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Items: 28


Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites.

Luderman KD, Conroy JL, Free RB, Southall N, Ferrer M, Sanchez-Soto M, Moritz AE, Willette BKA, Fyfe TJ, Jain P, Titus S, Hazelwood LA, Aubé J, Lane JR, Frankowski KJ, Sibley DR.

Mol Pharmacol. 2018 Oct;94(4):1197-1209. doi: 10.1124/mol.118.113175. Epub 2018 Aug 1.


PNA-Based Multivalent Scaffolds Activate the Dopamine D2 Receptor.

Dix AV, Conroy JL, George Rosenker KM, Sibley DR, Appella DH.

ACS Med Chem Lett. 2015 Mar 13;6(4):425-9. doi: 10.1021/ml500478m. eCollection 2015 Apr 9.


Identification of G protein-biased agonists that fail to recruit β-arrestin or promote internalization of the D1 dopamine receptor.

Conroy JL, Free RB, Sibley DR.

ACS Chem Neurosci. 2015 Apr 15;6(4):681-92. doi: 10.1021/acschemneuro.5b00020. Epub 2015 Feb 20.


(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling.

Meade JA, Free RB, Miller NR, Chun LS, Doyle TB, Moritz AE, Conroy JL, Watts VJ, Sibley DR.

Psychopharmacology (Berl). 2015 Mar;232(5):917-30. doi: 10.1007/s00213-014-3726-8. Epub 2014 Sep 18.


Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.

Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer M, Javitch JA, Beuming T, Shi L, Southall NT, Marugan JJ, Sibley DR.

Mol Pharmacol. 2014 Jul;86(1):96-105. doi: 10.1124/mol.113.090563. Epub 2014 Apr 22.


Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.

Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer M, Titus S, Zheng W, Sibley DR, Marugan JJ.

J Med Chem. 2014 Apr 24;57(8):3450-63. doi: 10.1021/jm500126s. Epub 2014 Apr 10.


Varied response of western Pacific hydrology to climate forcings over the last glacial period.

Carolin SA, Cobb KM, Adkins JF, Clark B, Conroy JL, Lejau S, Malang J, Tuen AA.

Science. 2013 Jun 28;340(6140):1564-6. doi: 10.1126/science.1233797. Epub 2013 Jun 6.


CC12, a P450/epoxygenase inhibitor, acts in the rat rostral, ventromedial medulla to attenuate morphine antinociception.

Conroy JL, Nalwalk JW, Phillips JG, Hough LB.

Brain Res. 2013 Mar 7;1499:1-11. doi: 10.1016/j.brainres.2012.12.030. Epub 2013 Jan 5.


Modification of cocaine self-administration by buspirone (buspar®): potential involvement of D3 and D4 dopamine receptors.

Bergman J, Roof RA, Furman CA, Conroy JL, Mello NK, Sibley DR, Skolnick P.

Int J Neuropsychopharmacol. 2013 Mar;16(2):445-58. doi: 10.1017/S1461145712000661. Epub 2012 Jul 25.


A prospective randomised study of minimally invasive midvastus total knee arthroplasty compared with standard total knee arthroplasty.

Guy SP, Farndon MA, Conroy JL, Bennett C, Grainger AJ, London NJ.

Knee. 2012 Dec;19(6):866-71. doi: 10.1016/j.knee.2012.04.009. Epub 2012 May 18.


Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic.

Hough LB, Nalwalk JW, Yang J, Conroy JL, VanAlstine MA, Yang W, Gargano J, Shan Z, Zhang SZ, Wentland MP, Phillips JG, Knapp BI, Bidlack JM, Zuiderveld OP, Leurs R, Ding X.

Pain. 2011 Apr;152(4):878-87. doi: 10.1016/j.pain.2011.01.001.


Project ASPIRE: an Interactive, Multimedia Smoking Prevention and Cessation curriculum for culturally diverse high school students.

Prokhorov AV, Kelder SH, Shegog R, Conroy JL, Murray N, Peters R, Cinciripini PM, De Moor C, Hudmon KS, Ford KH.

Subst Use Misuse. 2010 May;45(6):983-1006. doi: 10.3109/10826080903038050.


Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling.

Conroy JL, Fang C, Gu J, Zeitlin SO, Yang W, Yang J, VanAlstine MA, Nalwalk JW, Albrecht PJ, Mazurkiewicz JE, Snyder-Keller A, Shan Z, Zhang SZ, Wentland MP, Behr M, Knapp BI, Bidlack JM, Zuiderveld OP, Leurs R, Ding X, Hough LB.

Nat Neurosci. 2010 Mar;13(3):284-6. doi: 10.1038/nn.2497. Epub 2010 Feb 7.


Case report: Rhodococcus erythropolis osteomyelitis in the toe.

Roy M, Sidhom S, Kerr KG, Conroy JL.

Clin Orthop Relat Res. 2009 Nov;467(11):3029-31. doi: 10.1007/s11999-009-0901-z. Epub 2009 May 21.


Impact of A Smoking Prevention Interactive Experience (ASPIRE), an interactive, multimedia smoking prevention and cessation curriculum for culturally diverse high-school students.

Prokhorov AV, Kelder SH, Shegog R, Murray N, Peters R Jr, Agurcia-Parker C, Cinciripini PM, de Moor C, Conroy JL, Hudmon KS, Ford KH, Marani S.

Nicotine Tob Res. 2008 Sep;10(9):1477-85. doi: 10.1080/14622200802323183.


Risk factors for revision for early dislocation in total hip arthroplasty.

Conroy JL, Whitehouse SL, Graves SE, Pratt NL, Ryan P, Crawford RW.

J Arthroplasty. 2008 Sep;23(6):867-72. doi: 10.1016/j.arth.2007.07.009. Epub 2008 Mar 7.


Does use of a "rim cutter" improve quality of cementation of the acetabular component of cemented exeter total hip arthroplasty?

Conroy JL, Chawda M, Kaushal R, Whitehouse SL, Crawford RW, English H.

J Arthroplasty. 2009 Jan;24(1):71-6. doi: 10.1016/j.arth.2008.01.130. Epub 2008 Apr 10.


School absence in children with fractures: is it unnecessary school regulations that keep children away from school?

Conroy JL, Conroy PM, Newman RJ.

Injury. 2006 May;37(5):398-401. Epub 2006 Feb 28.


The T4 syndrome.

Conroy JL, Schneiders AG.

Man Ther. 2005 Nov;10(4):292-6. No abstract available.


Molecular and functional analysis of glutamine uptake in human hepatoma and liver-derived cells.

Bode BP, Fuchs BC, Hurley BP, Conroy JL, Suetterlin JE, Tanabe KK, Rhoads DB, Abcouwer SF, Souba WW.

Am J Physiol Gastrointest Liver Physiol. 2002 Nov;283(5):G1062-73.


Effect of radial artery harvesting on tissue perfusion and function of the hand.

Rafael Sadaba J, Conroy JL, Burniston M, Maughan J, Munsch C.

Cardiovasc Surg. 2001 Aug;9(4):378-82.


Nicotine dependence, withdrawal symptoms, and adolescents' readiness to quit smoking.

Prokhorov AV, Hudmon KS, de Moor CA, Kelder SH, Conroy JL, Ordway N.

Nicotine Tob Res. 2001 May;3(2):151-5.


Impingement fracture of the posteromedial process of the talus--a case report.

Cohen AP, Conroy JL, Giannoudis PV, Matthews SJ, Smith M.

Acta Orthop Scand. 2000 Dec;71(6):642-4. No abstract available.


Tumor-influenced amino acid transport activities in zonal-enriched hepatocyte populations.

Easson AM, Pawlik TM, Fischer CP, Conroy JL, Sgroi D, Souba WW, Bode BP.

Am J Physiol Gastrointest Liver Physiol. 2000 Dec;279(6):G1209-18.


Hydrolysis of Amides Catalyzed by 4-Heterocyclohexanones: Small Molecule Mimics of Serine Proteases.

Ghosh M, Conroy JL, Seto CT.

Angew Chem Int Ed Engl. 1999 Feb 15;38(4):514-516. doi: 10.1002/(SICI)1521-3773(19990215)38:4<514::AID-ANIE514>3.0.CO;2-J.


Protein kinase C regulates nutrient uptake and growth in hepatoma cells.

Bode BP, Reuter N, Conroy JL, Souba WW.

Surgery. 1998 Aug;124(2):260-7; discussion 267-8.


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