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Items: 42

1.

An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates.

Charvin D, Di Paolo T, Bezard E, Gregoire L, Takano A, Duvey G, Pioli E, Halldin C, Medori R, Conquet F.

Mov Disord. 2018 Oct;33(10):1619-1631. doi: 10.1002/mds.27462. Epub 2018 Sep 14.

PMID:
30216534
2.

Discovery, Structure-Activity Relationship, and Antiparkinsonian Effect of a Potent and Brain-Penetrant Chemical Series of Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4.

Charvin D, Pomel V, Ortiz M, Frauli M, Scheffler S, Steinberg E, Baron L, Deshons L, Rudigier R, Thiarc D, Morice C, Manteau B, Mayer S, Graham D, Giethlen B, Brugger N, Hédou G, Conquet F, Schann S.

J Med Chem. 2017 Oct 26;60(20):8515-8537. doi: 10.1021/acs.jmedchem.7b00991. Epub 2017 Oct 12.

PMID:
28902994
3.

Guidepost neurons for the lateral olfactory tract: expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons.

Hirata T, Kumada T, Kawasaki T, Furukawa T, Aiba A, Conquet F, Saga Y, Fukuda A.

Dev Neurobiol. 2012 Dec;72(12):1559-76. doi: 10.1002/dneu.22030. Epub 2012 Jul 20.

4.

Up-regulation of P2X4 receptors in spinal microglia after peripheral nerve injury mediates BDNF release and neuropathic pain.

Ulmann L, Hatcher JP, Hughes JP, Chaumont S, Green PJ, Conquet F, Buell GN, Reeve AJ, Chessell IP, Rassendren F.

J Neurosci. 2008 Oct 29;28(44):11263-8. doi: 10.1523/JNEUROSCI.2308-08.2008.

5.

An analysis of the stimulus requirements for setting the molecular switch reveals a lower threshold for metaplasticity than synaptic plasticity.

Bortolotto ZA, Collett VJ, Conquet F, Jia Z, Collingridge GL.

Neuropharmacology. 2008 Sep;55(4):454-8. doi: 10.1016/j.neuropharm.2008.06.020. Epub 2008 Jun 19.

PMID:
18606173
6.

The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors.

Bortolotto ZA, Collett VJ, Conquet F, Jia Z, van der Putten H, Collingridge GL.

Neuropharmacology. 2005;49 Suppl 1:13-25.

PMID:
16024054
7.

Regulation of main olfactory bulb mitral cell excitability by metabotropic glutamate receptor mGluR1.

Heinbockel T, Heyward P, Conquet F, Ennis M.

J Neurophysiol. 2004 Nov;92(5):3085-96. Epub 2004 Jun 22.

8.

Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.

Brody SA, Dulawa SC, Conquet F, Geyer MA.

Mol Psychiatry. 2004 Jan;9(1):35-41.

PMID:
14699440
9.

Disruption of prepulse inhibition in mice lacking mGluR1.

Brody SA, Conquet F, Geyer MA.

Eur J Neurosci. 2003 Dec;18(12):3361-6.

PMID:
14686909
10.

Synapse-specific mGluR1-dependent long-term potentiation in interneurones regulates mouse hippocampal inhibition.

Lapointe V, Morin F, Ratté S, Croce A, Conquet F, Lacaille JC.

J Physiol. 2004 Feb 15;555(Pt 1):125-35. Epub 2003 Dec 12.

11.

Effect of antipsychotic treatment on the prepulse inhibition deficit of mGluR5 knockout mice.

Brody SA, Conquet F, Geyer MA.

Psychopharmacology (Berl). 2004 Mar;172(2):187-95. Epub 2003 Nov 13.

PMID:
14615875
14.

Corticostriatal LTP requires combined mGluR1 and mGluR5 activation.

Gubellini P, Saulle E, Centonze D, Costa C, Tropepi D, Bernardi G, Conquet F, Calabresi P.

Neuropharmacology. 2003 Jan;44(1):8-16.

PMID:
12559117
15.

Activation of group I mGluRs elicits different responses in murine CA1 and CA3 pyramidal cells.

Chuang SC, Zhao W, Young SR, Conquet F, Bianchi R, Wong RK.

J Physiol. 2002 May 15;541(Pt 1):113-21.

17.

Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

Pisani A, Gubellini P, Bonsi P, Conquet F, Picconi B, Centonze D, Bernardi G, Calabresi P.

Neuroscience. 2001;106(3):579-87.

PMID:
11591458
19.

Activation of metabotropic glutamate receptor subtype 1/protein kinase C/mitogen-activated protein kinase pathway is required for postischemic long-term potentiation in the striatum.

Calabresi P, Saulle E, Marfia GA, Centonze D, Mulloy R, Picconi B, Hipskind RA, Conquet F, Bernardi G.

Mol Pharmacol. 2001 Oct;60(4):808-15.

PMID:
11562444
20.

Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice.

Chiamulera C, Epping-Jordan MP, Zocchi A, Marcon C, Cottiny C, Tacconi S, Corsi M, Orzi F, Conquet F.

Nat Neurosci. 2001 Sep;4(9):873-4.

PMID:
11528416
21.

Selective involvement of mGlu1 receptors in corticostriatal LTD.

Gubellini P, Saulle E, Centonze D, Bonsi P, Pisani A, Bernardi G, Conquet F, Calabresi P.

Neuropharmacology. 2001 Jun;40(7):839-46.

PMID:
11378154
22.

A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock.

Chvatchko Y, Hoogewerf AJ, Meyer A, Alouani S, Juillard P, Buser R, Conquet F, Proudfoot AE, Wells TN, Power CA.

J Exp Med. 2000 May 15;191(10):1755-64.

23.

Immunolocalization of the mGluR1b splice variant of the metabotropic glutamate receptor 1 at parallel fiber-Purkinje cell synapses in the rat cerebellar cortex.

Mateos JM, Benítez R, Elezgarai I, Azkue JJ, Lázaro E, Osorio A, Bilbao A, Doñate F, Sarría R, Conquet F, Ferraguti F, Kuhn R, Knöpfel T, Grandes P.

J Neurochem. 2000 Mar;74(3):1301-9.

24.
25.

Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro.

McCaffery B, Cho K, Bortolotto ZA, Aggleton JP, Brown MW, Conquet F, Collingridge GL, Bashir ZI.

Neuroscience. 1999;93(3):977-84.

PMID:
10473262
26.

Inositol-1,4,5-trisphosphate-mediated rescue of cerebellar long-term depression in subtype 1 metabotropic glutamate receptor mutant mouse.

Daniel H, Levenes C, Fagni L, Conquet F, Bockaert J, Crepel F.

Neuroscience. 1999;92(1):1-6.

PMID:
10392825
27.

The metabotropic glutamate receptor 1 is not involved in the facilitation of glutamate release in cerebrocortical nerve terminals.

Sistiaga A, Herrero I, Conquet F, Sánchez-Prieto J.

Neuropharmacology. 1998 Dec;37(12):1485-92.

PMID:
9886671
28.
29.

Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice.

André E, Conquet F, Steinmayr M, Stratton SC, Porciatti V, Becker-André M.

EMBO J. 1998 Jul 15;17(14):3867-77.

30.

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

Steinmayr M, André E, Conquet F, Rondi-Reig L, Delhaye-Bouchaud N, Auclair N, Daniel H, Crépel F, Mariani J, Sotelo C, Becker-André M.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3960-5.

31.

Immunocytochemical localization of the mGluR1b metabotropic glutamate receptor in the rat hypothalamus.

Mateos JM, Azkue J, Benítez R, Sarría R, Losada J, Conquet F, Ferraguti F, Kuhn R, Knöpfel T, Grandes P.

J Comp Neurol. 1998 Jan 12;390(2):225-33.

PMID:
9453666
32.

The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior.

Lopez-Molina L, Conquet F, Dubois-Dauphin M, Schibler U.

EMBO J. 1997 Nov 17;16(22):6762-71.

33.

Evidence against a permissive role of the metabotropic glutamate receptor 1 in acute excitotoxicity.

Ferraguti F, Pietra C, Valerio E, Corti C, Chiamulera C, Conquet F.

Neuroscience. 1997 Jul;79(1):1-5.

PMID:
9178862
34.

Regulation of synaptic plasticity by mGluR1 studied in vivo in mGluR1 mutant mice.

Bordi F, Reggiani A, Conquet F.

Brain Res. 1997 Jun 27;761(1):121-6.

PMID:
9247074
35.

Incomplete regression of multiple climbing fibre innervation of cerebellar Purkinje cells in mGLuR1 mutant mice.

Levenes C, Daniel H, Jaillard D, Conquet F, Crépel F.

Neuroreport. 1997 Jan 20;8(2):571-4.

PMID:
9080450
36.

mGluR1 mutant mice as a tool to study calcium signalling and multiple innervation in the cerebellum.

Daniel H, Levenes C, Conquet F, Crépel F.

J Physiol Paris. 1996;90(3-4):171-2.

PMID:
9116662
37.
38.

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

Conquet F, Bashir ZI, Davies CH, Daniel H, Ferraguti F, Bordi F, Franz-Bacon K, Reggiani A, Matarese V, Condé F, et al.

Nature. 1994 Nov 17;372(6503):237-43.

PMID:
7969468
39.

Inhibited gastrulation in mouse embryos overexpressing the leukemia inhibitory factor.

Conquet F, Peyriéras N, Tiret L, Brûlet P.

Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):8195-9.

41.

Role of acidic phosphoproteins in the partial reconstitution of the active 60 S ribosomal subunit.

Lavergne JP, Conquet F, Reboud JP, Reboud AM.

FEBS Lett. 1987 May 25;216(1):83-8.

42.

Partial reassembly of active 60S ribosomal subunits from rat liver following treatment with dimethylmaleic anhydride.

Conquet F, Lavergne JP, Paleologue A, Reboud JP, Reboud AM.

Eur J Biochem. 1987 Feb 16;163(1):15-20.

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