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Items: 1 to 50 of 59

1.

Mitochondrial Alkbh1 localizes to mtRNA granules and its knockdown induces the mitochondrial UPR in humans and C. elegans.

Wagner A, Hofmeister O, Rolland SG, Maiser A, Aasumets K, Schmitt S, Schorpp K, Feuchtinger A, Hadian K, Schneider S, Zischka H, Leonhardt H, Conradt B, Gerhold JM, Wolf A.

J Cell Sci. 2019 Oct 1;132(19). pii: jcs223891. doi: 10.1242/jcs.223891.

PMID:
31434717
2.

Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt.

Rolland SG, Schneid S, Schwarz M, Rackles E, Fischer C, Haeussler S, Regmi SG, Yeroslaviz A, Habermann B, Mokranjac D, Lambie E, Conradt B.

Cell Rep. 2019 Aug 13;28(7):1659-1669.e5. doi: 10.1016/j.celrep.2019.07.049.

3.

PCMD-1 Organizes Centrosome Matrix Assembly in C. elegans.

Erpf AC, Stenzel L, Memar N, Antoniolli M, Osepashvili M, Schnabel R, Conradt B, Mikeladze-Dvali T.

Curr Biol. 2019 Apr 22;29(8):1324-1336.e6. doi: 10.1016/j.cub.2019.03.029. Epub 2019 Apr 11.

PMID:
30982652
4.

Twenty million years of evolution: The embryogenesis of four Caenorhabditis species are indistinguishable despite extensive genome divergence.

Memar N, Schiemann S, Hennig C, Findeis D, Conradt B, Schnabel R.

Dev Biol. 2019 Mar 15;447(2):182-199. doi: 10.1016/j.ydbio.2018.12.022. Epub 2018 Dec 25.

5.

Caenorhabditis elegans ced-3 Caspase Is Required for Asymmetric Divisions That Generate Cells Programmed To Die.

Mishra N, Wei H, Conradt B.

Genetics. 2018 Nov;210(3):983-998. doi: 10.1534/genetics.118.301500. Epub 2018 Sep 7.

6.

Overlapping expression patterns and functions of three paralogous P5B ATPases in Caenorhabditis elegans.

Zielich J, Tzima E, Schröder EA, Jemel F, Conradt B, Lambie EJ.

PLoS One. 2018 Mar 16;13(3):e0194451. doi: 10.1371/journal.pone.0194451. eCollection 2018.

7.

Caenorhabditis elegans CES-1 Snail Represses pig-1 MELK Expression To Control Asymmetric Cell Division.

Wei H, Yan B, Gagneur J, Conradt B.

Genetics. 2017 Aug;206(4):2069-2084. doi: 10.1534/genetics.117.202754. Epub 2017 Jun 26. Erratum in: Genetics. 2019 Feb;211(2):787.

8.

Partners in Crime.

Conradt B.

Dev Cell. 2017 Jun 19;41(6):573-574. doi: 10.1016/j.devcel.2017.06.002. Review.

9.

miRNAs cooperate in apoptosis regulation during C. elegans development.

Sherrard R, Luehr S, Holzkamp H, McJunkin K, Memar N, Conradt B.

Genes Dev. 2017 Jan 15;31(2):209-222. doi: 10.1101/gad.288555.116. Epub 2017 Feb 6.

10.

Programmed Cell Death During Caenorhabditis elegans Development.

Conradt B, Wu YC, Xue D.

Genetics. 2016 Aug;203(4):1533-62. doi: 10.1534/genetics.115.186247.

11.

Deadly dowry: how engulfment pathways promote cell killing.

Lambie EJ, Conradt B.

Cell Death Differ. 2016 Apr;23(4):553-4. doi: 10.1038/cdd.2015.170. Epub 2016 Feb 12. Review. No abstract available.

12.

Engulfment pathways promote programmed cell death by enhancing the unequal segregation of apoptotic potential.

Chakraborty S, Lambie EJ, Bindu S, Mikeladze-Dvali T, Conradt B.

Nat Commun. 2015 Dec 10;6:10126. doi: 10.1038/ncomms10126.

13.

The loss of LRPPRC function induces the mitochondrial unfolded protein response.

Köhler F, Müller-Rischart AK, Conradt B, Rolland SG.

Aging (Albany NY). 2015 Sep;7(9):701-17.

14.

Differential regulation of germline apoptosis in response to meiotic checkpoint activation.

Ye AL, Ragle JM, Conradt B, Bhalla N.

Genetics. 2014 Nov;198(3):995-1000. doi: 10.1534/genetics.114.170241. Epub 2014 Sep 11.

15.

Age-dependent changes in mitochondrial morphology and volume are not predictors of lifespan.

Regmi SG, Rolland SG, Conradt B.

Aging (Albany NY). 2014 Feb;6(2):118-30.

16.

A complex regulatory network coordinating cell cycles during C. elegans development is revealed by a genome-wide RNAi screen.

Roy SH, Tobin DV, Memar N, Beltz E, Holmen J, Clayton JE, Chiu DJ, Young LD, Green TH, Lubin I, Liu Y, Conradt B, Saito RM.

G3 (Bethesda). 2014 Feb 28;4(5):795-804. doi: 10.1534/g3.114.010546.

17.

Coordination of cell proliferation and cell fate determination by CES-1 snail.

Yan B, Memar N, Gallinger J, Conradt B.

PLoS Genet. 2013 Oct;9(10):e1003884. doi: 10.1371/journal.pgen.1003884. Epub 2013 Oct 31.

18.

CATP-6, a C. elegans ortholog of ATP13A2 PARK9, positively regulates GEM-1, an SLC16A transporter.

Lambie EJ, Tieu PJ, Lebedeva N, Church DL, Conradt B.

PLoS One. 2013 Oct 9;8(10):e77202. doi: 10.1371/journal.pone.0077202. eCollection 2013.

19.

A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis.

Zanin E, Desai A, Poser I, Toyoda Y, Andree C, Moebius C, Bickle M, Conradt B, Piekny A, Oegema K.

Dev Cell. 2013 Sep 16;26(5):496-510. doi: 10.1016/j.devcel.2013.08.005. Epub 2013 Sep 5.

20.

Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion.

Rolland SG, Motori E, Memar N, Hench J, Frank S, Winklhofer KF, Conradt B.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E2967-76. doi: 10.1073/pnas.1303872110. Epub 2013 Jul 22.

21.

Phagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans.

Shen Q, He B, Lu N, Conradt B, Grant BD, Zhou Z.

Development. 2013 Aug;140(15):3230-43. doi: 10.1242/dev.093732.

22.

Recombinant expression, biophysical characterization, and cardiolipin-induced changes of two Caenorhabditis elegans cytochrome c proteins.

Vincelli AJ, Pottinger DS, Zhong F, Hanske J, Rolland SG, Conradt B, Pletneva EV.

Biochemistry. 2013 Jan 29;52(4):653-66. doi: 10.1021/bi3014938. Epub 2013 Jan 16.

23.

A molecular switch that governs mitochondrial fusion and fission mediated by the BCL2-like protein CED-9 of Caenorhabditis elegans.

Lu Y, Rolland SG, Conradt B.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):E813-22. doi: 10.1073/pnas.1103218108. Epub 2011 Sep 23.

24.

Mitochondrial involvement in cell death of non-mammalian eukaryotes.

Abdelwahid E, Rolland S, Teng X, Conradt B, Hardwick JM, White K.

Biochim Biophys Acta. 2011 Apr;1813(4):597-607. doi: 10.1016/j.bbamcr.2010.10.008. Epub 2010 Oct 13. Review.

25.

New role of the BCL2 family of proteins in the regulation of mitochondrial dynamics.

Rolland SG, Conradt B.

Curr Opin Cell Biol. 2010 Dec;22(6):852-8. doi: 10.1016/j.ceb.2010.07.014. Epub 2010 Aug 20. Review.

26.

Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons.

Nehme R, Grote P, Tomasi T, Löser S, Holzkamp H, Schnabel R, Conradt B.

Cell Death Differ. 2010 Aug;17(8):1266-76. doi: 10.1038/cdd.2010.3. Epub 2010 Feb 12.

27.

Genetic control of programmed cell death during animal development.

Conradt B.

Annu Rev Genet. 2009;43:493-523. doi: 10.1146/annurev.genet.42.110807.091533. Review.

28.

The BCL-2-like protein CED-9 of C. elegans promotes FZO-1/Mfn1,2- and EAT-3/Opa1-dependent mitochondrial fusion.

Rolland SG, Lu Y, David CN, Conradt B.

J Cell Biol. 2009 Aug 24;186(4):525-40. doi: 10.1083/jcb.200905070.

29.

egl-1: a key activator of apoptotic cell death in C. elegans.

Nehme R, Conradt B.

Oncogene. 2008 Dec;27 Suppl 1:S30-40. doi: 10.1038/onc.2009.41. Review.

PMID:
19641505
30.

The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors.

Reece-Hoyes JS, Deplancke B, Barrasa MI, Hatzold J, Smit RB, Arda HE, Pope PA, Gaudet J, Conradt B, Walhout AJ.

Nucleic Acids Res. 2009 Jun;37(11):3689-98. doi: 10.1093/nar/gkp232. Epub 2009 Apr 16.

31.

Gem-1 encodes an SLC16 monocarboxylate transporter-related protein that functions in parallel to the gon-2 TRPM channel during gonad development in Caenorhabditis elegans.

Kemp BJ, Church DL, Hatzold J, Conradt B, Lambie EJ.

Genetics. 2009 Feb;181(2):581-91. doi: 10.1534/genetics.108.094870. Epub 2008 Dec 15.

32.

The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans.

Ow MC, Martinez NJ, Olsen PH, Silverman HS, Barrasa MI, Conradt B, Walhout AJ, Ambros V.

Genes Dev. 2008 Sep 15;22(18):2520-34. doi: 10.1101/gad.1678808.

33.

HLH-3 is a C. elegans Achaete/Scute protein required for differentiation of the hermaphrodite-specific motor neurons.

Doonan R, Hatzold J, Raut S, Conradt B, Alfonso A.

Mech Dev. 2008 Sep-Oct;125(9-10):883-93. doi: 10.1016/j.mod.2008.06.002. Epub 2008 Jun 11.

34.

Caenorhabditis elegans num-1 negatively regulates endocytic recycling.

Nilsson L, Conradt B, Ruaud AF, Chen CC, Hatzold J, Bessereau JL, Grant BD, Tuck S.

Genetics. 2008 May;179(1):375-87. doi: 10.1534/genetics.108.087247.

35.

Control of apoptosis by asymmetric cell division.

Hatzold J, Conradt B.

PLoS Biol. 2008 Apr 8;6(4):e84. doi: 10.1371/journal.pbio.0060084.

36.

Programmed cell death.

Conradt B, Xue D.

WormBook. 2005 Oct 6:1-13. Review.

37.

C. elegans orthologs of components of the RB tumor suppressor complex have distinct pro-apoptotic functions.

Schertel C, Conradt B.

Development. 2007 Oct;134(20):3691-701. Epub 2007 Sep 19.

38.

Cell biology: mitochondria shape up.

Conradt B.

Nature. 2006 Oct 12;443(7112):646-7. No abstract available.

PMID:
17035992
40.
41.

The role of mitochondria in apoptosis induction in Caenorhabditis elegans: more than just innocent bystanders?

Rolland S, Conradt B.

Cell Death Differ. 2006 Aug;13(8):1281-6. Epub 2006 May 26. No abstract available.

42.

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans.

Jagasia R, Grote P, Westermann B, Conradt B.

Nature. 2005 Feb 17;433(7027):754-60.

43.

C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.

Schumacher B, Schertel C, Wittenburg N, Tuck S, Mitani S, Gartner A, Conradt B, Shaham S.

Cell Death Differ. 2005 Feb;12(2):153-61. Erratum in: Cell Death Differ. 2005 May;12(5):532.

44.

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans.

Hoeppner DJ, Spector MS, Ratliff TM, Kinchen JM, Granat S, Lin SC, Bhusri SS, Conradt B, Herman MA, Hengartner MO.

Dev Biol. 2004 Oct 1;274(1):125-38.

45.

The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome.

Jäger S, Schwartz HT, Horvitz HR, Conradt B.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12549-54. Epub 2004 Aug 11.

47.

With a little help from your friends: cells don't die alone.

Conradt B.

Nat Cell Biol. 2002 Jun;4(6):E139-43. Review.

PMID:
12042826
48.

Cell engulfment, no sooner ced than done.

Conradt B.

Dev Cell. 2001 Oct;1(4):445-7.

49.

Programmed cell death and its regulation and initiation in C. elegans.

Conradt B.

Ernst Schering Res Found Workshop. 2000;(29):35-55. Review. No abstract available.

PMID:
10943303
50.

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death.

Chen F, Hersh BM, Conradt B, Zhou Z, Riemer D, Gruenbaum Y, Horvitz HR.

Science. 2000 Feb 25;287(5457):1485-9.

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