Bild V, Charalambous C, Constantinou AI, Miron A, Gavrilescu CM.

Molecules. 2014 Nov 19;19(11):19114-36. doi: 10.3390/molecules191119114.


DNA repair in diffuse large B-cell lymphoma: a molecular portrait.

Bret C, Klein B, Cartron G, Schved JF, Constantinou A, Pasero P, Moreaux J.

Br J Haematol. 2015 Apr;169(2):296-9. doi: 10.1111/bjh.13206. Epub 2014 Nov 5. No abstract available.


Dihydrolevoglucosenone (Cyrene) as a bio-based alternative for dipolar aprotic solvents.

Sherwood J, De bruyn M, Constantinou A, Moity L, McElroy CR, Farmer TJ, Duncan T, Raverty W, Hunt AJ, Clark JH.

Chem Commun (Camb). 2014 Sep 4;50(68):9650-2. doi: 10.1039/c4cc04133j.


In vitro antioxidant activity and phenolic content of Cedrus brevifolia bark.

Cretu E, Salminen JP, Karonen M, Miron A, Charalambous C, Constantinou AI, Aprotosoaie AC.

Nat Prod Commun. 2014 Apr;9(4):481-2.


A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy.

Kassambara A, Gourzones-Dmitriev C, Sahota S, Rème T, Moreaux J, Goldschmidt H, Constantinou A, Pasero P, Hose D, Klein B.

Oncotarget. 2014 May 15;5(9):2487-98.


Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation.

Jedrzejewski PM, del Val IJ, Constantinou A, Dell A, Haslam SM, Polizzi KM, Kontoravdi C.

Int J Mol Sci. 2014 Mar 14;15(3):4492-522. doi: 10.3390/ijms15034492.


D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells.

Neophytou CM, Constantinou C, Papageorgis P, Constantinou AI.

Biochem Pharmacol. 2014 May 1;89(1):31-42. doi: 10.1016/j.bcp.2014.02.003. Epub 2014 Feb 20.


FIBS-enabled noninvasive metabolic profiling.

Behjousiar A, Constantinou A, Polizzi KM, Kontoravdi C.

J Vis Exp. 2014 Feb 3;(84):e51200. doi: 10.3791/51200.


Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing.

Laguette N, Brégnard C, Hue P, Basbous J, Yatim A, Larroque M, Kirchhoff F, Constantinou A, Sobhian B, Benkirane M.

Cell. 2014 Jan 16;156(1-2):134-45. doi: 10.1016/j.cell.2013.12.011. Epub 2014 Jan 9.


Stripping of acetone from water with microfabricated and membrane gas-liquid contactors.

Constantinou A, Ghiotto F, Lam KF, Gavriilidis A.

Analyst. 2014 Jan 7;139(1):266-72. doi: 10.1039/c3an00963g.


In vitro study on the antioxidant activity of a polyphenol-rich extract from Pinus brutia bark and its fractions.

Cretu E, Karonen M, Salminen JP, Mircea C, Trifan A, Charalambous C, Constantinou AI, Miron A.

J Med Food. 2013 Nov;16(11):984-91. doi: 10.1089/jmf.2013.0050. Epub 2013 Nov 6.


Opportunities for bioprocess monitoring using FRET biosensors.

Constantinou A, Polizzi KM.

Biochem Soc Trans. 2013 Oct;41(5):1146-51. doi: 10.1042/BST20130103. Review.


FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.

Lossaint G, Larroque M, Ribeyre C, Bec N, Larroque C, Décaillet C, Gari K, Constantinou A.

Mol Cell. 2013 Sep 12;51(5):678-90. doi: 10.1016/j.molcel.2013.07.023. Epub 2013 Aug 29.


DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment.

Gourzones-Dmitriev C, Kassambara A, Sahota S, Rème T, Moreaux J, Bourquard P, Hose D, Pasero P, Constantinou A, Klein B.

Cell Cycle. 2013 Sep 1;12(17):2760-73. doi: 10.4161/cc.25951. Epub 2013 Aug 9. Review.


DNA structure-specific priming of ATR activation by DNA-PKcs.

Vidal-Eychenié S, Décaillet C, Basbous J, Constantinou A.

J Cell Biol. 2013 Aug 5;202(3):421-9. doi: 10.1083/jcb.201304139. Epub 2013 Jul 29.


Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance.

Pitta CA, Papageorgis P, Charalambous C, Constantinou AI.

Cancer Lett. 2013 Sep 1;337(2):167-76. doi: 10.1016/j.canlet.2013.05.031. Epub 2013 Jun 7.


Enhanced nitrogen removal in trickling filter plants.

Dai Y, Constantinou A, Griffiths P.

Water Sci Technol. 2013;67(10):2273-80. doi: 10.2166/wst.2013.119.


Equol enhances tamoxifen's anti-tumor activity by induction of caspase-mediated apoptosis in MCF-7 breast cancer cells.

Charalambous C, Pitta CA, Constantinou AI.

BMC Cancer. 2013 May 15;13:238. doi: 10.1186/1471-2407-13-238.


Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol.

Odiatou EM, Skaltsounis AL, Constantinou AI.

Cancer Lett. 2013 Mar 1;330(1):113-21. doi: 10.1016/j.canlet.2012.11.035. Epub 2012 Nov 29.


Induction of discrete apoptotic pathways by bromo-substituted indirubin derivatives in invasive breast cancer cells.

Nicolaou KA, Liapis V, Evdokiou A, Constantinou C, Magiatis P, Skaltsounis AL, Koumas L, Costeas PA, Constantinou AI.

Biochem Biophys Res Commun. 2012 Aug 17;425(1):76-82. doi: 10.1016/j.bbrc.2012.07.053. Epub 2012 Jul 20.


Glycoengineering approach to half-life extension of recombinant biotherapeutics.

Chen C, Constantinou A, Chester KA, Vyas B, Canis K, Haslam SM, Dell A, Epenetos AA, Deonarain MP.

Bioconjug Chem. 2012 Aug 15;23(8):1524-33. doi: 10.1021/bc200624a. Epub 2012 Jul 11.


Separation of acetylcholinesterase inhibitors using polymeric surfactants in polyelectrolyte multilayer coatings.

Constantinou AS, Nicolaou IN, Kapnissi-Christodoulou CP.

J Chromatogr Sci. 2012 Mar;50(3):228-36. doi: 10.1093/chromsci/bmr050.


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