Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 28

1.

The potency-insolubility conundrum in pharmaceuticals: Mechanism and solution for hepatitis C protease inhibitors.

Connelly PR, Snyder PW, Zhang Y, McClain B, Quinn BP, Johnston S, Medek A, Tanoury J, Griffith J, Patrick Walters W, Dokou E, Knezic D, Bransford P.

Biophys Chem. 2015 Jan;196:100-8. doi: 10.1016/j.bpc.2014.08.008. Epub 2014 Sep 18.

2.

Getting physical to fix pharma.

Connelly PR, Vuong TM, Murcko MA.

Nat Chem. 2011 Aug 23;3(9):692-5. doi: 10.1038/nchem.1121.

PMID:
21860457
3.

Evaluation of measurement uncertainties in human diffusion tensor imaging (DTI)-derived parameters and optimization of clinical DTI protocols with a wild bootstrap analysis.

Zhu T, Liu X, Gaugh MD, Connelly PR, Ni H, Ekholm S, Schifitto G, Zhong J.

J Magn Reson Imaging. 2009 Feb;29(2):422-35. doi: 10.1002/jmri.21647.

PMID:
19161198
4.

An optimized wild bootstrap method for evaluation of measurement uncertainties of DTI-derived parameters in human brain.

Zhu T, Liu X, Connelly PR, Zhong J.

Neuroimage. 2008 Apr 15;40(3):1144-56. doi: 10.1016/j.neuroimage.2008.01.016. Epub 2008 Jan 26.

PMID:
18302985
5.

Thermodynamics of the helix-coil transition: Binding of S15 and a hybrid sequence, disulfide stabilized peptide to the S-protein.

Bastos M, Pease JH, Wemmer DE, Murphy KP, Connelly PR.

Proteins. 2001 Mar 1;42(4):523-30.

PMID:
11170206
6.

TTF-1 and HNF-3beta in the developing tracheoesophageal fistula: further evidence for the respiratory origin of the distal esophagus'.

Crisera CA, Connelly PR, Marmureanu AR, Li M, Rose MI, Longaker MT, Gittes GK.

J Pediatr Surg. 1999 Sep;34(9):1322-6.

PMID:
10507421
7.

Vascular development in the mouse embryonic pancreas and lung.

Colen KL, Crisera CA, Rose MI, Connelly PR, Longaker MT, Gittes GK.

J Pediatr Surg. 1999 May;34(5):781-5.

PMID:
10359181
8.

Epithelio-mesenchymal interactions in the developing mouse pancreas: morphogenesis of the adult architecture.

Rose MI, Crisera CA, Colen KL, Connelly PR, Longaker MT, Gittes GK.

J Pediatr Surg. 1999 May;34(5):774-9; discussion 780.

PMID:
10359180
9.

The ontogeny of TGF-beta1, -beta2, -beta3, and TGF-beta receptor-II expression in the pancreas: implications for regulation of growth and differentiation.

Crisera CA, Rose MI, Connelly PR, Li M, Colen KL, Longaker MT, Gittes GK.

J Pediatr Surg. 1999 May;34(5):689-93; discussion 693-4.

PMID:
10359165
10.

Esophageal atresia with tracheoesophageal fistula: suggested mechanism in faulty organogenesis.

Crisera CA, Connelly PR, Marmureanu AR, Colen KL, Rose MI, Li M, Longaker MT, Gittes GK.

J Pediatr Surg. 1999 Jan;34(1):204-8.

PMID:
10022173
11.

In vitro prefabrication of human cartilage shapes using fibrin glue and human chondrocytes.

Ting V, Sims CD, Brecht LE, McCarthy JG, Kasabian AK, Connelly PR, Elisseeff J, Gittes GK, Longaker MT.

Ann Plast Surg. 1998 Apr;40(4):413-20; discussion 420-1.

PMID:
9555998
13.

Supportive behaviors in natural support networks of people with serious mental illness.

Walsh J, Connelly PR.

Health Soc Work. 1996 Nov;21(4):296-303. No abstract available.

PMID:
8911961
14.

Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.

Fleming MA, Chambers SP, Connelly PR, Nimmesgern E, Fox T, Bruzzese FJ, Hoe ST, Fulghum JR, Livingston DJ, Stuver CM, Sintchak MD, Wilson KP, Thomson JA.

Biochemistry. 1996 Jun 4;35(22):6990-7.

PMID:
8679523
16.
17.

Enthalpy of hydrogen bond formation in a protein-ligand binding reaction.

Connelly PR, Aldape RA, Bruzzese FJ, Chambers SP, Fitzgibbon MJ, Fleming MA, Itoh S, Livingston DJ, Navia MA, Thomson JA, et al.

Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1964-8.

19.
20.

Heat capacity changes for protein-peptide interactions in the ribonuclease S system.

Varadarajan R, Connelly PR, Sturtevant JM, Richards FM.

Biochemistry. 1992 Feb 11;31(5):1421-6.

PMID:
1736999
21.

Thermodynamics of interaction of FK 506-binding protein and its ligands.

Connelly PR.

Transplant Proc. 1991 Dec;23(6):2883-5. No abstract available.

PMID:
1721304
22.

Thermodynamics of protein-peptide interactions in the ribonuclease S system studied by titration calorimetry.

Connelly PR, Varadarajan R, Sturtevant JM, Richards FM.

Biochemistry. 1990 Jun 26;29(25):6108-14.

PMID:
2383573
23.

Binding of oxygen and carbon monoxide to the hemocyanin from the spiny lobster.

Connelly PR, Johnson CR, Robert CH, Bak HJ, Gill SJ.

J Mol Biol. 1989 Jun 20;207(4):829-32.

PMID:
2760932
24.

Identical linkage and cooperativity of oxygen and carbon monoxide binding to Octopus dofleini hemocyanin.

Connelly PR, Gill SJ, Miller KI, Zhou G, van Holde KE.

Biochemistry. 1989 Feb 21;28(4):1835-43.

PMID:
2719937
25.

Nested allosteric interaction in tarantula hemocyanin revealed through the binding of oxygen and carbon monoxide.

Decker H, Connelly PR, Robert CH, Gill SJ.

Biochemistry. 1988 Sep 6;27(18):6901-8.

PMID:
3196690
26.

Analysis and parameter resolution in highly cooperative systems.

Gill SJ, Connelly PR, Di Cera E, Robert CH.

Biophys Chem. 1988 Jun;30(2):133-41.

PMID:
3416040
27.

Carbon monoxide binding to human hemoglobin A0.

Di Cera E, Doyle ML, Connelly PR, Gill SJ.

Biochemistry. 1987 Oct 6;26(20):6494-502.

PMID:
3427020
28.

Analysis of zeros of binding polynomials for tetrameric hemoglobins.

Connelly PR, Robert CH, Briggs WE, Gill SJ.

Biophys Chem. 1986 Aug;24(3):295-309.

PMID:
3768473

Supplemental Content

Loading ...
Support Center