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Items: 1 to 50 of 250

1.

Three-Year Follow-Up of Phase 1 and 2a rAAV.sFLT-1 Subretinal Gene Therapy Trials for Exudative Age-Related Macular Degeneration.

Rakoczy EP, Magno AL, Lai CM, Pierce CM, Degli-Esposti MA, Blumenkranz MS, Constable IJ.

Am J Ophthalmol. 2019 Aug;204:113-123. doi: 10.1016/j.ajo.2019.03.006. Epub 2019 Mar 13.

PMID:
30878487
2.

ACUTE RETINAL NECROSIS ASSOCIATED WITH HERPES ZOSTER VACCINATION.

Menghini M, Raja V, Raiter J, Balaratnasingam C, Constable IJ.

Retin Cases Brief Rep. 2018 Jul 25. doi: 10.1097/ICB.0000000000000761. [Epub ahead of print]

PMID:
30048403
3.

Surgical Removal of Internal Limiting Membrane and Layering of AAV Vector on the Retina Under Air Enhances Gene Transfection in a Nonhuman Primate.

Teo KYC, Lee SY, Barathi AV, Tun SBB, Tan L, Constable IJ.

Invest Ophthalmol Vis Sci. 2018 Jul 2;59(8):3574-3583. doi: 10.1167/iovs.18-24333.

4.

Intrasession Repeatability and Interocular Symmetry of Foveal Avascular Zone and Retinal Vessel Density in OCT Angiography.

Chen FK, Menghini M, Hansen A, Mackey DA, Constable IJ, Sampson DM.

Transl Vis Sci Technol. 2018 Jan 19;7(1):6. doi: 10.1167/tvst.7.1.6. eCollection 2018 Jan.

5.

Intersession Test-Retest Variability of Microperimetry in Type 2 Macular Telangiectasia.

Wong EN, De Soyza JDA, Mackey DA, Constable IJ, Chen FK.

Transl Vis Sci Technol. 2017 Dec 12;6(6):7. doi: 10.1167/tvst.6.6.7. eCollection 2017 Dec.

6.

Gene Therapy in Neovascular Age-related Macular Degeneration: Three-Year Follow-up of a Phase 1 Randomized Dose Escalation Trial.

Constable IJ, Lai CM, Magno AL, French MA, Barone SB, Schwartz SD, Blumenkranz MS, Degli-Esposti MA, Rakoczy EP.

Am J Ophthalmol. 2017 May;177:150-158. doi: 10.1016/j.ajo.2017.02.018. Epub 2017 Feb 27.

PMID:
28245970
7.

Phase 2a Randomized Clinical Trial: Safety and Post Hoc Analysis of Subretinal rAAV.sFLT-1 for Wet Age-related Macular Degeneration.

Constable IJ, Pierce CM, Lai CM, Magno AL, Degli-Esposti MA, French MA, McAllister IL, Butler S, Barone SB, Schwartz SD, Blumenkranz MS, Rakoczy EP.

EBioMedicine. 2016 Dec;14:168-175. doi: 10.1016/j.ebiom.2016.11.016. Epub 2016 Nov 10.

8.

Gene Therapy for Age-Related Macular Degeneration.

Constable IJ, Blumenkranz MS, Schwartz SD, Barone S, Lai CM, Rakoczy EP.

Asia Pac J Ophthalmol (Phila). 2016 Jul-Aug;5(4):300-3. doi: 10.1097/APO.0000000000000222.

PMID:
27488071
9.

Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration.

Cuellar-Partida G, Craig JE, Burdon KP, Wang JJ, Vote BJ, Souzeau E, McAllister IL, Isaacs T, Lake S, Mackey DA, Constable IJ, Mitchell P, Hewitt AW, MacGregor S.

Sci Rep. 2016 May 31;6:26885. doi: 10.1038/srep26885.

10.

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R, Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE, Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G, Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M, Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I, Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S, Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP Jr, Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B, Merriam JC, Smith RT, Khan JC, Shahid H, Moore AT, McGrath JA, Laux R, Brantley MA Jr, Agarwal A, Ersoy L, Caramoy A, Langmann T, Saksens NT, de Jong EK, Hoyng CB, Cain MS, Richardson AJ, Martin TM, Blangero J, Weeks DE, Dhillon B, van Duijn CM, Doheny KF, Romm J, Klaver CC, Hayward C, Gorin MB, Klein ML, Baird PN, den Hollander AI, Fauser S, Yates JR, Allikmets R, Wang JJ, Schaumberg DA, Klein BE, Hagstrom SA, Chowers I, Lotery AJ, Léveillard T, Zhang K, Brilliant MH, Hewitt AW, Swaroop A, Chew EY, Pericak-Vance MA, DeAngelis M, Stambolian D, Haines JL, Iyengar SK, Weber BH, Abecasis GR, Heid IM.

Nat Genet. 2016 Feb;48(2):134-43. doi: 10.1038/ng.3448. Epub 2015 Dec 21.

11.

Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial.

Rakoczy EP, Lai CM, Magno AL, Wikstrom ME, French MA, Pierce CM, Schwartz SD, Blumenkranz MS, Chalberg TW, Degli-Esposti MA, Constable IJ.

Lancet. 2015 Dec 12;386(10011):2395-403. doi: 10.1016/S0140-6736(15)00345-1. Epub 2015 Sep 30.

PMID:
26431823
12.

Factors promoting success and influencing complications in laser-induced central vein bypass.

McAllister IL, Gillies ME, Smithies LA, Rochtchina E, Harper CA, Daniell MD, Constable IJ, Mitchell P.

Ophthalmology. 2012 Dec;119(12):2579-86. doi: 10.1016/j.ophtha.2012.06.047. Epub 2012 Sep 5.

PMID:
22959103
13.

Preclinical safety evaluation of subretinal AAV2.sFlt-1 in non-human primates.

Lai CM, Estcourt MJ, Himbeck RP, Lee SY, Yew-San Yeo I, Luu C, Loh BK, Lee MW, Barathi A, Villano J, Ang CL, van der Most RG, Constable IJ, Dismuke D, Samulski RJ, Degli-Esposti MA, Rakoczy EP.

Gene Ther. 2012 Oct;19(10):999-1009. doi: 10.1038/gt.2011.169. Epub 2011 Nov 10.

PMID:
22071974
14.

Comparison of visual acuity outcomes between ranibizumab and bevacizumab treatment in neovascular age-related macular degeneration.

Feng XF, Constable IJ, McAllister IL, Isaacs T.

Int J Ophthalmol. 2011;4(1):85-8. doi: 10.3980/j.issn.2222-3959.2011.01.20. Epub 2011 Feb 18.

15.

Photodynamic Therapy with Verteporfin for Corneal Neovascularisation.

Hall RC, Barrett GD, Barry CJ, Constable IJ.

Ophthalmic Surg Lasers Imaging. 2010 Mar 9:1-3. doi: 10.3928/15428877-20100215-81. [Epub ahead of print]

PMID:
20337292
16.

The Central Retinal Vein Bypass Study: a trial of laser-induced chorioretinal venous anastomosis for central retinal vein occlusion.

McAllister IL, Gillies ME, Smithies LA, Rochtchina E, Harper CA, Daniell MD, Constable IJ, Mitchell P.

Ophthalmology. 2010 May;117(5):954-65. doi: 10.1016/j.ophtha.2009.10.026. Epub 2010 Feb 16.

PMID:
20163872
17.

Complement factor H Y402H and C-reactive protein polymorphism and photodynamic therapy response in age-related macular degeneration.

Feng X, Xiao J, Longville B, Tan AX, Wu XN, Cooper MN, McAllister IL, Isaacs T, Palmer LJ, Constable IJ.

Ophthalmology. 2009 Oct;116(10):1908-12.e1. doi: 10.1016/j.ophtha.2009.03.011. Epub 2009 Aug 18.

PMID:
19692124
18.

In vivo imaging of ocular MCMV infection.

Zinkernagel MS, Petitjean C, Fleming P, Chinnery HR, Constable IJ, McMenamin PG, Degli-Esposti MA.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):369-74. doi: 10.1167/iovs.09-4083. Epub 2009 Aug 13.

PMID:
19684003
19.

Telemedical diagnosis of anterior segment eye diseases: validation of digital slit-lamp still images.

Kumar S, Yogesan K, Constable IJ.

Eye (Lond). 2009 Mar;23(3):652-60. doi: 10.1038/eye.2008.11. Epub 2008 Feb 15.

PMID:
18274557
20.

Glaucoma screening: analysis of conventional and telemedicine-friendly devices.

Kumar S, Giubilato A, Morgan W, Jitskaia L, Barry C, Bulsara M, Constable IJ, Yogesan K.

Clin Exp Ophthalmol. 2007 Apr;35(3):237-43.

PMID:
17430510
21.

Orbital implants: potential new directions.

Hicks CR, Morrison D, Lou X, Crawford GJ, Gadjatsy A, Constable IJ.

Expert Rev Med Devices. 2006 Nov;3(6):805-15. Review.

PMID:
17280545
22.

Laser photocoagulation: ocular research and therapy in diabetic retinopathy.

Graham CE, Binz N, Shen WY, Constable IJ, Rakoczy EP.

Adv Exp Med Biol. 2006;572:195-200. Review. No abstract available.

PMID:
17249575
23.

Telemedicine-friendly, portable tonometers: an evaluation for intraocular pressure screening.

Kumar S, Middlemiss C, Bulsara M, Guibilato A, Morgan W, Tay-Kearney ML, Constable IJ, Yogesan K.

Clin Exp Ophthalmol. 2006 Sep-Oct;34(7):666-70.

PMID:
16970760
24.

Diabetic screening in Western Australia: a photographer's perspective.

Barry CJ, Constable IJ, McAllister IL, Kanagasingam Y.

J Vis Commun Med. 2006 Jun;29(2):66-75.

PMID:
16928589
25.

Remote ophthalmology services: cost comparison of telemedicine and alternative service delivery options.

Kumar S, Tay-Kearney ML, Chaves F, Constable IJ, Yogesan K.

J Telemed Telecare. 2006;12(1):19-22.

PMID:
16438774
26.

Sifting the available evidence on age-related macular degeneration.

Constable IJ.

Clin Exp Optom. 2005 Sep;88(5):267-8. No abstract available.

27.

Retinal microvascular patency in the diabetic rat.

Ben-nun J, Alder VA, Constable IJ.

Int Ophthalmol. 2004 Jul;25(4):187-92. Epub 2005 Sep 29.

PMID:
16200444
28.

Emergency eye care in rural Australia: role of internet.

Kumar S, Yogesan K, Hudson B, Tay-Kearney ML, Constable IJ.

Eye (Lond). 2006 Dec;20(12):1342-4. Epub 2005 Sep 23.

PMID:
16179932
29.

Internet based ophthalmology service: impact assessment.

Kumar S, Tay-Kearney ML, Constable IJ, Yogesan K.

Br J Ophthalmol. 2005 Oct;89(10):1382-3. No abstract available.

30.

Reimbursement for internet based eye care.

Kumar S, Constable IJ, Yogesan K.

Br J Ophthalmol. 2005 Oct;89(10):1234-5. Review. No abstract available.

31.

Retinal image analysis: concepts, applications and potential.

Patton N, Aslam TM, MacGillivray T, Deary IJ, Dhillon B, Eikelboom RH, Yogesan K, Constable IJ.

Prog Retin Eye Res. 2006 Jan;25(1):99-127. Epub 2005 Sep 9. Review.

PMID:
16154379
32.

Long-term evaluation of AAV-mediated sFlt-1 gene therapy for ocular neovascularization in mice and monkeys.

Lai CM, Shen WY, Brankov M, Lai YK, Barnett NL, Lee SY, Yeo IY, Mathur R, Ho JE, Pineda P, Barathi A, Ang CL, Constable IJ, Rakoczy EP.

Mol Ther. 2005 Oct;12(4):659-68.

33.

A risk score as part of an evidence-based approach to the selection of corneal replacement surgery.

Hicks CR, Macvie O, Crawford GJ, Constable IJ.

Cornea. 2005 Jul;24(5):523-30.

PMID:
15968155
34.

Generation of transgenic mice with mild and severe retinal neovascularisation.

Lai CM, Dunlop SA, May LA, Gorbatov M, Brankov M, Shen WY, Binz N, Lai YK, Graham CE, Barry CJ, Constable IJ, Beazley LD, Rakoczy EP.

Br J Ophthalmol. 2005 Jul;89(7):911-6.

35.

Management and outcomes of postoperative endophthalmitis since the endophthalmitis vitrectomy study: the Endophthalmitis Population Study of Western Australia (EPSWA)'s fifth report.

Ng JQ, Morlet N, Pearman JW, Constable IJ, McAllister IL, Kennedy CJ, Isaacs T, Semmens JB; Team EPSWA.

Ophthalmology. 2005 Jul;112(7):1199-206.

PMID:
15921759
36.

Should telemedicine in eye care be funded in Australia?

Kumar SK, Kanagasingam Y, Constable IJ.

Med J Aust. 2004 Nov 15;181(10):583. No abstract available.

PMID:
15540983
37.

Age-related macular degeneration and its possible prevention.

Constable IJ.

Med J Aust. 2004 Nov 1;181(9):471-2. Review.

PMID:
15516188
38.

Virus-mediated secretion gene therapy--a potential treatment for ocular neovascularization.

Lai YK, Sharma S, Lai CM, Brankov M, Constable IJ, Rakoczy PE.

Adv Exp Med Biol. 2003;533:447-53. No abstract available.

PMID:
15180297
39.

Assessment of rAAV-mediated gene therapy in the Rpe65-/- mouse.

Rakoczy PE, Lai CM, Yu MJ, Daniels DM, Brankov M, Rae BC, Stoddart CW, Barnett NL, Martin-Iverson MT, Redmond TM, Narfstrom K, Zhou X, Constable IJ.

Adv Exp Med Biol. 2003;533:431-8. No abstract available.

PMID:
15180295
40.

Deposits in artificial corneas: risk factors and prevention.

Hicks CR, Chirila TV, Werner L, Crawford GJ, Apple DJ, Constable IJ.

Clin Exp Ophthalmol. 2004 Apr;32(2):185-91.

PMID:
15068437
41.

Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey.

Shen WY, Lee SY, Yeo I, Lai CM, Mathur R, Tan D, Constable IJ, Rakoczy PE.

Arch Ophthalmol. 2004 Mar;122(3):353-60.

PMID:
15006849
42.

Tele-ophthalmology in India. Is it here to stay?

Kumar KR, Yogesan K, Constable IJ.

Indian J Ophthalmol. 2003 Dec;51(4):295-6. No abstract available.

43.

Thioridazine retinopathy.

Hadden PW, Tay-Kearney ML, Barry CJ, Constable IJ.

Clin Exp Ophthalmol. 2003 Dec;31(6):533-4. No abstract available.

PMID:
14641163
44.

Quantitative model demonstrating that recombinant adeno-associated virus and green fluorescent protein are non-toxic to the rat retina.

Daniels DM, Shen WY, Constable IJ, Rakoczy PE.

Clin Exp Ophthalmol. 2003 Oct;31(5):439-44.

PMID:
14516434
45.

AlphaCor cases: comparative outcomes.

Hicks CR, Crawford GJ, Tan DT, Snibson GR, Sutton GL, Downie N, Gondhowiardjo TD, Lam DS, Werner L, Apple D, Constable IJ.

Cornea. 2003 Oct;22(7):583-90. Review.

PMID:
14508253
46.

Differentiation of marrow stromal cells into photoreceptors in the rat eye.

Kicic A, Shen WY, Wilson AS, Constable IJ, Robertson T, Rakoczy PE.

J Neurosci. 2003 Aug 27;23(21):7742-9.

47.

Practical considerations of recombinant adeno-associated virus-mediated gene transfer for treatment of retinal degenerations.

Shen WY, Lai CM, Lai YK, Zhang D, Zaknich T, Sutanto EN, Constable IJ, Rakoczy PE.

J Gene Med. 2003 Jul;5(7):576-87.

PMID:
12825197
48.

Corneal replacement using a synthetic hydrogel cornea, AlphaCor: device, preliminary outcomes and complications.

Hicks CR, Crawford GJ, Lou X, Tan DT, Snibson GR, Sutton G, Downie N, Werner L, Chirila TV, Constable IJ.

Eye (Lond). 2003 Apr;17(3):385-92.

PMID:
12724702
49.

Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model.

Rakoczy PE, Zhang D, Robertson T, Barnett NL, Papadimitriou J, Constable IJ, Lai CM.

Am J Pathol. 2002 Oct;161(4):1515-24.

50.

Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy.

Lai YK, Shen WY, Brankov M, Lai CM, Constable IJ, Rakoczy PE.

Gene Ther. 2002 Jun;9(12):804-13.

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