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Items: 9

1.

Development of a stress response therapy targeting aggressive prostate cancer.

Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D.

Sci Transl Med. 2018 May 2;10(439). pii: eaar2036. doi: 10.1126/scitranslmed.aar2036.

2.

Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.

Gwinn DM, Lee AG, Briones-Martin-Del-Campo M, Conn CS, Simpson DR, Scott AI, Le A, Cowan TM, Ruggero D, Sweet-Cordero EA.

Cancer Cell. 2018 Jan 8;33(1):91-107.e6. doi: 10.1016/j.ccell.2017.12.003.

PMID:
29316436
3.

Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin.

Truillet C, Cunningham JT, Parker MFL, Huynh LT, Conn CS, Ruggero D, Lewis JS, Evans MJ.

Clin Cancer Res. 2017 Jun 15;23(12):3045-3052. doi: 10.1158/1078-0432.CCR-16-2448. Epub 2016 Dec 22.

4.

Differential Requirements for eIF4E Dose in Normal Development and Cancer.

Truitt ML, Conn CS, Shi Z, Pang X, Tokuyasu T, Coady AM, Seo Y, Barna M, Ruggero D.

Cell. 2015 Jul 2;162(1):59-71. doi: 10.1016/j.cell.2015.05.049. Epub 2015 Jun 18.

5.

Translational control of the cytosolic stress response by mitochondrial ribosomal protein L18.

Zhang X, Gao X, Coots RA, Conn CS, Liu B, Qian SB.

Nat Struct Mol Biol. 2015 May;22(5):404-10. doi: 10.1038/nsmb.3010. Epub 2015 Apr 13.

6.

Nutrient signaling in protein homeostasis: an increase in quantity at the expense of quality.

Conn CS, Qian SB.

Sci Signal. 2013 Apr 16;6(271):ra24. doi: 10.1126/scisignal.2003520.

7.

Viewing folding of nascent polypeptide chains from ribosomes.

Liu B, Conn CS, Qian SB.

Expert Rev Proteomics. 2012 Dec;9(6):579-81. doi: 10.1586/epr.12.57. No abstract available.

8.

mTOR signaling in protein homeostasis: less is more?

Conn CS, Qian SB.

Cell Cycle. 2011 Jun 15;10(12):1940-7. Epub 2011 Jun 15. Review.

9.

PI3K-mTORC1 attenuates stress response by inhibiting cap-independent Hsp70 translation.

Sun J, Conn CS, Han Y, Yeung V, Qian SB.

J Biol Chem. 2011 Feb 25;286(8):6791-800. doi: 10.1074/jbc.M110.172882. Epub 2010 Dec 22.

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