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A marine viral halogenase that iodinates diverse substrates.

Gkotsi DS, Ludewig H, Sharma SV, Connolly JA, Dhaliwal J, Wang Y, Unsworth WP, Taylor RJK, McLachlan MMW, Shanahan S, Naismith JH, Goss RJM.

Nat Chem. 2019 Oct 14. doi: 10.1038/s41557-019-0349-z. [Epub ahead of print]


Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization.

Robinson JR, Carroll RJ, Bastarache L, Chen Q, Mou Z, Wei WQ, Connolly JJ, Mentch F, Sleiman P, Crane PK, Hebbring SJ, Stanaway IB, Crosslin DR, Gordon AS, Rosenthal EA, Carrell D, Hayes MG, Wei W, Petukhova L, Namjou B, Zhang G, Safarova MS, Walton NA, Still C, Bottinger EP, Loos RJF, Murphy SN, Jackson GP, Kullo IJ, Hakonarson H, Jarvik GP, Larson EB, Weng C, Roden DM, Denny JC.

World J Surg. 2019 Oct 11. doi: 10.1007/s00268-019-05202-9. [Epub ahead of print]


A Metacognitive Intervention of Narrative Imagery for young people with cystic fibrosis: A feasibility study.

Russell JK, Strodl E, Connolly J, Kavanagh DJ.

J Health Psychol. 2019 Sep 18:1359105319876336. doi: 10.1177/1359105319876336. [Epub ahead of print]


Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor.

Connolly JPR, O'Boyle N, Turner NCA, Browning DF, Roe AJ.

Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19695-19704. doi: 10.1073/pnas.1903461116. Epub 2019 Sep 9.


CNV Association of Diverse Clinical Phenotypes from eMERGE reveals novel disease biology underlying cardiovascular disease.

Glessner JT, Li J, Desai A, Palmer M, Kim D, Lucas AM, Chang X, Connolly JJ, Almoguera B, Harley JB, Jarvik GP, Ritchie MD, Sleiman PMA, Roden DM, Crosslin D, Hakonarson H.

Int J Cardiol. 2019 Jul 19. pii: S0167-5273(19)30191-3. doi: 10.1016/j.ijcard.2019.07.058. [Epub ahead of print]


Reliability and validity of PROMIS® pediatric family relationships short form in children 8-17 years of age with chronic disease.

Cox ED, Connolly JR, Palta M, Rajamanickam VP, Flynn KE.

Qual Life Res. 2019 Aug 10. doi: 10.1007/s11136-019-02266-x. [Epub ahead of print]


TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner.

Celhar T, Lu HK, Benso L, Rakhilina L, Lee HY, Tripathi S, Zharkova O, Ong WY, Yasuga H, Au B, Marlier D, Lim LHK, Thamboo TP, Mudgett JS, Mackey MF, Zaller DM, Connolly JE, Fairhurst AM.

Front Immunol. 2019 Jul 10;10:1546. doi: 10.3389/fimmu.2019.01546. eCollection 2019.


Simplifying the Proteome: Analytical Strategies for Improving Peak Capacity.

Gethings LA, Connolly JB.

Adv Exp Med Biol. 2019;1140:501-513. doi: 10.1007/978-3-030-15950-4_29.


Physician Knowledge of Breast Cancer Recurrence and Contralateral Breast Cancer Risk is Associated with Increased Recommendations for Contralateral Prophylactic Mastectomy: a Survey of Physicians at NAPBC-Accredited Centers.

Kantor O, Chang C, Bleicher RJ, Moran M, Connolly JL, Kurtzman SH, Yao K; National Accreditation Program for Breast Centers Data Working Group.

Ann Surg Oncol. 2019 Oct;26(10):3080-3088. doi: 10.1245/s10434-019-07559-6. Epub 2019 Jul 24.


Non-Vitamin K Antagonist Oral Anticoagulants and Angioedema: A Cohort and Case-Crossover Study.

Connolly JG, Schneeweiss S, Glynn RJ, Gagne JJ.

Drug Saf. 2019 Jul 18. doi: 10.1007/s40264-019-00852-z. [Epub ahead of print]


Development of a point of care system for automated coma prognosis: a prospective cohort study protocol.

Connolly JF, Reilly JP, Fox-Robichaud A, Britz P, Blain-Moraes S, Sonnadara R, Hamielec C, Herrera-Díaz A, Boshra R.

BMJ Open. 2019 Jul 17;9(7):e029621. doi: 10.1136/bmjopen-2019-029621.


GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.

Namjou B, Lingren T, Huang Y, Parameswaran S, Cobb BL, Stanaway IB, Connolly JJ, Mentch FD, Benoit B, Niu X, Wei WQ, Carroll RJ, Pacheco JA, Harley ITW, Divanovic S, Carrell DS, Larson EB, Carey DJ, Verma S, Ritchie MD, Gharavi AG, Murphy S, Williams MS, Crosslin DR, Jarvik GP, Kullo IJ, Hakonarson H, Li R; eMERGE Network, Xanthakos SA, Harley JB.

BMC Med. 2019 Jul 17;17(1):135. doi: 10.1186/s12916-019-1364-z.


From Group-Level Statistics to Single-Subject Prediction: Machine Learning Detection of Concussion in Retired Athletes.

Boshra R, Dhindsa K, Boursalie O, Ruiter KI, Sonnadara R, Samavi R, Doyle TE, Reilly JP, Connolly JF.

IEEE Trans Neural Syst Rehabil Eng. 2019 Jul;27(7):1492-1501. doi: 10.1109/TNSRE.2019.2922553. Epub 2019 Jun 12.


Electrophysiological evidence for the integral nature of tone in Mandarin spoken word recognition.

Ho A, Boshra R, Schmidtke D, Oralova G, Moro AL, Service E, Connolly JF.

Neuropsychologia. 2019 Aug;131:325-332. doi: 10.1016/j.neuropsychologia.2019.05.031. Epub 2019 Jun 8.


The platypus: evolutionary history, biology, and an uncertain future.

Bino G, Kingsford RT, Archer M, Connolly JH, Day J, Dias K, Goldney D, Gongora J, Grant T, Griffiths J, Hawke T, Klamt M, Lunney D, Mijangos L, Munks S, Sherwin W, Serena M, Temple-Smith P, Thomas J, Williams G, Whittington C.

J Mammal. 2019 Apr 24;100(2):308-327. doi: 10.1093/jmammal/gyz058.


Impact of connective tissue graft thickness on surgical outcomes: A pilot randomized clinical trial.

Moisa DH, Connolly JA, Cheng B, Lalla E.

J Periodontol. 2019 Sep;90(9):966-972. doi: 10.1002/JPER.18-0741. Epub 2019 May 8.


Enhancing oxygen delivery to ovarian follicles by three different methods markedly improves growth in serum-containing culture medium.

Connolly JM, Kane MT, Quinlan LR, Hynes AC.

Reprod Fertil Dev. 2019 Apr 12. doi: 10.1071/RD18286. [Epub ahead of print]


Genomic and transcriptomic characterization of Pseudomonas aeruginosa small colony variants derived from a chronic infection model.

Irvine S, Bunk B, Bayes HK, Spröer C, Connolly JPR, Six A, Evans TJ, Roe AJ, Overmann J, Walker D.

Microb Genom. 2019 Apr;5(4). doi: 10.1099/mgen.0.000262. Epub 2019 Mar 28.


Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel.

Chiang T, Liu X, Wu TJ, Hu J, Sedlazeck FJ, White S, Schaid D, Andrade M, Jarvik GP, Crosslin D, Stanaway I, Carrell DS, Connolly JJ, Hakonarson H, Groopman EE, Gharavi AG, Fedotov A, Bi W, Leduc MS, Murdock DR, Jiang Y, Meng L, Eng CM, Wen S, Yang Y, Muzny DM, Boerwinkle E, Salerno W, Venner E, Gibbs RA.

Genet Med. 2019 Sep;21(9):2135-2144. doi: 10.1038/s41436-019-0475-4. Epub 2019 Mar 20.


On the Relative Contribution of Deep Convolutional Neural Networks for SSVEP-Based Bio-Signal Decoding in BCI Speller Applications.

Podmore JJ, Breckon TP, Aznan NKN, Connolly JD.

IEEE Trans Neural Syst Rehabil Eng. 2019 Apr;27(4):611-618. doi: 10.1109/TNSRE.2019.2904791. Epub 2019 Mar 13.


Comparative effectiveness of generic and brand-name medication use: A database study of US health insurance claims.

Desai RJ, Sarpatwari A, Dejene S, Khan NF, Lii J, Rogers JR, Dutcher SK, Raofi S, Bohn J, Connolly JG, Fischer MA, Kesselheim AS, Gagne JJ.

PLoS Med. 2019 Mar 13;16(3):e1002763. doi: 10.1371/journal.pmed.1002763. eCollection 2019 Mar.


Determining the health benefits of green space: Does gentrification matter?

Cole HVS, Triguero-Mas M, Connolly JJT, Anguelovski I.

Health Place. 2019 May;57:1-11. doi: 10.1016/j.healthplace.2019.02.001. Epub 2019 Mar 4.


Enhancing Antigen Cross-Presentation in Human Monocyte-Derived Dendritic Cells by Recruiting the Intracellular Fc Receptor TRIM21.

Ng PML, Kaliaperumal N, Lee CY, Chin WJ, Tan HC, Au VB, Goh AX, Tan QW, Yeo DSG, Connolly JE, Wang CI.

J Immunol. 2019 Apr 15;202(8):2307-2319. doi: 10.4049/jimmunol.1800462. Epub 2019 Feb 22.


Quantifying bias reduction with fixed-duration versus all-available covariate assessment periods.

Connolly JG, Schneeweiss S, Glynn RJ, Gagne JJ.

Pharmacoepidemiol Drug Saf. 2019 May;28(5):665-670. doi: 10.1002/pds.4729. Epub 2019 Feb 20.


The Asian cyclopoid copepod Mesocyclops pehpeiensis reported from the western basin of Lake Erie.

Connolly J, Watkins JM, Hinchey EK, Rudstam LG, Reid JW.

J Great Lakes Res. 2019;45(1):196-201. doi: 10.1016/j.jglr.2018.11.005.


Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586.

Connolly JA, Wilson A, Macioszek M, Song Z, Wang L, Mohammad HH, Yadav M, di Martino M, Miller CE, Hothersall J, Haines AS, Stephens ER, Crump MP, Willis CL, Simpson TJ, Winn PJ, Thomas CM.

Sci Rep. 2019 Feb 7;9(1):1542. doi: 10.1038/s41598-018-38038-9.


Impact of Breast Center Accreditation on Compliance with Breast Quality Performance Measures at Commission on Cancer-Accredited Centers.

Miller ME, Bleicher RJ, Kaufman CS, Kurtzman SH, Chang C, Wang CH, Pollitt KA, Connolly J, Winchester DP, Yao KA.

Ann Surg Oncol. 2019 May;26(5):1202-1211. doi: 10.1245/s10434-018-07108-7. Epub 2019 Jan 25.


Cytokine Profiling in Patients With Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy.

Agrawal R, Balne PK, Wei X, Bijin VA, Lee B, Ghosh A, Narayanan R, Agrawal M, Connolly J.

Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):376-382. doi: 10.1167/iovs.18-24387.


Clinical Manifestations and Long-term Outcomes of IgG4-Related Kidney and Retroperitoneal Involvement in a United Kingdom IgG4-Related Disease Cohort.

Evans RDR, Cargill T, Goodchild G, Oliveira B, Rodriguez-Justo M, Pepper R, Connolly J, Salama A, Webster G, Barnes E, Culver EL.

Kidney Int Rep. 2018 Sep 1;4(1):48-58. doi: 10.1016/j.ekir.2018.08.011. eCollection 2019 Jan.


Enrichment sampling for a multi-site patient survey using electronic health records and census data.

Mercaldo ND, Brothers KB, Carrell DS, Clayton EW, Connolly JJ, Holm IA, Horowitz CR, Jarvik GP, Kitchner TE, Li R, McCarty CA, McCormick JB, McManus VD, Myers MF, Pankratz JJ, Shrubsole MJ, Smith ME, Stallings SC, Williams JL, Schildcrout JS.

J Am Med Inform Assoc. 2019 Mar 1;26(3):219-227. doi: 10.1093/jamia/ocy164.


Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine.

Skibinski DAG, Jones LA, Zhu YO, Xue LW, Au B, Lee B, Naim ANM, Lee A, Kaliaperumal N, Low JGH, Lee LS, Poidinger M, Saudan P, Bachmann M, Ooi EE, Hanson BJ, Novotny-Diermayr V, Matter A, Fairhurst AM, Hibberd ML, Connolly JE.

Sci Rep. 2018 Dec 20;8(1):18007. doi: 10.1038/s41598-018-36703-7.


Prescribing lessons from an ocular chemical injury: Vitaros inadvertently dispensed instead of VitA-POS.

Edington M, Connolly J, Lockington D.

BMJ Case Rep. 2018 Dec 3;11(1). pii: bcr-2018-227468. doi: 10.1136/bcr-2018-227468.


Effect of Playing and Training at Altitude on Concussion Incidence in Professional Football.

Connolly JG, Nathanson JT, Sobotka S, Haider S, Gometz A, Lovell M, Choudhri T.

Orthop J Sports Med. 2018 Dec 7;6(12):2325967118794928. doi: 10.1177/2325967118794928. eCollection 2018 Dec.


Control freaks-signals and cues governing the regulation of virulence in attaching and effacing pathogens.

Turner NCA, Connolly JPR, Roe AJ.

Biochem Soc Trans. 2019 Feb 28;47(1):229-238. doi: 10.1042/BST20180546. Epub 2018 Dec 17. Review.


A Flow Cytometry-Based Assay for High-Throughput Detection and Quantification of Neutrophil Extracellular Traps in Mixed Cell Populations.

Zharkova O, Tay SH, Lee HY, Shubhita T, Ong WY, Lateef A, MacAry PA, Lim LHK, Connolly JE, Fairhurst AM.

Cytometry A. 2019 Mar;95(3):268-278. doi: 10.1002/cyto.a.23672. Epub 2018 Dec 14.


The Future of Complementarity: Disentangling Causes from Consequences.

Barry KE, Mommer L, van Ruijven J, Wirth C, Wright AJ, Bai Y, Connolly J, De Deyn GB, de Kroon H, Isbell F, Milcu A, Roscher C, Scherer-Lorenzen M, Schmid B, Weigelt A.

Trends Ecol Evol. 2019 Feb;34(2):167-180. doi: 10.1016/j.tree.2018.10.013. Epub 2018 Dec 4. Review.


It can be beautiful or destructive: Street-involved youth's perceptions of their romantic relationships and resilience.

Joly LE, Connolly J.

J Adolesc. 2019 Jan;70:43-52. doi: 10.1016/j.adolescence.2018.11.006. Epub 2018 Dec 4.


Disruption of function: Neurophysiological markers of cognitive deficits in retired football players.

Ruiter KI, Boshra R, Doughty M, Noseworthy M, Connolly JF.

Clin Neurophysiol. 2019 Jan;130(1):111-121. doi: 10.1016/j.clinph.2018.10.013. Epub 2018 Nov 26.


Predicting posttraumatic stress and depression symptoms among adolescents in the extended postpartum period.

Anderson CA, Connolly JP.

Heliyon. 2018 Nov 27;4(11):e00965. doi: 10.1016/j.heliyon.2018.e00965. eCollection 2018 Nov.


Author Correction: Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion.

Connolly JPR, Slater SL, O'Boyle N, Goldstone RJ, Crepin VF, Ruano-Gallego D, Herzyk P, Smith DGE, Douce GR, Frankel G, Roe AJ.

Nat Commun. 2018 Nov 29;9(1):5148. doi: 10.1038/s41467-018-07612-0.


Is it feasible to deliver a complex intervention to improve the outcome of falls in people with dementia? A protocol for the DIFRID feasibility study.

Allan LM, Wheatley A, Flynn E, Smith A, Fox C, Howel D, Barber R, Homer TM, Robinson L, Parry SW, Corner L, Connolly JA, Rochester L, Bamford C.

Pilot Feasibility Stud. 2018 Nov 10;4:170. doi: 10.1186/s40814-018-0364-7. eCollection 2018.


Characterization of the Mode of Action of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis.

McHugh RE, O'Boyle N, Connolly JPR, Hoskisson PA, Roe AJ.

Infect Immun. 2019 Jan 24;87(2). pii: e00595-18. doi: 10.1128/IAI.00595-18. Print 2019 Feb.


Non-invasive Seizure Localization with Ictal Single-Photon Emission Computed Tomography is Impacted by Preictal/Early Ictal Network Dynamics.

Stamoulis C, Connolly J, Axeen E, Kaulas H, Bolton J, Dorfman K, Halford JJ, Duffy FH, Treves ST, Pearl PL.

IEEE Trans Biomed Eng. 2018 Nov 9. doi: 10.1109/TBME.2018.2880575. [Epub ahead of print]


Brachionus leydigii (Monogononta: Ploima) reported from the western basin of Lake Erie.

Connolly JK, Watkins JM, Marshall CC, Adams JM, Rudstam LG, Błędzki LA.

J Great Lakes Res. 2018 Oct;44(5):1123-1126. doi: 10.1016/j.jglr.2018.07.010.


Novel locus for atopic dermatitis in African Americans and replication in European Americans.

Almoguera B, Vazquez L, Mentch F, March ME, Connolly JJ, Peissig PL, Linneman JG, Plaza-Serón MDC, Pino-Yanes M, Burchard EG, Brilliant M, Sleiman P, Hakonarson H.

J Allergy Clin Immunol. 2019 Mar;143(3):1229-1231. doi: 10.1016/j.jaci.2018.10.038. Epub 2018 Nov 9. No abstract available.


A Machine Learning Framework for Automatic and Continuous MMN Detection With Preliminary Results for Coma Outcome Prediction.

Armanfard N, Komeili M, Reilly JP, Connolly JF.

IEEE J Biomed Health Inform. 2019 Jul;23(4):1794-1804. doi: 10.1109/JBHI.2018.2877738. Epub 2018 Oct 24.


Do corneas melt in the Scottish summer? A 10-year review of corneal perforations requiring cyanoacrylate gluing in theatre at a tertiary referral centre.

Edington M, Connolly J, Lockington D.

Eye (Lond). 2019 Feb;33(2):339-340. doi: 10.1038/s41433-018-0247-4. Epub 2018 Oct 24. No abstract available.


Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis.

Scott NA, Andrusaite A, Andersen P, Lawson M, Alcon-Giner C, Leclaire C, Caim S, Le Gall G, Shaw T, Connolly JPR, Roe AJ, Wessel H, Bravo-Blas A, Thomson CA, Kästele V, Wang P, Peterson DA, Bancroft A, Li X, Grencis R, Mowat AM, Hall LJ, Travis MA, Milling SWF, Mann ER.

Sci Transl Med. 2018 Oct 24;10(464). pii: eaao4755. doi: 10.1126/scitranslmed.aao4755.


Leveraging electronic health records to assess the role of ADRB2 single nucleotide polymorphisms in predicting exacerbation frequency in asthma patients.

Sood N, Connolly JJ, Mentch FD, Vazquez L, Sleiman PMA, Hysinger EB, Hakonarson H; eMERGE Outcomes Workgroup.

Pharmacogenet Genomics. 2018 Nov;28(11):256-259. doi: 10.1097/FPC.0000000000000355.


Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion.

Connolly JPR, Slater SL, O'Boyle N, Goldstone RJ, Crepin VF, Ruano-Gallego D, Herzyk P, Smith DGE, Douce GR, Frankel G, Roe AJ.

Nat Commun. 2018 Oct 10;9(1):4187. doi: 10.1038/s41467-018-06701-4. Erratum in: Nat Commun. 2018 Nov 29;9(1):5148.

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