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Parametrial fat tissue from high fat diet-treated SKH-1 mice stimulates transformation of mouse epidermal JB6 cells.

Bernard JJ, Lou YR, Peng QY, Li T, Vakil PR, Ding N, Laskin JD, Dong Z, Conney AH, Lu YP.

J Carcinog Mutagen. 2014 Jul 31;5(183):2157-2518.


α-Tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells.

Huang H, Chen S, Van Doren J, Li D, Farichon C, He Y, Zhang Q, Zhang K, Conney AH, Goodin S, Du Z, Zheng X.

Mol Med Rep. 2015 Jun;11(6):4573-8. doi: 10.3892/mmr.2015.3238. Epub 2015 Jan 22.


Anticancer activity of Acanthopanax trifoliatus (L) Merr extracts is associated with inhibition of NF-kB activity and decreased Erk1/2 and Akt phosphorylation.

Wang HQ, Li DL, Lu YJ, Cui XX, Zhou XF, Lin WP, Conney AH, Zhang K, Du ZY, Zheng X.

Asian Pac J Cancer Prev. 2014;15(21):9341-6.


Potent inhibitory effect of δ-tocopherol on prostate cancer cells cultured in vitro and grown as xenograft tumors in vivo.

Huang H, He Y, Cui XX, Goodin S, Wang H, Du ZY, Li D, Zhang K, Tony Kong AN, DiPaola RS, Yang CS, Conney AH, Zheng X.

J Agric Food Chem. 2014 Nov 5;62(44):10752-8. doi: 10.1021/jf504058f. Epub 2014 Oct 27.


Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages.

Saw CL, Yang AY, Huang MT, Liu Y, Lee JH, Khor TO, Su ZY, Shu L, Lu Y, Conney AH, Kong AN.

Cell Biosci. 2014 Aug 5;4:39. doi: 10.1186/2045-3701-4-39. eCollection 2014.


Curcumin analogues with high activity for inhibiting human prostate cancer cell growth and androgen receptor activation.

Zhou DY, Ding N, Du ZY, Cui XX, Wang H, Wei XC, Conney AH, Zhang K, Zheng X.

Mol Med Rep. 2014 Sep;10(3):1315-22. doi: 10.3892/mmr.2014.2380. Epub 2014 Jul 14.


Combination of Lipitor and Celebrex inhibits prostate cancer VCaP cells in vitro and in vivo.

Huang H, Cui XX, Chen S, Goodin S, Liu Y, He Y, Li D, Wang H, Van Doren J, Dipaola RS, Conney AH, Zheng X.

Anticancer Res. 2014 Jul;34(7):3357-63.


A triple combination of atorvastatin, celecoxib and tipifarnib strongly inhibits pancreatic cancer cells and xenograft pancreatic tumors.

Ding N, Cui XX, Gao Z, Huang H, Wei X, Du Z, Lin Y, Shih WJ, Rabson AB, Conney AH, Hu C, Zheng X.

Int J Oncol. 2014 Jun;44(6):2139-45. doi: 10.3892/ijo.2014.2350. Epub 2014 Mar 19.


Effects of curcumin analogues for inhibiting human prostate cancer cells and the growth of human PC-3 prostate xenografts in immunodeficient mice.

Zhou DY, Ding N, Van Doren J, Wei XC, Du ZY, Conney AH, Zhang K, Zheng X.

Biol Pharm Bull. 2014;37(6):1029-34. Epub 2014 Mar 19.


Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane.

Su ZY, Zhang C, Lee JH, Shu L, Wu TY, Khor TO, Conney AH, Lu YP, Kong AN.

Cancer Prev Res (Phila). 2014 Mar;7(3):319-29. doi: 10.1158/1940-6207.CAPR-13-0313-T. Epub 2014 Jan 17.


Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib.

Wang H, Cui XX, Goodin S, Ding N, Van Doren J, Du Z, Huang MT, Liu Y, Cheng X, Dipaola RS, Conney AH, Zheng X.

Oncol Rep. 2014 Feb;31(2):835-41. doi: 10.3892/or.2013.2885. Epub 2013 Nov 29.


Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice.

Bernard JJ, Lou YR, Peng QY, Li T, Conney AH, Lu YP.

Exp Mol Pathol. 2014 Feb;96(1):126-31. doi: 10.1016/j.yexmp.2013.10.011. Epub 2013 Oct 30.


Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice.

Lou Y, Peng Q, Li T, Nolan B, Bernard JJ, Wagner GC, Lin Y, Shih WJ, Conney AH, Lu Y.

Nutr Cancer. 2013;65(7):1002-13. doi: 10.1080/01635581.2013.812224. Epub 2013 Sep 26.


Synthesis and evaluation of curcumin-related compounds containing benzyl piperidone for their effects on human cancer cells.

Zhou DY, Zhang K, Conney AH, Ding N, Cui XX, Wang H, Verano M, Zhao SQ, Fan YX, Zheng X, Du ZY.

Chem Pharm Bull (Tokyo). 2013;61(11):1149-55. Epub 2013 Aug 27.


Anti-proliferative, anti-inflammatory and antioxidant effects of curcumin analogue A₂.

Du ZY, Wei X, Huang MT, Zheng X, Liu Y, Conney AH, Zhang K.

Arch Pharm Res. 2013 Oct;36(10):1204-10. doi: 10.1007/s12272-013-0216-1. Epub 2013 Jul 27.


Mechanisms of Caffeine-Induced Inhibition of UVB Carcinogenesis.

Conney AH, Lu YP, Lou YR, Kawasumi M, Nghiem P.

Front Oncol. 2013 Jun 17;3:144. doi: 10.3389/fonc.2013.00144. eCollection 2013.


Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene.

Chang RL, Wood AW, Huang MT, Xie JG, Cui XX, Reuhl KR, Boyd DR, Lin Y, Shih WJ, Balani SK, Yagi H, Jerina DM, Conney AH.

Carcinogenesis. 2013 Sep;34(9):2184-91. doi: 10.1093/carcin/bgt164. Epub 2013 May 13.


Effects of pyridine analogs of curcumin on growth, apoptosis and NF-κB activity in prostate cancer PC-3 cells.

Wei X, Zhou D, Wang H, Ding N, Cui XX, Wang H, Verano M, Zhang K, Conney AH, Zheng X, DU ZY.

Anticancer Res. 2013 Apr;33(4):1343-50.


Synthesis and biological evaluation of unsymmetrical curcumin analogues as tyrosinase inhibitors.

Jiang Y, Du Z, Xue G, Chen Q, Lu Y, Zheng X, Conney AH, Zhang K.

Molecules. 2013 Apr 3;18(4):3948-61. doi: 10.3390/molecules18043948.


Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation.

Su ZY, Khor TO, Shu L, Lee JH, Saw CL, Wu TY, Huang Y, Suh N, Yang CS, Conney AH, Wu Q, Kong AN.

Chem Res Toxicol. 2013 Mar 18;26(3):477-85. doi: 10.1021/tx300524p. Epub 2013 Mar 8.


Inhibition of progression of androgen-dependent prostate LNCaP tumors to androgen independence in SCID mice by oral caffeine and voluntary exercise.

Zheng X, Cui XX, Huang MT, Liu Y, Wagner GC, Lin Y, Shih WJ, Lee MJ, Yang CS, Conney AH.

Nutr Cancer. 2012;64(7):1029-37. doi: 10.1080/01635581.2012.716899.


Effects of 12-O-tetradecanoylphorbol-13-acetate in combination with gemcitabine on Panc-1 pancreatic cancer cells cultured in vitro or Panc-1 tumors grown in immunodeficient mice.

Zheng X, Cui XX, Gao Z, Verano M, Huang MT, Liu Y, Rabson AB, Conney AH.

Int J Oncol. 2012 Dec;41(6):2269-75. doi: 10.3892/ijo.2012.1651. Epub 2012 Oct 4.


Effects of cyclohexanone analogues of curcumin on growth, apoptosis and NF-κB activity in PC-3 human prostate cancer cells.

Wei X, DU ZY, Cui XX, Verano M, Mo RQ, Tang ZK, Conney AH, Zheng X, Zhang K.

Oncol Lett. 2012 Aug;4(2):279-284. Epub 2012 May 10.


Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat.

Conney AH, Lou YR, Nghiem P, Bernard JJ, Wagner GC, Lu YP.

Top Curr Chem. 2013;329:61-72. doi: 10.1007/128_2012_336.


Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet.

Lu YP, Lou YR, Bernard JJ, Peng QY, Li T, Lin Y, Shih WJ, Nghiem P, Shapses S, Wagner GC, Conney AH.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9065-70. doi: 10.1073/pnas.1205810109. Epub 2012 May 21.


Synthesis and evaluation of curcumin-related compounds for anticancer activity.

Wei X, Du ZY, Zheng X, Cui XX, Conney AH, Zhang K.

Eur J Med Chem. 2012 Jul;53:235-45. doi: 10.1016/j.ejmech.2012.04.005. Epub 2012 Apr 16.


Cigarette smoking, coffee drinking, and ingestion of charcoal-broiled beef as potential modifiers of drug therapy and confounders of clinical trials.

Conney AH, Reidenberg MM.

J Pharmacol Exp Ther. 2012 Jul;342(1):9-14. doi: 10.1124/jpet.112.193193. Epub 2012 Apr 18.


Folding-promoted TBAX-mediated selective demethylation of methoxybenzene-based macrocyclic aromatic pentamers.

Du Z, Qin B, Sun C, Liu Y, Zheng X, Zhang K, Conney AH, Zeng H.

Org Biomol Chem. 2012 Jun 7;10(21):4164-71. doi: 10.1039/c2ob25160d. Epub 2012 Mar 29.


Donald M. Jerina (1940–2011).

Conney AH.

Carcinogenesis. 2011 Sep;32(9):1403. No abstract available.


Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.

Kawasumi M, Lemos B, Bradner JE, Thibodeau R, Kim YS, Schmidt M, Higgins E, Koo SW, Angle-Zahn A, Chen A, Levine D, Nguyen L, Heffernan TP, Longo I, Mandinova A, Lu YP, Conney AH, Nghiem P.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13716-21. doi: 10.1073/pnas.1111378108. Epub 2011 Aug 15.


Inhibitory effect of dietary atorvastatin and celecoxib together with voluntary running wheel exercise on the progression of androgen-dependent LNCaP prostate tumors to androgen independence.

Zheng X, Cui XX, Gao Z, Zhao Y, Shi Y, Huang MT, Liu Y, Wagner GC, Lin Y, Shih WJ, Rao CV, Yang CS, Conney AH.

Exp Ther Med. 2011 Mar;2(2):221-228.


Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane.

Saw CL, Huang MT, Liu Y, Khor TO, Conney AH, Kong AN.

Mol Carcinog. 2011 Jun;50(6):479-86. doi: 10.1002/mc.20725. Epub 2010 Dec 28.


Effects of high-fat diets rich in either omega-3 or omega-6 fatty acids on UVB-induced skin carcinogenesis in SKH-1 mice.

Lou YR, Peng QY, Li T, Medvecky CM, Lin Y, Shih WJ, Conney AH, Shapses S, Wagner GC, Lu YP.

Carcinogenesis. 2011 Jul;32(7):1078-84. doi: 10.1093/carcin/bgr074. Epub 2011 Apr 27.


Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice.

Lu YP, Lou YR, Peng QY, Nghiem P, Conney AH.

Cancer Prev Res (Phila). 2011 Jul;4(7):1118-25. doi: 10.1158/1940-6207.CAPR-11-0116. Epub 2011 Apr 19.


Inhibitory Effect of a γ-Tocopherol-Rich Mixture of Tocopherols on the Formation and Growth of LNCaP Prostate Tumors in Immunodeficient Mice.

Zheng X, Cui XX, Khor TO, Huang Y, Dipaola RS, Goodin S, Lee MJ, Yang CS, Kong AN, Conney AH.

Cancers (Basel). 2011 Sep 28;3(4):3762-72. doi: 10.3390/cancers3043762.


A novel Gemini vitamin D analog represses the expression of a stem cell marker CD44 in breast cancer.

So JY, Lee HJ, Smolarek AK, Paul S, Wang CX, Maehr H, Uskokovic M, Zheng X, Conney AH, Cai L, Liu F, Suh N.

Mol Pharmacol. 2011 Mar;79(3):360-7. doi: 10.1124/mol.110.068403. Epub 2010 Nov 29.


Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independence.

Zheng X, Cui XX, Gao Z, Zhao Y, Lin Y, Shih WJ, Huang MT, Liu Y, Rabson A, Reddy B, Yang CS, Conney AH.

Cancer Prev Res (Phila). 2010 Jan;3(1):114-24. doi: 10.1158/1940-6207.CAPR-09-0059.


Bandaru s. Reddy: in memoriam (1930-2009).

Rao CV, Steele VE, Stoner GD, Conney AH.

Cancer Prev Res (Phila). 2009 Oct;2(10):912-3. doi: 10.1158/1940-6207.CAPR-09-0180. No abstract available.


ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine.

Heffernan TP, Kawasumi M, Blasina A, Anderes K, Conney AH, Nghiem P.

J Invest Dermatol. 2009 Jul;129(7):1805-15. doi: 10.1038/jid.2008.435. Epub 2009 Feb 26.


Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity.

Lee HJ, Paul S, Atalla N, Thomas PE, Lin X, Yang I, Buckley B, Lu G, Zheng X, Lou YR, Conney AH, Maehr H, Adorini L, Uskokovic M, Suh N.

Cancer Prev Res (Phila). 2008 Nov;1(6):476-84. doi: 10.1158/1940-6207.CAPR-08-0084.


Tumorigenic effect of some commonly used moisturizing creams when applied topically to UVB-pretreated high-risk mice.

Lu YP, Lou YR, Xie JG, Peng Q, Shih WJ, Lin Y, Conney AH.

J Invest Dermatol. 2009 Feb;129(2):468-75. doi: 10.1038/jid.2008.241. Epub 2008 Aug 14.


Inhibitory effect of voluntary running wheel exercise on the growth of human pancreatic Panc-1 and prostate PC-3 xenograft tumors in immunodeficient mice.

Zheng X, Cui XX, Huang MT, Liu Y, Shih WJ, Lin Y, Lu YP, Wagner GC, Conney AH.

Oncol Rep. 2008 Jun;19(6):1583-8.


Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.

Lu YP, Lou YR, Peng QY, Xie JG, Nghiem P, Conney AH.

Cancer Res. 2008 Apr 1;68(7):2523-9. doi: 10.1158/0008-5472.CAN-07-5955.


Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats.

Mesia-Vela S, Sanchez RI, Roberts KG, Reuhl KR, Conney AH, Kauffman FC.

Toxicology. 2008 Apr 3;246(1):63-72. doi: 10.1016/j.tox.2007.12.025. Epub 2008 Jan 6.


Inhibitory effects of caffeine analogues on neoplastic transformation: structure-activity relationship.

Rogozin EA, Lee KW, Kang NJ, Yu H, Nomura M, Miyamoto K, Conney AH, Bode AM, Dong Z.

Carcinogenesis. 2008 Jun;29(6):1228-34. doi: 10.1093/carcin/bgn016. Epub 2008 Jan 14.


Effect of caffeine on UVB-induced carcinogenesis, apoptosis, and the elimination of UVB-induced patches of p53 mutant epidermal cells in SKH-1 mice.

Conney AH, Kramata P, Lou YR, Lu YP.

Photochem Photobiol. 2008 Mar-Apr;84(2):330-8. doi: 10.1111/j.1751-1097.2007.00263.x. Epub 2008 Jan 7. Review.


Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin administration and high-fat diet on the body weight and hepatic estrogen metabolism in female C3H/HeN mice.

Zhu BT, Gallo MA, Burger CW Jr, Meeker RJ, Cai MX, Xu S, Conney AH.

Toxicol Appl Pharmacol. 2008 Jan 15;226(2):107-18. Epub 2007 Aug 31.


Atorvastatin and celecoxib inhibit prostate PC-3 tumors in immunodeficient mice.

Zheng X, Cui XX, Avila GE, Huang MT, Liu Y, Patel J, Kong AN, Paulino R, Shih WJ, Lin Y, Rabson AB, Reddy BS, Conney AH.

Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5480-7.

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