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Items: 1 to 50 of 114

1.

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.

Pang SS, Bayly-Jones C, Radjainia M, Spicer BA, Law RHP, Hodel AW, Parsons ES, Ekkel SM, Conroy PJ, Ramm G, Venugopal H, Bird PI, Hoogenboom BW, Voskoboinik I, Gambin Y, Sierecki E, Dunstone MA, Whisstock JC.

Nat Commun. 2019 Sep 19;10(1):4288. doi: 10.1038/s41467-019-12279-2.

2.

Aphasia and stroke therapeutic alliance measure (A-STAM): Development and preliminary psychometric evaluation.

Lawton M, Conroy P, Sage K, Haddock G.

Int J Speech Lang Pathol. 2019 Oct;21(5):459-469. doi: 10.1080/17549507.2019.1648551. Epub 2019 Aug 15.

PMID:
31416382
3.

Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding.

Quek AJH, Mazzitelli BA, Wu G, Leung EWW, Caradoc-Davies TT, Lloyd GJ, Jeevarajah D, Conroy PJ, Sanderson-Smith M, Yuan Y, Ayinuola YA, Castellino FJ, Whisstock JC, Law RHP.

J Mol Biol. 2019 Sep 6;431(19):3804-3813. doi: 10.1016/j.jmb.2019.07.003. Epub 2019 Jul 8.

PMID:
31295457
4.

Enhancing Recovery After Kasai Portoenterostomy With Epidural Analgesia.

Phelps HM, Robinson JR, Chen H, Luckett TR, Conroy PC, Gillis LA, Hays SR, Lovvorn HN 3rd.

J Surg Res. 2019 Nov;243:354-362. doi: 10.1016/j.jss.2019.05.059. Epub 2019 Jul 2.

PMID:
31277012
5.

Development of a simulation-based sub-module in undergraduate medical education.

Morris MC, Conroy P.

Ir J Med Sci. 2019 Jun 26. doi: 10.1007/s11845-019-02050-3. [Epub ahead of print]

PMID:
31243695
6.

People with aphasia's perspectives of the therapeutic alliance during speech-language intervention: A Q methodological approach.

Lawton M, Haddock G, Conroy P, Serrant L, Sage K.

Int J Speech Lang Pathol. 2019 Apr 15:1-11. doi: 10.1080/17549507.2019.1585949. [Epub ahead of print]

PMID:
30987440
7.

Sensory optimisation of salt-reduced corned beef for different consumer segments.

Conroy PM, O'Sullivan MG, Hamill RM, Kerry JP.

Meat Sci. 2019 Aug;154:1-10. doi: 10.1016/j.meatsci.2019.03.015. Epub 2019 Mar 21.

PMID:
30954793
8.

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator.

Wu G, Mazzitelli BA, Quek AJ, Veldman MJ, Conroy PJ, Caradoc-Davies TT, Ooms LM, Tuck KL, Schoenecker JG, Whisstock JC, Law RHP.

Blood Adv. 2019 Mar 12;3(5):729-733. doi: 10.1182/bloodadvances.2018025429. No abstract available.

9.

Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3.

Traore DAK, Wisniewski JA, Flanigan SF, Conroy PJ, Panjikar S, Mok YF, Lao C, Griffin MDW, Adams V, Rood JI, Whisstock JC.

Nat Commun. 2018 Sep 13;9(1):3732. doi: 10.1038/s41467-018-06096-2.

10.

Demonstration of 40  GBaud intradyne transmission through worst-case atmospheric turbulence conditions for geostationary satellite uplink.

Conroy P, Surof J, Poliak J, Mata Calvo R.

Appl Opt. 2018 Jun 20;57(18):5095-5101. doi: 10.1364/AO.57.005095.

PMID:
30117971
11.

The first transmembrane region of complement component-9 acts as a brake on its self-assembly.

Spicer BA, Law RHP, Caradoc-Davies TT, Ekkel SM, Bayly-Jones C, Pang SS, Conroy PJ, Ramm G, Radjainia M, Venugopal H, Whisstock JC, Dunstone MA.

Nat Commun. 2018 Aug 15;9(1):3266. doi: 10.1038/s41467-018-05717-0.

12.

Noun and verb processing in aphasia: Behavioural profiles and neural correlates.

Alyahya RSW, Halai AD, Conroy P, Lambon Ralph MA.

Neuroimage Clin. 2018 Jan 31;18:215-230. doi: 10.1016/j.nicl.2018.01.023. eCollection 2018.

13.

Impact on the physical and sensory properties of salt-and fat-reduced traditional Irish breakfast sausages on various age cohorts acceptance.

Conroy PM, O'Sullivan MG, Hamill RM, Kerry JP.

Meat Sci. 2018 Sep;143:190-198. doi: 10.1016/j.meatsci.2018.04.037. Epub 2018 May 2.

PMID:
29778005
14.

Time for a quick word? The striking benefits of training speed and accuracy of word retrieval in post-stroke aphasia.

Conroy P, Sotiropoulou Drosopoulou C, Humphreys GF, Halai AD, Lambon Ralph MA.

Brain. 2018 Jun 1;141(6):1815-1827. doi: 10.1093/brain/awy087.

PMID:
29672757
15.

The behavioural patterns and neural correlates of concrete and abstract verb processing in aphasia: A novel verb semantic battery.

Alyahya RSW, Halai AD, Conroy P, Lambon Ralph MA.

Neuroimage Clin. 2017 Dec 6;17:811-825. doi: 10.1016/j.nicl.2017.12.009. eCollection 2018.

16.

Rapid resolution of hyperammonemia in neonates using extracorporeal membrane oxygenation as a platform to drive hemodialysis.

Robinson JR, Conroy PC, Hardison D, Hamid R, Grubb PH, Pietsch JB, Lovvorn HN 3rd.

J Perinatol. 2018 Jun;38(6):665-671. doi: 10.1038/s41372-018-0084-0. Epub 2018 Feb 21.

17.

Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.

Brennan AJ, Law RHP, Conroy PJ, Noori T, Lukoyanova N, Saibil H, Yagita H, Ciccone A, Verschoor S, Whisstock JC, Trapani JA, Voskoboinik I.

Cell Death Differ. 2018 Aug;25(8):1517-1529. doi: 10.1038/s41418-018-0057-z. Epub 2018 Feb 7.

18.

Speech and language therapists' perspectives of therapeutic alliance construction and maintenance in aphasia rehabilitation post-stroke.

Lawton M, Sage K, Haddock G, Conroy P, Serrant L.

Int J Lang Commun Disord. 2018 May;53(3):550-563. doi: 10.1111/1460-6984.12368. Epub 2018 Jan 18.

19.

X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors.

Law RHP, Wu G, Leung EWW, Hidaka K, Quek AJ, Caradoc-Davies TT, Jeevarajah D, Conroy PJ, Kirby NM, Norton RS, Tsuda Y, Whisstock JC.

Blood Adv. 2017 May 9;1(12):766-771. doi: 10.1182/bloodadvances.2016004150. eCollection 2017 May 9.

20.

A feasibility randomized controlled trial of ReaDySpeech for people with dysarthria after stroke.

Mitchell C, Bowen A, Tyson S, Conroy P.

Clin Rehabil. 2018 Aug;32(8):1037-1046. doi: 10.1177/0269215517748453. Epub 2017 Dec 26.

21.

Homodimerization attenuates the anti-inflammatory activity of interleukin-37.

Ellisdon AM, Nold-Petry CA, D'Andrea L, Cho SX, Lao JC, Rudloff I, Ngo D, Lo CY, Soares da Costa TP, Perugini MA, Conroy PJ, Whisstock JC, Nold MF.

Sci Immunol. 2017 Feb 10;2(8). pii: eaaj1548. doi: 10.1126/sciimmunol.aaj1548.

PMID:
28783685
22.

Perforin-A key (shaped) weapon in the immunological arsenal.

Spicer BA, Conroy PJ, Law RHP, Voskoboinik I, Whisstock JC.

Semin Cell Dev Biol. 2017 Dec;72:117-123. doi: 10.1016/j.semcdb.2017.07.033. Epub 2017 Jul 27. Review.

PMID:
28757431
23.

ReaDySpeech for people with dysarthria after stroke: protocol for a feasibility randomised controlled trial.

Mitchell C, Bowen A, Tyson S, Conroy P.

Pilot Feasibility Stud. 2017 Jul 20;4:25. doi: 10.1186/s40814-017-0169-0. eCollection 2018. Erratum in: Pilot Feasibility Stud. 2017 Oct 24;3:48.

24.

Sensory capability of young, middle-aged and elderly Irish assessors to identify beef steaks of varying texture.

Conroy PM, O' Sullivan MG, Hamill RM, Kerry JP.

Meat Sci. 2017 Oct;132:125-130. doi: 10.1016/j.meatsci.2017.05.020. Epub 2017 May 28.

PMID:
28629585
25.

Interventions for dysarthria due to stroke and other adult-acquired, non-progressive brain injury.

Mitchell C, Bowen A, Tyson S, Butterfint Z, Conroy P.

Cochrane Database Syst Rev. 2017 Jan 25;1:CD002088. doi: 10.1002/14651858.CD002088.pub3. Review.

26.

Antibodies: From novel repertoires to defining and refining the structure of biologically important targets.

Conroy PJ, Law RH, Caradoc-Davies TT, Whisstock JC.

Methods. 2017 Mar 1;116:12-22. doi: 10.1016/j.ymeth.2017.01.003. Epub 2017 Jan 11. Review.

PMID:
28088364
27.

Therapeutic Alliances in Stroke Rehabilitation: A Meta-Ethnography.

Lawton M, Haddock G, Conroy P, Sage K.

Arch Phys Med Rehabil. 2016 Nov;97(11):1979-1993. doi: 10.1016/j.apmr.2016.03.031. Epub 2016 Apr 30. Review.

PMID:
27137094
28.

Circumventing the stability-function trade-off in an engineered FN3 domain.

Porebski BT, Conroy PJ, Drinkwater N, Schofield P, Vazquez-Lombardi R, Hunter MR, Hoke DE, Christ D, McGowan S, Buckle AM.

Protein Eng Des Sel. 2016 Nov 1;29(11):541-550. doi: 10.1093/protein/gzw046.

29.

Eosinophil peroxidase activates cells by HER2 receptor engagement and β1-integrin clustering with downstream MAPK cell signaling.

Hennigan K, Conroy PJ, Walsh MT, Amin M, O'Kennedy R, Ramasamy P, Gleich GJ, Siddiqui Z, Glynn S, McCabe O, Mooney C, Harvey BJ, Costello RW, McBryan J.

Clin Immunol. 2016 Oct;171:1-11. doi: 10.1016/j.clim.2016.08.009. Epub 2016 Aug 9.

30.

Comprehensive N-Glycan Profiling of Avian Immunoglobulin Y.

Gilgunn S, Millán Martín S, Wormald MR, Zapatero-Rodríguez J, Conroy PJ, O'Kennedy RJ, Rudd PM, Saldova R.

PLoS One. 2016 Jul 26;11(7):e0159859. doi: 10.1371/journal.pone.0159859. eCollection 2016.

31.

Promoting linguistic complexity, greater message length and ease of engagement in email writing in people with aphasia: initial evidence from a study utilizing assistive writing software.

Thiel L, Sage K, Conroy P.

Int J Lang Commun Disord. 2017 Jan;52(1):106-124. doi: 10.1111/1460-6984.12261. Epub 2016 Jun 14.

PMID:
27297074
32.

Accessing rehabilitation after stroke - a guessing game?

Enderby P, Pandyan A, Bowen A, Hearnden D, Ashburn A, Conroy P, Logan P, Thompson C, Winter J.

Disabil Rehabil. 2017 Apr;39(7):709-713. doi: 10.3109/09638288.2016.1160448. Epub 2016 Apr 30.

33.

Corrigendum: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin.

Smith AI, Rajapakse NW, Kleifeld O, Lomonte B, Sikanyika NL, Spicer AJ, Hodgson WC, Conroy PJ, Small DH, Kaye DM, Parkington HC, Whisstock JC, Kuruppu S.

Sci Rep. 2016 Apr 22;6:24333. doi: 10.1038/srep24333. No abstract available.

34.

N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin.

Smith AI, Rajapakse NW, Kleifeld O, Lomonte B, Sikanyika NL, Spicer AJ, Hodgson WC, Conroy PJ, Small DH, Kaye DM, Parkington HC, Whisstock JC, Kuruppu S.

Sci Rep. 2016 Mar 2;6:22413. doi: 10.1038/srep22413. Erratum in: Sci Rep. 2016 Apr 22;6:24333.

35.

Structure of the poly-C9 component of the complement membrane attack complex.

Dudkina NV, Spicer BA, Reboul CF, Conroy PJ, Lukoyanova N, Elmlund H, Law RH, Ekkel SM, Kondos SC, Goode RJ, Ramm G, Whisstock JC, Saibil HR, Dunstone MA.

Nat Commun. 2016 Feb 4;7:10588. doi: 10.1038/ncomms10588.

36.

The role of learning in improving functional writing in stroke aphasia.

Thiel L, Sage K, Conroy P.

Disabil Rehabil. 2016 Oct;38(21):2122-34. doi: 10.3109/09638288.2015.1114038. Epub 2016 Jan 5.

PMID:
26727994
37.

Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.

Yagi H, Conroy PJ, Leung EW, Law RH, Trapani JA, Voskoboinik I, Whisstock JC, Norton RS.

J Biol Chem. 2015 Oct 16;290(42):25213-26. doi: 10.1074/jbc.M115.668384. Epub 2015 Aug 25.

38.

Investigation of the mechanism of interaction between Mannose-binding lectin-associated serine protease-2 and complement C4.

Drentin N, Conroy P, Gunzburg MJ, Pike RN, Wijeyewickrema LC.

Mol Immunol. 2015 Oct;67(2 Pt B):287-93. doi: 10.1016/j.molimm.2015.06.011. Epub 2015 Jun 27.

PMID:
26130224
39.

Comparing uni-modal and multi-modal therapies for improving writing in acquired dysgraphia after stroke.

Thiel L, Sage K, Conroy P.

Neuropsychol Rehabil. 2016;26(3):345-73. doi: 10.1080/09602011.2015.1026357. Epub 2015 Apr 9.

PMID:
25854414
40.

Outcomes of treatment targeting syntax production in people with Broca's-type aphasia: evidence from psycholinguistic assessment tasks and everyday conversation.

Carragher M, Sage K, Conroy P.

Int J Lang Commun Disord. 2015 May-Jun;50(3):322-36. doi: 10.1111/1460-6984.12135. Epub 2015 Feb 27.

PMID:
25727236
41.

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.

Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, Méndez J, Morrison CG, Passegué E.

Nature. 2014 Aug 14;512(7513):198-202. doi: 10.1038/nature13619. Epub 2014 Jul 30.

42.

Reconciling the structural attributes of avian antibodies.

Conroy PJ, Law RH, Gilgunn S, Hearty S, Caradoc-Davies TT, Lloyd G, O'Kennedy RJ, Whisstock JC.

J Biol Chem. 2014 May 30;289(22):15384-92. doi: 10.1074/jbc.M114.562470. Epub 2014 Apr 15.

43.

A comparison of errorless and errorful therapies for dysgraphia after stroke.

Thiel L, Conroy P.

Neuropsychol Rehabil. 2014;24(2):172-201. doi: 10.1080/09602011.2013.875925. Epub 2014 Feb 12.

PMID:
24517315
44.

A randomised prospective trial of intra-operative oesophageal Doppler-guided fluid administration in major gynaecological surgery.

McKenny M, Conroy P, Wong A, Farren M, Gleeson N, Walsh C, O'Malley C, Dowd N.

Anaesthesia. 2013 Dec;68(12):1224-31. doi: 10.1111/anae.12355. Epub 2013 Sep 30.

45.

A tale of two specificities: bispecific antibodies for therapeutic and diagnostic applications.

Byrne H, Conroy PJ, Whisstock JC, O'Kennedy RJ.

Trends Biotechnol. 2013 Nov;31(11):621-32. doi: 10.1016/j.tibtech.2013.08.007. Epub 2013 Oct 2. Review.

PMID:
24094861
46.

The effects of verb retrieval therapy for people with non-fluent aphasia: evidence from assessment tasks and conversation.

Carragher M, Sage K, Conroy P.

Neuropsychol Rehabil. 2013;23(6):846-87. doi: 10.1080/09602011.2013.832335. Epub 2013 Sep 13.

PMID:
24028211
47.

Calcium-binding capacity of centrin2 is required for linear POC5 assembly but not for nucleotide excision repair.

Dantas TJ, Daly OM, Conroy PC, Tomas M, Wang Y, Lalor P, Dockery P, Ferrando-May E, Morrison CG.

PLoS One. 2013 Jul 2;8(7):e68487. doi: 10.1371/journal.pone.0068487. Print 2013.

48.

Tumescent anaesthesia.

Conroy PH, O'Rourke J.

Surgeon. 2013 Aug;11(4):210-21. doi: 10.1016/j.surge.2012.12.009. Epub 2013 Feb 1. Review.

PMID:
23375489
49.

Real-time ultrasound-guided spinal anaesthesia: a prospective observational study of a new approach.

Conroy PH, Luyet C, McCartney CJ, McHardy PG.

Anesthesiol Res Pract. 2013;2013:525818. doi: 10.1155/2013/525818. Epub 2013 Jan 10.

50.

Aberrant PSA glycosylation--a sweet predictor of prostate cancer.

Gilgunn S, Conroy PJ, Saldova R, Rudd PM, O'Kennedy RJ.

Nat Rev Urol. 2013 Feb;10(2):99-107. doi: 10.1038/nrurol.2012.258. Epub 2013 Jan 15. Review.

PMID:
23318363

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