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Long-term patient-reported outcomes after laparoscopic Burch colposuspension.

Conrad DH, Pacquee S, Saar TD, Walsh C, Chou D, Rosen D, Cario GM.

Aust N Z J Obstet Gynaecol. 2019 Sep 12. doi: 10.1111/ajo.13048. [Epub ahead of print]


The Il9 CNS-25 Regulatory Element Controls Mast Cell and Basophil IL-9 Production.

Abdul Qayum A, Koh B, Martin RK, Kenworthy BT, Kharwadkar R, Fu Y, Wu W, Conrad DH, Kaplan MH.

J Immunol. 2019 Sep 1;203(5):1111-1121. doi: 10.4049/jimmunol.1900272. Epub 2019 Jul 26.


A new look at IgE beyond allergies.

Luker AJ, Lownik JC, Conrad DH, Martin RK.

F1000Res. 2019 May 24;8. pii: F1000 Faculty Rev-736. doi: 10.12688/f1000research.18186.1. eCollection 2019. Review.


A Disintegrin and Metalloproteinase 17 is required for ILC2 responses to IL-33.

Lownik JC, Conrad DH, Martin RK.

Biochem Biophys Res Commun. 2019 May 14;512(4):723-728. doi: 10.1016/j.bbrc.2019.03.120. Epub 2019 Mar 27.


Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens.

Cockburn CL, Green RS, Damle SR, Martin RK, Ghahrai NN, Colonne PM, Fullerton MS, Conrad DH, Chalfant CE, Voth DE, Rucks EA, Gilk SD, Carlyon JA.

Life Sci Alliance. 2019 Mar 22;2(2). pii: e201800292. doi: 10.26508/lsa.201800292. Print 2019 Apr.


B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis.

Lownik JC, Wimberly JL, Conrad DH, Martin RK.

J Immunol. 2019 Feb 1;202(3):664-674. doi: 10.4049/jimmunol.1801207. Epub 2019 Jan 4.


The Obligate Intracellular Bacterium Orientia tsutsugamushi Targets NLRC5 To Modulate the Major Histocompatibility Complex Class I Pathway.

Rodino KG, Adcox HE, Martin RK, Patel V, Conrad DH, Carlyon JA.

Infect Immun. 2019 Feb 21;87(3). pii: e00876-18. doi: 10.1128/IAI.00876-18. Print 2019 Mar.


IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice.

Wang J, Cheng X, Xiang MX, Alanne-Kinnunen M, Wang JA, Chen H, He A, Sun X, Lin Y, Tang TT, Tu X, Sjöberg S, Sukhova GK, Liao YH, Conrad DH, Yu L, Kawakami T, Kovanen PT, Libby P, Shi GP.

J Clin Invest. 2018 Nov 1;128(11):5184. doi: 10.1172/JCI124107. Epub 2018 Nov 1. No abstract available.


Laparoscopic Myomectomy of a 4.2 kg Fibroid with Assistance of a Minilaparotomy.

Conrad DH, Saar TD, Pacquée S, Sarofim M, Rosen D, Cario G, Chou D.

Gynecol Minim Invasive Ther. 2018 Jul-Sep;7(3):130-132. doi: 10.4103/GMIT.GMIT_13_18. Epub 2018 Aug 23.


Surgical Management of Complete Procidentia in a Female Patient with Bladder Exstrophy-epispadias Complex: Case Report and Literature Review.

Pacquée S, Conrad DH, Saar TD, Rosen D, Cario G, Chou D, Smet ME.

Gynecol Minim Invasive Ther. 2018 Jul-Sep;7(3):127-129. doi: 10.4103/GMIT.GMIT_14_18. Epub 2018 Aug 23.


Endometriosis Involving the Sciatic Nerve: A Case Report of Isolated Endometriosis of the Sciatic Nerve and Review of the Literature.

Saar TD, Pacquée S, Conrad DH, Sarofim M, Rosnay P, Rosen D, Cario G, Chou D.

Gynecol Minim Invasive Ther. 2018 Apr-Jun;7(2):81-85. doi: 10.4103/GMIT.GMIT_24_18. Epub 2018 May 2.


STAT3 suppresses Wnt/β-catenin signaling during the induction phase of primary Myf5+ brown adipogenesis.

Cantwell MT, Farrar JS, Lownik JC, Meier JA, Hyun M, Raje V, Waters MR, Celi FS, Conrad DH, Harris TE, Larner AC.

Cytokine. 2018 Nov;111:434-444. doi: 10.1016/j.cyto.2018.05.023. Epub 2018 Jun 19.


B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade.

Martin RK, Damle SR, Valentine YA, Zellner MP, James BN, Lownik JC, Luker AJ, Davis EH, DeMeules MM, Khandjian LM, Finkelman FD, Urban JF Jr, Conrad DH.

Cell Rep. 2018 Feb 13;22(7):1824-1834. doi: 10.1016/j.celrep.2018.01.048.


ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses.

Lownik JC, Luker AJ, Damle SR, Cooley LF, El Sayed R, Hutloff A, Pitzalis C, Martin RK, El Shikh MEM, Conrad DH.

J Immunol. 2017 Oct 1;199(7):2305-2315. doi: 10.4049/jimmunol.1700833. Epub 2017 Aug 16.


ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production.

Damle SR, Martin RK, Cockburn CL, Lownik JC, Carlyon JA, Smith AD, Conrad DH.

Allergy. 2018 Jan;73(1):125-136. doi: 10.1111/all.13261. Epub 2017 Aug 31.


Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10.

Hammad H, Vanderkerken M, Pouliot P, Deswarte K, Toussaint W, Vergote K, Vandersarren L, Janssens S, Ramou I, Savvides SN, Haigh JJ, Hendriks R, Kopf M, Craessaerts K, de Strooper B, Kearney JF, Conrad DH, Lambrecht BN.

Nat Immunol. 2017 Mar;18(3):313-320. doi: 10.1038/ni.3657. Epub 2017 Jan 9.


Increased Plasma IgE Accelerate Atherosclerosis in Secreted IgM Deficiency.

Tsiantoulas D, Bot I, Ozsvar-Kozma M, Göderle L, Perkmann T, Hartvigsen K, Conrad DH, Kuiper J, Mallat Z, Binder CJ.

Circ Res. 2017 Jan 6;120(1):78-84. doi: 10.1161/CIRCRESAHA.116.309606. Epub 2016 Nov 30.


CD23 can negatively regulate B-cell receptor signaling.

Liu C, Richard K, Wiggins M, Zhu X, Conrad DH, Song W.

Sci Rep. 2016 May 16;6:25629. doi: 10.1038/srep25629.


Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice.

Cooley LF, El Shikh ME, Li W, Keim RC, Zhang Z, Strauss JF, Zhang Z, Conrad DH.

Sci Rep. 2016 May 12;6:25840. doi: 10.1038/srep25840.


Macrophage migration inhibitory factor deficiency enhances immune response to Nippostrongylus brasiliensis.

Damle SR, Martin RK, Cross JV, Conrad DH.

Mucosal Immunol. 2017 Jan;10(1):205-214. doi: 10.1038/mi.2016.29. Epub 2016 Apr 6.


Increased B Cell ADAM10 in Allergic Patients and Th2 Prone Mice.

Cooley LF, Martin RK, Zellner HB, Irani AM, Uram-Tuculescu C, El Shikh ME, Conrad DH.

PLoS One. 2015 May 1;10(5):e0124331. doi: 10.1371/journal.pone.0124331. eCollection 2015.


Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice.

Oyeniran C, Sturgill JL, Hait NC, Huang WC, Avni D, Maceyka M, Newton J, Allegood JC, Montpetit A, Conrad DH, Milstien S, Spiegel S.

J Allergy Clin Immunol. 2015 Oct;136(4):1035-46.e6. doi: 10.1016/j.jaci.2015.02.031. Epub 2015 Apr 2.


Inhibition of CD23-mediated IgE transcytosis suppresses the initiation and development of allergic airway inflammation.

Palaniyandi S, Liu X, Periasamy S, Ma A, Tang J, Jenkins M, Tuo W, Song W, Keegan AD, Conrad DH, Zhu X.

Mucosal Immunol. 2015 Nov;8(6):1262-74. doi: 10.1038/mi.2015.16. Epub 2015 Mar 18.


Antigen transfer from exosomes to dendritic cells as an explanation for the immune enhancement seen by IgE immune complexes.

Martin RK, Brooks KB, Henningsson F, Heyman B, Conrad DH.

PLoS One. 2014 Oct 20;9(10):e110609. doi: 10.1371/journal.pone.0110609. eCollection 2014.


ADAM10 is required for SCF-induced mast cell migration.

Faber TW, Pullen NA, Fernando JF, Kolawole EM, McLeod JJ, Taruselli M, Williams KL, Rivera KO, Barnstein BO, Conrad DH, Ryan JJ.

Cell Immunol. 2014 Jul;290(1):80-8. doi: 10.1016/j.cellimm.2014.05.005. Epub 2014 May 21.


Mast cell histamine promotes the immunoregulatory activity of myeloid-derived suppressor cells.

Martin RK, Saleem SJ, Folgosa L, Zellner HB, Damle SR, Nguyen GK, Ryan JJ, Bear HD, Irani AM, Conrad DH.

J Leukoc Biol. 2014 Jul;96(1):151-9. doi: 10.1189/jlb.5A1213-644R. Epub 2014 Mar 7.


Myeloid-derived suppressor cells enhance IgE-mediated mast cell responses.

Morales JK, Saleem SJ, Martin RK, Saunders BL, Barnstein BO, Faber TW, Pullen NA, Kolawole EM, Brooks KB, Norton SK, Sturgill J, Graham L, Bear HD, Urban JF Jr, Lantz CS, Conrad DH, Ryan JJ.

J Leukoc Biol. 2014 Apr;95(4):643-50. doi: 10.1189/jlb.0913510. Epub 2013 Dec 12.


Disturbed follicular architecture in B cell A disintegrin and metalloproteinase (ADAM)10 knockouts is mediated by compensatory increases in ADAM17 and TNF-α shedding.

Folgosa L, Zellner HB, El Shikh ME, Conrad DH.

J Immunol. 2013 Dec 15;191(12):5951-8. doi: 10.4049/jimmunol.1302042. Epub 2013 Nov 13.


Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathway.

Fernando J, Faber TW, Pullen NA, Falanga YT, Kolawole EM, Oskeritzian CA, Barnstein BO, Bandara G, Li G, Schwartz LB, Spiegel S, Straus DB, Conrad DH, Bunting KD, Ryan JJ.

J Immunol. 2013 Nov 1;191(9):4505-13. doi: 10.4049/jimmunol.1202723. Epub 2013 Sep 25.


Purifying and measuring immunoglobulin E (IgE) and anti-IgE.

Sturgill JL, Conrad DH.

Methods Mol Biol. 2013;1032:121-31. doi: 10.1007/978-1-62703-496-8_9.


Fyn kinase is required for optimal humoral responses.

Chaimowitz NS, Falanga YT, Ryan JJ, Conrad DH.

PLoS One. 2013 Apr 8;8(4):e60640. doi: 10.1371/journal.pone.0060640. Print 2013.


ADAM10 regulates transcription factor expression required for plasma cell function.

Chaimowitz NS, Kang DJ, Dean LM, Conrad DH.

PLoS One. 2012;7(8):e42694. doi: 10.1371/journal.pone.0042694. Epub 2012 Aug 3.


Cutting edge: mast cells critically augment myeloid-derived suppressor cell activity.

Saleem SJ, Martin RK, Morales JK, Sturgill JL, Gibb DR, Graham L, Bear HD, Manjili MH, Ryan JJ, Conrad DH.

J Immunol. 2012 Jul 15;189(2):511-5. doi: 10.4049/jimmunol.1200647. Epub 2012 Jun 15.


Epoxyeicosatrienoic acids are involved in the C(70) fullerene derivative-induced control of allergic asthma.

Norton SK, Wijesinghe DS, Dellinger A, Sturgill J, Zhou Z, Barbour S, Chalfant C, Conrad DH, Kepley CL.

J Allergy Clin Immunol. 2012 Sep;130(3):761-769.e2. doi: 10.1016/j.jaci.2012.04.023. Epub 2012 Jun 2.


Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.

Falanga YT, Chaimowitz NS, Charles N, Finkelman FD, Pullen NA, Barbour S, Dholaria K, Faber T, Kolawole M, Huang B, Odom S, Rivera J, Carlyon J, Conrad DH, Spiegel S, Oskeritzian CA, Ryan JJ.

J Immunol. 2012 May 1;188(9):4360-8. doi: 10.4049/jimmunol.1003223. Epub 2012 Mar 26.


Structure of factor H-binding protein B (FhbB) of the periopathogen, Treponema denticola: insights into progression of periodontal disease.

Miller DP, Bell JK, McDowell JV, Conrad DH, Burgner JW, Héroux A, Marconi RT.

J Biol Chem. 2012 Apr 13;287(16):12715-22. doi: 10.1074/jbc.M112.339721. Epub 2012 Feb 24.


A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects.

Gomez-Arroyo J, Saleem SJ, Mizuno S, Syed AA, Bogaard HJ, Abbate A, Taraseviciene-Stewart L, Sung Y, Kraskauskas D, Farkas D, Conrad DH, Nicolls MR, Voelkel NF.

Am J Physiol Lung Cell Mol Physiol. 2012 May 15;302(10):L977-91. doi: 10.1152/ajplung.00362.2011. Epub 2012 Feb 3. Review.


Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity.

Zuo D, Yu X, Guo C, Yi H, Chen X, Conrad DH, Guo TL, Chen Z, Fisher PB, Subjeck JR, Wang XY.

FASEB J. 2012 Apr;26(4):1493-505. doi: 10.1096/fj.11-197707. Epub 2011 Dec 29.


Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death.

Suzuki M, El-Hage N, Zou S, Hahn YK, Sorrell ME, Sturgill JL, Conrad DH, Knapp PE, Hauser KF.

Mol Neurodegener. 2011 Nov 17;6:78. doi: 10.1186/1750-1326-6-78.


A disintegrin and metalloproteinase 10 regulates antibody production and maintenance of lymphoid architecture.

Chaimowitz NS, Martin RK, Cichy J, Gibb DR, Patil P, Kang DJ, Farnsworth J, Butcher EC, McCright B, Conrad DH.

J Immunol. 2011 Nov 15;187(10):5114-22. doi: 10.4049/jimmunol.1102172. Epub 2011 Oct 12.


Identification and immunological characterization of three potential vaccinogens against Cryptosporidium species.

Manque PA, Tenjo F, Woehlbier U, Lara AM, Serrano MG, Xu P, Alves JM, Smeltz RB, Conrad DH, Buck GA.

Clin Vaccine Immunol. 2011 Nov;18(11):1796-802. doi: 10.1128/CVI.05197-11. Epub 2011 Sep 14.


IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice.

Wang J, Cheng X, Xiang MX, Alanne-Kinnunen M, Wang JA, Chen H, He A, Sun X, Lin Y, Tang TT, Tu X, Sjöberg S, Sukhova GK, Liao YH, Conrad DH, Yu L, Kawakami T, Kovanen PT, Libby P, Shi GP.

J Clin Invest. 2011 Sep;121(9):3564-77. doi: 10.1172/JCI46028. Epub 2011 Aug 8. Erratum in: J Clin Invest. 2018 Nov 1;128(11):5184.


A potential new target for asthma therapy: a disintegrin and metalloprotease 10 (ADAM10) involvement in murine experimental asthma.

Mathews JA, Ford J, Norton S, Kang D, Dellinger A, Gibb DR, Ford AQ, Massay H, Kepley CL, Scherle P, Keegan AD, Conrad DH.

Allergy. 2011 Sep;66(9):1193-200. doi: 10.1111/j.1398-9995.2011.02614.x. Epub 2011 May 10.


Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion.

Saleem SJ, Conrad DH.

Int Immunopharmacol. 2011 Jul;11(7):808-15. doi: 10.1016/j.intimp.2011.03.010. Epub 2011 Mar 21. Review.


ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch.

Gibb DR, Saleem SJ, Kang DJ, Subler MA, Conrad DH.

J Immunol. 2011 Apr 1;186(7):4244-52. doi: 10.4049/jimmunol.1003318. Epub 2011 Mar 2.


CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action.

Schlosburg JE, O'Neal ST, Conrad DH, Lichtman AH.

Psychopharmacology (Berl). 2011 Aug;216(3):323-31. doi: 10.1007/s00213-011-2224-5. Epub 2011 Feb 22.


CD23-dependent transcytosis of IgE and immune complex across the polarized human respiratory epithelial cells.

Palaniyandi S, Tomei E, Li Z, Conrad DH, Zhu X.

J Immunol. 2011 Mar 15;186(6):3484-96. doi: 10.4049/jimmunol.1002146. Epub 2011 Feb 9.


The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity.

Gibb DR, Saleem SJ, Chaimowitz NS, Mathews J, Conrad DH.

Mol Immunol. 2011 Jun;48(11):1319-27. doi: 10.1016/j.molimm.2010.12.005. Epub 2011 Jan 13. Review.


Glutamate signaling through the kainate receptor enhances human immunoglobulin production.

Sturgill JL, Mathews J, Scherle P, Conrad DH.

J Neuroimmunol. 2011 Apr;233(1-2):80-9. doi: 10.1016/j.jneuroim.2010.11.014. Epub 2011 Jan 6.


Regulation of the IgE response.

Conrad DH, Gibb DR, Sturgill J.

F1000 Biol Rep. 2010 Feb 24;2. pii: 14. doi: 10.3410/B2-14.

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