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Descriptive analysis of the economic burden of treatment resistance in a major depressive episode.

Cai Q, Sheehan JJ, Wu B, Alphs L, Connolly N, Benson C.

Curr Med Res Opin. 2019 Oct 10:1-7. doi: 10.1080/03007995.2019.1671087. [Epub ahead of print]


Predictors and Limitations of the Penetration Depth of Photodynamic Effects in the Rodent Brain.

Inglut CT, Gaitan B, Najafali D, Lopez IA, Connolly NP, Orsila S, Perttilä R, Woodworth GF, Chen Y, Huang HC.

Photochem Photobiol. 2019 Aug 23. doi: 10.1111/php.13155. [Epub ahead of print]


GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model.

Liu J, McDaid L, Araque A, Wade J, Harkin J, Karim S, Henshall DC, Connolly NMC, Johnson AP, Tyrrell AM, Timmis J, Millard AG, Hilder J, Halliday DM.

Front Cell Neurosci. 2019 Jul 23;13:335. doi: 10.3389/fncel.2019.00335. eCollection 2019.


An episode level evaluation of the treatment journey of patients with major depressive disorder and treatment-resistant depression.

Wu B, Cai Q, Sheehan JJ, Benson C, Connolly N, Alphs L.

PLoS One. 2019 Aug 8;14(8):e0220763. doi: 10.1371/journal.pone.0220763. eCollection 2019.


Glucose dysregulation in pre-clinical Alzheimer's disease.

Connolly NMC, Theurey P, Pizzo P.

Aging (Albany NY). 2019 Aug 4;11(15):5296-5297. doi: 10.18632/aging.102146. Epub 2019 Aug 4. No abstract available.


Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression.

Costard LS, Neubert V, Venø MT, Su J, Kjems J, Connolly NMC, Prehn JHM, Schratt G, Henshall DC, Rosenow F, Bauer S.

Brain Stimul. 2019 Nov - Dec;12(6):1390-1401. doi: 10.1016/j.brs.2019.06.009. Epub 2019 Jun 7.


Factors Associated with the Initiation of Long-Acting Injectable Paliperidone Palmitate Versus Aripiprazole Among Medicaid Patients with Schizophrenia: An Observational Study.

Cai Q, Patel C, Kim E, Connolly N, Tunceli O, El Khoury AC.

Adv Ther. 2019 Apr;36(4):858-869. doi: 10.1007/s12325-019-00913-w. Epub 2019 Mar 8.


Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons.

Theurey P, Connolly NMC, Fortunati I, Basso E, Lauwen S, Ferrante C, Moreira Pinho C, Joselin A, Gioran A, Bano D, Park DS, Ankarcrona M, Pizzo P, Prehn JHM.

Aging Cell. 2019 Jun;18(3):e12924. doi: 10.1111/acel.12924. Epub 2019 Feb 21.


Ambient ozone and fine particulate matter exposures and autism spectrum disorder in metropolitan Cincinnati, Ohio.

Kaufman JA, Wright JM, Rice G, Connolly N, Bowers K, Anixt J.

Environ Res. 2019 Apr;171:218-227. doi: 10.1016/j.envres.2019.01.013. Epub 2019 Jan 10.


Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy.

Raoof R, Bauer S, El Naggar H, Connolly NMC, Brennan GP, Brindley E, Hill T, McArdle H, Spain E, Forster RJ, Prehn JHM, Hamer H, Delanty N, Rosenow F, Mooney C, Henshall DC.

EBioMedicine. 2018 Dec;38:127-141. doi: 10.1016/j.ebiom.2018.10.068. Epub 2018 Nov 2.


Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma.

Connolly NP, Shetty AC, Stokum JA, Hoeschele I, Siegel MB, Miller CR, Kim AJ, Ho CY, Davila E, Simard JM, Devine SE, Rossmeisl JH, Holland EC, Winkles JA, Woodworth GF.

Sci Rep. 2018 Jan 19;8(1):1180. doi: 10.1038/s41598-018-19451-6.


Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM.

Cell Death Differ. 2018 Mar;25(3):542-572. doi: 10.1038/s41418-017-0020-4. Epub 2017 Dec 11. Review.


Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform.

Anilkumar U, Weisova P, Schmid J, Bernas T, Huber HJ, Düssmann H, Connolly NMC, Prehn JHM.

PLoS One. 2017 Nov 16;12(11):e0188343. doi: 10.1371/journal.pone.0188343. eCollection 2017.


Decreased non-specific adhesivity, receptor targeted (DART) nanoparticles exhibit improved dispersion, cellular uptake, and tumor retention in invasive gliomas.

Wadajkar AS, Dancy JG, Roberts NB, Connolly NP, Strickland DK, Winkles JA, Woodworth GF, Kim AJ.

J Control Release. 2017 Dec 10;267:144-153. doi: 10.1016/j.jconrel.2017.09.006. Epub 2017 Sep 5.


Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus.

Raoof R, Jimenez-Mateos EM, Bauer S, Tackenberg B, Rosenow F, Lang J, Onugoren MD, Hamer H, Huchtemann T, Körtvélyessy P, Connolly NMC, Pfeiffer S, Prehn JHM, Farrell MA, O'Brien DF, Henshall DC, Mooney C.

Sci Rep. 2017 Jun 12;7(1):3328. doi: 10.1038/s41598-017-02969-6.


Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancer.

Connolly NP, Stokum JA, Schneider CS, Ozawa T, Xu S, Galisteo R, Castellani RJ, Kim AJ, Simard JM, Winkles JA, Holland EC, Woodworth GF.

PLoS One. 2017 Mar 30;12(3):e0174557. doi: 10.1371/journal.pone.0174557. eCollection 2017.


Thoracic epidural catheter for postoperative pain control following an ineffective transversus abdominis plane block using liposome bupivacaine.

Terrien BD, Espinoza D, Stehman CC, Rodriguez GA, Connolly NC.

J Pain Res. 2017 Jan 16;10:191-196. doi: 10.2147/JPR.S111589. eCollection 2017.


miRNAmeConverter: an R/bioconductor package for translating mature miRNA names to different miRBase versions.

Haunsberger SJ, Connolly NM, Prehn JH.

Bioinformatics. 2017 Feb 15;33(4):592-593. doi: 10.1093/bioinformatics/btw660.


Retrospective analysis of quality improvement when using liposome bupivacaine for postoperative pain control.

King NM, Quiko AS, Slotto JG, Connolly NC, Hackworth RJ, Heil JW.

J Pain Res. 2016 Apr 21;9:233-40. doi: 10.2147/JPR.S102305. eCollection 2016.


Use of Shotgun Metagenome Sequencing To Detect Fecal Colonization with Multidrug-Resistant Bacteria in Children.

Andersen H, Connolly N, Bangar H, Staat M, Mortensen J, Deburger B, Haslam DB.

J Clin Microbiol. 2016 Jul;54(7):1804-1813. doi: 10.1128/JCM.02638-15. Epub 2016 Apr 27.


Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions.

Connolly NM, D'Orsi B, Monsefi N, Huber HJ, Prehn JH.

PLoS One. 2016 Feb 3;11(2):e0148326. doi: 10.1371/journal.pone.0148326. eCollection 2016.


Maternal metabolic risk factors for autism spectrum disorder-An analysis of electronic medical records and linked birth data.

Connolly N, Anixt J, Manning P, Ping-I Lin D, Marsolo KA, Bowers K.

Autism Res. 2016 Aug;9(8):829-37. doi: 10.1002/aur.1586. Epub 2016 Jan 29.


Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier.

Hersh DS, Wadajkar AS, Roberts N, Perez JG, Connolly NP, Frenkel V, Winkles JA, Woodworth GF, Kim AJ.

Curr Pharm Des. 2016;22(9):1177-1193. Review.


Nanostructuring of Palladium with Low-Temperature Helium Plasma.

Fiflis P, Christenson MP, Connolly N, Ruzic DN.

Nanomaterials (Basel). 2015 Nov 25;5(4):2007-2018. doi: 10.3390/nano5042007.


The TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeutics.

Perez JG, Tran NL, Rosenblum MG, Schneider CS, Connolly NP, Kim AJ, Woodworth GF, Winkles JA.

Oncogene. 2016 Apr 28;35(17):2145-55. doi: 10.1038/onc.2015.310. Epub 2015 Aug 24. Review.


A test of stress, cues, and re-exposure to large wins as potential reinstaters of suboptimal decision making in rats.

Connolly NP, Kim JS, Tunstall BJ, Kearns DN.

Front Psychol. 2015 Apr 7;6:394. doi: 10.3389/fpsyg.2015.00394. eCollection 2015.


D4 dopamine receptor-specific antagonist improves reversal learning impairment in amphetamine-treated male rats.

Connolly NP, Gomez-Serrano M.

Exp Clin Psychopharmacol. 2014 Dec;22(6):557-64. doi: 10.1037/a0038216. Epub 2014 Oct 20.


The metabolic response to excitotoxicity - lessons from single-cell imaging.

Connolly NM, Prehn JH.

J Bioenerg Biomembr. 2015 Apr;47(1-2):75-88. doi: 10.1007/s10863-014-9578-4. Epub 2014 Sep 28. Review.


Single-cell imaging of bioenergetic responses to neuronal excitotoxicity and oxygen and glucose deprivation.

Connolly NM, Düssmann H, Anilkumar U, Huber HJ, Prehn JH.

J Neurosci. 2014 Jul 30;34(31):10192-205. doi: 10.1523/JNEUROSCI.3127-13.2014.


Integrating public data sets for analysis of maternal airborne environmental exposures and stillbirth.

Hall ES, Connolly N, Jones DE, DeFranco EA.

AMIA Annu Symp Proc. 2014 Nov 14;2014:599-605. eCollection 2014.


Does relational dysfunction mediate the association between anxiety disorders and later depression? Testing an interpersonal model of comorbidity.

Starr LR, Hammen C, Connolly NP, Brennan PA.

Depress Anxiety. 2014 Jan;31(1):77-86. doi: 10.1002/da.22172. Epub 2013 Aug 26.


Anterior mediastinal mass biopsy and resection: anesthetic techniques and perioperative concerns.

Rath L, Gullahorn G, Connolly N, Pratt T, Boswell G, Cornelissen C.

Semin Cardiothorac Vasc Anesth. 2012 Dec;16(4):235-42. doi: 10.1177/1089253212454336. Epub 2012 Aug 13.


Chronic ramelteon treatment in a mouse model of Alzheimer's disease.

McKenna JT, Christie MA, Jeffrey BA, McCoy JG, Lee E, Connolly NP, Ward CP, Strecker RE.

Arch Ital Biol. 2012 Mar;150(1):5-14. doi: 10.4449/aib.v149i5.1375.


Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate.

Davila D, Connolly NM, Bonner H, Weisová P, Dussmann H, Concannon CG, Huber HJ, Prehn JH.

Cell Death Differ. 2012 Oct;19(10):1677-88. doi: 10.1038/cdd.2012.49. Epub 2012 Apr 27.


Patents and growth.

Pentland AP, Connolly NL, Fahner-Vihtelic JE.

J Invest Dermatol. 2012 Mar;132(3 Pt 2):1037-41. doi: 10.1038/jid.2011.429.


A structured approach to the study of metabolic control principles in intact and impaired mitochondria.

Huber HJ, Connolly NM, Dussmann H, Prehn JH.

Mol Biosyst. 2012 Mar;8(3):828-42. doi: 10.1039/c2mb05434e. Epub 2012 Jan 5.


Specificity of Stress Generation: A Comparison of Adolescents with Depressive, Anxiety, and Comorbid Diagnoses.

Connolly NP, Eberhart NK, Hammen CL, Brennan PA.

Int J Cogn Ther. 2010 Dec 1;3(4):368-379.


One week of exposure to intermittent hypoxia impairs attentional set-shifting in rats.

McCoy JG, McKenna JT, Connolly NP, Poeta DL, Ling L, McCarley RW, Strecker RE.

Behav Brain Res. 2010 Jun 26;210(1):123-6. doi: 10.1016/j.bbr.2010.01.043. Epub 2010 Feb 1.


Spatial learning and memory deficits following exposure to 24 h of sleep fragmentation or intermittent hypoxia in a rat model of obstructive sleep apnea.

Ward CP, McCoy JG, McKenna JT, Connolly NP, McCarley RW, Strecker RE.

Brain Res. 2009 Oct 19;1294:128-37. doi: 10.1016/j.brainres.2009.07.064. Epub 2009 Jul 28.


A comparison of inferface pressures of three compression bandage systems.

Hanna R, Bohbot S, Connolly N.

Br J Nurs. 2008 Nov 13-26;17(20):S16-24.


Production of a dendritic cell-based vaccine containing inactivated autologous virus for therapy of patients with chronic human immunodeficiency virus type 1 infection.

Whiteside TL, Piazza P, Reiter A, Stanson J, Connolly NC, Rinaldo CR Jr, Riddler SA.

Clin Vaccine Immunol. 2009 Feb;16(2):233-40. doi: 10.1128/CVI.00066-08. Epub 2008 Nov 26.


24 hours of sleep deprivation in the rat increases sleepiness and decreases vigilance: introduction of the rat-psychomotor vigilance task.

Christie MA, McKenna JT, Connolly NP, McCarley RW, Strecker RE.

J Sleep Res. 2008 Dec;17(4):376-84. doi: 10.1111/j.1365-2869.2008.00698.x. Epub 2008 Oct 6. Erratum in: J Sleep Res. 2009 Mar;18(1):143.


Therapeutic immunization with human immunodeficiency virus type 1 (HIV-1) peptide-loaded dendritic cells is safe and induces immunogenicity in HIV-1-infected individuals.

Connolly NC, Whiteside TL, Wilson C, Kondragunta V, Rinaldo CR, Riddler SA.

Clin Vaccine Immunol. 2008 Feb;15(2):284-92. Epub 2007 Oct 17.


Treating HIV-1 infection with dendritic cells.

Connolly NC, Colleton BA, Rinaldo CR.

Curr Opin Mol Ther. 2007 Aug;9(4):353-63. Review. Erratum in: Curr Opin Mol Ther. 2007 Oct;9(5):515.


Levels of antigen processing machinery components in dendritic cells generated for vaccination of HIV-1+ subjects.

Connolly N, Riddler S, Stanson J, Gooding W, Rinaldo CR, Ferrone S, Whiteside TL.

AIDS. 2007 Aug 20;21(13):1683-92.


A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma.

Shaw DM, Connolly NB, Patel PM, Kilany S, Hedlund G, Nordle O, Forsberg G, Zweit J, Stern PL, Hawkins RE.

Br J Cancer. 2007 Feb 26;96(4):567-74. Epub 2007 Feb 6.


Stress sensitization and adolescent depressive severity as a function of childhood adversity: a link to anxiety disorders.

Espejo EP, Hammen CL, Connolly NP, Brennan PA, Najman JM, Bor W.

J Abnorm Child Psychol. 2007 Apr;35(2):287-99. Epub 2006 Dec 30.


CD27 and CD57 expression reveals atypical differentiation of human immunodeficiency virus type 1-specific memory CD8+ T cells.

Hoji A, Connolly NC, Buchanan WG, Rinaldo CR Jr.

Clin Vaccine Immunol. 2007 Jan;14(1):74-80. Epub 2006 Nov 1.


Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial.

Harrop R, Connolly N, Redchenko I, Valle J, Saunders M, Ryan MG, Myers KA, Drury N, Kingsman SM, Hawkins RE, Carroll MW.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3416-24.

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