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Items: 1 to 50 of 52

1.

Ischemic preconditioning prevents free radical production and mitochondrial depolarization in small-for-size rat liver grafts.

Rehman H, Connor HD, Ramshesh VK, Theruvath TP, Mason RP, Wright GL, Lemasters JJ, Zhong Z.

Transplantation. 2008 May 15;85(9):1322-31. doi: 10.1097/TP.0b013e31816de302.

PMID:
18475191
2.

L-tryptophan radical cation electron spin resonance studies: connecting solution-derived hyperfine coupling constants with protein spectral interpretations.

Connor HD, Sturgeon BE, Mottley C, Sipe HJ Jr, Mason RP.

J Am Chem Soc. 2008 May 21;130(20):6381-7. doi: 10.1021/ja0780277. Epub 2008 Apr 24.

3.

Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.

Woods CG, Burns AM, Maki A, Bradford BU, Cunningham ML, Connor HD, Kadiiska MB, Mason RP, Peters JM, Rusyn I.

Free Radic Biol Med. 2007 Feb 1;42(3):335-42. Epub 2006 Nov 3.

4.

Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols.

Zhong Z, Connor HD, Li X, Mason RP, Forman DT, Lemasters JJ, Thurman RG.

J Pharm Pharmacol. 2006 Nov;58(11):1533-43.

PMID:
17132217
6.

Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols.

Zhong Z, Connor HD, Froh M, Bunzendahl H, Lind H, Lehnert M, Mason RP, Thurman RG, Lemasters JJ.

Gastroenterology. 2005 Aug;129(2):652-64.

PMID:
16083719
7.

Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats.

Zhong Z, Connor HD, Froh M, Lind H, Bunzendahl H, Mason RP, Thurman RG, Lemasters JJ.

Free Radic Biol Med. 2004 May 15;36(10):1248-58.

PMID:
15110390
8.

Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice.

McKim SE, Gäbele E, Isayama F, Lambert JC, Tucker LM, Wheeler MD, Connor HD, Mason RP, Doll MA, Hein DW, Arteel GE.

Gastroenterology. 2003 Dec;125(6):1834-44.

PMID:
14724835
9.

The CYP inhibitor 1-aminobenzotriazole does not prevent oxidative stress associated with alcohol-induced liver injury in rats and mice.

Isayama F, Froh M, Bradford BU, McKim SE, Kadiiska MB, Connor HD, Mason RP, Koop DR, Wheeler MD, Arteel GE.

Free Radic Biol Med. 2003 Dec 15;35(12):1568-81.

PMID:
14680680
10.

Antioxidant activity of Sempervivum tectorum and its components.

Sentjurc M, Nemec M, Connor HD, Abram V.

J Agric Food Chem. 2003 Apr 23;51(9):2766-71.

PMID:
12696970
11.

Prevention of hepatic ischemia-reperfusion injury by green tea extract.

Zhong Z, Froh M, Connor HD, Li X, Conzelmann LO, Mason RP, Lemasters JJ, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2002 Oct;283(4):G957-64.

12.

Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo.

Yin M, Zhong Z, Connor HD, Bunzendahl H, Finn WF, Rusyn I, Li X, Raleigh JA, Mason RP, Thurman RG.

Am J Physiol Renal Physiol. 2002 Mar;282(3):F417-23.

13.

The role of Kupffer cell oxidant production in early ethanol-induced liver disease.

Wheeler MD, Kono H, Yin M, Nakagami M, Uesugi T, Arteel GE, Gäbele E, Rusyn I, Yamashina S, Froh M, Adachi Y, Iimuro Y, Bradford BU, Smutney OM, Connor HD, Mason RP, Goyert SM, Peters JM, Gonzalez FJ, Samulski RJ, Thurman RG.

Free Radic Biol Med. 2001 Dec 15;31(12):1544-9. Review.

PMID:
11744328
14.

Cu/Zn-superoxide dismutase gene attenuates ischemia-reperfusion injury in the rat kidney.

Yin M, Wheeler MD, Connor HD, Zhong Z, Bunzendahl H, Dikalova A, Samulski RJ, Schoonhoven R, Mason RP, Swenberg JA, Thurman RG.

J Am Soc Nephrol. 2001 Dec;12(12):2691-700.

15.

Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat.

Wheeler MD, Nakagami M, Bradford BU, Uesugi T, Mason RP, Connor HD, Dikalova A, Kadiiska M, Thurman RG.

J Biol Chem. 2001 Sep 28;276(39):36664-72. Epub 2001 Jul 26.

16.

Development of an animal model of chronic alcohol-induced pancreatitis in the rat.

Kono H, Nakagami M, Rusyn I, Connor HD, Stefanovic B, Brenner DA, Mason RP, Arteel GE, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1178-86.

17.

Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat.

Kono H, Rusyn I, Uesugi T, Yamashina S, Connor HD, Dikalova A, Mason RP, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2001 May;280(5):G1005-12.

18.

Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats.

Wheeler MD, Kono H, Yin M, Rusyn I, Froh M, Connor HD, Mason RP, Samulski RJ, Thurman RG.

Gastroenterology. 2001 Apr;120(5):1241-50.

PMID:
11266387
19.

Viral delivery of superoxide dismutase gene reduces cyclosporine A-induced nephrotoxicity.

Zhong Z, Connor HD, Yin M, Wheeler MD, Mason RP, Thurman RG.

Kidney Int. 2001 Apr;59(4):1397-404.

20.

Gene delivery of Cu/Zn-superoxide dismutase improves graft function after transplantation of fatty livers in the rat.

Lehmann TG, Wheeler MD, Schwabe RF, Connor HD, Schoonhoven R, Bunzendahl H, Brenner DA, Jude Samulski R, Zhong Z, Thurman RG.

Hepatology. 2000 Dec;32(6):1255-64.

PMID:
11093732
21.

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

Kono H, Rusyn I, Yin M, Gäbele E, Yamashina S, Dikalova A, Kadiiska MB, Connor HD, Mason RP, Segal BH, Bradford BU, Holland SM, Thurman RG.

J Clin Invest. 2000 Oct;106(7):867-72.

22.

Allopurinol prevents early alcohol-induced liver injury in rats.

Kono H, Rusyn I, Bradford BU, Connor HD, Mason RP, Thurman RG.

J Pharmacol Exp Ther. 2000 Apr;293(1):296-303.

PMID:
10734182
23.

Medium-chain triglycerides inhibit free radical formation and TNF-alpha production in rats given enteral ethanol.

Kono H, Enomoto N, Connor HD, Wheeler MD, Bradford BU, Rivera CA, Kadiiska MB, Mason RP, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2000 Mar;278(3):G467-76.

24.

Glycine improves survival after hemorrhagic shock in the rat.

Zhong Z, Enomoto N, Connor HD, Moss N, Mason RP, Thurman RG.

Shock. 1999 Jul;12(1):54-62.

PMID:
10468052
25.

Dietary glycine and renal denervation prevents cyclosporin A-induced hydroxyl radical production in rat kidney.

Zhong Z, Connor HD, Yin M, Moss N, Mason RP, Bunzendahl H, Forman DT, Thurman RG.

Mol Pharmacol. 1999 Sep;56(3):455-63.

PMID:
10462532
26.

Mechanisms of alcohol-induced hepatotoxicity: studies in rats.

Thurman RG, Bradford BU, Iimuro Y, Frankenberg MV, Knecht KT, Connor HD, Adachi Y, Wall C, Arteel GE, Raleigh JA, Forman DT, Mason RP.

Front Biosci. 1999 Jul 15;4:e42-6. Review.

PMID:
10417060
27.

Binge drinking disturbs hepatic microcirculation after transplantation: prevention with free radical scavengers.

Zhong Z, Arteel GE, Connor HD, Schemmer P, Chou SC, Raleigh JA, Mason RP, Lemasters JJ, Thurman RG.

J Pharmacol Exp Ther. 1999 Aug;290(2):611-20.

PMID:
10411569
28.

Reperfusion injury in livers due to gentle in situ organ manipulation during harvest involves hypoxia and free radicals.

Schemmer P, Connor HD, Arteel GE, Raleigh JA, Bunzendahl H, Mason RP, Thurman RG.

J Pharmacol Exp Ther. 1999 Jul;290(1):235-40.

PMID:
10381781
29.

Ethanol, not fat accumulation per se, increases free radical production in a low-flow, reflow liver perfusion model.

Zhong Z, Connor HD, Mason RP, Lemasters JJ, Thurman RG.

Transplantation. 1998 Dec 15;66(11):1431-8.

PMID:
9869083
30.

The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury.

Thurman RG, Bradford BU, Iimuro Y, Knecht KT, Arteel GE, Yin M, Connor HD, Wall C, Raleigh JA, Frankenberg MV, Adachi Y, Forman DT, Brenner D, Kadiiska M, Mason RP.

J Gastroenterol Hepatol. 1998 Sep;13 Suppl:S39-50. Review.

PMID:
9792033
31.

Generation of lipid free radicals by adherent leukocytes from transplanted rat liver.

Stachlewitz RF, Gao W, Zhong Z, Connor HD, Mason RP, Thurman RG.

Transpl Int. 1998;11(5):353-60.

PMID:
9787411
32.

Cyclosporin A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine.

Zhong Z, Arteel GE, Connor HD, Yin M, Frankenberg MV, Stachlewitz RF, Raleigh JA, Mason RP, Thurman RG.

Am J Physiol. 1998 Oct;275(4):F595-604. doi: 10.1152/ajprenal.1998.275.4.F595.

PMID:
9755131
33.

The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury.

Thurman RG, Bradford BU, Iimuro Y, Knecht KT, Arteel GE, Yin M, Connor HD, Wall C, Raleigh JA, Frankenberg MV, Adachi Y, Forman DT, Brenner D, Kadiiska M, Mason RP.

J Gastroenterol Hepatol. 1998 Sep;13(S1):S39-S50. doi: 10.1111/jgh.1998.13.s1.39.

PMID:
28976690
34.

Clarification of the relationship between free radical spin trapping and carbon tetrachloride metabolism in microsomal systems.

Connor HD, Thurman RG, Chen G, Poyer JL, Janzen EG, Mason RP.

Free Radic Biol Med. 1998 Jun;24(9):1364-8.

PMID:
9641253
35.

Development and characterization of a new model of tacrine-induced hepatotoxicity: role of the sympathetic nervous system and hypoxia-reoxygenation.

Stachlewitz RF, Arteel GE, Raleigh JA, Connor HD, Mason RP, Thurman RG.

J Pharmacol Exp Ther. 1997 Sep;282(3):1591-9.

PMID:
9316876
36.

Role of Kupffer cells, endotoxin and free radicals in hepatotoxicity due to prolonged alcohol consumption: studies in female and male rats.

Thurman RG, Bradford BU, Iimuro Y, Knecht KT, Connor HD, Adachi Y, Wall C, Arteel GE, Raleigh JA, Forman DT, Mason RP.

J Nutr. 1997 May;127(5 Suppl):903S-906S. doi: 10.1093/jn/127.5.903S. Review.

PMID:
9164260
37.

Role of free radicals in failure of fatty livers following liver transplantation and alcoholic liver injury.

Thurman RG, Gao W, Connor HD, Adachi Y, Stachlewitz RF, Zhong Z, Knecht KT, Bradford BU, Mason RP, Lemasters JJ.

Adv Exp Med Biol. 1996;387:231-41. No abstract available.

PMID:
8794217
38.

Role of Kupffer cells in reperfusion injury in fat-loaded livers from ethanol-treated rats.

Zhong Z, Connor HD, Mason RP, Qu W, Gao W, Lemasters JJ, Thurman RG.

J Pharmacol Exp Ther. 1995 Dec;275(3):1512-7.

PMID:
8531123
39.

Primary nonfunction of fatty livers produced by alcohol is associated with a new, antioxidant-insensitive free radical species.

Gao W, Connor HD, Lemasters JJ, Mason RP, Thurman RG.

Transplantation. 1995 Mar 15;59(5):674-9.

PMID:
7886790
40.

Inactivation of Kupffer cells minimizes reperfusion injury in fat-loaded livers from ethanol-treated rats.

Zhong Z, Qu W, Connor HD, Thurman RG.

Transplant Proc. 1995 Feb;27(1):528-30. No abstract available.

PMID:
7879088
41.

Role of Kupffer cells in failure of fatty livers following liver transplantation and alcoholic liver injury.

Thurman RG, Gao W, Connor HD, Adachi Y, Stachlewitz RF, Zhong Z, Knecht KT, Bradford BU, Mason RP, Lemasters JJ.

J Gastroenterol Hepatol. 1995;10 Suppl 1:S24-30.

PMID:
8589336
42.

Role of Kupffer cells in the pathogenesis of hepatic reperfusion injury.

Bremer C, Bradford BU, Hunt KJ, Knecht KT, Connor HD, Mason RP, Thurman RG.

Am J Physiol. 1994 Oct;267(4 Pt 1):G630-6.

PMID:
7943328
43.
44.

SPC-100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat.

Thurman RG, Gao W, Connor HD, Mason RP, Lemasters JJ, Bozigian H, Adams LM.

Transpl Int. 1994;7 Suppl 1:S167-70.

PMID:
11271195
45.
46.
47.

Reaction of glutathione with a free radical metabolite of carbon tetrachloride.

Connor HD, Lacagnin LB, Knecht KT, Thurman RG, Mason RP.

Mol Pharmacol. 1990 Mar;37(3):443-51.

PMID:
2156156
48.

The carbon dioxide anion radical adduct in the perfused rat liver: relationship to halocarbon-induced toxicity.

LaCagnin LB, Connor HD, Mason RP, Thurman RG.

Mol Pharmacol. 1988 Mar;33(3):351-7.

PMID:
2832723
49.

[17O]oxygen hyperfine structure for the hydroxyl and superoxide radical adducts of the spin traps DMPO, PBN and 4-POBN.

Mottley C, Connor HD, Mason RP.

Biochem Biophys Res Commun. 1986 Dec 15;141(2):622-8.

PMID:
3026386
50.

A search for oxygen-centered free radicals in the lipoxygenase/linoleic acid system.

Connor HD, Fischer V, Mason RP.

Biochem Biophys Res Commun. 1986 Dec 15;141(2):614-21.

PMID:
3026385

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