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Items: 1 to 50 of 84

1.

Elevated Radiotherapy Toxicity in the Setting of Germline PTEN Mutation.

Tatebe K, Chmura SJ, Connell PP.

Pract Radiat Oncol. 2019 Jun 8. pii: S1879-8500(19)30163-8. doi: 10.1016/j.prro.2019.06.001. [Epub ahead of print]

PMID:
31185301
2.

The Visual Outcomes of Macular Hole Surgery: A Registry-Based Study by the Australian and New Zealand Society of Retinal Specialists.

Essex RW, Hunyor AP, Moreno-Betancur M, Yek JTO, Kingston ZS, Campbell WG, Connell PP, McAllister IL; Australian and New Zealand Society of Retinal Specialists Macular Hole Study Group.

Ophthalmol Retina. 2018 Nov;2(11):1143-1151. doi: 10.1016/j.oret.2018.04.022. Epub 2018 Jun 28.

PMID:
31047553
3.

Optimization of Drug Candidates That Inhibit the D-Loop Activity of RAD51.

Budke B, Tueckmantel W, Miles K, Kozikowski AP, Connell PP.

ChemMedChem. 2019 May 17;14(10):1031-1040. doi: 10.1002/cmdc.201900075. Epub 2019 Apr 17.

PMID:
30957434
4.

Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.

Chlenski A, Park C, Dobratic M, Salwen HR, Budke B, Park JH, Miller R, Applebaum MA, Wilkinson E, Nakamura Y, Connell PP, Cohn SL.

Mol Cancer Ther. 2019 Mar;18(3):507-516. doi: 10.1158/1535-7163.MCT-18-0819. Epub 2019 Jan 23.

PMID:
30674566
5.

MANAGEMENT OF GIANT RETINAL TEARS USING TRANSSCLERAL DIODE LASER RETINOPEXY AND SHORT-TERM POSTOPERATIVE TAMPONADE WITH PERFLUORO-N-OCTANE.

Bhardwaj G, Connell PP, Campbell WG.

Retina. 2018 Dec 18. doi: 10.1097/IAE.0000000000002424. [Epub ahead of print]

PMID:
30576303
6.

SURGICAL MANAGEMENT OF TRAUMATIC MACULAR HOLE: Optical Coherence Tomography Features and Outcomes.

Tang YF, Chang A, Campbell WG, Connell PP, Hunyor AP, McAllister IL, Essex RW; Australian and New Zealand Society of Retinal Specialists (ANZSRS) Macular Hole Study Group.

Retina. 2018 Nov 16. doi: 10.1097/IAE.0000000000002382. [Epub ahead of print]

PMID:
30475790
7.

Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors.

Lidgerwood GE, Morris AJ, Conquest A, Daniszewski M, Rooney LA, Lim SY, Hernández D, Liang HH, Allen P, Connell PP, Guymer RH, Hewitt AW, Pébay A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jul;1863(7):750-761. doi: 10.1016/j.bbalip.2018.04.007. Epub 2018 Apr 13.

PMID:
29660533
8.

Retuning the Radio in Radiobiology.

Chmura SJ, Connell PP, Weichselbaum RR.

J Natl Cancer Inst. 2018 Apr 1;110(4):325-326. doi: 10.1093/jnci/djx234. No abstract available.

PMID:
29126281
9.

Effect of Endoscopic Bronchial Ultrasound on Outcomes for Stage I Non-Small-Cell Lung Cancer Patients Receiving Hypofractionated Radiotherapy.

Akthar AS, Koshy M, Ferguson MK, Murgu S, Hogarth DK, Golden DW, Connell PP, Davies EM, Kowalski E, Malik R.

Clin Lung Cancer. 2018 Mar;19(2):e227-e233. doi: 10.1016/j.cllc.2017.08.003. Epub 2017 Aug 31.

PMID:
28939097
10.

A template for reducing ophthalmology outpatient waiting times: community ophthalmic care.

Goetz RK, Hughes FE, Duignan ES, O'Neill EC, Connell PP, Fulcher TP, Treacy MP.

Ir J Med Sci. 2018 Feb;187(1):237-241. doi: 10.1007/s11845-017-1630-z. Epub 2017 May 24.

PMID:
28540627
11.

Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer.

Pitroda SP, Bao R, Andrade J, Weichselbaum RR, Connell PP.

Clin Cancer Res. 2017 Aug 1;23(15):4493-4500. doi: 10.1158/1078-0432.CCR-16-2845. Epub 2017 Mar 24.

12.

Recent Developments Using Small Molecules to Target RAD51: How to Best Modulate RAD51 for Anticancer Therapy?

Budke B, Lv W, Kozikowski AP, Connell PP.

ChemMedChem. 2016 Nov 21;11(22):2468-2473. doi: 10.1002/cmdc.201600426. Epub 2016 Oct 26. Review.

13.

Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51.

Lv W, Budke B, Pawlowski M, Connell PP, Kozikowski AP.

J Med Chem. 2016 May 26;59(10):4511-25. doi: 10.1021/acs.jmedchem.5b01762. Epub 2016 Apr 21.

14.

The Effect of Postoperative Face-Down Positioning and of Long- versus Short-Acting Gas in Macular Hole Surgery: Results of a Registry-Based Study.

Essex RW, Kingston ZS, Moreno-Betancur M, Shadbolt B, Hunyor AP, Campbell WG, Connell PP, McAllister IL; Australian and New Zealand Society of Retinal Specialists Macular Hole Study Group.

Ophthalmology. 2016 May;123(5):1129-36. doi: 10.1016/j.ophtha.2015.12.039. Epub 2016 Feb 23. Erratum in: Ophthalmology. 2017 Jun;124(6):922-923.

PMID:
26920098
15.

Opportunistic detection of glaucomatous optic discs within a diabetic retinopathy screening service.

Treacy MP, O'Neill EC, Murphy M, O'Toole L, Delaney Y, O'Brien C, Connell PP.

Eur J Ophthalmol. 2016 Jun 10;26(4):315-20. doi: 10.5301/ejo.5000722. Epub 2015 Dec 17.

PMID:
26692063
16.

Strategies to Overcome Late Complications from Radiotherapy for Childhood Head and Neck Cancers.

Spiotto MT, Connell PP.

Oral Maxillofac Surg Clin North Am. 2016 Feb;28(1):115-26. doi: 10.1016/j.coms.2015.07.009. Review.

PMID:
26614704
17.

Objective assessment of symptomatic vitreous floaters using optical coherence tomography: a case report.

Kennelly KP, Morgan JP, Keegan DJ, Connell PP.

BMC Ophthalmol. 2015 Mar 8;15:22. doi: 10.1186/s12886-015-0003-5.

18.

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.

Mason JM, Dusad K, Wright WD, Grubb J, Budke B, Heyer WD, Connell PP, Weichselbaum RR, Bishop DK.

Nucleic Acids Res. 2015 Mar 31;43(6):3180-96. doi: 10.1093/nar/gkv175. Epub 2015 Mar 12.

19.

A genetic variant regulating miR-126 is associated with sight threatening diabetic retinopathy.

McAuley AK, Dirani M, Wang JJ, Connell PP, Lamoureux EL, Hewitt AW.

Diab Vasc Dis Res. 2015 Mar;12(2):133-8. doi: 10.1177/1479164114560160. Epub 2015 Jan 23.

PMID:
25616704
20.

Risk factors, microbial profiles and prognosis of microbial keratitis-associated endophthalmitis in high-risk eyes.

O'Neill EC, Yeoh J, Fabinyi DC, Cassidy D, Vajpayee RB, Allen P, Connell PP.

Graefes Arch Clin Exp Ophthalmol. 2014 Sep;252(9):1457-62. doi: 10.1007/s00417-014-2732-1. Epub 2014 Jul 17.

PMID:
25030241
21.

The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors.

Mason JM, Logan HL, Budke B, Wu M, Pawlowski M, Weichselbaum RR, Kozikowski AP, Bishop DK, Connell PP.

Cancer Res. 2014 Jul 1;74(13):3546-55. doi: 10.1158/0008-5472.CAN-13-3220. Epub 2014 Apr 21.

22.

DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.

Pitroda SP, Pashtan IM, Logan HL, Budke B, Darga TE, Weichselbaum RR, Connell PP.

Sci Transl Med. 2014 Mar 26;6(229):229ra42. doi: 10.1126/scitranslmed.3008291.

23.

Vitreous biomarkers in diabetic retinopathy: a systematic review and meta-analysis.

McAuley AK, Sanfilippo PG, Hewitt AW, Liang H, Lamoureux E, Wang JJ, Connell PP.

J Diabetes Complications. 2014 May-Jun;28(3):419-25. doi: 10.1016/j.jdiacomp.2013.09.010. Epub 2013 Oct 4. Review.

PMID:
24630762
24.

Replication of genetic loci implicated in diabetic retinopathy.

McAuley AK, Wang JJ, Dirani M, Connell PP, Lamoureux E, Hewitt AW.

Invest Ophthalmol Vis Sci. 2014 Mar 19;55(3):1666-71. doi: 10.1167/iovs.13-13559.

PMID:
24526447
25.

Small molecule derived from a natural product that mitigates radiation injury.

Connell PP, Weichselbaum RR.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18355-6. doi: 10.1073/pnas.1318343110. Epub 2013 Nov 1. No abstract available.

26.

Real-time solution measurement of RAD51- and RecA-mediated strand assimilation without background annealing.

Budke B, Chan YL, Bishop DK, Connell PP.

Nucleic Acids Res. 2013 Jul;41(13):e130. doi: 10.1093/nar/gkt362. Epub 2013 May 10.

27.

New paradigms and future challenges in radiation oncology: an update of biological targets and technology.

Liauw SL, Connell PP, Weichselbaum RR.

Sci Transl Med. 2013 Feb 20;5(173):173sr2. doi: 10.1126/scitranslmed.3005148.

28.

An analysis of patient characteristics and clinical outcomes in primary pulmonary sarcoma.

Spraker MB, Bair E, Bair R, Connell PP, Mahmood U, Koshy M.

J Thorac Oncol. 2013 Feb;8(2):147-51. doi: 10.1097/JTO.0b013e318277401f.

29.

An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.

Budke B, Kalin JH, Pawlowski M, Zelivianskaia AS, Wu M, Kozikowski AP, Connell PP.

J Med Chem. 2013 Jan 10;56(1):254-63. doi: 10.1021/jm301565b. Epub 2012 Dec 26.

30.

RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells.

Budke B, Logan HL, Kalin JH, Zelivianskaia AS, Cameron McGuire W, Miller LL, Stark JM, Kozikowski AP, Bishop DK, Connell PP.

Nucleic Acids Res. 2012 Aug;40(15):7347-57. doi: 10.1093/nar/gks353. Epub 2012 May 9.

31.

Hypofractionated image-guided radiation therapy for patients with limited volume metastatic non-small cell lung cancer.

Hasselle MD, Haraf DJ, Rusthoven KE, Golden DW, Salgia R, Villaflor VM, Shah N, Hoffman PC, Chmura SJ, Connell PP, Vokes EE, Weichselbaum RR, Salama JK.

J Thorac Oncol. 2012 Feb;7(2):376-81. doi: 10.1097/JTO.0b013e31824166a5.

32.

Stereotactic body radiotherapy for multisite extracranial oligometastases: final report of a dose escalation trial in patients with 1 to 5 sites of metastatic disease.

Salama JK, Hasselle MD, Chmura SJ, Malik R, Mehta N, Yenice KM, Villaflor VM, Stadler WM, Hoffman PC, Cohen EE, Connell PP, Haraf DJ, Vokes EE, Hellman S, Weichselbaum RR.

Cancer. 2012 Jun 1;118(11):2962-70. doi: 10.1002/cncr.26611. Epub 2011 Oct 21.

33.

Stimulation of the human RAD51 nucleofilament restricts HIV-1 integration in vitro and in infected cells.

Cosnefroy O, Tocco A, Lesbats P, Thierry S, Calmels C, Wiktorowicz T, Reigadas S, Kwon Y, De Cian A, Desfarges S, Bonot P, San Filippo J, Litvak S, Cam EL, Rethwilm A, Fleury H, Connell PP, Sung P, Delelis O, Andréola ML, Parissi V.

J Virol. 2012 Jan;86(1):513-26. doi: 10.1128/JVI.05425-11. Epub 2011 Oct 19.

34.

Self-induced Elizabethkingia meningoseptica endophthalmitis: a case report.

Connell PP, Wickremasinghe S, Devi U, Waters MJ, Allen PJ.

J Med Case Rep. 2011 Jul 11;5:303. doi: 10.1186/1752-1947-5-303.

35.

A downside to apoptosis in cancer therapy?

Connell PP, Weichselbaum RR.

Nat Med. 2011 Jul 7;17(7):780-2. doi: 10.1038/nm0711-780. No abstract available.

PMID:
21738153
36.

Pathologic response rates following definitive dose image-guided chemoradiotherapy and resection for locally advanced non-small cell lung cancer.

Shumway D, Corbin K, Salgia R, Hoffman P, Villaflor V, Malik RM, Haraf DJ, Vigneswaren WT, Shaikh AY, Connell PP, Ferguson MK, Salama JK.

Lung Cancer. 2011 Dec;74(3):446-50. doi: 10.1016/j.lungcan.2011.05.003. Epub 2011 Jun 14.

PMID:
21676484
37.

Vitreous cavity haemorrhage post-vitrectomy for diabetic eye disease: the effect of perioperative anticoagulation and antiplatelet agents.

Fabinyi DC, O'Neill EC, Connell PP, Clark JB.

Clin Exp Ophthalmol. 2011 Dec;39(9):878-84. doi: 10.1111/j.1442-9071.2011.02575.x. Epub 2011 Jun 14.

PMID:
21631675
38.

Gaze behavior among experts and trainees during optic disc examination: does how we look affect what we see?

O'Neill EC, Kong YX, Connell PP, Ong DN, Haymes SA, Coote MA, Crowston JG.

Invest Ophthalmol Vis Sci. 2011 Jun 7;52(7):3976-83. doi: 10.1167/iovs.10-6912.

PMID:
21467174
39.

Prism therapy and visual rehabilitation in homonymous visual field loss.

O'Neill EC, Connell PP, O'Connor JC, Brady J, Reid I, Logan P.

Optom Vis Sci. 2011 Feb;88(2):263-8. doi: 10.1097/OPX.0b013e318205a3b8.

PMID:
21217411
40.

Endogenous endophthalmitis: 10-year experience at a tertiary referral centre.

Connell PP, O'Neill EC, Fabinyi D, Islam FM, Buttery R, McCombe M, Essex RW, Roufail E, Clark B, Chiu D, Campbell W, Allen P.

Eye (Lond). 2011 Jan;25(1):66-72. doi: 10.1038/eye.2010.145. Epub 2010 Oct 22.

41.

Endogenous endophthalmitis associated with intravenous drug abuse: seven-year experience at a tertiary referral center.

Connell PP, O'Neill EC, Amirul Islam FM, Buttery R, McCombe M, Essex RH, Roufail E, Lash S, Wolffe B, Clark B, Chiu D, Campbell W, Allen P.

Retina. 2010 Nov-Dec;30(10):1721-5. doi: 10.1097/IAE.0b013e3181dd6db6.

PMID:
20829741
42.

Antifibrotic activity of bevacizumab on human Tenon's fibroblasts in vitro.

O'Neill EC, Qin Q, Van Bergen NJ, Connell PP, Vasudevan S, Coote MA, Trounce IA, Wong TT, Crowston JG.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6524-32. doi: 10.1167/iovs.10-5669. Epub 2010 Jun 23.

PMID:
20574016
43.

The optic nerve head in acquired optic neuropathies.

O'Neill EC, Danesh-Meyer HV, Connell PP, Trounce IA, Coote MA, Mackey DA, Crowston JG.

Nat Rev Neurol. 2010 Apr;6(4):221-36. doi: 10.1038/nrneurol.2010.5. Epub 2010 Mar 9. Review.

PMID:
20212512
44.

Primary tumor necrosis predicts distant control in locally advanced soft-tissue sarcomas after preoperative concurrent chemoradiotherapy.

MacDermed DM, Miller LL, Peabody TD, Simon MA, Luu HH, Haydon RC, Montag AG, Undevia SD, Connell PP.

Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):1147-53. doi: 10.1016/j.ijrobp.2009.03.015. Epub 2009 Jul 4.

45.

The optic nerve head in hereditary optic neuropathies.

O'Neill EC, Mackey DA, Connell PP, Hewitt AW, Danesh-Meyer HV, Crowston JG.

Nat Rev Neurol. 2009 May;5(5):277-87. doi: 10.1038/nrneurol.2009.40. Review.

PMID:
19488085
46.

Advances in radiotherapy and implications for the next century: a historical perspective.

Connell PP, Hellman S.

Cancer Res. 2009 Jan 15;69(2):383-92. doi: 10.1158/0008-5472.CAN-07-6871. No abstract available.

47.

Risk factors for age-related maculopathy.

Connell PP, Keane PA, O'Neill EC, Altaie RW, Loane E, Neelam K, Nolan JM, Beatty S.

J Ophthalmol. 2009;2009:360764. doi: 10.1155/2009/360764. Epub 2009 Sep 6.

48.

Acute sixth nerve palsy in a young man, beware of the 'red herring'.

O'Neill EC, Connell PP, Kadare S, Tormey PT.

Ir J Med Sci. 2010 Jun;179(2):301-3. doi: 10.1007/s11845-008-0245-9. Epub 2008 Oct 24.

PMID:
18949533
49.

A chemical compound that stimulates the human homologous recombination protein RAD51.

Jayathilaka K, Sheridan SD, Bold TD, Bochenska K, Logan HL, Weichselbaum RR, Bishop DK, Connell PP.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15848-53. doi: 10.1073/pnas.0808046105. Epub 2008 Oct 7.

50.

The minim technique for diagnostic anterior chamber paracentesis.

Wertheim MS, Connell PP, Majid MA, Dick AD.

Eye (Lond). 2009 Jun;23(6):1491. doi: 10.1038/eye.2008.231. Epub 2008 Aug 8. No abstract available.

PMID:
18688263

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