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Items: 1 to 50 of 154

1.

Transaxillary transcatheter aortic valve implantation utilizing a novel vascular closure device with resorbable collagen material: a feasibility study.

Schaefer A, Schirmer J, Schofer N, Schneeberger Y, Deuschl F, Blankenberg S, Reichenspurner H, Conradi L, Schäfer U.

Clin Res Cardiol. 2018 Dec 17. doi: 10.1007/s00392-018-1407-z. [Epub ahead of print]

PMID:
30560381
2.

Prosthesis-Patient Mismatch after Transcatheter Aortic Valve Implantation: Prevalence and Prognostic Impact under Consideration of Baseline Left Ventricular Function.

Schofer N, Deuschl F, Rübsamen N, Skibowski J, Seiffert M, Voigtländer L, Schaefer A, Schneeberger Y, Schirmer J, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U.

EuroIntervention. 2018 Nov 13. pii: EIJ-D-18-00827. doi: 10.4244/EIJ-D-18-00827. [Epub ahead of print]

3.

Transcatheter aortic valve implantation utilizing a non-occlusive balloon for predilatation.

Schneeberger Y, Schaefer A, Schofer N, Silaschi M, Deuschl F, Blankenberg S, Reichenspurner H, Treede H, Schäfer U, Charitos EI, Conradi L.

Int J Cardiol. 2019 Jan 15;275:65-69. doi: 10.1016/j.ijcard.2018.10.059. Epub 2018 Oct 18.

PMID:
30366854
4.

EndoDB: a database of endothelial cell transcriptomics data.

Khan S, Taverna F, Rohlenova K, Treps L, Geldhof V, de Rooij L, Sokol L, Pircher A, Conradi LC, Kalucka J, Schoonjans L, Eelen G, Dewerchin M, Karakach T, Li X, Goveia J, Carmeliet P.

Nucleic Acids Res. 2019 Jan 8;47(D1):D736-D744. doi: 10.1093/nar/gky997.

5.

Transcatheter Mitral Valve Replacement in Patients With Previous Aortic Valve Replacement.

Cheung A, Webb J, Schaefer U, Moss R, Deuschl FG, Conradi L, Denti P, Latib A, Kiaii B, Bagur R, Ferrari E, Moccetti M, Biasco L, Blanke P, Ben-Gal Y, Banai S.

Circ Cardiovasc Interv. 2018 Oct;11(10):e006412. doi: 10.1161/CIRCINTERVENTIONS.118.006412.

PMID:
30354628
6.

Valve-in-valve-in-valve: Balloon expandable transcatheter heart valve in failing self-expandable transcatheter heart valve in deteriorated surgical bioprosthesis.

Schaefer A, Deuschl F, Conradi L, Schäfer U.

Catheter Cardiovasc Interv. 2018 Dec 1;92(7):E481-E485. doi: 10.1002/ccd.27797. Epub 2018 Sep 9.

PMID:
30196560
7.

FGFR3 mRNA overexpression defines a subset of oligometastatic colorectal cancers with worse prognosis.

Fromme JE, Schmitz K, Wachter A, Grzelinski M, Zielinski D, Koppel C, Conradi LC, Homayounfar K, Hugo T, Hugo S, Lukat L, Rüschoff J, Ströbel P, Ghadimi M, Beißbarth T, Reuter-Jessen K, Bleckmann A, Schildhaus HU.

Oncotarget. 2018 Aug 14;9(63):32204-32218. doi: 10.18632/oncotarget.25941. eCollection 2018 Aug 14.

8.

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.

Kalucka J, Bierhansl L, Conchinha NV, Missiaen R, Elia I, Brüning U, Scheinok S, Treps L, Cantelmo AR, Dubois C, de Zeeuw P, Goveia J, Zecchin A, Taverna F, Morales-Rodriguez F, Brajic A, Conradi LC, Schoors S, Harjes U, Vriens K, Pilz GA, Chen R, Cubbon R, Thienpont B, Cruys B, Wong BW, Ghesquière B, Dewerchin M, De Bock K, Sagaert X, Jessberger S, Jones EAV, Gallez B, Lambrechts D, Mazzone M, Eelen G, Li X, Fendt SM, Carmeliet P.

Cell Metab. 2018 Dec 4;28(6):881-894.e13. doi: 10.1016/j.cmet.2018.07.016. Epub 2018 Aug 23.

PMID:
30146488
9.

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.

Bruning U, Morales-Rodriguez F, Kalucka J, Goveia J, Taverna F, Queiroz KCS, Dubois C, Cantelmo AR, Chen R, Loroch S, Timmerman E, Caixeta V, Bloch K, Conradi LC, Treps L, Staes A, Gevaert K, Tee A, Dewerchin M, Semenkovich CF, Impens F, Schilling B, Verdin E, Swinnen JV, Meier JL, Kulkarni RA, Sickmann A, Ghesquière B, Schoonjans L, Li X, Mazzone M, Carmeliet P.

Cell Metab. 2018 Dec 4;28(6):866-880.e15. doi: 10.1016/j.cmet.2018.07.019. Epub 2018 Aug 23.

PMID:
30146486
10.

Insights from eight years of adoption experience of transcatheter mitral valve repair in Germany: observed utilisation patterns and impact on overall mitral valve procedure volumes.

Schaefer A, Lubos E, Pietzsch JB, Pietzsch M, Weber S, Blankenberg S, Reichenspurner H, Schäfer U, Conradi L.

EuroIntervention. 2018 Oct 12;14(9):e981-e987. doi: 10.4244/EIJ-D-18-00403.

11.

Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion.

Schulz-Heddergott R, Stark N, Edmunds SJ, Li J, Conradi LC, Bohnenberger H, Ceteci F, Greten FR, Dobbelstein M, Moll UM.

Cancer Cell. 2018 Aug 13;34(2):298-314.e7. doi: 10.1016/j.ccell.2018.07.004.

PMID:
30107178
12.

Outcomes with a latest generation self-expandable, intra-annular, re-sheathable transcatheter heart valve system: analysis of patients with impaired left ventricular function and determinants for pacemaker implantation.

Schaefer A, Neumann N, Linder M, Schofer N, Schneeberger Y, Deuschl F, Schoen G, Blankenberg S, Reichenspurner H, Conradi L, Schäfer U.

Clin Res Cardiol. 2018 Oct;107(10):914-923. doi: 10.1007/s00392-018-1263-x. Epub 2018 Apr 28.

PMID:
29705866
13.

Predictors of paravalvular regurgitation and permanent pacemaker implantation after TAVR with a next-generation self-expanding device.

Mauri V, Deuschl F, Frohn T, Schofer N, Linder M, Kuhn E, Schaefer A, Rudolph V, Madershahian N, Conradi L, Rudolph TK, Schäfer U.

Clin Res Cardiol. 2018 Aug;107(8):688-697. doi: 10.1007/s00392-018-1235-1. Epub 2018 Apr 17.

PMID:
29667013
14.

Off-Pump Coronary Artery Bypass Grafting and Stroke-Exploratory Analysis of the GOPCABE Trial and Methodological Considerations.

Reents W, Zacher M, Boergermann J, Kappert U, Hilker M, Färber G, Albert M, Holzhey D, Conradi L, Riess FC, Veeckman P, Strauch JT, Diegeler A, Böning A.

Thorac Cardiovasc Surg. 2018 Sep;66(6):464-469. doi: 10.1055/s-0038-1636936. Epub 2018 Mar 22.

PMID:
29566406
15.

Prospective multicentre evaluation of a novel, low-profile transapical delivery system for self-expandable transcatheter aortic valve implantation: 6-month outcomes.

Conradi L, Hilker M, Kempfert J, Börgermann J, Treede H, Holzhey DM, Schröfel H, Kim WK, Schaefer U, Walther T.

Eur J Cardiothorac Surg. 2018 Oct 1;54(4):762-767. doi: 10.1093/ejcts/ezy097.

PMID:
29554265
16.

Comparative analysis of balloon- versus mechanically-expandable transcatheter heart valves considering landing zone calcification.

Schofer N, Deuschl F, Schön G, Seiffert M, Linder M, Schaefer A, Schirmer J, Lubos E, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U.

J Cardiol. 2018 Jun;71(6):540-546. doi: 10.1016/j.jjcc.2017.09.014. Epub 2018 Mar 13.

PMID:
29548665
17.

RAISEing VEGF-D's importance as predictive biomarker for ramucirumab in metastatic colorectal cancer patients.

Carmeliet P, Li X, Treps L, Conradi LC, Loges S.

Ann Oncol. 2018 Mar 1;29(3):527-529. doi: 10.1093/annonc/mdy028. No abstract available.

PMID:
29360914
18.

First-in-human implantation of a novel self-expanding supra-annular transcatheter heart valve for transcatheter aortic valve implantation inside a small degenerated aortic surgical bioprosthesis.

Schäfer U, Kalbacher D, Voigtländer L, Conradi L.

Catheter Cardiovasc Interv. 2018 Dec 1;92(7):1453-1457. doi: 10.1002/ccd.27466. Epub 2018 Jan 23.

PMID:
29359506
19.

In vitro hydrodynamic and acute clinical performance of a novel self-expanding transcatheter heart valve in various surgical bioprostheses.

Sedaghat A, Sinning JM, Werner N, Nickenig G, Conradi L, Toggweiler S, Schäfer U.

EuroIntervention. 2018 Apr 20;13(17):2014-2017. doi: 10.4244/EIJ-D-17-00844. No abstract available.

20.

The JUPITER registry: One-year outcomes of transapical aortic valve implantation using a second generation transcatheter heart valve for aortic regurgitation.

Silaschi M, Conradi L, Wendler O, Schlingloff F, Kappert U, Rastan AJ, Baumbach H, Holzhey D, Eichinger W, Bader R, Treede H.

Catheter Cardiovasc Interv. 2018 Jun;91(7):1345-1351. doi: 10.1002/ccd.27370. Epub 2017 Nov 24.

PMID:
29171730
21.

Minimally Invasive Mitral Valve Annuloplasty With Realignment of Both Papillary Muscles for Correction of Type IIIb Functional Mitral Regurgitation.

Girdauskas E, Conradi L, Harmel EK, Reichenspurner H.

Innovations (Phila). 2017 Sep/Oct;12(5):329-332. doi: 10.1097/IMI.0000000000000402.

PMID:
28991057
22.

Short-Term Outcome and Hemodynamic Performance of Next-Generation Self-Expanding Versus Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annulus: A Multicenter Propensity-Matched Comparison.

Mauri V, Kim WK, Abumayyaleh M, Walther T, Moellmann H, Schaefer U, Conradi L, Hengstenberg C, Hilker M, Wahlers T, Baldus S, Rudolph V, Madershahian N, Rudolph TK.

Circ Cardiovasc Interv. 2017 Oct;10(10). pii: e005013. doi: 10.1161/CIRCINTERVENTIONS.117.005013.

PMID:
28951395
23.

Transcatheter Tricuspid Valve-In-Ring and Aortic Valve-In-Valve Implantation.

Reichart D, Schofer N, Deuschl F, Schaefer A, Blankenberg S, Reichenspurner H, Schaefer U, Conradi L.

Thorac Cardiovasc Surg Rep. 2017 Jan;6(1):e29-e31. doi: 10.1055/s-0037-1606345. Epub 2017 Sep 18.

24.

Tumor vessel disintegration by maximum tolerable PFKFB3 blockade.

Conradi LC, Brajic A, Cantelmo AR, Bouché A, Kalucka J, Pircher A, Brüning U, Teuwen LA, Vinckier S, Ghesquière B, Dewerchin M, Carmeliet P.

Angiogenesis. 2017 Nov;20(4):599-613. doi: 10.1007/s10456-017-9573-6. Epub 2017 Sep 5.

PMID:
28875379
25.

First-in-human implantation of a novel transfemoral selfexpanding transcatheter heart valve to treat pure aortic regurgitation.

Schäfer U, Schirmer J, Niklas S, Harmel E, Deuschl F, Conradi L.

EuroIntervention. 2017 Dec 20;13(11):1296-1299. doi: 10.4244/EIJ-D-17-00502.

26.

Transcatheter Mitral Valve Replacement for Degenerated Bioprosthetic Valves and Failed Annuloplasty Rings.

Yoon SH, Whisenant BK, Bleiziffer S, Delgado V, Schofer N, Eschenbach L, Fujita B, Sharma R, Ancona M, Yzeiraj E, Cannata S, Barker C, Davies JE, Frangieh AH, Deuschl F, Podlesnikar T, Asami M, Dhoble A, Chyou A, Masson JB, Wijeysundera HC, Blackman DJ, Rampat R, Taramasso M, Gutierrez-Ibanes E, Chakravarty T, Attizzani GF, Kaneko T, Wong SC, Sievert H, Nietlispach F, Hildick-Smith D, Nombela-Franco L, Conradi L, Hengstenberg C, Reardon MJ, Kasel AM, Redwood S, Colombo A, Kar S, Maisano F, Windecker S, Pilgrim T, Ensminger SM, Prendergast BD, Schofer J, Schaefer U, Bax JJ, Latib A, Makkar RR.

J Am Coll Cardiol. 2017 Aug 29;70(9):1121-1131. doi: 10.1016/j.jacc.2017.07.714.

27.

Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death.

Oberthür R, Seemann H, Gehrig J, Rave-Fränk M, Bremmer F, Halpape R, Conradi LC, Scharf JG, Burfeind P, Kaulfuß S.

Cancer Lett. 2017 Oct 28;407:93-105. doi: 10.1016/j.canlet.2017.08.009. Epub 2017 Aug 18.

PMID:
28823963
28.

The utilization of multidisciplinary tumor boards (MDT) in clinical routine: results of a health care research study focusing on patients with metastasized colorectal cancer.

Lowes M, Kleiss M, Lueck R, Detken S, Koenig A, Nietert M, Beissbarth T, Stanek K, Langer C, Ghadimi M, Conradi LC, Homayounfar K.

Int J Colorectal Dis. 2017 Oct;32(10):1463-1469. doi: 10.1007/s00384-017-2871-z. Epub 2017 Aug 5.

29.

Comparison of latest generation transfemoral self-expandable and balloon-expandable transcatheter heart valves.

Schaefer A, Linder M, Seiffert M, Schoen G, Deuschl F, Schofer N, Schneeberger Y, Blankenberg S, Reichenspurner H, Schaefer U, Conradi L.

Interact Cardiovasc Thorac Surg. 2017 Dec 1;25(6):905-911. doi: 10.1093/icvts/ivx194.

PMID:
28655156
30.

Structural Valve Deterioration of a Subcoronary Implanted Stentless Bioprosthesis: How to Treat?

Harmel EK, Conradi L, Schäfer U, Deuschl F, Schofer N, Blankenberg S, Reichenspurner H, Girdauskas E.

Ann Thorac Surg. 2017 Jul;104(1):e53-e55. doi: 10.1016/j.athoracsur.2017.01.109.

PMID:
28633263
31.

The Prognostic Value of Tyrosine Kinase SRC Expression in Locally Advanced Rectal Cancer.

Rühlmann F, Nietert M, Sprenger T, Wolff HA, Homayounfar K, Middel P, Bohnenberger H, Beissbarth T, Ghadimi BM, Liersch T, Conradi LC.

J Cancer. 2017 Apr 10;8(7):1229-1237. doi: 10.7150/jca.16980. eCollection 2017.

32.

Uncommon cause of pulmonary hypertension.

Petersen J, Pecha S, Neumann N, Conradi L, Reichenspurner H, Girdauskas E.

J Card Surg. 2017 Jun;32(6):366-367. doi: 10.1111/jocs.13144. Epub 2017 May 11. No abstract available.

PMID:
28497527
33.

First experience with transfemoral transcatheter aortic valve implantation without prior balloon pre-dilatation using a latest generation repositionable and retrievable transcatheter heart valve†.

Schaefer A, Harmel E, Seiffert M, Reichart D, Deuschl F, Schofer N, Schneeberger Y, Blankenberg S, Reichenspurner H, Schaefer U, Conradi L.

Interact Cardiovasc Thorac Surg. 2017 May 1;24(5):659-662. doi: 10.1093/icvts/ivw446.

PMID:
28329312
34.

Direct percutaneous transaxillary implantation of a novel self-expandable transcatheter heart valve for aortic stenosis.

Deuschl F, Schofer N, Seiffert M, Hakmi S, Mizote I, Schaefer A, Schirmer J, Reichenspurner H, Blankenberg S, Conradi L, Schäfer U.

Catheter Cardiovasc Interv. 2017 Dec 1;90(7):1167-1174. doi: 10.1002/ccd.26986. Epub 2017 Mar 15.

PMID:
28296065
35.

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease.

Bierhansl L, Conradi LC, Treps L, Dewerchin M, Carmeliet P.

Physiology (Bethesda). 2017 Mar;32(2):126-140. doi: 10.1152/physiol.00031.2016. Review.

36.

Safety and efficacy of the percutaneous transaxillary access for transcatheter aortic valve implantation using various transcatheter heart valves in 100 consecutive patients.

Schäfer U, Deuschl F, Schofer N, Frerker C, Schmidt T, Kuck KH, Kreidel F, Schirmer J, Mizote I, Reichenspurner H, Blankenberg S, Treede H, Conradi L.

Int J Cardiol. 2017 Apr 1;232:247-254. doi: 10.1016/j.ijcard.2017.01.010. Epub 2017 Jan 7.

PMID:
28118931
37.

Minimally invasive endoscopic surgery versus catheter-based device occlusion for atrial septal defects in adults: reconsideration of the standard of care.

Schneeberger Y, Schaefer A, Conradi L, Brickwedel J, Reichenspurner H, Kozlik-Feldmann R, Detter C.

Interact Cardiovasc Thorac Surg. 2017 Apr 1;24(4):603-608. doi: 10.1093/icvts/ivw366.

PMID:
28040751
38.

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.

Cantelmo AR, Conradi LC, Brajic A, Goveia J, Kalucka J, Pircher A, Chaturvedi P, Hol J, Thienpont B, Teuwen LA, Schoors S, Boeckx B, Vriens J, Kuchnio A, Veys K, Cruys B, Finotto L, Treps L, Stav-Noraas TE, Bifari F, Stapor P, Decimo I, Kampen K, De Bock K, Haraldsen G, Schoonjans L, Rabelink T, Eelen G, Ghesquière B, Rehman J, Lambrechts D, Malik AB, Dewerchin M, Carmeliet P.

Cancer Cell. 2016 Dec 12;30(6):968-985. doi: 10.1016/j.ccell.2016.10.006. Epub 2016 Nov 17.

39.

Repeated adjuvant anti-CEA radioimmunotherapy after resection of colorectal liver metastases: Safety, feasibility, and long-term efficacy results of a prospective phase 2 study.

Sahlmann CO, Homayounfar K, Niessner M, Dyczkowski J, Conradi LC, Braulke F, Meller B, Beißbarth T, Ghadimi BM, Meller J, Goldenberg DM, Liersch T.

Cancer. 2017 Feb 15;123(4):638-649. doi: 10.1002/cncr.30390. Epub 2016 Oct 20.

40.

Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies.

Jo P, Nietert M, Gusky L, Kitz J, Conradi LC, Müller-Dornieden A, Schüler P, Wolff HA, Rüschoff J, Ströbel P, Grade M, Liersch T, Beißbarth T, Ghadimi MB, Sax U, Gaedcke J.

Sci Rep. 2016 Oct 18;6:35589. doi: 10.1038/srep35589.

41.

Transcatheter valve-in-valve implantation versus redo surgical aortic valve replacement in patients with failed aortic bioprostheses.

Silaschi M, Wendler O, Seiffert M, Castro L, Lubos E, Schirmer J, Blankenberg S, Reichenspurner H, Schäfer U, Treede H, MacCarthy P, Conradi L.

Interact Cardiovasc Thorac Surg. 2017 Jan;24(1):63-70. doi: 10.1093/icvts/ivw300. Epub 2016 Sep 13.

PMID:
27624351
42.

Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities.

Goveia J, Pircher A, Conradi LC, Kalucka J, Lagani V, Dewerchin M, Eelen G, DeBerardinis RJ, Wilson ID, Carmeliet P.

EMBO Mol Med. 2016 Oct 4;8(10):1134-1142. doi: 10.15252/emmm.201606798. Print 2016 Oct.

43.

Glycolytic regulation of cell rearrangement in angiogenesis.

Cruys B, Wong BW, Kuchnio A, Verdegem D, Cantelmo AR, Conradi LC, Vandekeere S, Bouché A, Cornelissen I, Vinckier S, Merks RM, Dejana E, Gerhardt H, Dewerchin M, Bentley K, Carmeliet P.

Nat Commun. 2016 Jul 20;7:12240. doi: 10.1038/ncomms12240.

44.

Subannular perforation of left ventricular outflow tract associated with transcatheter valve implantation: pathophysiological background and clinical implications.

Girdauskas E, Owais T, Fey B, Kuntze F, Lauer B, Borger MA, Conradi L, Reichenspurner H, Kuntze T.

Eur J Cardiothorac Surg. 2017 Jan;51(1):91-96. doi: 10.1093/ejcts/ezw252. Epub 2016 Jul 13.

PMID:
27412343
45.

Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers-A New Perspective?

Treps L, Conradi LC, Harjes U, Carmeliet P.

Pharmacol Rev. 2016 Jul;68(3):872-87. doi: 10.1124/pr.116.012492. Review.

46.

A matched pairs analysis of non-rib-spreading, fully endoscopic, mini-incision technique versus conventional mini-thoracotomy for mitral valve repair.

Westhofen S, Conradi L, Deuse T, Detter C, Vettorazzi E, Treede H, Reichenspurner H.

Eur J Cardiothorac Surg. 2016 Dec;50(6):1181-1187. doi: 10.1093/ejcts/ezw184. Epub 2016 Jun 3.

PMID:
27261077
47.

The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy.

Naito S, Hillebrand M, Bernhardt AMJ, Jagodzinski A, Conradi L, Detter C, Sydow K, Reichenspurner H, Kodolitsch YV, Girdauskas E.

Thorac Cardiovasc Surg. 2018 Jun;66(4):278-286. doi: 10.1055/s-0036-1583525. Epub 2016 May 5. Review.

PMID:
27148933
48.

A case of anomalous left coronary artery obstruction caused by lotus valve implantation.

Mizote I, Conradi L, Schäfer U.

Catheter Cardiovasc Interv. 2017 Dec 1;90(7):1227-1231. doi: 10.1002/ccd.26541. Epub 2016 May 3.

PMID:
27143415
49.

Baseline anemia and its impact on midterm outcome after transcatheter aortic valve implantation.

Seiffert M, Conradi L, Gutwein A, Schön G, Deuschl F, Schofer N, Becker N, Schirmer J, Reichenspurner H, Blankenberg S, Treede H, Schäfer U.

Catheter Cardiovasc Interv. 2017 Jan;89(1):E44-E52. doi: 10.1002/ccd.26563. Epub 2016 May 3.

PMID:
27142257
50.

[Lymph node metastases in ypT1/2 rectal cancer after neoadjuvant chemoradiotherapy : The Achilles heel of organ-preserving operative procedures?].

Sprenger T, Rothe H, Beissbarth T, Conradi LC, Kauffels A, Homayounfar K, Behnes CL, Rödel C, Liersch T, Ghadimi M.

Chirurg. 2016 Jul;87(7):593-601. doi: 10.1007/s00104-016-0170-9. German.

PMID:
27106241

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