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Items: 1 to 50 of 338

1.

Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms.

Ravi V, Madhankumar AB, Abraham T, Slagle-Webb B, Connor JR.

PLoS One. 2019 Sep 6;14(9):e0221952. doi: 10.1371/journal.pone.0221952. eCollection 2019.

2.

Transferrin and H-ferritin involvement in brain iron acquisition during postnatal development: impact of sex and genotype.

Chiou B, Neely EB, Mcdevitt DS, Simpson IA, Connor JR.

J Neurochem. 2019 Jul 24. doi: 10.1111/jnc.14834. [Epub ahead of print]

PMID:
31339576
3.

Oroxylum indicum (L.) extract protects human neuroblastoma SH‑SY5Y cells against β‑amyloid‑induced cell injury.

Mairuae N, Connor JR, Buranrat B, Lee SY.

Mol Med Rep. 2019 Aug;20(2):1933-1942. doi: 10.3892/mmr.2019.10411. Epub 2019 Jun 21.

PMID:
31257498
4.

Establishing the inter-rater reliability of spinal cord damage manual measurement using magnetic resonance imaging.

Cummins DP, Connor JR, Heller KA, Hubert JS, Kates MJ, Wisniewski KR, Berliner JC, O'Dell DR, Elliott JM, Weber KA 2nd, Smith AC.

Spinal Cord Ser Cases. 2019 Feb 18;5:20. doi: 10.1038/s41394-019-0164-1. eCollection 2019.

PMID:
31240117
5.

Iron uptake at the blood-brain barrier is influenced by sex and genotype.

Wade QW, Chiou B, Connor JR.

Adv Pharmacol. 2019;84:123-145. doi: 10.1016/bs.apha.2019.02.005. Epub 2019 Mar 22.

PMID:
31229168
6.

Iron, Myelin, and the Brain: Neuroimaging Meets Neurobiology.

Möller HE, Bossoni L, Connor JR, Crichton RR, Does MD, Ward RJ, Zecca L, Zucca FA, Ronen I.

Trends Neurosci. 2019 Jun;42(6):384-401. doi: 10.1016/j.tins.2019.03.009. Epub 2019 Apr 29. Review.

PMID:
31047721
7.

Semaphorin4A causes loss of mature oligodendrocytes and demyelination in vivo.

Chiou B, Neely E, Kallianpur A, Connor JR.

J Neuroinflammation. 2019 Feb 8;16(1):28. doi: 10.1186/s12974-019-1420-9.

8.

Exosomes impact survival to radiation exposure in cell line models of nervous system cancer.

Mrowczynski OD, Madhankumar AB, Sundstrom JM, Zhao Y, Kawasawa YI, Slagle-Webb B, Mau C, Payne RA, Rizk EB, Zacharia BE, Connor JR.

Oncotarget. 2018 Nov 16;9(90):36083-36101. doi: 10.18632/oncotarget.26300. eCollection 2018 Nov 16.

9.

Targeting IL-13Rα2 for effective treatment of malignant peripheral nerve sheath tumors in mouse models.

Mrowczynski OD, Payne RA, Bourcier AJ, Mau CY, Slagle-Webb B, Shenoy G, Madhankumar AB, Abramson SB, Wolfe D, Harbaugh KS, Rizk EB, Connor JR.

J Neurosurg. 2018 Nov 1:1-11. doi: 10.3171/2018.7.JNS18284. [Epub ahead of print]

PMID:
30544352
10.

Emerging and Dynamic Biomedical Uses of Ferritin.

Chiou B, Connor JR.

Pharmaceuticals (Basel). 2018 Nov 13;11(4). pii: E124. doi: 10.3390/ph11040124. Review.

11.

Midsagittal tissue bridges are associated with walking ability in incomplete spinal cord injury: A magnetic resonance imaging case series.

O'Dell DR, Weber KA, Berliner JC, Elliott JM, Connor JR, Cummins DP, Heller KA, Hubert JS, Kates MJ, Mendoza KR, Smith AC.

J Spinal Cord Med. 2018 Oct 22:1-4. doi: 10.1080/10790268.2018.1527079. [Epub ahead of print]

PMID:
30346248
12.

Cerebrospinal Fluid Ceruloplasmin, Haptoglobin, and Vascular Endothelial Growth Factor Are Associated with Neurocognitive Impairment in Adults with HIV Infection.

Kallianpur AR, Gittleman H, Letendre S, Ellis R, Barnholtz-Sloan JS, Bush WS, Heaton R, Samuels DC, Franklin DR Jr, Rosario-Cookson D, Clifford DB, Collier AC, Gelman B, Marra CM, McArthur JC, McCutchan JA, Morgello S, Grant I, Simpson D, Connor JR, Hulgan T; CHARTER Study Group.

Mol Neurobiol. 2019 May;56(5):3808-3818. doi: 10.1007/s12035-018-1329-9. Epub 2018 Sep 12.

PMID:
30209774
13.

Exosomes and their implications in central nervous system tumor biology.

Mrowczynski OD, Zacharia BE, Connor JR.

Prog Neurobiol. 2019 Jan;172:71-83. doi: 10.1016/j.pneurobio.2018.06.006. Epub 2018 Jul 9. Review.

PMID:
30003942
14.

Endothelial cells are critical regulators of iron transport in a model of the human blood-brain barrier.

Chiou B, Neal EH, Bowman AB, Lippmann ES, Simpson IA, Connor JR.

J Cereb Blood Flow Metab. 2018 Jun 18:271678X18783372. doi: 10.1177/0271678X18783372. [Epub ahead of print]

PMID:
29911470
15.

Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier.

Chiou B, Neal EH, Bowman AB, Lippmann ES, Simpson IA, Connor JR.

PLoS One. 2018 Jun 11;13(6):e0198775. doi: 10.1371/journal.pone.0198775. eCollection 2018.

16.

Distinct progression pattern of susceptibility MRI in the substantia nigra of Parkinson's patients.

Du G, Lewis MM, Sica C, He L, Connor JR, Kong L, Mailman RB, Huang X.

Mov Disord. 2018 Sep;33(9):1423-1431. doi: 10.1002/mds.27318. Epub 2018 May 14.

17.

Susceptibility MRI captures nigral pathology in patients with parkinsonian syndromes.

Lewis MM, Du G, Baccon J, Snyder AM, Murie B, Cooper F, Stetter C, Kong L, Sica C, Mailman RB, Connor JR, Huang X.

Mov Disord. 2018 Sep;33(9):1432-1439. doi: 10.1002/mds.27381. Epub 2018 May 14.

18.

Involvement of the central somatosensory system in restless legs syndrome: A neuroimaging study.

Lee BY, Kim J, Connor JR, Podskalny GD, Ryu Y, Yang QX.

Neurology. 2018 May 22;90(21):e1834-e1841. doi: 10.1212/WNL.0000000000005562. Epub 2018 Apr 25.

PMID:
29695597
19.

A Possible Role for Platelet-Activating Factor Receptor in Amyotrophic Lateral Sclerosis Treatment.

Briones MRS, Snyder AM, Ferreira RC, Neely EB, Connor JR, Broach JR.

Front Neurol. 2018 Feb 6;9:39. doi: 10.3389/fneur.2018.00039. eCollection 2018.

20.

Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children: an IRLSSG task force report.

Allen RP, Picchietti DL, Auerbach M, Cho YW, Connor JR, Earley CJ, Garcia-Borreguero D, Kotagal S, Manconi M, Ondo W, Ulfberg J, Winkelman JW; International Restless Legs Syndrome Study Group (IRLSSG).

Sleep Med. 2018 Jan;41:27-44. doi: 10.1016/j.sleep.2017.11.1126. Epub 2017 Nov 24.

21.

Dietary lipophilic iron alters amyloidogenesis and microglial morphology in Alzheimer's disease knock-in APP mice.

Peters DG, Pollack AN, Cheng KC, Sun D, Saido T, Haaf MP, Yang QX, Connor JR, Meadowcroft MD.

Metallomics. 2018 Mar 1;10(3):426-443. doi: 10.1039/c8mt00004b. Epub 2018 Feb 9.

PMID:
29424844
22.

The role of HFE genotype in macrophage phenotype.

Nixon AM, Neely E, Simpson IA, Connor JR.

J Neuroinflammation. 2018 Feb 1;15(1):30. doi: 10.1186/s12974-018-1057-0.

23.

Gamma Knife radiosurgery of saccular aneurysms in a rabbit model.

Meadowcroft MD, Cooper TK, Rupprecht S, Wright TC, Neely EE, Ferenci M, Kang W, Yang QX, Harbaugh RE, Connor JR, McInerney J.

J Neurosurg. 2018 Dec 1;129(6):1530-1540. doi: 10.3171/2017.6.JNS17722.

PMID:
29328001
24.

HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity.

Nixon AM, Meadowcroft MD, Neely EB, Snyder AM, Purnell CJ, Wright J, Lamendella R, Nandar W, Huang X, Connor JR.

J Neurochem. 2018 May;145(4):299-311. doi: 10.1111/jnc.14299. Epub 2018 Apr 1.

25.

Tumor targeted delivery of doxorubicin in malignant peripheral nerve sheath tumors.

Madhankumar AB, Mrowczynski OD, Slagle-Webb B, Ravi V, Bourcier AJ, Payne R, Harbaugh KS, Rizk E, Connor JR.

PLoS One. 2018 Jan 5;13(1):e0181529. doi: 10.1371/journal.pone.0181529. eCollection 2018.

26.

CSF ferritin predicts CSF Aβ decline in biomarker-determined Alzheimer's disease.

Connor JR.

J Neurol Neurosurg Psychiatry. 2018 May;89(5):445. doi: 10.1136/jnnp-2017-317050. Epub 2017 Dec 8. No abstract available.

PMID:
29222223
27.

Dietary lipophilic iron accelerates regional brain iron-load in C57BL6 mice.

Peters DG, Purnell CJ, Haaf MP, Yang QX, Connor JR, Meadowcroft MD.

Brain Struct Funct. 2018 Apr;223(3):1519-1536. doi: 10.1007/s00429-017-1565-1. Epub 2017 Nov 22.

PMID:
29168009
28.

Regulatory mechanisms for iron transport across the blood-brain barrier.

Duck KA, Simpson IA, Connor JR.

Biochem Biophys Res Commun. 2017 Dec 9;494(1-2):70-75. doi: 10.1016/j.bbrc.2017.10.083. Epub 2017 Oct 17.

PMID:
29054412
29.

Brain Metal Distribution and Neuro-Inflammatory Profiles after Chronic Vanadium Administration and Withdrawal in Mice.

Folarin OR, Snyder AM, Peters DG, Olopade F, Connor JR, Olopade JO.

Front Neuroanat. 2017 Jul 25;11:58. doi: 10.3389/fnana.2017.00058. eCollection 2017.

30.

Reduced Cerebral White Matter Integrity Assessed by DTI in Cognitively Normal H63D-HFE Polymorphism Carriers.

Meadowcroft MD, Wang J, Purnell CJ, Eslinger PJ, Neely EB, Yang QX, Connor JR.

J Neuroimaging. 2018 Jan;28(1):126-133. doi: 10.1111/jon.12461. Epub 2017 Aug 3.

31.

Interleukin-13 conjugated quantum dots for identification of glioma initiating cells and their extracellular vesicles.

Madhankumar AB, Mrowczynski OD, Patel SR, Weston CL, Zacharia BE, Glantz MJ, Siedlecki CA, Xu LC, Connor JR.

Acta Biomater. 2017 Aug;58:205-213. doi: 10.1016/j.actbio.2017.06.002. Epub 2017 Jun 3.

PMID:
28583903
32.

HFE genotype affects exosome phenotype in cancer.

Mrowczynski OD, Madhankumar AB, Slagle-Webb B, Lee SY, Zacharia BE, Connor JR.

Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):1921-1928. doi: 10.1016/j.bbagen.2017.05.014. Epub 2017 May 17.

PMID:
28527894
33.

The Relationship Between Iron Deficiency Anemia and Sensorineural Hearing Loss in the Pediatric and Adolescent Population.

Schieffer KM, Connor JR, Pawelczyk JA, Sekhar DL.

Am J Audiol. 2017 Jun 13;26(2):155-162. doi: 10.1044/2017_AJA-16-0093.

34.

Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults.

Patton SM, Wang Q, Hulgan T, Connor JR, Jia P, Zhao Z, Letendre SL, Ellis RJ, Bush WS, Samuels DC, Franklin DR, Kaur H, Iudicello J, Grant I, Kallianpur AR.

Fluids Barriers CNS. 2017 Apr 21;14(1):11. doi: 10.1186/s12987-017-0058-1.

35.

Analysis of single nucleotide variants of HFE gene and association to survival in The Cancer Genome Atlas GBM data.

Lee SY, Zhu J, Salzberg AC, Zhang B, Liu DJ, Muscat JE, Langan ST, Connor JR.

PLoS One. 2017 Mar 30;12(3):e0174778. doi: 10.1371/journal.pone.0174778. eCollection 2017.

36.

A role for sex and a common HFE gene variant in brain iron uptake.

Duck KA, Neely EB, Simpson IA, Connor JR.

J Cereb Blood Flow Metab. 2018 Mar;38(3):540-548. doi: 10.1177/0271678X17701949. Epub 2017 Mar 28.

37.

Iron and restless legs syndrome: treatment, genetics and pathophysiology.

Connor JR, Patton SM, Oexle K, Allen RP.

Sleep Med. 2017 Mar;31:61-70. doi: 10.1016/j.sleep.2016.07.028. Epub 2016 Nov 10.

38.

Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain barrier and impairs iron-dependent hippocampal neuron dendrite development.

Bastian TW, Duck KA, Michalopoulos GC, Chen MJ, Liu ZJ, Connor JR, Lanier LM, Sola-Visner MC, Georgieff MK.

J Thromb Haemost. 2017 Mar;15(3):565-574. doi: 10.1111/jth.13602. Epub 2017 Feb 16.

39.

The Deterioration Seen in Myelin Related Morphophysiology in Vanadium Exposed Rats is Partially Protected by Concurrent Iron Deficiency.

Usende IL, Leitner DF, Neely E, Connor JR, Olopade JO.

Niger J Physiol Sci. 2016 Aug 30;31(1):11-22.

PMID:
27574759
40.

Iron uptake and transport across physiological barriers.

Duck KA, Connor JR.

Biometals. 2016 Aug;29(4):573-91. doi: 10.1007/s10534-016-9952-2. Epub 2016 Jul 25. Review.

41.

Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and gray matter iron distribution in Alzheimer's disease frontal cortex.

Hare DJ, Raven EP, Roberts BR, Bogeski M, Portbury SD, McLean CA, Masters CL, Connor JR, Bush AI, Crouch PJ, Doble PA.

Neuroimage. 2016 Aug 15;137:124-131. doi: 10.1016/j.neuroimage.2016.05.057. Epub 2016 May 24.

PMID:
27233149
42.

Statins accelerate disease progression and shorten survival in SOD1(G93A) mice.

Su XW, Nandar W, Neely EB, Simmons Z, Connor JR.

Muscle Nerve. 2016 Aug;54(2):284-91. doi: 10.1002/mus.25048. Epub 2016 May 19.

43.

Increased R2* in the Caudate Nucleus of Asymptomatic Welders.

Lee EY, Flynn MR, Du G, Li Y, Lewis MM, Herring AH, Van Buren E, Van Buren S, Kong L, Fry RC, Snyder AM, Connor JR, Yang QX, Mailman RB, Huang X.

Toxicol Sci. 2016 Apr;150(2):369-77. doi: 10.1093/toxsci/kfw003. Epub 2016 Jan 14.

44.

Reduced white matter MRI transverse relaxation rate in cognitively normal H63D-HFE human carriers and H67D-HFE mice.

Meadowcroft MD, Wang J, Purnell CJ, Peters DG, Eslinger PJ, Neely EB, Gill DJ, Vasavada M, Ali-Rahmani F, Yang QX, Connor JR.

Brain Imaging Behav. 2016 Dec;10(4):1231-1242.

45.

From adaption to death: endoplasmic reticulum stress as a novel target of selective neurodegeneration?

Liu Y, Connor JR.

Neural Regen Res. 2015 Sep;10(9):1397-8. doi: 10.4103/1673-5374.165227. No abstract available.

46.

MRI contrast agent for targeting glioma: interleukin-13 labeled liposome encapsulating gadolinium-DTPA.

Liu X, Madhankumar AB, Miller PA, Duck KA, Hafenstein S, Rizk E, Slagle-Webb B, Sheehan JM, Connor JR, Yang QX.

Neuro Oncol. 2016 May;18(5):691-9. doi: 10.1093/neuonc/nov263. Epub 2015 Oct 31.

47.

Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells.

Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, Hale JS, Hubert CG, Mack SC, Jarrar AM, Karl RT, Rosager AM, Nixon AM, Tesar PJ, Hamerlik P, Kristensen BW, Horbinski C, Connor JR, Fox PL, Lathia JD, Rich JN.

Cancer Cell. 2015 Oct 12;28(4):441-455. doi: 10.1016/j.ccell.2015.09.002.

48.

Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death.

Buranrat B, Connor JR.

Oncol Rep. 2015 Nov;34(5):2790-6. doi: 10.3892/or.2015.4250. Epub 2015 Sep 8.

49.

Synergistic actions of blocking angiopoietin-2 and tumor necrosis factor-α in suppressing remodeling of blood vessels and lymphatics in airway inflammation.

Le CT, Laidlaw G, Morehouse CA, Naiman B, Brohawn P, Mustelin T, Connor JR, McDonald DM.

Am J Pathol. 2015 Nov;185(11):2949-68. doi: 10.1016/j.ajpath.2015.07.010. Epub 2015 Sep 5.

50.

The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin.

Peters DG, Connor JR, Meadowcroft MD.

Neurobiol Dis. 2015 Sep;81:49-65. doi: 10.1016/j.nbd.2015.08.007. Epub 2015 Aug 22. Review.

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